Table 1.

Affected fractions and combination indices with 17-DMAG and triciribine or AG825, in combination, on LTEDaro or MCF-7aro at 48 h

Cell line17-DMAG (nmol/L)Triciribine (nmol/L)AG825 (╬╝mol/L)Affected fractionCombination index
LTEDaro155000.63430.708
1510000.71670.523
305000.77570.819
3010000.77540.823
MCF-7aro155000.5030.976
1510000.5551.041
305000.690.621
3010000.720.621
LTEDaro150300.45171.992
150500.82261.197
300300.63371.951
300500.92950.958
MCF-7aro150300.33111.677
150500.56511.166
300300.48391.459
300500.66921.066