Table of Contents

Articles

• Basic Sciences

  Chemical Enhancement of Viral Transformation in Syrian Hamster Embryo Cells by Gaseous and Volatile Chlorinated Methanes and Ethanes

  George G. Hatch, Patricia D. Mamay, Mark L. Ayer, Bruce C. Casto and Stephen Nesnow

  Cancer Res May 1 1983 43 (5) 1945-1950;

  
  
• Basic Sciences

  Cellular Uptake and Inhibition of DNA Synthesis by Dihydroxyanthraquinone and Two Analogues

  Akira Nishio and Edwin M. Uyeki

  Cancer Res May 1 1983 43 (5) 1951-1956;

  
  
• Basic Sciences

  Role of Suppressor Cells in Feline Leukemia Virus-associated Immunosuppression

  Marc Langweiler, Gary L. Cockerell and Fernando deNoronha

  Cancer Res May 1 1983 43 (5) 1957-1960;

  
  
• Basic Sciences

  Effect of Partition Coefficient on the Ability of Nitroimidazoles to Enhance the Cytotoxicity of 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea

  David G. Hirst, J. Martin Brown and Judith L. Hazlehurst

  Cancer Res May 1 1983 43 (5) 1961-1965;

  
  
• Basic Sciences

  Transforming Growth Factors in Solid Human Malignant Neoplasms

  Kent A. Nickell, Jaroslava Halper and Harold L. Moses

  Cancer Res May 1 1983 43 (5) 1966-1971;

  
  
• Basic Sciences

  Epithelial Tissue-derived Growth Factor-like Polypeptides

  Jaroslava Halper and Harold L. Moses

  Cancer Res May 1 1983 43 (5) 1972-1979;

  
  
• Basic Sciences

  Relationships between Chemotaxis, Chemotactic Modulators, and Cyclic Nucleotide Levels in Tumor Cells

  Shalini Mokashi, S. James Delikatny and F. William Orr

  Cancer Res May 1 1983 43 (5) 1980-1983;

  
  
• Basic Sciences

  Inhibition of Natural Killer Cell Activity by a Soluble Substance Released by Rat Peritoneal Cells

  Jacob Zighelboim, Alan Lichtenstein, Aron Bick and Robert Mickel

  Cancer Res May 1 1983 43 (5) 1984-1989;

  
  
• Basic Sciences

  Prominent Glutamine Oxidation Activity in Mitochondria of Hematopoietic Tumors

  Wafa H. Abou-Khalil, Adel A. Yunis and Samir Abou-Khalil

  Cancer Res May 1 1983 43 (5) 1990-1993;

  
  
• Basic Sciences

  Tumor-localizing Components of the Porphyrin Preparation Hematoporphyrin Derivative

  David Kessel and Ta-Hsu Chou

  Cancer Res May 1 1983 43 (5) 1994-1999;

  
  
• Basic Sciences

  Relationship between Incorporation of 9-β-d-Arabinofuranosyladenine in L1210 DNA and Cytotoxicity

  D. W. Kufe, P. P. Major, D. Munroe, M. Egan and D. Herrick

  Cancer Res May 1 1983 43 (5) 2000-2004;

  
  
• Basic Sciences

  Development of a Cell Kinetic Approach to Curative Therapy of Acute Myelocytic Leukemia in Remission Using the Cell Cycle-specific Drug 1-β-d-Arabinofuranosylcytosine in a Rat Model

  William P. Vaughan and Philip J. Burke

  Cancer Res May 1 1983 43 (5) 2005-2009;

  
  
• Basic Sciences

  Activation of Tumoricidal Properties in Human Blood Monocytes by Liposomes Containing Lipophilic Muramyl Tripeptide

  Eugenie S. Kleinerman, Kent L. Erickson, Alan J. Schroit, William E. Fogler and Isaiah J. Fidler

  Cancer Res May 1 1983 43 (5) 2010-2014;

  
  
• Basic Sciences

  Selective Protection of Nonmalignant Cells by a Novel Cell Surface Glycopeptide

  James E. McGee, Bradley Johnson, Robert Kinders and Terry C. Johnson

  Cancer Res May 1 1983 43 (5) 2015-2017;

  
  
