Table 1.

The average number of HSCs remaining at LSC eradication depends on σ, but the mean time to LSC extinction depends on κ

VariableValueEmbedded ImageEmbedded Image (wk)
σ10.001,581*
5.00577*
2.5080*
1.252*
κ25.001,58118.05
12.501,58837.50
6.251,60381.43
3.131,637196.55
nL/(nL + nH)0.801,58118.05
0.9078118.25
0.9538918.35
0.997718.42

NOTE: We start with σ = 10, κ = 25, and nL/(nL + nH) = 0.8, varying each parameter in turn while holding the others constant at their initial values.

  • *When βL and κ are held constant, Embedded Image is not a function of σ.