Table 1.

Correlation between RKIP and miRNA expression in human cancer

No. of patient samplesmiR-23amiR-24-2miR-27a
Cancer entity (n = 14)(total n = 4,342)CoefficientPCoefficientPCoefficientP
Lung squamous cell carcinoma (LUSC)104−0.1310.1860.1760.074−0.2910.003b
Lung adenocarcinoma (LUAD)447−0.201<0.001b−0.0210.6610.172<0.001b
Prostate adenocarcinoma (PRAD)493−0.190<0.001b−0.174<0.001b−0.0950.060
Kidney renal clear cell carcinoma (KIRC)162−0.280<0.001b−0.2240.004b−0.272<0.001b
Bladder urothelial carcinoma (BLCA)405−0.306<0.001b−0.187<0.001b−0.354<0.001b
Invasive breast carcinoma (BRCA)299−0.1880.001b−0.1410.015b−0.1580.006b
Ovarian serous cystadenocarcinoma (OV)513−0.1370.002b−0.0840.058−0.0510.253
Uterine corpus endometrial carcinoma (UCEC)174−0.0890.2420.0250.747−0.0980.196
Pancreatic adenocarcinoma (PAAD)179−0.492<0.001b−0.368<0.001b−0.297<0.001b
Liver hepatocellular carcinoma (LIHC)369−0.425<0.001b−0.277<0.001b−0.407<0.001b
Colon and rectal adenocarcinoma (COAD)780.10.3820.0010.9970.0730.526
Head and neck squamous cell carcinoma (HNSC)476−0.1040.023a−0.1260.006b−0.070.087
Skin cutaneous melanoma (SKCM)4470.0440.3540.0390.4120.0690.145
Glioblastoma multiforme (GBM)1960.0480.5060.0020.9750.0440.542
  • NOTE: Expression values of RKIP mRNA (as obtained by RNA Sequencing V2 RSEM, Affymetrix U133, or Agilent microarrays) and miRNAs (as obtained by miRNA arrays) were correlated using Spearman-Rho. Negative coefficients equal to inverse correlation.

  • aP < 0.05.

  • bP < 0.01.