Table of Contents

Articles

• Articles

  Flow Cytometric Analysis of DNA Damage and Repair in the Cells Resistant to Alkylating Agents

  Oskar S. Frankfurt, Daniel Seckinger and Everett V. Sugarbaker

  Cancer Res August 1 1990 50 (15) 4453-4457;

  
  
• Articles

  Inhibition of Growth Factor-dependent Inositol Phosphate Ca²⁺ Signaling by Antitumor Ether Lipid Analogues

  Markus J. Seewald, Richard A. Olsen, Inder Sehgal, Deborah C. Melder, Edward J. Modest and Garth Powis

  Cancer Res August 1 1990 50 (15) 4458-4463;

  
  
• Articles

  Pediatric Phase I Trial and Pharmacokinetic Study of Piritrexim Administered Orally on a Five-Day Schedule

  Peter C. Adamson, Frank M. Balis, James Miser, Robert J. Wells, W. Archie Bleyer, Thomas E. Williams, Andrea Gillespie, John S. Penta, Neil J. Clendeninn and David G. Poplack

  Cancer Res August 1 1990 50 (15) 4464-4467;

  
  
• Articles

  Development of Drug Resistance to Gallium Nitrate through Modulation of Cellular Iron Uptake

  Christopher R. Chitambar, Zorica Zivkovic-Gilgenbach, Jana Narasimhan and William E. Antholine

  Cancer Res August 1 1990 50 (15) 4468-4472;

  
  
• Articles

  Dependence of Indomethacin-induced Potentiation of Murine Tumor Radioresponse on Tumor Host Immunocompetence

  Luka Milas, Yuichi Furuta, Nancy Hunter, Iku Nishiguchi and Sanyukta Runkel

  Cancer Res August 1 1990 50 (15) 4473-4477;

  
  
• Articles

  Interstitial Pressure Gradients in Tissue-isolated and Subcutaneous Tumors: Implications for Therapy

  Yves Boucher, Laurence T. Baxter and Rakesh K. Jain

  Cancer Res August 1 1990 50 (15) 4478-4484;

  
  
• Articles

  Monoclonal Antibody and Synthetic Peptide Inhibitors of Human Tumor Cell Migration

  Kenneth M. Yamada, Dorothy W. Kennedy, Susan S. Yamada, Harvey Gralnick, Wen-Tien Chen and Steven K. Akiyama

  Cancer Res August 1 1990 50 (15) 4485-4496;

  
  
• Articles

  Dietary Indicators of Laryngeal Cancer Risk

  Carlo La Vecchia, Eva Negri, Barbara D'Avanzo, Silvia Franceschi, Adriano Decarli and Peter Boyle

  Cancer Res August 1 1990 50 (15) 4497-4500;

  
  
• Articles

  Photodynamic Therapy by Topical meso-Tetraphenylporphinesulfonate Tetrasodium Salt Administration in Superficial Basal Cell Carcinomas

  Olivia Santoro, Gaetano Bandieramonte, Elsa Melloni, Renato Marchesini, Franco Zunino, Paolo Lepera and Giuseppe De Palo

  Cancer Res August 1 1990 50 (15) 4501-4503;

  
  
• Articles

  Inverse Relationship of Epidermal Growth Factor Receptor and HER2/neu Gene Expression in Human Renal Cell Carcinoma

  Uwe Weidner, Stephan Peter, Torsten Strohmeyer, Rolf Hussnätter, Rolf Ackermann and Helmut Sies

  Cancer Res August 1 1990 50 (15) 4504-4509;

  
  
• Articles

  Effects of Three Irreversible Inhibitors of Ornithine Decarboxylase on Macrophage-mediated Tumoricidal Activity and Antitumor Activity in B16F1 Tumor-bearing Mice

  Terry L. Bowlin, Brenda J. Hoeper, Andrea L. Rosenberger, Gregory F. Davis and Prasad S. Sunkara

  Cancer Res August 1 1990 50 (15) 4510-4514;

  
  
• Articles

  Thermal Response of Oncogene-transfected Rat Cells

  Gloria C. Li, C. Clifton Ling, Brian Endlich and Johnson Y. Mak

  Cancer Res August 1 1990 50 (15) 4515-4521;

  
  
• Articles

  Potent Growth Inhibition of Human Tumor Cells in Culture by Arginine Deiminase Purified from a Culture Medium of a Mycoplasma-infected Cell Line

  Kaoru Miyazaki, Haruo Takaku, Makoto Umeda, Tuyosi Fujita, Weida Huang, Takashi Kimura, Jinpei Yamashita and Takekazu Horio

