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Part II: Genetic and Environmental Determinants

Does Chronic Fatigue Syndrome Predispose to Non-Hodgkin's Lymphoma?

Paul H. Levine, Daniel Peterson, Faye L. McNamee, Karen O'Brien, Gloria Gridley, Mary Hagerty, Jane Brady, Thomas Fears, Martin Atherton and Robert Hoover
Paul H. Levine
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Daniel Peterson
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Faye L. McNamee
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Karen O'Brien
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Gloria Gridley
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Mary Hagerty
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Jane Brady
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Thomas Fears
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Martin Atherton
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Robert Hoover
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DOI:  Published October 1992
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Abstract

Chronic fatigue syndrome, an illness that frequently is associated with abnormalities of cellular immunity, has been reported anecdotally to be associated with an increased incidence of lymphoid hyperplasia and malignancy. This report describes an initial analysis of population-based cancer incidence data in Nevada, focusing on the patterns of non-Hodgkin's lymphoma prior to and subsequent to well described, documented outbreaks of chronic fatigue syndrome during 1984–1986. In a study of time trends in four age groups, the observed time trends were consistent with the national trends reported in the Surveillance, Epidemiology, and End Results Program. No statistically significant increase attributable to the chronic fatigue syndrome outbreak was identified at the state level. Additional studies are in progress analyzing the data at the county level, reviewing patterns in other malignancies, and continuing to monitor the cancer patterns over subsequent years.

Footnotes

  • ↵2 To whom requests for reprints should be addressed, at Executive Plaza North, Room 434, Bethesda, MD 20892.

    • ©1992 American Association for Cancer Research.
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    October 1992
    Volume 52, Issue 19 Supplement
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    Does Chronic Fatigue Syndrome Predispose to Non-Hodgkin's Lymphoma?
    Paul H. Levine, Daniel Peterson, Faye L. McNamee, Karen O'Brien, Gloria Gridley, Mary Hagerty, Jane Brady, Thomas Fears, Martin Atherton and Robert Hoover
    Cancer Res October 1 1992 (52) (19 Supplement) 5516s-5517s;

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    Does Chronic Fatigue Syndrome Predispose to Non-Hodgkin's Lymphoma?
    Paul H. Levine, Daniel Peterson, Faye L. McNamee, Karen O'Brien, Gloria Gridley, Mary Hagerty, Jane Brady, Thomas Fears, Martin Atherton and Robert Hoover
    Cancer Res October 1 1992 (52) (19 Supplement) 5516s-5517s;
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    Part II: Genetic and Environmental Determinants

    • Nutritional Factors and the Development of Non-Hodgkin's Lymphoma: A Review of the Evidence
    • Increasing Incidence of Non-Hodgkin's Lymphoma: Occupational and Environmental Factors
    • Comments on Occupational and Environmental Factors in the Origin of Non-Hodgkin's Lymphoma
    Show more Part II: Genetic and Environmental Determinants

    Articles

    • Nutritional Factors and the Development of Non-Hodgkin's Lymphoma: A Review of the Evidence
    • Increasing Incidence of Non-Hodgkin's Lymphoma: Occupational and Environmental Factors
    • Comments on Occupational and Environmental Factors in the Origin of Non-Hodgkin's Lymphoma
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