• Basic Sciences

  Preclinical Trial of a Radiant Heat Device for Whole-Body Hyperthermia Using a Porcine Model

  H. Ian Robins, Jeffrey Grossman, Thomas E. Davis, James P. AuBuchon and Warren Dennis

  Cancer Res May 1 1983 43 (5) 2018-2022;

  
  
• Basic Sciences

  Relationship of Spontaneous Chemical Transformation of Arylsulfonylhydrazones of 2-Pyridinecarboxaldehyde 1-Oxide to Anticancer Activity

  David A. Shiba, Jesse A. May Jr. and Alan C. Sartorelli

  Cancer Res May 1 1983 43 (5) 2023-2029;

  
  
• Basic Sciences

  Predictive Values of the in Vivo Diffusion Chamber for Cyclophosphamide Treatment of L1210 Murine Leukemia

  Kenneth C. Anderson, Richard L. Humphrey and Lyle L. Sensenbrenner

  Cancer Res May 1 1983 43 (5) 2030-2033;

  
  
• Basic Sciences

  Evidence for a New Model of Tumor Progression from Carcinogenesis and Tumor Promotion Studies with 7-Bromomethylbenz[a]anthracene

  John D. Scribner, Norma K. Scribner, Barbara McKnight and N. Karle Mottet

  Cancer Res May 1 1983 43 (5) 2034-2041;

  
  
• Basic Sciences

  Selective Effect of Rous Sarcoma Virus src Gene Expression on Contractile Protein Synthesis in Chick Embryo Myotubes

  Christopher M. West and David Boettiger

  Cancer Res May 1 1983 43 (5) 2042-2046;

  
  
• Basic Sciences

  Sodium Ascorbate Enhancement of Carbidopa-Levodopa Methyl Ester Antitumor Activity against Pigmented B16 Melanoma

  Herbert F. Pierson and Gary G. Meadows

  Cancer Res May 1 1983 43 (5) 2047-2051;

  
  
• Basic Sciences

  Formation of DNA Adducts in Vitro and in Salmonella typhimurium upon Metabolic Reduction of the Environmental Mutagen 1-Nitropyrene

  Paul C. Howard, Robert H. Heflich, Frederick E. Evans and Frederick A. Beland

  Cancer Res May 1 1983 43 (5) 2052-2058;

  
  
• Basic Sciences

  Toxicity of Aziridinylbenzoquinone for Aerobic and Hypoxic Cells of a Transplanted Mouse Mammary Tumor and Interaction of the Drug with Radiation and Adriamycin

  Ian Tannock

  Cancer Res May 1 1983 43 (5) 2059-2062;

  
  
• Basic Sciences

  Differences in the Sensitivities of Murine Metastatic Lymphoma/Lymphosarcoma Variants to Macrophage-mediated Cytolysis and/or Cytostasis

  Karen M. Miner and Garth L. Nicolson

  Cancer Res May 1 1983 43 (5) 2063-2067;

  
  
• Basic Sciences

  Use of Phenobarbital and High Doses of 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea in the Treatment of Brain Tumor-bearing Mice

  Paul J. Muller, Charles H. Tator and Martin L. Bloom

  Cancer Res May 1 1983 43 (5) 2068-2071;

  
  
• Basic Sciences

  Thermal Sensitivity and Thermotolerance in Normal Porcine Tissues

  Alvaro A. Martinez, Asher Meshorer, John L. Meyer, George M. Hahn, Luis F. Fajardo and Stavros D. Prionas

  Cancer Res May 1 1983 43 (5) 2072-2075;

  
  
• Basic Sciences

  Effects of Laser Irradiation on Hematoporphyrin-treated Normal and Transformed Thyroid Cells in Culture

  Alessandra Andreoni, Rinaldo Cubeddu, Sandro De Silvestri, Paolo Laporta, F. Saverio Ambesi-Impiombato, Mario Esposito, Michele Mastrocinque and Donatella Tramontano

  Cancer Res May 1 1983 43 (5) 2076-2080;

  
  
• Basic Sciences

  Effects of Calcium Depletion on Human Cells in Vitro and the Anomalous Behavior of the Human Melanoma Cell Line MM170