  Cancer Res August 1 1990 50 (15) 4522-4527;

  
  
• Articles

  Anticachectic Activity of 5′-Deoxy-5-fluorouridine in a Murine Tumor Cachexia Model, Colon 26 Adenocarcinoma

  Yutaka Tanaka, Hiroyuki Eda, Kaori Fujimoto, Takashi Tanaka, Tohru Ishikawa and Hideo Ishitsuka

  Cancer Res August 1 1990 50 (15) 4528-4532;

  
  
• Articles

  Effect of Sulfonation on the Cell and Tissue Distribution of the Photosensitizer Aluminum Phthalocyanine

  Wai-Shun Chan, John F. Marshall, Russel Svensen, Joanne Bedwell and Ian R. Hart

  Cancer Res August 1 1990 50 (15) 4533-4538;

  
  
• Articles

  In Vitro Biotransformations of Tetrachloro(d,l-trans)-1,2-diaminocyclohexaneplatinum(IV) (Tetraplatin) in Rat Plasma

  Stephen G. Chaney, Steven Wyrick and Gail Kaun Till

  Cancer Res August 1 1990 50 (15) 4539-4545;

  
  
• Articles

  Radioimmunotherapy of Human Colorectal Carcinoma Xenografts Using ⁹⁰Y-labeled Monoclonal Antibody CO17-1A Prepared by Two Bifunctional Chelate Techniques

  Yu-Chen C. Lee, Lee C. Washburn, Tan Tan H. Sun, Bill L. Byrd, James E. Crook, E. C. Holloway and Zenon Steplewski

  Cancer Res August 1 1990 50 (15) 4546-4551;

  
  
• Articles

  5-Hexyl-2′-deoxyuridine Blocks the Cytotoxic Effects of 5-Fluorodeoxyuridine or Deoxyadenosine in Leukemia L1210 Cells in Culture

  Joseph G. Cory, Mary C. Halley, Andras Jeney and Karoly Lapis

  Cancer Res August 1 1990 50 (15) 4552-4556;

  
  
• Articles

  Biosynthesis, Glycosylation and Intracellular Processing of the Neuroglandular Antigen, a Human Melanoma-associated Antigen

  Walter T. Dixon, Douglas J. Demetrick, Kunio Ohyama, Lydia K. J. Sikora and L. Martin Jerry

  Cancer Res August 1 1990 50 (15) 4557-4565;

  
  
• Articles

  Mutations Induced at the Hypoxanthine-Guanine Phosphoribosyltransferase Locus of Human T-Lymphoblasts by Perturbations of Purine Deoxyribonucleoside Triphosphate Pools

  Susan S. Mattano, Thomas D. Palella and Beverly S. Mitchell

  Cancer Res August 1 1990 50 (15) 4566-4571;

  
  
• Articles

  Synergistic Cytotoxicity Using 2′-Deoxy-5-azacytidine and Cisplatin or 4-Hydroperoxycyclophosphamide with Human Tumor Cells

  Philip Frost, James L. Abbruzzese, Barbara Hunt, Dorellyn Lee and Martha Ellis

  Cancer Res August 1 1990 50 (15) 4572-4577;

  
  
• Articles

  Characterization of Tumor Binding by the IC-21 Macrophage Cell Line

  Eric K. Crawford, Patricia S. Latham, Eliza M. Shah and Jeffrey D. Hasday

  Cancer Res August 1 1990 50 (15) 4578-4583;

  
  
• Articles

  Molecular Nature of in Vivo Mutations in Human Cells at the Autosomal HLA-A Locus

  Alexander A. Morley, Scott A. Grist, David R. Turner, Alexander Kutlaca and Greg Bennett

  Cancer Res August 1 1990 50 (15) 4584-4587;

  
  
• Articles

  Biological and Clinical Effects of the Combination of β- and γ-Interferons Administered as a 5-Day Continuous Infusion

  Joan H. Schiller, Barry Storer, Patricia L. Witt, Beth Nelson, Raymond R. Brown, Michel Horisberger, Sidney Grossberg and Ernest C. Borden

  Cancer Res August 1 1990 50 (15) 4588-4594;

  
  
• Articles

  Phase I and Pharmacokinetic Study of Brequinar Sodium (NSC 368390)

  Dennis A. Noe, Eric K. Rowinsky, Huey-Shin L. Shen, Barbara V. Clarke, Louise B. Grochow, William B. McGuire, Alexander Hantel, David B. Adams, Martin D. Abeloff, David S. Ettinger and Ross C. Donehower

