Table of Contents

Articles

• Advances in Brief

  Protective and Curative Potential of Vaccination with Interleukin-2-Gene-transfected Cells from a Spontaneous Mouse Mammary Adenocarcinoma

  Federica Cavallo, Francesco Di Pierro, Mirella Giovarelli, Alberto Gulino, Alessandra Vacca, Antonella Stoppacciaro, Marco Forni, Andrea Modesti and Guido Forni

  Cancer Res November 1 1993 53 (21) 5067-5070;

  
  
• Advances in Brief

  Cooperation between v-fos and v-ras^HA Induces Autonomous Papillomas in Transgenic Epidermis but not Malignant Conversion

  David A. Greenhalgh, Maria I. Quintanilla, Christine C. Orengo, Jennifer L. Barber, Joshua N. Eckhardt, Joseph A. Rothnagel and Dennis R. Roop

  Cancer Res November 1 1993 53 (21) 5071-5075;

  
  
• Advances in Brief

  Polymerase Chain Reaction Analysis of Parathyroid Hormone-related Protein Gene Expression in Breast Cancer Patients and Occurrence of Bone Metastases

  Zhor Bouizar, Frédérique Spyratos, Stéphanie Deytieux, Marie-Christine de Vernejoul and Annick Jullienne

  Cancer Res November 1 1993 53 (21) 5076-5078;

  
  
• Advances in Brief

  Coexistence of Somatic and Germ-Line Mutations of APC Gene in Desmoid Tumors from Patients with Familial Adenomatous Polyposis

  Michiko Miyaki, Motoko Konishi, Rei Kikuchi-Yanoshita, Masayuki Enomoto, Kiyoko Tanaka, Hiromi Takahashi, Masatoshi Muraoka, Takeo Mori, Fumio Konishi and Takeo Iwama

  Cancer Res November 1 1993 53 (21) 5079-5082;

  
  
• Advances in Brief

  Linkage Analysis of DRD2, a Marker Linked to the Ataxia-Telangiectasia Gene, in 64 Families with Premenopausal Bilateral Breast Cancer

  Victoria Cortessis, Sue Ingles, Robert Millikan, Anh Diep, Richard A. Gatti, Lesley Richardson, W. Douglas Thompson, Annlia Paganini-Hill, Robert S. Sparkes and Robert W. Haile

  Cancer Res November 1 1993 53 (21) 5083-5086;

  
  
• Advances in Brief

  Genetic Instability in Pancreatic Cancer and Poorly Differentiated Type of Gastric Cancer

  Hye-Jung Han, Akio Yanagisawa, Yo Kato, Jae-Gahb Park and Yusuke Nakamura

  Cancer Res November 1 1993 53 (21) 5087-5089;

  
  
• Advances in Brief

  High Affinity Binding Sites for Gastrin Releasing Peptide on Human Gastric Cancer and Ménétrier's Mucosa

  Shaun R. Preston, Linda F. Woodhouse, Steven Jones-Blackett, Judy I. Wyatt and John N. Primrose

  Cancer Res November 1 1993 53 (21) 5090-5092;

  
  
• Advances in Brief

  Evidence for Two Bladder Cancer Suppressor Loci on Human Chromosome 9

  J. Michael Ruppert, Kaori Tokino and David Sidransky

  Cancer Res November 1 1993 53 (21) 5093-5095;

  
  
• Advances in Brief

  Simultaneous Analysis of Cell Cycle Kinetics at Two Different DNA Ploidy Levels Based on DNA Content and Cyclin B Measurements

  Jianping Gong, Frank Traganos and Zbigniew Darzynkiewicz

  Cancer Res November 1 1993 53 (21) 5096-5099;

  
  
• Advances in Brief

  Genetic Instability of Microsatellites in Endometrial Carcinoma

  John I. Risinger, Andrew Berchuck, Matthew F. Kohler, Patrice Watson, Henry T. Lynch and Jeff Boyd

  Cancer Res November 1 1993 53 (21) 5100-5103;

  
  
• Advances in Brief

  Elevated Production of Active Oxygen in Bloom's Syndrome Cell Lines

  Thomas Nicotera, Kuldip Thusu and Paresh Dandona

  Cancer Res November 1 1993 53 (21) 5104-5107;

  
  
• Advances in Brief

  Fusion of PAX3 to a Member of the Forkhead Family of Transcription Factors in Human Alveolar Rhabdomyosarcoma

  David N. Shapiro, Jack E. Sublett, Baitao Li, James R. Downing and Clayton W. Naeve

  Cancer Res November 1 1993 53 (21) 5108-5112;

  
  
• Special Lecture

  Recent Advances in Head and Neck Cancer—Larynx Preservation and Cancer Chemoprevention: The Seventeenth Annual Richard and Hinda Rosenthal Foundation Award Lecture

  Waun Ki Hong, Scott M. Lippman and Gregory T. Wolf

  Cancer Res November 1 1993 53 (21) 5113-5120;

  
  
• Biochemistry and Biophysics

  Involvement of Human Liver Cytochrome P450 3A in Vinblastine Metabolism: Drug Interactions

