Table of Contents

Articles

• Basic Sciences

  Effect of Phorbol Ester Treatment on Drug-induced, Topoisomerase II-mediated DNA Cleavage in Human Leukemia Cells

  Leonard A. Zwelling, Diana Chan, Michael Hinds, Janice Mayes, Lynn E. Silberman and Mark Blick

  Cancer Res December 1 1988 48 (23) 6625-6633;

  
  
• Basic Sciences

  Influence of Mouse Major Histocompatibility Complex (H-2) on N-Ethyl-N-nitrosourea-induced Tumor Formation in Various Organs

  L. C. J. M. Oomen, M. A. van der Valk, A. A. M. Hart, P. Demant and P. Emmelot

  Cancer Res December 1 1988 48 (23) 6634-6641;

  
  
• Basic Sciences

  Effect of Different Levels of Omega-3 and Omega-6 Fatty Acids on Azoxymethane-induced Colon Carcinogenesis in F344 Rats

  Bandaru S. Reddy and S. Sugie

  Cancer Res December 1 1988 48 (23) 6642-6647;

  
  
• Basic Sciences

  Comparative Carcinogenesis by Nitrosomethylalkylamines in Syrian Hamsters

  W. Lijinsky and R. M. Kovatch

  Cancer Res December 1 1988 48 (23) 6648-6652;

  
  
• Basic Sciences

  MX2, a Morpholino Anthracycline, as a New Antitumor Agent against Drug-sensitive and Multidrug-resistant Human and Murine Tumor Cells

  Masahiko Watanabe, Nobuyasu Komeshima, Shohachi Nakajima and Takashi Tsuruo

  Cancer Res December 1 1988 48 (23) 6653-6657;

  
  
• Basic Sciences

  Overcoming Suppression of Antitumor Immune Reactivity in Tumor-bearing Rats by Treatment with Bleomycin

  Zhen-Yi Xu, Masuo Hosokawa, Kiyoshi Morikawa, Masanori Hatakeyama and Hiroshi Kobayashi

  Cancer Res December 1 1988 48 (23) 6658-6663;

  
  
• Basic Sciences

  Effect of l-Histidinol on the Metabolism of 5-Fluorouracil in the BALB/c × DBA/8 F₁ Murine Tumor System

  Robert C. Sawyer, Robert L. Stolfi and Daniel S. Martin

  Cancer Res December 1 1988 48 (23) 6664-6668;

  
  
• Basic Sciences

  Effects of Thioether Phospholipid BM 41.440 on Protein Kinase C and Phorbol Ester-induced Differentiation of Human Leukemia HL60 and KG-1 Cells

  Mamoru Shoji, Robert L. Raynor, Wolfgang E. Berdel, William R. Vogler and J. F. Kuo

  Cancer Res December 1 1988 48 (23) 6669-6673;

  
  
• Basic Sciences

  Changes in CuZn-Superoxide Dismutase during Induced Differentiation of Murine Erythroleukemia Cells

  Francesco Paoletti and Alessandra Mocali

  Cancer Res December 1 1988 48 (23) 6674-6677;

  
  
• Basic Sciences

  Isolation and Characterization of Colon Cancer Mucin from Xenografts of LS174T Cells

  James C. Byrd, Jeannette Nardelli, Bader Siddiqui and Young S. Kim

  Cancer Res December 1 1988 48 (23) 6678-6685;

  
  
• Basic Sciences

  Doxycycline in Combination Chemotherapy of a Rat Leukemia

  Coby Van den Bogert, Bert H. J. Dontje and Albert M. Kroon

  Cancer Res December 1 1988 48 (23) 6686-6690;

  
  
• Basic Sciences

  Insulin-like Growth Factor II mRNA Expression in Human Breast Cancer

  Douglas Yee, Kevin J. Cullen, Soonmyoung Paik, James F. Perdue, Brian Hampton, Arnold Schwartz, Marc E. Lippman and Neal Rosen

  Cancer Res December 1 1988 48 (23) 6691-6696;

  
  
• Basic Sciences

  Serotonin as a Major Serum Factor Inducing the Phospholipase C-mediated Hydrolysis of Phosphoinositides in Normal Rat Kidney Cells