  Cancer Res August 1 1990 50 (15) 4595-4599;

  
  
• Articles

  Exposure to Barbiturates in Utero and during Childhood and Risk of Intracranial and Spinal Cord Tumors

  Marilyn K. Goldhaber, Joseph V. Selby, Robert A. Hiatt and Charles P. Quesenberry

  Cancer Res August 1 1990 50 (15) 4600-4603;

  
  
• Articles

  Phosphorylation of Pyruvate Kinase Type K in Human Gliomas by a Cyclic Adenosine 5′-Monophosphate-independent Protein Kinase

  Paschal A. Oude Weernink, Gert Rijksen, Margreet C. M. van der Heijden and Gerard E. J. Staal

  Cancer Res August 1 1990 50 (15) 4604-4610;

  
  
• Articles

  Molecular Dosimetry of Polycyclic Aromatic Hydrocarbon Epoxides and Diol Epoxides via Hemoglobin Adducts

  Billy W. Day, Stephen Naylor, Liang-Shang Gan, Yousif Sahali, Thanh T. Nguyen, Paul L. Skipper, John S. Wishnok and Steven R. Tannenbaum

  Cancer Res August 1 1990 50 (15) 4611-4618;

  
  
• Articles

  Oxidative Stress Induces DNA Damage and Inhibits the Repair of DNA Lesions Induced by N-Acetoxy-2-acetylaminofluorene in Human Peripheral Mononuclear Leukocytes

  Ronald W. Pero, Marshall W. Anderson, Geraldine A. Doyle, Colleen H. Anna, Felix Romagna, Melvin Markowitz and Carl Bryngelsson

  Cancer Res August 1 1990 50 (15) 4619-4625;

  
  
• Articles

  Comparison of the Predictive Power of Different Prognostic Indices for Overall Survival in Patients with Advanced Ovarian Carcinoma

  Birthe Lund, Paula Williamson, Hans C. van Houwelingen and Jean P. Neijt

  Cancer Res August 1 1990 50 (15) 4626-4629;

  
  
• Articles

  Mechanism of Tumoricidal Activity of OK-432-specific L3T4⁺ Lyt2^- T-Cells

  Shoichi Ozaki, Toshihiko Suginoshita, Takeshi Watanabe and Hiroshi Obayashi

  Cancer Res August 1 1990 50 (15) 4630-4634;

  
  
• Articles

  Effect of Acrolein on Phosphoramide Mustard-induced Sister Chromatid Exchanges in Cultured Human Lymphocytes

  James L. Wilmer, Gregory L. Erexson and Andrew D. Kligerman

  Cancer Res August 1 1990 50 (15) 4635-4638;

  
  
• Articles

  Differing Specificities for 4-Aminofolate Analogues of Folylpolyglutamyl Synthetase from Tumors and Proliferative Intestinal Epithelium of the Mouse with Significance for Selective Antitumor Action

  B. G. Rumberger, J. R. Barrueco and F. M. Sirotnak

  Cancer Res August 1 1990 50 (15) 4639-4643;

  
  
• Articles

  In Vivo Inhibition of the Pyrimidine de Novo Enzyme Dihydroorotic Acid Dehydrogenase by Brequinar Sodium (DUP-785; NSC 368390) in Mice and Patients

  G. J. Peters, G. Schwartsmann, J. C. Nadal, E. J. Laurensse, C. J. van Groeningen, W. J. F. van der Vijgh and H. M. Pinedo

  Cancer Res August 1 1990 50 (15) 4644-4649;

  
  
• Articles

  Mechanism of 12-O-Tetradecanoylphorbol-13-acetate Enhanced Metabolism of Arachidonic Acid in Dog Urothelial Cells

  Terry V. Zenser, Thomas E. Eling, Zofia M. Duniec, Yun-Hua Huang Wong and Bernard B. Davis

  Cancer Res August 1 1990 50 (15) 4650-4655;

  
  
• Articles

  Biosynthesis and Glycosylation of the Carcinoma-associated Antigen Recognized by Monoclonal Antibody KS1/4

  Philip D. Fernsten, Katherine W. Pekny, Ralph A. Reisfeld and Leslie E. Walker

  Cancer Res August 1 1990 50 (15) 4656-4663;

  
  
• Articles

  Classifying Clinical Severity to Help Solve Problems of Stage Migration in Nonconcurrent Comparisons of Lung Cancer Therapy

  David G. Pfister, Carolyn K. Wells, Charles K. Chan and Alvan R. Feinstein

  Cancer Res August 1 1990 50 (15) 4664-4669;

