Table 1.

CCN1 induces expression of type-I interferon response gene in the presence and absence of OV

Without OVWith OV
Gene nameNo DoxDoxFold inducedPNo DoxDoxFold inducedP
IFNB2.38518.43211.1160.000922.56336.5251.6190.0302
STAT11.66813.7378.2360.00015.55652.4429.439<0.0001
IRF71.74813.7487.8650.032115.577229.88314.7580.0005
IRF12.086312.3635.9260.000121.15147.9012.2650.0086
PKR1.4375.8734.0870.00292.96925.2668.5100.0001
OAS216.77662.1533.7050.009492.739408.2864.402<0.0001
IRF94.92216.3793.2810.004232.29129.514.011<0.0001
STAT23.70511.4713.0960.006211.46576.7066.6900.0041
IFNA1.6584.2352.5540.038620.83532.9491.5810.0366
IRF31.3322.1721.6310.01012.8635.6931.9880.0013

Abbreviations: STAT, signal transducer and activator; Dox, doxycycline.