Table 1.

Mutational analysis of the S1P2 5′ sequences in DLBCL

TotalCell linesPrimary cases
n of cases mutated/tested (%) 28/106 (26%)5/20 (25%)23/86 (27%)
Mutation frequency*0.17%0.18%0.17%
n of single bp substitutions1052184
n of deletions+duplications918
Transitions/transversions (ratio)61/44 (1.38)16/5 (3.2)45/39 (1.15)
G+C/A+T mutations81/2417/464/20
  • *Calculated in the mutated cases only, considering two alleles/sample (1,200 bp × 2).