Table 1.

Treatment with PEITC induces apoptosis but not cell cycle arrest in HCT-116 cells

Treatment% Cells in
Sub-G0/G1G0/G1SG2-M
Control (DMSO)1.81 ± 0.1038.25 ± 0.7326.31 ± 2.8633.41 ± 2.50
1 μmol/L PEITC (24 h)4.42 ± 0.76 *38.29 ± 2.7225.34 ± 0.7632.26 ± 2.43
2.5 μmol/L PEITC (24 h)9.14 ± 0.42 *31.83 ± 1.9725.62 ± 1.0033.61 ± 0.81
1 μmol/L PEITC (48 h)8.55 ± 0.23 *37.08 ± 2.6726.16 ± 1.2428.29 ± 3.61
2.5 μmol/L PEITC (48 h)28.29 ± 2.60 *29.89 ± 0.9521.37 ± 1.0720.92 ± 1.44
  • NOTE: Results are mean ± SE (n = 3).

  • * Significantly different compared with control by one-way ANOVA followed by Dunnett's test.