Table 2.

Relationship between estimated radiation dose and risk of first and second primary cancers

Solid tumors
Colon dose (Gy)Person years for time to first cancerNo. of first primary casesRR* (95% CI)Person years for time to second cancerNo. of second primary casesRR* (95% CI)
<0.005943,6305,5801.00 (reference)25,2274011.00 (reference)
0.005–0.491,056,9106,4241.03 (0.99–1.07)30,0454751.01 (0.88–1.15)
0.50–0.9982,7597001.42 (1.31–1.54)3,757551.01 (0.76–1.33)
1.00–1.9941,7704741.92 (1.74–2.10)2,146621.98 (1.51–2.59)
≥2.0013,9231882.53 (2.19–2.93)1,078382.47 (1.77–3.46)
ERR/Gy*0.65 (0.57–0.74)0.57 (0.36–0.82)
Leukemias
Marrow dose (Gy)Person years for time to first cancerNo. of first primary casesRR* (95% CI)Person years for time to second cancerNo. of second primary casesRR* (95% CI)
<0.005917,052951.00 (reference)24,48271.00 (reference)
0.005–0.491,062,5701171.16 (0.88–1.53)30,03160.75 (0.25–2.26)
0.50–0.9990,912192.08 (1.27–3.41)3,67144.35 (1.26–15.01)
1.00–1.9948,913214.07 (2.53–6.53)2,64446.33 (1.83–21.90)
≥2.0019,5502312.57 (7.94–19.88)1,42426.09 (1.24–29.88)
ERR/Gy*2.65 (1.78–3.78)3.70 (0.99–10.80)
  • *RR and ERR/Gy are adjusted for sex, city, attained age, age at time of bombing, and age at first cancer diagnosis (second primary cancer risk estimates only).

  • P < 0.05.