Table 1.

Clinical study summary and reovirus virology and neutralizing antibodies

Patient no.Stage (post prostatectomy)Gleason scorePSANeutralizing antibody titerMaximum toxicity gradePathologic response descriptors
InflamationApoptsisNecrosis
TB01pT3aN14 + 5Baseline, 10.11:2560+++
Week 11:4096
Week 21:4096
Week 3, 10.61:4096
TB02pT3b4 + 3Baseline, 11.1<1:800+0
Week 11:1024
Week 21:4096
Week 3, 10.01:2048
TB03pT2b3 + 4Baseline, 3.21:80000
Week 11:1024
Week 21:2048
Week 3, 1.51:256
TB04pT3a4 + 5Baseline, 4.0<1:80++0
Week 11:32
Week 21:512
Week 3, 4.11:512
TB05pT3a4 + 3Baseline, 7.41:320+++
Week 11:32
Week 21:1024
Week 3, 7.81:2048
TB06pT3a3 + 5Baseline, 14.0<1:80+00
Week 11:4096
Week 21:4096
Week 3, 15.61:2048