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Basic Sciences

ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth in Vitro and in Vivo: A New Agent for Clinical Study

Ann L. Jackman, Gordon A. Taylor, William Gibson, Rosemary Kimbell, Melody Brown, A. Hilary Calvert, Ian R. Judson and Leslie R. Hughes
Ann L. Jackman
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Gordon A. Taylor
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William Gibson
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Rosemary Kimbell
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Melody Brown
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A. Hilary Calvert
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Ian R. Judson
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Leslie R. Hughes
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DOI:  Published October 1991
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Article Information

Volume 51, Issue 20, pp. 5579-5586

PubMed 
1913676

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received April 25, 1991
  • Accepted August 8, 1991
  • Published first October 1, 1991.

Copyright & Usage 
©1991 American Association for Cancer Research.

Author Information

  1. Ann L. Jackman2,
  2. Gordon A. Taylor3,
  3. William Gibson,
  4. Rosemary Kimbell,
  5. Melody Brown,
  6. A. Hilary Calvert3,
  7. Ian R. Judson, and
  8. Leslie R. Hughes
  1. Drug Development Section, Institute of Cancer Research, 15, Cotswold Road, Belmont, Sutton, Surrey, SM2 5PX [A. L. J., G. A. T., W. G., R. K., M. B., A. H. C., I. R. J.], and ICI Pharmaceuticals, Mereside, Alderley Park, Macclesfield, SK10 4TG [L. R. H.], United Kingdom
  • ↵3 Present address: Cancer Research Unit, Medical School, University of Newcastle, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, United Kingdom.

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October 1991
Volume 51, Issue 20
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ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth in Vitro and in Vivo: A New Agent for Clinical Study
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ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth in Vitro and in Vivo: A New Agent for Clinical Study
Ann L. Jackman, Gordon A. Taylor, William Gibson, Rosemary Kimbell, Melody Brown, A. Hilary Calvert, Ian R. Judson and Leslie R. Hughes
Cancer Res October 15 1991 (51) (20) 5579-5586;

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ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth in Vitro and in Vivo: A New Agent for Clinical Study
Ann L. Jackman, Gordon A. Taylor, William Gibson, Rosemary Kimbell, Melody Brown, A. Hilary Calvert, Ian R. Judson and Leslie R. Hughes
Cancer Res October 15 1991 (51) (20) 5579-5586;
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