  Yasuo Hamamori, Masahiko Hoshijima, Toshihiko Ohmori, Takashi Ueda and Yoshimi Takai

  Cancer Res December 1 1988 48 (23) 6697-6702;

  
  
• Basic Sciences

  Influence of cis-Diamminedichloroplatinum(II) on DNA Synthesis and Cell Cycle Progression in Excision Repair Proficient and Deficient Chinese Hamster Ovary Cells

  Christine M. Sorenson and Alan Eastman

  Cancer Res December 1 1988 48 (23) 6703-6707;

  
  
• Basic Sciences

  In Vitro and in Vivo Activation of B-Lymphocytes: A Flow Cytometric Study of Chromatin Structure Employing 7-Aminoactinomycin D

  Trond Stokke, Harald Holte and Harald B. Steen

  Cancer Res December 1 1988 48 (23) 6708-6714;

  
  
• Basic Sciences

  Investigation of the Effects of Heat Shock and Agents Which Induce a Heat Shock Response on the Induction of Differentiation of HL-60 Cells

  Frances M. Richards, Andrea Watson and John A. Hickman

  Cancer Res December 1 1988 48 (23) 6715-6720;

  
  
• Basic Sciences

  Lack of Correlation between Induction of Chemotactic Peptide Receptors and Stimulus-induced Actin Polymerization in HL-60 Cells Treated with Dibutyryl Cyclic Adenosine Monophosphate or Retinoic Acid

  K. Murali Krishna Rao, Mark S. Currie, J. Cullen Ruff and Harvey J. Cohen

  Cancer Res December 1 1988 48 (23) 6721-6726;

  
  
• Basic Sciences

  Membrane-associated Phosphatidylinositol Kinase of R3230AC Mammary Tumors and Normal Mammary Glands and Effects of Insulin on Tumor Enzyme Activity

  Uma Narayanan, Christopher Keuker and Russell Hilf

  Cancer Res December 1 1988 48 (23) 6727-6732;

  
  
• Basic Sciences

  Changes in c-myc, c-fms, and N-ras Proto-oncogene Expression Associated with Retinoic Acid-induced Monocytic Differentiation of Human Leukemia HL60/MRI Cells

  Masue Imaizumi and Theodore R. Breitman

  Cancer Res December 1 1988 48 (23) 6733-6738;

  
  
• Basic Sciences

  Relationship of Hepatic Peroxisome Proliferation and Replicative DNA Synthesis to the Hepatocarcinogenicity of the Peroxisome Proliferators Di(2-ethylhexyl)phthalate and [4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic Acid (Wy-14,643) in Rats

  Daniel S. Marsman, Russell C. Cattley, James G. Conway and James A. Popp

  Cancer Res December 1 1988 48 (23) 6739-6744;

  
  
• Basic Sciences

  Late Target Protein of the Carcinogen N-2-Fluorenylacetamide in Rat Liver

  Khan M. Munir, Gary R. Blackburn and Sam Sorof

  Cancer Res December 1 1988 48 (23) 6745-6752;

  
  
• Basic Sciences

  Enhanced Expression of c-myc and Epidermal Growth Factor Receptor (C-erbB-1) Genes in Primary Human Renal Cancer

  Masahiro Yao, Taro Shuin, Hiroshi Misaki and Yoshinobu Kubota

  Cancer Res December 1 1988 48 (23) 6753-6757;

  
  
• Basic Sciences

  Chemotactic Activity of Endothelial Cell-derived Interleukin 1 for Human Tumor Cells

  F. William Orr, Michael R. Buchanan, Victor A. Tron, David Guy, Davide Lauri and Daniel N. Sauder

  Cancer Res December 1 1988 48 (23) 6758-6763;

  
  
• Basic Sciences

  Differential Regulation of Growth and Invasiveness of MCF-7 Breast Cancer Cells by Antiestrogens

  Erik W. Thompson, Reuven Reich, Thomas B. Shima, Adriana Albini, Jeannette Graf, George R. Martin, Robert B. Dickson and Marc E. Lippman

