Table of Contents

Articles

• Perspectives in Cancer Research

  Is There a Liver Stem Cell?

  Stewart Sell

  Cancer Res July 1 1990 50 (13) 3811-3815;

  
  
• Special Lecture

  Molecular Cytogenetics: Rosetta Stone for Understanding Cancer—Twenty-ninth G. H. A. Clowes Memorial Award Lecture

  Janet D. Rowley

  Cancer Res July 1 1990 50 (13) 3816-3825;

  
  
• Articles

  Interaction with Hyperthermia of Tetrachloroplatinum(II)(Nile Blue)₂ and Tetrachloroplatinum(II)(Neutral Red)₂ in EMT6 Murine Cells and the Murine FSaIIC Fibrosarcoma

  Terence S. Herman, Beverly A. Teicher, M. Raphael Pfeffer, Vrinda S. Khandekar and Timothy T. Korbut

  Cancer Res July 1 1990 50 (13) 3826-3831;

  
  
• Articles

  Prediction of Relapse and Survival in Breast Cancer Patients by pS2 Protein Status

  John A. Foekens, Marie-Christine Rio, Patrick Seguin, Wim L. J. van Putten, Joël Fauque, Marius Nap, Jan G. M. Klijn and Pierre Chambon

  Cancer Res July 1 1990 50 (13) 3832-3837;

  
  
• Articles

  Combined Modulation of S-Adenosylmethionine Biosynthesis and S-Adenosylhomocysteine Metabolism Enhances Inhibition of Nucleic Acid Methylation and L1210 Cell Growth

  Debora L. Kramer, Carl W. Porter, Ronald T. Borchardt and Janice R. Sufrin

  Cancer Res July 1 1990 50 (13) 3838-3842;

  
  
• Articles

  Comparison of the Fibronectin-binding Ability and Antitumor Efficacy of Various Mycobacteria

  M'Liss A. Hudson, Julie K. Ritchey, William J. Catalona, Eric J. Brown and Timothy L. Ratliff

  Cancer Res July 1 1990 50 (13) 3843-3847;

  
  
• Articles

  Genetic Analysis of Resistance to Radiation Lymphomagenesis with Recombinant Inbred Strains of Mice

  Masaaki Okumoto, Ryosuke Nishikawa, Syunsuke Imai and Jo Hilgers

  Cancer Res July 1 1990 50 (13) 3848-3850;

  
  
• Articles

  Major Histocompatibility Complex Class I and Unique Antigen Expression by Murine Tumors That Escaped from CD8⁺ T-Cell-dependent Surveillance

  Patricia L. Ward, Hartmut K. Koeppen, Teresa Hurteau, Donald A. Rowley and Hans Schreiber

  Cancer Res July 1 1990 50 (13) 3851-3858;

  
  
• Articles

  Relationship of Serum Levels of Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate to the Risk of Developing Postmenopausal Breast Cancer

  Gary B. Gordon, Trudy L. Bush, Kathy J. Helzlsouer, Susan R. Miller and George W. Comstock

  Cancer Res July 1 1990 50 (13) 3859-3862;

  
  
• Articles

  A Human Monocyte Growth Factor Produced by Lung Cancer Cells

  Tetsuro Okabe and Kaoru Yasukawa

  Cancer Res July 1 1990 50 (13) 3863-3865;

  
  
• Articles

  Effects of Estrogen on Cell Proliferation and Leukotriene Formation in Transformed Mouse Leydig Cells Cultured under Serum-free Conditions

  Yasuko Nishizawa, Kazumasa Nishii, Yoshio Nishizawa, Masafumi Koga, Susumu Kishimoto, Keishi Matsumoto and Bunzo Sato

  Cancer Res July 1 1990 50 (13) 3866-3871;

  
  
• Articles

  M_r 92,000 Gelatinase Release Correlates with the Metastatic Phenotype in Transformed Rat Embryo Cells

  Eric J. Bernhard, Ruth J. Muschel and Edward N. Hughes

  Cancer Res July 1 1990 50 (13) 3872-3877;

  
  
• Articles

  Combination Cytotoxic-Differentiation Therapy of Mouse Erythroleukemia Cells with 5-Fluorouracil and Hexamethylene Bisacetamide

  Samuel Waxman, Barbara M. Scher, Nella Hellinger and William Scher

  Cancer Res July 1 1990 50 (13) 3878-3887;

  
  
• Articles

  Expression of a M_r 32,000 Laminin-binding Protein Messenger RNA in Human Colon Carcinoma Correlates with Disease Progression

  Ken-ichi Mafune, T. S. Ravikumar, Jau Min Wong, Hsiukang Yow, Lan Bo Chen and Glenn D. Steele Jr.

