Table 1.

Cancer metastases in orthotopic pancreatic cancer mouse model developed from mock and IL-13Rα2–transfected HPAF-II cells and mock and IL-13Rα2–silenced HS766T cells

Mouse no.Body weight (g)Tumor size (cm3)Lymph node metastasisLiver metastasisAscites
HPAF2 mock123.11.1920
218.91.3230
326.51.4730
424.41.0910
523.11.3200
623.61.2930
Average23.31.282.00.0
SD2.50.131.30.0
HPAF2 α2 transfected120.21.15281+
218.71.4781
319.71.38172
420.31.07136
526.21.19322+ (bloody)
621.51.07110
Average21.11.2218.2*2.0
SD2.70.179.72.1
Mouse no.Body weight (g)Tumor size (cm3)Lymph node metastasisLiver metastasisPeritoneal metastasis
HS766T mock118.90.78321+
217.70.85381+
319.80.91300+
418.31.09400+
Average18.70.9035.0§0.5
SD0.900.134.760.58
HS766T α2 silenced123.90.9100
221.81.0200
320.20.7800
426.40.9900
Average23.10.920.00.0
SD2.680.110.000.00
  • *P = 0.0023.

  • P = 0.04 compared with mock HPAF-II.

  • P = 0.02.

  • §P < 0.0001 compared with α2-silenced HS766T.