  Cancer Res December 1 1988 48 (23) 6764-6768;

  
  
• Basic Sciences

  Monoclonal Antibodies Directed to a Disulfated Glycosphingolipid, S_B1a (GgOse₄Cer-II³IV³-bis-sulfate), Associated with Human Hepatocellular Carcinoma

  Nozomu Hiraiwa, Naoko Iida, Ineo Ishizuka, Shigeyuki Itai, Katsuyoshi Shigeta, Reiji Kannagi, Yoshihiro Fukuda and Hiroo Imura

  Cancer Res December 1 1988 48 (23) 6769-6774;

  
  
• Basic Sciences

  Patterns of Methionine Auxotrophy in Normal and Neoplastic Cells: The Methionine Independence of Lymphocyte Mitogenesis and Low Frequency of the Methionine-dependent Phenotype in Human Tumors

  Jean Gabriel Judde and Philip Frost

  Cancer Res December 1 1988 48 (23) 6775-6779;

  
  
• Basic Sciences

  Cyanoethylation of DNA in Vivo by 3-(Methylnitrosamino)propionitrile, an Areca-derived Carcinogen

  Bogdan Prokopczyk, Peter Bertinato and Dietrich Hoffmann

  Cancer Res December 1 1988 48 (23) 6780-6784;

  
  
• Basic Sciences

  Interactions of Thrombospondin with Sulfated Glycolipids and Proteoglycans of Human Melanoma Cells

  David D. Roberts

  Cancer Res December 1 1988 48 (23) 6785-6793;

  
  
• Basic Sciences

  Phototoxicity Mechanism of a Kryptocyanine Dye in Human Red Cell Membranes and Isolated Murine Mitochondria

  Oscar Valdes-Aguilera, Gulshan Ara and Irene E. Kochevar

  Cancer Res December 1 1988 48 (23) 6794-6798;

  
  
• Basic Sciences

  Mucin-like Carcinoma-associated Antigen Defined by Three Monoclonal Antibodies against Different Epitopes

  Christian Stähli, Mario Caravatti, Margreth Aeschbacher, Christine Kocyba, Béla Takacs and Heinz Carmann

  Cancer Res December 1 1988 48 (23) 6799-6802;

  
  
• Basic Sciences

  Characterization of a Human Small Cell Lung Carcinoma Cell Line with Acquired Resistance to cis-Diamminedichloroplatinum(II) in Vitro

  G. A. P. Hospers, N. H. Mulder, B. de Jong, L. de Ley, D. R. A. Uges, A. M. J. Fichtinger-Schepman, R. J. Scheper and E. G. E. de Vries

  Cancer Res December 1 1988 48 (23) 6803-6807;

  
  
• Basic Sciences

  Effects of the Aromatase Inhibitor 7α-(4′-Amino)phenylthio-4-androstene-3,17-dione on 7,12-Dimethylbenz(a)anthracene-induced Mammary Carcinoma in Rats

  Robert W. Brueggemeier and Pui-Kai Li

  Cancer Res December 1 1988 48 (23) 6808-6810;

  
  
• Basic Sciences

  Purification and Composition of the Human Tumor-associated Glycoprotein (TAG-72) Defined by Monoclonal Antibodies CC49 and B72.3

  Donald G. Sheer, Jeffrey Schlom and Herbert L. Cooper

  Cancer Res December 1 1988 48 (23) 6811-6818;

  
  
• Basic Sciences

  Involvement of the Polyamine Pathway in Antiestrogen-induced Growth Inhibition of Human Breast Cancer

  Fredric J. Cohen, Andrea Manni, Patricia Glikman, Mary Bartholomew and Laurence Demers

  Cancer Res December 1 1988 48 (23) 6819-6825;

  
  
• Basic Sciences

  Regulation of Tumor-induced Myelopoiesis and the Associated Immune Suppressor Cells in Mice Bearing Metastatic Lewis Lung Carcinoma by Prostaglandin E₂

  M. Rita I. Young, Melvin E. Young and Kimberly Kim

  Cancer Res December 1 1988 48 (23) 6826-6831;

  
  