  Peter G. Parsons, Peter Musk, Patricia D. Goss and John Leah

  Cancer Res May 1 1983 43 (5) 2081-2087;

  
  
• Basic Sciences

  Low Colony Formation in Vivo and in Culture as Exhibited by Metastatic Melanoma Cells Selected for Reduced Homotypic Aggregation

  Reuben Lotan and Avraham Raz

  Cancer Res May 1 1983 43 (5) 2088-2093;

  
  
• Basic Sciences

  Action of Epidermal Growth Factor and Retinoids on Anchorage-dependent and -independent Growth of Nontransformed Rat Kidney Cells

  Anton M. Jetten and Ronald H. Goldfarb

  Cancer Res May 1 1983 43 (5) 2094-2099;

  
  
• Basic Sciences

  Mitochondrial Inclusions in Selenium-treated Mouse Mammary Epithelial Cell Lines

  Daniel Medina, F. Miller, C. J. Oborn and B. B. Asch

  Cancer Res May 1 1983 43 (5) 2100-2105;

  
  
• Basic Sciences

  Extraction of a Melanoma Growth-stimulatory Activity from Culture Medium Conditioned by the Hs0294 Human Melanoma Cell Line

  Ann Richmond, David H. Lawson, Daniel W. Nixon, J. Stedman Stevens and Rajender K. Chawla

  Cancer Res May 1 1983 43 (5) 2106-2112;

  
  
• Basic Sciences

  Detection of a Human Sarcoma-associated Antigen with Monoclonal Antibodies

  John M. Brown

  Cancer Res May 1 1983 43 (5) 2113-2120;

  
  
• Basic Sciences

  Effect of Rous Sarcoma Virus Transformation of Rat-1 Fibroblasts upon Their Growth Factor and Anchorage Requirements in Serum-free Medium

  Louis Giguère and Denis Gospodarowicz

  Cancer Res May 1 1983 43 (5) 2121-2130;

  
  
• Basic Sciences

  Heterogeneity of Sialoglycoproteins Purified from Normal and Malignant Cells

  Bradley S. Litin and William J. Grimes

  Cancer Res May 1 1983 43 (5) 2131-2137;

  
  
• Basic Sciences

  Alteration in Gene Expression at the Onset of Hormone-dependent Mammary Tumor Regression

  Freesia L. Huang and Yoon Sang Cho-Chung

  Cancer Res May 1 1983 43 (5) 2138-2142;

  
  
• Basic Sciences

  Characterization of Nucleolar Antigens of Normal Rat Liver, Regenerating Rat Liver, and Novikoff Ascites Hepatoma Cells following in Vitro Translation of Polyadenylic Acid-containing Messenger RNA

  Kimihiko Satoh and Harris Busch

  Cancer Res May 1 1983 43 (5) 2143-2149;

  
  
• Basic Sciences

  Effect of High and Low Dietary Protein on the Dosing and Postdosing Periods of Aflatoxin B₁-induced Hepatic Preneoplastic Lesion Development in the Rat

  B. Scott Appleton and T. Colin Campbell

  Cancer Res May 1 1983 43 (5) 2150-2154;

  
  
• Basic Sciences

  Establishment of Dihydrofolate Reductase-increased Human Cell Lines and Relationship between Dihydrofolate Reductase Levels and Gene Copy

  Barbara A. Domin, Susan P. Grill and Yung-chi Cheng

  Cancer Res May 1 1983 43 (5) 2155-2158;

  
  
• Basic Sciences

  Angiogenesis-dependent Tumor Spread in Reinforced Fibrin Clot Culture

  Roberto F. Nicosia, Ruy Tchao and Joseph Leighton

  Cancer Res May 1 1983 43 (5) 2159-2166;

  
  
• Basic Sciences

  Isolation and Characterization of a Cloned Cell Line R3327H-G8-A₁ Derived from the Dunning R3327H Rat Adenocarcinoma

  Mary Anne Sestili, James S. Norris and Roy G. Smith

  Cancer Res May 1 1983 43 (5) 2167-2175;

  
  
• Basic Sciences

  Characterization of a Quantitative Assay for the in Vitro Transformation of Normal Human Diploid Fibroblasts to Anchorage Independence by Chemical Carcinogens