  
  
• Articles

  Oral Contraceptive Use, Human Papillomavirus Infection, and Risk of Early Cytological Abnormalities of the Cervix

  Bryan P. Negrini, Mark H. Schiffman, Robert J. Kurman, Willard Barnes, Linda Lannom, Karen Malley, Louise A. Brinton, Gregorio Delgado, Sidney Jones, Jean-Gilles Tchabo and Wayne D. Lancaster

  Cancer Res August 1 1990 50 (15) 4670-4675;

  
  
• Articles

  Inhibition of Cancer Cell Urokinase Plasminogen Activator by Its Specific Inhibitor PAI-2 and Subsequent Effects on Extracellular Matrix Degradation

  Mark S. Baker, Pamela Bleakley, Graeme C. Woodrow and William F. Doe

  Cancer Res August 1 1990 50 (15) 4676-4684;

  
  
• Articles

  Comparative Metabolism of N′-Nitrosonornicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Cultured F344 Rat Oral Tissue and Esophagus

  Sharon E. Murphy, Rachel Heiblum and Neil Trushin

  Cancer Res August 1 1990 50 (15) 4685-4691;

  
  
• Articles

  Decreased NADPH:Cytochrome P-450 Reductase Activity and Impaired Drug Activation in a Mammalian Cell Line Resistant to Mitomycin C under Aerobic but not Hypoxic Conditions

  Paul R. Hoban, Michael I. Walton, Craig N. Robson, Judith Godden, Ian J. Stratford, Paul Workman, Adrian L. Harris and Ian D. Hickson

  Cancer Res August 1 1990 50 (15) 4692-4697;

  
  
• Articles

  3′-Deamino-3′-morpholino-13-deoxo-10-hydroxycarminomycin Conquers Multidrug Resistance by Rapid Influx following Higher Frequency of Formation of DNA Single- and Double-Strand Breaks

  Naoya Horichi, Haim Tapiero, Yoshikazu Sugimoto, Masami Bungo, Masahiko Nishiyama, Alain Fourcade, Theodore J. Lampidis, Kazuo Kasahara, Yasutsuna Sasaki, Terumi Takahashi and Nagahiro Saijo

  Cancer Res August 1 1990 50 (15) 4698-4701;

  
  
• Articles

  Plasma α-l-Fucosidase Activity and the Risk of Borderline Epithelial Ovarian Tumors

  Bernard L. Harlow, Noel S. Weiss and Eric H. Holmes

  Cancer Res August 1 1990 50 (15) 4702-4703;

  
  
• Articles

  Effect of Osmotic Pressure on Uptake of Chemotherapeutic Agents by Carcinoma Cells

  Robert L. Stephen, Jeanne M. Novak, Elizabeth M. Jensen, Carl Kablitz and Saundra S. Buys

  Cancer Res August 1 1990 50 (15) 4704-4708;

  
  
• Articles

  Potentiation of Interleukin 1α Mediated Antitumor Effects by Ketoconazole

  Paul G. Braunschweiger, Nirmal Kumar, Ioannis Constantinidis, Janna P. Wehrle, Jerry D. Glickson, Candace S. Johnson and Philip Furmanski

  Cancer Res August 1 1990 50 (15) 4709-4717;

  
  
• Articles

  Pharmacokinetics, Tissue Distribution, and Cell Localization of [³⁵S]Methionine-labeled Recombinant Human and Murine α Interferons in Mice

  Terrance G. Johns, Julie A. Kerry, Barry A. J. Veitch, Ian R. Mackay, Peter J. Tutton, Martin J. Tymms, Brian F. Cheetham, Paul J. Hertzog and Anthony W. Linnane

  Cancer Res August 1 1990 50 (15) 4718-4723;

  
  
• Articles

  Neoplastic Transformation of a Human Colonic Epithelial Cell Line: In Vitro Evidence for the Adenoma to Carcinoma Sequence

  Ann C. Williams, Sara J. Harper and Christos Paraskeva

  Cancer Res August 1 1990 50 (15) 4724-4730;

  
  
• Articles

  Gastric Precancerous Process in a High Risk Population: Cross-sectional Studies

  Pelayo Correa, William Haenszel, Carlos Cuello, Diego Zavala, Elizabeth Fontham, Guillermo Zarama, Steven Tannenbaum, Tito Collazos and Bernardo Ruiz

  Cancer Res August 1 1990 50 (15) 4731-4736;

  
  