• Basic Sciences

  Macrophage and Lymphocyte Potentiation of Syngeneic Tumor Cell and Host Fibroblast Collagenolytic Activity in Rats

  Mustafa K. Dabbous, Susan M. North, Lena Haney and Garth L. Nicolson

  Cancer Res December 1 1988 48 (23) 6832-6836;

  
  
• Basic Sciences

  Internucleosomal Cleavage and Chromosomal Degradation by Bleomycin and Phleomycin in Yeast

  C. W. Moore

  Cancer Res December 1 1988 48 (23) 6837-6843;

  
  
• Basic Sciences

  Differential Expression of Insulin-like Growth Factor II mRNA in Human Primary Liver Cancers, Benign Liver Tumors, and Liver Cirrhosis

  Elisabetta Cariani, Cantal Lasserre, Danielle Seurin, Bernard Hamelin, François Kemeny, Dominique Franco, Michael P. Czech, Axel Ullrich and Christian Brechot

  Cancer Res December 1 1988 48 (23) 6844-6849;

  
  
• Basic Sciences

  Characterization of Mouse Cell Lines Resistant to Nickel(II) Ions

  Xin Wei Wang, Richard J. Imbra and Max Costa

  Cancer Res December 1 1988 48 (23) 6850-6854;

  
  
• Basic Sciences

  Immunohistochemical and Biochemical Study of a Cathepsin B-like Proteinase in Human Colonic Cancers

  D. Keppler, M. C. Fondanèche, V. Dalet-Fumeron, M. Pagano and P. Burtin

  Cancer Res December 1 1988 48 (23) 6855-6862;

  
  
• Basic Sciences

  Influence of Organ Environment on the Growth, Selection, and Metastasis of Human Colon Carcinoma Cells in Nude Mice

  Kiyoshi Morikawa, Shirley M. Walker, Motowo Nakajima, Sen Pathak, J. Milburn Jessup and Isaiah J. Fidler

  Cancer Res December 1 1988 48 (23) 6863-6871;

  
  
• Basic Sciences

  Chemoprevention of N-Nitrosomethylbenzylamine-induced Esophageal Cancer in Rats by the Naturally Occurring Thioether, Diallyl Sulfide

  Michael J. Wargovich, Cynthia Woods, Vincent W. S. Eng, L. Clifton Stephens and Kenneth Gray

  Cancer Res December 1 1988 48 (23) 6872-6875;

  
  
• Basic Sciences

  A Murine Model of Experimental Metastasis to Bone and Bone Marrow

  Francisco Arguello, Raymond B. Baggs and Christopher N. Frantz

  Cancer Res December 1 1988 48 (23) 6876-6881;

  
  
• Basic Sciences

  Analysis of Hepatocyte Plasma Membrane Polarity during Rat Azo Dye Hepatocarcinogenesis Using Monoclonal Antibodies Directed against Domain-associated Antigens

  Jean-Yves Scoazec, Michèle Maurice, Alain Moreau and Gérard Feldmann

  Cancer Res December 1 1988 48 (23) 6882-6890;

  
  
• Basic Sciences

  Characterization of Three Small Cell Lung Cancer Cell Lines Established from One Patient during Longitudinal Follow-up

  Hendrikus H. Berendsen, Lou de Leij, Elisabeth G. E. de Vries, Geert Mesander, Nanno H. Mulder, Bouke de Jong, Charles H. C. M. Buys, Pieter E. Postmus, Sibrand Poppema, Henk J. Sluiter and Hauw T. The

  Cancer Res December 1 1988 48 (23) 6891-6899;

  
  
• Basic Sciences

  Tissue-specific Pharmacodynamics of 5-Bromo-2′-deoxyuridine Incorporation into DNA in VX2 Tumor-bearing Rabbits

  Philip L. Stetson, Jonathan Maybaum, John G. Wagner, Damon R. Averill, Ira S. Wollner, James A. Knol, Norma J. Johnson, Zhaomin Yang, Diane Preiskorn, Patricia Smith, Conrad A. Knutsen and William D. Ensminger

  Cancer Res December 1 1988 48 (23) 6900-6905;

  
  