  Robert J. Zimmerman and John B. Little

  Cancer Res May 1 1983 43 (5) 2176-2182;

  
  
• Basic Sciences

  Characteristics of Human Diploid Fibroblasts Transformed in Vitro by Chemical Carcinogens

  Robert J. Zimmerman and John B. Little

  Cancer Res May 1 1983 43 (5) 2183-2189;

  
  
• Basic Sciences

  Ultrastructural Differentiation of a Clonal Human Embryonal Carcinoma Cell Line in Vitro

  Ivan Damjanov and Peter W. Andrews

  Cancer Res May 1 1983 43 (5) 2190-2198;

  
  
• Basic Sciences

  Isolation and Characterization of Casein-producing and -nonproducing Cell Populations from 7,12-Dimethylbenz(a)anthracene-induced Rat Mammary Carcinomas

  Mark L. Johnson, Joseph Levy and Jeffrey M. Rosen

  Cancer Res May 1 1983 43 (5) 2199-2209;

  
  
• Basic Sciences

  Combined Effects of Misonidazole, Microwave Hyperthermia, and X-Rays on the in Vivo Sister Chromatid Exchanges and Chromosomal Abnormalities of the dbrB Tumor and on the Survival of Its Host

  Ranjit Banerjee, Anna Goldfeder and Jyotirmay Mitra

  Cancer Res May 1 1983 43 (5) 2210-2215;

  
  
• Basic Sciences

  Isolation and Preliminary Characterization of an Adriamycin-resistant Murine Fibrosarcoma Cell Line

  Raffaella Giavazzi, Eric Scholar and Ian R. Hart

  Cancer Res May 1 1983 43 (5) 2216-2222;

  
  
• Basic Sciences

  Clonal Variation of MCF-7 Breast Cancer Cells in Vitro and in Athymic Nude Mice

  Katherine Seibert, Samir M. Shafie, Timothy J. Triche, Jacqueline J. Whang-Peng, Stephen J. O'Brien, Jeffrey H. Toney, Karen K. Huff and Marc E. Lippman

  Cancer Res May 1 1983 43 (5) 2223-2239;

  
  
• Basic Sciences

  Suppression of Tumorigenicity in Hybrids of Tumorigenic Chinese Hamster Cells and Diploid Mouse Fibroblasts: Dependence on the Presence of at Least Three Different Mouse Chromosomes and Independence of Hamster Genome Dosage

  Reinhold Schäfer, Heike Hoffmann and Klaus Willecke

  Cancer Res May 1 1983 43 (5) 2240-2246;

  
  
• Basic Sciences

  Arrest of in Vivo Growth of a Solid Leydig Cell Tumor by Prolonged Inhibition of Mitochondrial Protein Synthesis

  Coby van den Bogert, Bert H. J. Dontje and Albert M. Kroon

  Cancer Res May 1 1983 43 (5) 2247-2251;

  
  
• Basic Sciences

  Terminal Incorporation of 2′-Deoxyadenosine into Polyadenylate Segments of Polyadenylated RNA in G₁-Phase-arrested Human T-Lymphoblasts

  Richard F. Kefford, Richard M. Fox, Eric McCaims, Dale Fahey, George E. O. Muscat and Peter B. Rowe

  Cancer Res May 1 1983 43 (5) 2252-2257;

  
  
• Basic Sciences

  Effect of Prolonged Administration of Gastrin on Experimental Carcinogenesis in Rat Colon Induced by Intrarectal Instillation of N-Methyl-N′-nitro-N-nitrosoguanidine

  Masaharu Tatsuta, Hisako Yamamura, Makoto Ichii and Haruo Taniguchi

  Cancer Res May 1 1983 43 (5) 2258-2260;

  
  
• Basic Sciences

  Strain-specific Tumorigenesis in Mouse Skin Induced by the Carcinogen, 15,16-Dihydro-11-methylcyclopenta[a]phenanthren-17-one, and Its Relation to DNA Adduct Formation and Persistence

  Peter J. Abbott

  Cancer Res May 1 1983 43 (5) 2261-2266;

  
  
• Basic Sciences

  Potentiation of Vincristine and Adriamycin Effects in Human Hemopoietic Tumor Cell Lines by Calcium Antagonists and Calmodulin Inhibitors

  Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi and Yoshio Sakurai

  Cancer Res May 1 1983 43 (5) 2267-2272;

  
  
• Basic Sciences

  Epstein-Barr Virus-specific Leukocyte Migration Inhibition Reaction with Tumor Biopsy Extracts: Correlation with the Presence of Viral DNA

  Robert Szigeti, Ari K. Saemundsen, Ann-Christine Synnerholm, Gertrude Henle, Werner Henle and George Klein

  Cancer Res May 1 1983 43 (5) 2273-2276;

  
  
• Basic Sciences

  Kinetic Parameters of Aspartate Transcarbamylase in Human Normal and Tumoral Cell Lines

  Jean Baillon, Marcelle Guichard, Edmond P. Malaise and Guy Hervé

  Cancer Res May 1 1983 43 (5) 2277-2282;

  
  
• Basic Sciences

  Accelerated Progression to Autonomy of a Pregnancy-dependent Mouse Mammary Tumor (TPDMT-4) by Hormones

  Akio Matsuzawa, Tetsuya Kaneko and Yukiko Ikeda

  Cancer Res May 1 1983 43 (5) 2283-2289;

  
  
• Basic Sciences

  Increased DNA Binding of the Estrogen Receptor in an Estrogen-resistant Mammary Cancer

  Pierre Paul Baskevitch, Françoise Vignon, Claudie Bousquet and Henri Rochefort

  Cancer Res May 1 1983 43 (5) 2290-2297;

  
  
• Basic Sciences

  Relative in Vitro Stability of Ornithine Decarboxylase from Liver Preneoplastic Nodules and Hepatomas

  Enrico Gravela, Maria Franca Zuretti, Fulvia Papino and Luisa Sartorio

  Cancer Res May 1 1983 43 (5) 2298-2300;

  
  
• Basic Sciences

  Alteration of Immunogenicity of Xenogenized Tumor Cells in Syngeneic Rats by the Immune Responses to Virus-associated Antigens Produced on Immunizing Cells

  Masuo Hosokawa, Takeshi Okayasu, Kohichiro Ikeda, Hiroyuki Katoh, Yasuhiro Suzuki and Hiroshi Kobayashi

  Cancer Res May 1 1983 43 (5) 2301-2305;

  
  
• Basic Sciences

  Effects of 12-O-Tetradecanoylphorbol-13-acetate on the Proliferation and Differentiation of Normal and Leukemic Myeloid Progenitor Cells

  Keiya Ozawa, Yasusada Miura, Yasuo Hashimoto, Yoshiko Kimura, Akio Urabe and Fumimaro Takaku

  Cancer Res May 1 1983 43 (5) 2306-2310;

  
  
• Basic Sciences

  Effect of Pharmacological Doses of Estrogen on Ovary-independent Rat Mammary Carcinoma Containing Estrogen and Progesterone Receptors

  Hiroki Yoshida, Toshiyuki Fukuhara, Sadamu Yamashi, Aichi Yoshida, Ryo Fukunishi, Motomu Tsuji and Keishi Matsumoto

  Cancer Res May 1 1983 43 (5) 2311-2316;

  
  
• Basic Sciences

  Therapeutic Utility of Utilizing Low Doses of N-(Phosphonacetyl)-l-aspartic Acid in Combination with 5-Fluorouracil: A Murine Study with Clinical Relevance

  Daniel S. Martin, Robert L. Stolfi, Robert C. Sawyer, Sol Spiegelman, Ephraim S. Casper and Charles W. Young

  Cancer Res May 1 1983 43 (5) 2317-2321;

  
  
• Meeting Report

  Sapporo Cancer Seminar: Membrane-associated Alterations in Cancer—Biochemical Strategies against Cancer

  P. H. Black, Sen-itoroh Hakomori and L. Warren

  Cancer Res May 1 1983 43 (5) 2322-2323;

  
  
• Clinical Investigations

  Phase I and Clinical Pharmacological Evaluation of Biochemical Modulation of 5-Fluorouracil with N-(Phosphonacetyl)-l-aspartic Acid

  Ephraim S. Casper, Karen Vale, Linda J. Williams, Daniel S. Martin and Charles W. Young

  Cancer Res May 1 1983 43 (5) 2324-2329;

  
  
• Clinical Investigations

  HLA Antigens in Renal Cell Carcinoma

  Arlene F. Kantor, Joseph K. McLaughlin, William A. Blattner, Fritz H. Bach, William J. Blot, Leonard M. Schuman and Joseph F. Fraumeni Jr.

