Table 1.

MRM transitions and ion optic parameters for the test compounds

CompoundES+ MS transition (m/z)+Cone voltage (V)Collision energy (V)
Nicotine163.1>1063515
Nicotine-methyl-D3166.1>1063515
Cotinine177.1>984020
Cotinine-methyl-D3180.1>1014020
3HC193.1>804020
3HC-methyl-D3196.1>804020
Nicotine-Gluc339.1>163.13015
Nicotine-methyl-D3-Gluc342.1>166.13015
Cotinine-Gluc353.1>177.13015
Cotinine-methyl-D3-Gluc356.1>180.13015
3HC-Gluc369.1>193.13015
3HC-(methyl-D3)-Gluc372.1>196.13015
Creatinine114.1>443015
D3-creatinine117.1>473015
Nicotine N′-oxide179.1>117.13530
Nicotine-(methyl-D3)-N′-oxide182>117.13530
Cotinine N-oxide193.1>964025
Cotinine-(methyl-D3)-N-oxide196.1>964025
4HPBA182>1093525