Table 1.

FOXP3 TSDR demethylation levels in major leukocyte cell types as determined by qPCR

Blood cell typesqPCR result (% demethylated FOXP3 TSDR)
CD4+CD27+CD45RA+ naïve T cells6.2
CD4+CD27+CD45RA memory T cells10.86
CD8+CD27+CD45RA+ naïve cytotoxic T cells0.49
CD8+CD27+CD45RA memory cytotoxic T cells0.34
CD15+ granulocytes0.01
CD14+ monocytes0.06
CD56+ NK cells0.07
CD19+ naïve B cells1.96
CD19+ memory B cells1.34