Skip to main content
  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Computer Resources
      • Highly Cited Collection
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Early Career Award
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citations
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Cancer Research

Cancer Research

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Computer Resources
      • Highly Cited Collection
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Early Career Award
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citations
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

The AACR remains fully committed to supporting publishing operations throughout this challenging time, while still remaining flexible and supportive of the author, reviewer, and editor communities that we serve. If you have any questions or concerns, please reach out to a member of the AACR publishing staff.
Please visit the COVID-19 & Cancer Resource Center where COVID-related content is freely available.

 

Follow @CR_AACR on Twitter!

  • Current issue of Cancer Research
    Read the April 15th Issue!
  • Insights into the Links between MYC and 3D Chromatin Structure and Epigenetics Regulation
    Insights into the Links between MYC and 3D Chromatin Structure and Epigenetics Regulation: Implications for Cancer Therapy
    Fatemeh Amjadi-Moheb, Alireza Paniri and Haleh Akhavan-Niaki
  • Gut Microbiota Condition the Therapeutic Efficacy of Trastuzumab
    Gut Microbiota Condition the Therapeutic Efficacy of Trastuzumab in HER2-Positive Breast Cancer
    Martina Di Modica, et al.
  • T Cells Expanded from PD-1+ Peripheral Blood Lymphocytes
    T Cells Expanded from PD-1+ Peripheral Blood Lymphocytes Share More Clones with Paired Tumor-Infiltrating Lymphocytes
    Tiepeng Li, et al.
  • Cancer Research Cover Contest Winner
    Cancer Research Cover Contest
    The research community voted the December 1, 2020 cover as the winner of our Cover Contest. Congratulations to the authors of "Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors"
  • 1
  • 2
  • 3
  • 4
  • 5

From the Current Issue

  • Tumor Biology and Immunology | AuthorChoice
    YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer
    Hazel M. Quinn, Regina Vogel, Oliver Popp, Philipp Mertins, Linxiang Lan, Clemens Messerschmidt, Alexandro Landshammer, Kamil Lisek, Sophie Château-Joubert, Elisabetta Marangoni, Elle Koren, Yaron Fuchs and Walter Birchmeier
    Cancer Res April 15 2021 81 (8) 2116-2127; DOI:10.1158/0008-5472.CAN-20-2801

    These findings show that YAP cooperates with β-catenin in basal-like breast cancer to regulate CSCs and that targeting this interaction may be a novel CSC therapy for patients with basal-like breast cancer.

  • Translational Science
    T Cells Expanded from PD-1+ Peripheral Blood Lymphocytes Share More Clones with Paired Tumor-Infiltrating Lymphocytes
    Tiepeng Li, Lingdi Zhao, Yonghao Yang, Yao Wang, Yong Zhang, Jindong Guo, Guangyu Chen, Peng Qin, Benling Xu, Baozhen Ma, Fang Zhang, Yiman Shang, Qingjun Li, Kai Zhang, Dongfeng Yuan, Chaojie Feng, Yan Ma, Zhiyong Liu, Zhichao Tian, Hongle Li, Shengdian Wang and Quanli Gao
    Cancer Res April 15 2021 81 (8) 2184-2194; DOI:10.1158/0008-5472.CAN-20-2300

    This study harnesses the tumor reactivity of PD-1+ PBLs, developing a method to expand T cells from these clones as a potential therapeutic strategy and TIL substitute in patients with cancer.

  • Gut Microbiota Condition the Therapeutic Efficacy of Trastuzumab in HER2-Positive Breast Cancer
    Translational Science
    Gut Microbiota Condition the Therapeutic Efficacy of Trastuzumab in HER2-Positive Breast Cancer
    Martina Di Modica, Giorgio Gargari, Viola Regondi, Arianna Bonizzi, Stefania Arioli, Beatrice Belmonte, Loris De Cecco, Elena Fasano, Francesca Bianchi, Alessia Bertolotti, Claudio Tripodo, Laura Villani, Fabio Corsi, Simone Guglielmetti, Andrea Balsari, Tiziana Triulzi and Elda Tagliabue
    Cancer Res April 15 2021 81 (8) 2195-2206; DOI:10.1158/0008-5472.CAN-20-1659

    Evidence of gut microbiota involvement in trastuzumab efficacy represents the foundation for new therapeutic strategies aimed at manipulating commensal bacteria to improve response in trastuzumab-resistant patients.

See the Table of Contents


Recent Reviews

  • Review
    Insights into the Links between MYC and 3D Chromatin Structure and Epigenetics Regulation: Implications for Cancer Therapy
    Fatemeh Amjadi-Moheb, Alireza Paniri and Haleh Akhavan-Niaki
    Cancer Res April 15 2021 81 (8) 1925-1936; DOI:10.1158/0008-5472.CAN-20-3613

OnlineFirst Articles

  • mTOR drives renal cell carcinoma development via MAPKs
    Hongguang Wu, et al.
  • Targeting adenosine with ADA2 to inhibit tumor growth
    Lin Wang, et al.
  • SLFN11, TAK-243 response and ER stress
    Yasuhisa Murai, et al.
  • Microbiome effects in an in vivo ovarian cancer model
    Lixing Chen, et al.
Load more

Trending - Altmetric

No Altmetric data available.
Advertisement

Back to top
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About Cancer Research

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

Advertisement