  Cancer Res July 1 1990 50 (13) 3888-3891;

  
  
• Articles

  Voltage-operated Calcium Channels in Small Cell Lung Carcinoma Cell Lines: Pharmacological, Functional, and Immunological Properties

  Emanuele Sher, Atanasio Pandiella and Francesco Clementi

  Cancer Res July 1 1990 50 (13) 3892-3896;

  
  
• Articles

  Role of Natural Killer Cells and Macrophages in the Nonspecific Resistance to Tumors in Mice Stimulated with SMANCS, a Polymer-conjugated Derivative of Neocarzinostatin

  Fujio Suzuki, Richard B. Pollard, Satomi Uchimura, Tetsuo Munakata and Hiroshi Maeda

  Cancer Res July 1 1990 50 (13) 3897-3904;

  
  
• Articles

  Phase I and Clinical Pharmacological Evaluation of Pirozantrone Hydrochloride (Oxantrazole)

  Matthew M. Ames, Charles L. Loprinzi, Jerry M. Collins, Carol van Haelst-Pisani, Ronald L. Richardson, Joseph Rubin and Charles G. Moertel

  Cancer Res July 1 1990 50 (13) 3905-3909;

  
  
• Articles

  Kinetics of N-[(4-Chlorophenyl)amino]carbonyl-2,3-dihydro-1H-indene-5-sulfonamide (LY186641) in Humans

  Kenneth R. Hande, John Kuttesch, Marta Hamilton, Winston Satterlee, Linda Jackson, Gerald Grindey and John D. Hainsworth

  Cancer Res July 1 1990 50 (13) 3910-3914;

  
  
• Articles

  1,2-Dimethylhydrazine-induced Alterations in Protein Kinase C Activity in the Rat Preneoplastic Colon

  Charles L. Baum, Ramesh K. Wali, Michael D. Sitrin, Merry J. G. Bolt and Thomas A. Brasitus

  Cancer Res July 1 1990 50 (13) 3915-3920;

  
  
• Articles

  Elevated Pentose Cycle and Glucuronyltransferase in Daunorubicin-resistant P388 Cells

  Teresa Gessner, Lurine A. Vaughan, Blake C. Beehler, Christopher J. Bartels and Raymond M. Baker

  Cancer Res July 1 1990 50 (13) 3921-3927;

  
  
• Articles

  Prolonged Survival of Tumor-bearing Rats with Repetitive Low-Dose Recombinant Tumor Necrosis Factor

  Brett C. Sheppard, David Venzon, Douglas L. Fraker, Howard N. Langstein, J. Christian Jensen and Jeffrey A. Norton

  Cancer Res July 1 1990 50 (13) 3928-3933;

  
  
• Articles

  Modulation of Pro-Epidermal Growth Factor, Pro-Transforming Growth Factor α and Epidermal Growth Factor Receptor Gene Expression in Human Renal Carcinomas

  Petro E. Petrides, Susanne Bock, Jutta Bovens, Rainer Hofmann and Gerhard Jakse

  Cancer Res July 1 1990 50 (13) 3934-3939;

  
  
• Articles

  Influence of Dose of [6RS]Leucovorin on Reduced Folate Pools and 5-Fluorouracil-mediated Thymidylate Synthase Inhibition in Human Colon Adenocarcinoma Xenografts

  Janet A. Houghton, Larry G. Williams, Pamela J. Cheshire, Irving W. Wainer, Phillipe Jadaud and Peter J. Houghton

  Cancer Res July 1 1990 50 (13) 3940-3946;

  
  
• Articles

  Hormonal Modulation of HER-2/neu Protooncogene Messenger Ribonucleic Acid and p185 Protein Expression in Human Breast Cancer Cell Lines

  Linnea D. Read, Duane Keith Jr., Dennis J. Slamon and Benita S. Katzenellenbogen

  Cancer Res July 1 1990 50 (13) 3947-3951;

  
  
• Articles

  Serum Carcinoembryonic Antigen Level Increases Correlate with Tumor Progression in Patients with Differentiated Gastric Carcinoma following Noncurative Resection