• Basic Sciences

  A M_r 58,000 Glycoprotein Specifically Expressed in Developing Hamster Pancreas and Reexpressed in Hamster and Human Pancreatic Carcinomas

  A. Heredia and M. J. Escribano

  Cancer Res December 1 1988 48 (23) 6906-6911;

  
  
• Basic Sciences

  Induction of Lung and Exocrine Pancreas Tumors in F344 Rats by Tobacco-specific and Areca-derived N-Nitrosamines

  Abraham Rivenson, Dietrich Hoffmann, Bogdan Prokopczyk, Shantu Amin and Stephen S. Hecht

  Cancer Res December 1 1988 48 (23) 6912-6917;

  
  
• Basic Sciences

  Effect of Pretreatment with ICRF-187 on the Total Cumulative Dose of Doxorubicin Tolerated by Beagle Dogs

  E. H. Herman, V. J. Ferrans, R. S. K. Young and R. L. Hamlin

  Cancer Res December 1 1988 48 (23) 6918-6925;

  
  
• Basic Sciences

  Immunohistological and Functional Analyses of Lymphoid Infiltrates in Human Glioblastomas

  Maria Christina Kuppner, Marie France Hamou and Nicolas de Tribolet

  Cancer Res December 1 1988 48 (23) 6926-6932;

  
  
• Basic Sciences

  Quantitative in Vitro Assay for Tumor Cell Invasion through Extracellular Matrix or into Protein Gels

  Lars Johan Erkell and Volker Schirrmacher

  Cancer Res December 1 1988 48 (23) 6933-6937;

  
  
• Basic Sciences

  Immunohistochemical Characterization of Two Monoclonal Antibodies, P25.48 and P25.91, Which Define a New Prostate-specific Antigen

  Michel Bazinet, Richard J. Cote, Carlos Cordon-Cardo, Andrzej Myc, William R. Fair and Lloyd J. Old

  Cancer Res December 1 1988 48 (23) 6938-6942;

  
  
• Basic Sciences

  Inhibition of MCF-7 Cell Growth by 12-O-Tetradecanoylphorbol-13-acetate and 1,2-Dioctanoyl-sn-glycerol: Distinct Effects on Protein Kinase C Activity

  Marc Issandou, Francis Bayard and Jean-Marie Darbon

  Cancer Res December 1 1988 48 (23) 6943-6950;

  
  
• Clinical and Epidemiological Investigations

  Smoking and Lung Cancer in Women: Findings in a Prospective Study

  Lawrence Garfinkel and Steven D. Stellman

  Cancer Res December 1 1988 48 (23) 6951-6955;

  
  
• Clinical and Epidemiological Investigations

  Pharmacokinetics of 5-Fluorouracil Assessed with a Sensitive Mass Spectrometric Method in Patients on a Dose Escalation Schedule

  Cees J. van Groeningen, Herbert M. Pinedo, Jozef Heddes, Robert M. Kok, Adrianus P.J.M. de Jong, Evert Wattel, Godefridus J. Peters and Jan Lankelma

  Cancer Res December 1 1988 48 (23) 6956-6961;

  
  
• Letter to the Editor

  Correspondence re: L. F. Pearlman et al., Interaction of Three Second-Generation Anthracyclines with Polynucleotides, RNA, DNA, and Nucleosomes. Cancer Res., 46: 341–346, 1986

  Trond Stokke

  Cancer Res December 1 1988 48 (23) 6962-6963;

  
  
• Letter to the Editor

  Correspondence re: L. F. Pearlman et al., Interaction of Three Second-Generation Anthracyclines with Polynucleotides, RNA, DNA, and Nucleosomes. Cancer Res., 46: 341–346, 1986—Reply

  H. Simpkins, M. Figliomeni, L. Pearlman and M. Rosen

  Cancer Res December 1 1988 48 (23) 6963-6965;

  
  
• Articles

  Announcements

  Cancer Res December 1 1988 48 (23) 6966-6967;

  
  
• Erratum

  Expression of an Estramustine-binding Associated Protein in Human Lung Cancer Cell Lines

  Cancer Res December 1 1988 48 (23) 6968-6968;