• Articles

  Gastric Precancerous Process in a High Risk Population: Cohort Follow-up

  Pelayo Correa, William Haenszel, Carlos Cuello, Diego Zavala, Elizabeth Fontham, Guillermo Zarama, Steven Tannenbaum, Tito Collazos and Bernardo Ruiz

  Cancer Res August 1 1990 50 (15) 4737-4740;

  
  
• Articles

  Identification of Epidermal Cell Subpopulations with Increased Ornithine Decarboxylase Activity following Treatment of Murine Epidermis with 12-O-Tetradecanoylphorbol-13-acetate

  Fredika M. Robertson, Susan K. Gilmour, Alan H. Conney, Mon-Tuan Huang, Andrew J. Beavis, Jeffrey D. Laskin, Oili A. Hietala and Thomas G. O'Brien

  Cancer Res August 1 1990 50 (15) 4741-4746;

  
  
• Articles

  Influence of Male Genital Tract Mesenchymes on Differentiation of Dunning Prostatic Adenocarcinoma

  Norio Hayashi, Gerald R. Cunha and Y. C. Wong

  Cancer Res August 1 1990 50 (15) 4747-4754;

  
  
• Articles

  Identification and Characterization of a Rat Hepatic Oncofetal Membrane Glycoprotein

  Ronald A. Faris, Kerry D. McEntire, Nancy L. Thompson and Douglas C. Hixson

  Cancer Res August 1 1990 50 (15) 4755-4763;

  
  
• Articles

  Immune Abnormalities in Avian Erythroblastosis Virus-infected Chickens

  Arundhati Rao, Kimberly Kline and Bob G. Sanders

  Cancer Res August 1 1990 50 (15) 4764-4770;

  
  
• Articles

  Interleukin 1-induced Augmentation of Experimental Metastases from a Human Melanoma in Nude Mice

  Raffaella Giavazzi, Angela Garofalo, Maria Rosa Bani, Mauro Abbate, Pietro Ghezzi, Diana Boraschi, Alberto Mantovani and Elisabetta Dejana

  Cancer Res August 1 1990 50 (15) 4771-4775;

  
  
• Articles

  DNA Synthesis by L929 Cells following Doxorubicin Exposure

  Karl W. Lanks and John M. Lehman

  Cancer Res August 1 1990 50 (15) 4776-4778;

  
  
• Articles

  EJ/ras Neoplastic Transformation of Simian Virus 40-immortalized Human Uroepithelial Cells: A Rare Event

  Brian J. Christian, Chinghai Kao, Shi-Qi Wu, Lorraine F. Meisner and Catherine A. Reznikoff

  Cancer Res August 1 1990 50 (15) 4779-4786;

  
  
• Articles

  Multifocal Vascular Tumors in Fowl Induced by a Newly Isolated Retrovirus

  Dov Soffer, Nitzan Resnick-Roguel, Amiram Eldor and Moshe Kotler

  Cancer Res August 1 1990 50 (15) 4787-4793;

  
  
• Articles

  Development of an in Vitro Analogue of Initiated Mouse Epidermis to Study Tumor Promoters and Antipromoters

  Henry Hennings, Victor A. Robinson, Delores M. Michael, George R. Pettit, Reinhard Jung and Stuart H. Yuspa

  Cancer Res August 1 1990 50 (15) 4794-4800;

  
  
• Articles

  Analysis of Human Tumor Associated Thomsen-Friedenreich Antigen

  John Samuel, Antoine A. Noujaim, Grant D. MacLean, Mavanur R. Suresh and B. Michael Longenecker

  Cancer Res August 1 1990 50 (15) 4801-4808;

  
  
• Articles

  Expression of Hepatocyte and Oval Cell Antigens in Hepatocellular Carcinomas Produced by Oncogene-transfected Liver Epithelial Cells

  Michele Goyette, Ronald Faris, Lundy Braun, Douglas Hixson and Nelson Fausto

  Cancer Res August 1 1990 50 (15) 4809-4817;

  
  
• Articles

  Activation of K-ras by Codon 13 Mutations in C57BL/6 × C3H F₁ Mouse Tumors Induced by Exposure to 1,3-Butadiene

  Tamra Goodrow, Steven Reynolds, Robert Maronpot and Marshall Anderson

  Cancer Res August 1 1990 50 (15) 4818-4823;

  
  
• Articles

  Announcements

  Cancer Res August 1 1990 50 (15) 4824-4825;

  
  
• Errata

  Basic Fibroblast Growth Factor-like Activity and Receptors Are Expressed in a Human Glioma Cell Line

  Cancer Res August 1 1990 50 (15) 4825-4825;