  Yoshihiko Maehara, Keizo Sugimachi, Masanobu Akagi, Teruo Kakegawa, Hisaaki Shimazu and Masao Tomita

  Cancer Res July 1 1990 50 (13) 3952-3955;

  
  
• Articles

  Expression of a Nagao-type, Phosphatidylinositol-Glycan Anchored Alkaline Phosphatase in Human Choriocarcinomas

  Mark E. Lowe and Arnold W. Strauss

  Cancer Res July 1 1990 50 (13) 3956-3962;

  
  
• Articles

  Regulation of Protein Kinase C by Ionizing Radiation

  Gayle E. Woloschak, Chin-Mei Chang-Liu and Pocahontas Shearin-Jones

  Cancer Res July 1 1990 50 (13) 3963-3967;

  
  
• Articles

  A Neuropeptide Antagonist That Inhabits the Growth of Small Cell Lung Cancer in Vitro

  Penella J. Woll and Enrique Rozengurt

  Cancer Res July 1 1990 50 (13) 3968-3973;

  
  
• Articles

  Estrogen Receptor Gene Methylation in Human Breast Tumors

  Nicole S. Falette, Suzanne A. W. Fuqua, Gary C. Chamness, Marc S. Cheah, Geoffrey L. Greene and William L. McGuire

  Cancer Res July 1 1990 50 (13) 3974-3978;

  
  
• Articles

  Role of Substrate Depletion in the Inhibition of Thymidylate Biosynthesis by the Dihydrofolate Reductase Inhibitor Trimetrexate in Cultured Hepatoma Cells

  Myung S. Rhee, Malgorzata Balinska, Marlene Bunni, David G. Priest, Gladys F. Maley, Frank Maley and John Galivan

  Cancer Res July 1 1990 50 (13) 3979-3984;

  
  
• Articles

  Tissue Distribution and Photosensitizing Properties of Mono-l-aspartyl Chlorin e6 in a Mouse Tumor Model

  Charles J. Gomer and Angela Ferrario

  Cancer Res July 1 1990 50 (13) 3985-3990;

  
  
• Articles

  Association between Diet and Age-related DNA Modifications (I-Compounds) in Rat Liver and Kidney

  Donghui Li and Kurt Randerath

  Cancer Res July 1 1990 50 (13) 3991-3996;

  
  
• Articles

  Reversal of Multidrug Resistance by Lipophilic Drugs

  Eva Hofsli and Jon Nissen-Meyer

  Cancer Res July 1 1990 50 (13) 3997-4002;

  
  
• Articles

  Flow Cytometric DNA Ploidy Analysis of Feline Mammary Tumors

  Jules M. H. M. Minke, Cees J. Cornelisse, John A. M. Stolwijk, Nel J. Kuipers-Dijkshoorn, Gerard R. Rutteman and Wim Misdorp

  Cancer Res July 1 1990 50 (13) 4003-4007;

  
  
• Articles

  Cachectic Effects of Recombinant Human Tumor Necrosis Factor in Rats

  Gail Darling, Douglas L. Fraker, J. Christian Jensen, Catherine M. Gorschboth and Jeffrey A. Norton

  Cancer Res July 1 1990 50 (13) 4008-4013;

  
  
• Articles

  Mutational Analysis of the H-ras Oncogene in Spontaneous C57BL/6 × C3H/He Mouse Liver Tumors and Tumors Induced with Genotoxic and Nongenotoxic Hepatocarcinogens

  Tony R. Fox, Alan M. Schumann, Philip G. Watanabe, Barry L. Yano, Veronica M. Maher and J. Justin McCormick

  Cancer Res July 1 1990 50 (13) 4014-4019;

  
  
• Articles

  Selective Killing of Malignant Cells from Leukemic Patients by Alkyl-Lysophospholipid

  Leo F. Verdonck, Els O. Witteveen, Hans G. van Heugten, Erik Rozemuller and Gert Rijksen

  Cancer Res July 1 1990 50 (13) 4020-4025;

  
  
• Articles

  5-Fluorouracil Enhances Azidothymidine Cytotoxicity: In Vitro, in Vivo, and Biochemical Studies

  Isa Brunetti, Alfredo Falcone, Paul Calabresi, Frederick A. Goulette and James W. Darnowski

  Cancer Res July 1 1990 50 (13) 4026-4031;

  
  
• Articles

  Induction of Interleukin 3 and Tumor Resistance by SSM, a Cancer Immunotherapeutic Agent Extracted from Mycobacterium tuberculosis

  Hidetaka Sasaki, David Schmitt, Yoshiro Hayashi, Richard B. Pollard and Fujio Suzuki

  Cancer Res July 1 1990 50 (13) 4032-4037;

  
  
• Articles

  Effects of l-Phenylalanine Mustard and l-Buthionine Sulfoximine on Murine and Human Hematopoietic Progenitor Cells in Vitro

  De-Lin Du, Donna A. Volpe, Charles K. Grieshaber and Martin J. Murphy Jr.