  Cancer Res May 1 1983 43 (5) 2330-2333;

  
  
• Clinical Investigations

  In Vitro Differentiation of Leukemic Progenitor Cells in Various Types of Acute Nonlymphocytic Leukemia

  Keiya Ozawa, Yasusada Miura, Toshio Suda, Kazuo Motoyoshi and Fumimaro Takaku

  Cancer Res May 1 1983 43 (5) 2334-2338;

  
  
• Clinical Investigations

  Radiation Sensitivity of Leukemic Progenitor Cells in Acute Nonlymphocytic Leukemia

  Keiya Ozawa, Yasusada Miura, Toshio Suda, Kazuo Motoyoshi and Fumimaro Takaku

  Cancer Res May 1 1983 43 (5) 2339-2341;

  
  
• Clinical Investigations

  Pharmacokinetics of Oral Methotrexate in Children

  Frank M. Balis, Jill L. Savitch and W. Archie Bleyer

  Cancer Res May 1 1983 43 (5) 2342-2345;

  
  
• Clinical Investigations

  Clinical Correlations of Leukemic Clonogenic Cell Chemosensitivity Assessed by in Vitro Continuous Exposure to Drugs

  Chan H. Park, Peter H. Wiernik, Francis S. Morrison, Mammo Amare, Kerry Van Sloten and Thomas R. Maloney

  Cancer Res May 1 1983 43 (5) 2346-2349;

  
  
• Clinical Investigations

  Response of Human Myeloid Leukemia Cells to Various Sources of Colony-stimulating Activity and Phytohemagglutinin-conditioned Medium

  Raymond Taetle, Alendry Caviles and James Koziol

  Cancer Res May 1 1983 43 (5) 2350-2357;

  
  
• Clinical Investigations

  Evaluation of the Immunological and Toxicological Properties of MVE-2 in Phase I Trials

  John J. Rinehart, Donn C. Young and James A. Neidhart

  Cancer Res May 1 1983 43 (5) 2358-2362;

  
  
• Clinical Investigations

  A New Simple Enzymatic Assay Method for Urinary Polyamines in Humans

  Shunichiro Kubota, Masato Okada, Kazutomo Imahori and Nakaaki Ohsawa

  Cancer Res May 1 1983 43 (5) 2363-2367;

  
  
• Clinical Investigations

  Association of Hypercalcemia with Tumors Producing Colony-stimulating Factor(s)

  Yukio Kondo, Kanji Sato, Hiroyuki Ohkawa, Yoshito Ueyama, Tetsuro Okabe, Noriharu Sato, Shigetaka Asano, Mayumi Mori, Nakaaki Ohsawa and Kinori Kosaka

  Cancer Res May 1 1983 43 (5) 2368-2374;

  
  
• Meeting Report

  Fourth International Symposium on Nasopharyngeal Carcinoma Application of Field and Laboratory Studies to the Control of NPC

  D. V. Ablashi, P. H. Levine, U. Prasad and G. R. Pearson

  Cancer Res May 1 1983 43 (5) 2375-2378;

  
  
• Articles

  Announcements

  Cancer Res May 1 1983 43 (5) 2379-2380;

  
  
• Erratum

  Temperature Dependence of Adriamycin, cis-Diamminedichloroplatinum, Bleomycin, and 1,3-Bis(2-chloroethyl)-1-nitrosourea Cytotoxicity in Vitro

  Cancer Res May 1 1983 43 (5) 2381-2381;

  
  
• Erratum

  Renal Cell Carcinoma: Antitumor Effects of Leukocyte Interferon

  Cancer Res May 1 1983 43 (5) 2381-2381;

  
  
• Obituary

  Charles Heidelberger 1920–1983

  Elizabeth C. Miller and James A. Miller

  Cancer Res May 1 1983 43 (5) 2382-2382;