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Articles

Tumors in the Invertebrates: A Review

Berta Scharrer and Margaret Szabó Lochhead
Berta Scharrer
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Margaret Szabó Lochhead
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DOI:  Published July 1950
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Summary

Phenomena related to neoplastic growth have been studied in a number of invertebrate phyla, and tumors of either epithelial or connective tissue origin have been reported in annelids, sipunculids, arthropods, molluscs, and ascidians. Evidence of the true neoplastic character of such alleged tumors is often scanty; reasonably convincing signs of malignancy are found only in a small number of reported cases.

A number of tumors described in representatives from various invertebrate groups may be classified as spontaneous growths, since their cause is unknown. In insects certain of the alleged tumors are known to be hereditary. Other factors reported to cause tumors or abnormal growths in invertebrates are parasites, endocrine imbalance, and disturbance of innervation. Carcinogens have been tried on a variety of invertebrates and have been reported to cause tumors only in molluscs. X-rays in suitable dosage are known to cause tumor-like growths or increase their incidence in insects (Drosophila).

Footnotes

  • ↵* Special Research Fellow, U.S. Public Health Service. Research grants from the American Cancer Society and The Anna Fuller Fund are gratefully acknowledged.

  • Received April 12, 1950.
  • ©1950 American Association for Cancer Research.
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July 1950
Volume 10, Issue 7
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Tumors in the Invertebrates: A Review
Berta Scharrer and Margaret Szabó Lochhead
Cancer Res July 1 1950 (10) (7) 403-419;

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Tumors in the Invertebrates: A Review
Berta Scharrer and Margaret Szabó Lochhead
Cancer Res July 1 1950 (10) (7) 403-419;
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Cancer Research Online ISSN: 1538-7445
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