  Cancer Res July 1 1990 50 (13) 4038-4043;

  
  
• Articles

  Characterization of Nonexchangeable Radioactivity in L1210 Cells Incubated with [¹⁴C]Thiotepa: Labeling of Phosphatidylethanolamine

  Merrill J. Egorin and Stuart W. Snyder

  Cancer Res July 1 1990 50 (13) 4044-4049;

  
  
• Articles

  Radiosensitivity of Skin Fibroblasts from Atomic Bomb Survivors with and without Breast Cancer

  Sadayuki Ban, Richard B. Setlow, Michael A Bender, Haruo Ezaki, Toshio Hiraoka, Motoi Yamane, Masayuki Nishiki, Kiyohiko Dohi, Akio A. Awa, Richard C. Miller, Dilys M. Parry, John J. Mulvihill and Gilbert W. Beebe

  Cancer Res July 1 1990 50 (13) 4050-4055;

  
  
• Articles

  Paradoxical Increase in DNA Cross-Linking in a Human Ovarian Carcinoma Cell Line Resistant to Cyanomorpholino Doxorubicin

  Derick H. M. Lau, Kevin L. Ross and Branimir I. Sikic

  Cancer Res July 1 1990 50 (13) 4056-4060;

  
  
• Articles

  Transient Alterations in the Expression of Protease and Extracellular Matrix Genes during Metastatic Lung Colonization by H-ras-transformed 10T½ Fibroblasts

  M. C. Gingras, L. Jarolim, J. Finch, G. T. Bowden, J. A. Wright and A. H. Greenberg

  Cancer Res July 1 1990 50 (13) 4061-4066;

  
  
• Articles

  Depletion of Cellular Glutathione by N,N′-Bis(trans-4-Hydroxycyclohexyl)-N′-nitrosourea as a Determinant of Sensitivity of K562 Human Leukemia Cells to 4-Hydroperoxycyclophosphamide

  Christine M. Chresta, Tim R. Crook and Robert L. Souhami

  Cancer Res July 1 1990 50 (13) 4067-4071;

  
  
• Articles

  Hepatic Neoplasms in Aflatoxin B₁-treated, Congenital Duck Hepatitis B Virus-infected, and Virus-free Pekin Ducks

  John M. Cullen, Patricia L. Marion, Glenn J. Sherman, Xin Hong and John E. Newbold

  Cancer Res July 1 1990 50 (13) 4072-4080;

  
  
• Articles

  Spontaneous Prolactin Transplantable Tumor in the Wistar/Furth Rat (SMtTW): A New Animal Model of Human Prolactinoma

  Jacqueline Trouillas, Christian Girod, Bruno Claustrat, Marie-Odile Joly-Pharaboz and Pascale Chevallier

  Cancer Res July 1 1990 50 (13) 4081-4086;

  
  
• Articles

  Overexpression of HER-2/neu Is Associated with Poor Survival in Advanced Epithelial Ovarian Cancer

  A. Berchuck, A. Kamel, R. Whitaker, B. Kerns, G. Olt, R. Kinney, J. T. Soper, R. Dodge, D. L. Clarke-Pearson, P. Marks, S. McKenzie, S. Yin and R. C. Bast Jr.

  Cancer Res July 1 1990 50 (13) 4087-4091;

  
  
• Articles

  Chromosome Aberrations in Uterine Smooth Muscle Tumors: Potential Diagnostic Relevance of Cytogenetic Instability

  Jonathan A. Fletcher, Cynthia C. Morton, Karen Pavelka and Janice M. Lage

  Cancer Res July 1 1990 50 (13) 4092-4097;

  
  
• Articles

  Cloning of Estrogen-responsive Messenger RNAs in the T-47D Human Breast Cancer Cell Line

  David L. Manning, Leslie H. Archibald and Kim T. Ow

  Cancer Res July 1 1990 50 (13) 4098-4104;

  
  
