Table 1.

Spearman's correlations between tumor HIF-1 activity parameters, tumor size, and ascorbate content

HIF-1α band densityGLUT-1 band densityBNIP3 band densityVEGF protein levels (pg/μg DNA)Size of tumor (mm)Ascorbate content (mg/100 g)
HIF-1α band densityrs1.0000.302*0.2500.326*0.367*−0.026
P0.0370.0900.0310.0120.861
n484847444648
GLUT-1 band densityrs0.302*1.0000.4710.1650.213−0.071
P0.0370.0010.2830.1500.627
n484947444749
BNIP3 band densityrs0.2500.4711.0000.1470.311*−0.139
P0.0900.0010.3420.0370.350
n474747444547
VEGF protein levels (pg/μg DNA)rs0.326*0.1650.1471.0000.296−0.408
P0.0310.2830.3420.0570.006
n444444444244
Size of tumor (mm)rs0.367*0.2130.311*0.2961.000−0.129
P0.0120.1500.0370.0570.376
n464745424949
Ascorbate content (mg/100 g)rs−0.026−0.071−0.139−0.408−0.1291.000
P0.8610.6270.3500.0060.376
n484947444951
  • *Correlation is significant at the 0.05 level (two-tailed).

  • Correlation is significant at the 0.01 level (two-tailed).