Table 4.

Association of the best single SNP in each gene to malignant and benign tumor risk (data set 1)

GeneBest Praw malignant versus controlsBest Praw benign versus controlsBest Praw malignant versus benign
BRCA20.0200.0320.97
BRCA10.00680.0860.027
FGFR20.0270.0680.067
TOX30.340.0510.023
CHEK20.600.370.41
MAP3K10.0440.0280.12
LSP10.0440.170.32
RCAS10.0380.25018
TP530.820.0360.14
ERBB20.750.280.44
Ncases285326
Ncontrols848450

Abbreviation: Praw, the best χ2 single SNP P value obtained for each gene. Nominal association (Praw < 0.05) is indicated in bold. None of the SNPs gives significant P values after Bonferroni correction.