• Articles

  Monoclonal Antibody and F(ab′)₂ Fragment Delivery to Tumor in Patients with Glioma: Comparison of Intracarotid and Intravenous Administration

  Michael R. Zalutsky, Robin P. Moseley, Jonathan C. Benjamin, Edward V. Colapinto, Gregory N. Fuller, Hugh P. Coakham and Darrell D. Bigner

  Cancer Res July 1 1990 50 (13) 4105-4110;

  
  
• Articles

  B-Cell Growth Factor-induced and α-Interferon-inhibited Proliferation of Hairy Cells Coincides with Modulation of Cell Surface Antigens

  Haim Gamliel, Bernard H. Brownstein, Dorit Gurfel, Shi-Hua Wu, Michael C. Rosner and Harvey M. Golomb

  Cancer Res July 1 1990 50 (13) 4111-4120;

  
  
• Articles

  Retinoic Acid Inhibition of Human Melanoma Cell Invasion through a Reconstituted Basement Membrane and Its Relation to Decreases in the Expression of Proteolytic Enzymes and Motility Factor Receptor

  Mary J. C. Hendrix, W. Rebecca Wood, Elisabeth A. Seftor, Dafna Lotan, Motowo Nakajima, Ronald L. Misiorowski, Richard E. B. Seftor, William G. Stetler-Stevenson, Sandra J. Bevacqua, Lance A. Liotta, Mark E. Sobel, Avraham Raz and Reuben Lotan

  Cancer Res July 1 1990 50 (13) 4121-4130;

  
  
• Articles

  Tumor Angiogenesis and Polyamines: α-Difluoromethylornithine, an Irreversible Inhibitor of Ornithine Decarboxylase, Inhibits B16 Melanoma-induced Angiogenesis in Ovo and the Proliferation of Vascular Endothelial Cells in Vitro

  Masaharu Takigawa, Motomi Enomoto, Yukimitsu Nishida, Hai-Ou Pan, Akihiro Kinoshita and Fujio Suzuki

  Cancer Res July 1 1990 50 (13) 4131-4138;

  
  
• Articles

  Biological Characterization of Pseudocyst-forming Cell Lines from Human Adenoid Cystic Carcinomas of Minor Salivary Gland Origin

  Kanemitsu Shirasuna, Kazuya Watatani, Hideyuki Furusawa, Munehisa Saka, Shigeyuki Morioka, Hideo Yoshioka and Tokuzou Matsuya

  Cancer Res July 1 1990 50 (13) 4139-4145;

  
  
• Articles

  Amplification and Rearrangement of c-myc in Radiation-induced Murine Ostosarcomas

  Silvia A. Sturm, P. Günter Strauss, Sabine Adolph, Horst Hameister and Volker Erfle

  Cancer Res July 1 1990 50 (13) 4146-4153;

  
  
• Articles

  Phase I Clinical Comparative Study of Monoclonal Antibody KS1/4 and KS1/4-Methotrexate Immunconjugate in Patients with Non-Small Cell Lung Carcinoma

  Darlene J. Elias, Lynn Hirschowitz, Lawrence E. Kline, Joan F. Kroener, Robert O. Dillman, Leslie E. Walker, James A. Robb and Richard M. Timms

  Cancer Res July 1 1990 50 (13) 4154-4159;

  
  
• Articles

  Establishment and Characterization of Continuous Cell Line MTC-SK Derived from a Human Medullary Thyroid Carcinoma

  Roswitha Pfragner, Heinz Höfler, Annemarie Behmel, Elisabeth Ingolic and Veronika Walser

  Cancer Res July 1 1990 50 (13) 4160-4166;

  
  
• Articles

  Rhodamine 123 Phototoxicity in Laser-irradiated MGH-U1 Human Carcinoma Cells Studied in Vitro by Electron Microscopy and Confocal Laser Scanning Microscopy

  Christopher R. Shea, Margaret E. Sherwood, Thomas J. Flotte, Norah Chen, Manfred Scholz and Tayyaba Hasan

  Cancer Res July 1 1990 50 (13) 4167-4172;

  
  
• Articles

  Announcements

  Cancer Res July 1 1990 50 (13) 4173-4174;

  
  
• Erratum

  Expression of Human Chromosome 2 Ornithine Decarboxylase Gene in Ornithine Decarboxylase-deficient Chinese Hamster Ovary Cells

  Cancer Res July 1 1990 50 (13) 4174-4174;