  Xin-Ru Zhou-Pan, Eric Sérée, Xiao-Jian Zhou, Michel Placidi, Patrick Maurel, Yves Barra and Roger Rahmani

  Cancer Res November 1 1993 53 (21) 5121-5126;

  
  
• Biochemistry and Biophysics

  Adducts of Mitomycin C and DNA in EMT6 Mouse Mammary Tumor Cells: Effects of Hypoxia and Dicumarol on Adduct Patterns

  Roland Bizanek, Dondapati Chowdary, Hitoshi Arai, Masaji Kasai, Christine S. Hughes, Alan C. Sartorelli, Sara Rockwell and Maria Tomasz

  Cancer Res November 1 1993 53 (21) 5127-5134;

  
  
• Biochemistry and Biophysics

  Cytochrome P-450-induced Cytotoxicity of Mitoxantrone by Formation of Electrophilic Intermediates

  Kersten Mewes, Joachim Blanz, Gerhard Ehninger, Rolf Gebhardt and Klaus-Peter Zeller

  Cancer Res November 1 1993 53 (21) 5135-5142;

  
  
• Biochemistry and Biophysics

  Purine Nucleotide Levels in Host Tissue of Ehrlich Ascites Tumor-bearing Mice in Different Growth Phases of the Tumor

  Werner G. Siems, Tilman Grune, Heike Schmidt, Yuri V. Tikhonov and Alexej M. Pimenov

  Cancer Res November 1 1993 53 (21) 5143-5147;

  
  
• Biochemistry and Biophysics

  Inhibitory Effects of α-Interferon on Epidermal Growth Factor-mediated Receptor-dependent Events

  E. N. Fish, J. Ghislain, J. Trogadis and J. K. Stevens

  Cancer Res November 1 1993 53 (21) 5148-5157;

  
  
• Carcinogenesis

  Migratory Pattern of Fetal Rat Brain Cells and Human Glioma Cells in the Adult Rat Brain

  Paal-Henning Pedersen, Kirsten Marienhagen, Sverre Mørk and Rolf Bjerkvig

  Cancer Res November 1 1993 53 (21) 5158-5165;

  
  
• Carcinogenesis

  Insulin-like Growth Factor II and WT1 Transcript Localization in Human Fetal Kidney and Wilms' Tumor

  Kankatsu Yun, Andrew E. Fidler, Michael R. Eccles and Anthony E. Reeve

  Cancer Res November 1 1993 53 (21) 5166-5171;

  
  
• Carcinogenesis

  Enhancement of Rat Urinary Bladder Tumorigenesis by Lipopolysaccharide-induced Inflammation

  Koji Kawai, Masashi Yamamoto, Shuji Kameyama, Hitoshi Kawamata, Alfred Rademaker and Ryoichi Oyasu

  Cancer Res November 1 1993 53 (21) 5172-5175;

  
  
• Clinical Investigations

  Phase I Trial of an Oral Immunomodulator and Interferon Inducer in Cancer Patients

  Patricia L. Witt, Paul S. Ritch, Douglas Reding, Timothy L. McAuliffe, Linda Westrick, Sidney E. Grossberg and Ernest C. Borden

  Cancer Res November 1 1993 53 (21) 5176-5180;

  
  
• Clinical Investigations

  Individualized Chemotherapy for Patients with Non-Small Cell Lung Cancer Determined by Prospective Identification of Neuroendocrine Markers and in Vitro Drug Sensitivity Testing

  Gail L. Shaw, Adi F. Gazdar, Ruby Phelps, R. Ilona Linnoila, Daniel C. Ihde, Bruce E. Johnson, Herbert K. Oie, Harvey I. Pass, Seth M. Steinberg, Bimal C. Ghosh, Thomas E. Walsh, John C. Nesbitt, James D. Cotelingam, John D. Minna and James L. Mulshine

  Cancer Res November 1 1993 53 (21) 5181-5187;

  
  
• Endocrinology

  Improved Prediction of Survival in Advanced Adenocarcinoma of the Ovary by Immunocytochemical Analysis and the Composition Adjusted Receptor Level of the Estrogen Receptor

  Dirk G. Kieback, Susan K. McCamant, Michael F. Press, E. Neely Atkinson, Harry S. Gallager, Creighton L. Edwards, Richard A. Hajek and Lovell A. Jones

  Cancer Res November 1 1993 53 (21) 5188-5192;

  
  
• Endocrinology

  Estrogen and Antiestrogen Modulation of MCF7 Human Breast Cancer Cell Proliferation Is Associated with Specific Alterations in Accumulation of Insulin-like Growth Factor-binding Proteins in Conditioned Media

  Susan E. Pratt and Michael N. Pollak

  Cancer Res November 1 1993 53 (21) 5193-5198;

  
  
• Endocrinology

  Hormone Regulation of Human Prostate in Organ Culture

  Marja T. Nevalainen, Pirkko L. Härkönen, Eeva M. Valve, Wu Ping, Martti Nurmi and Paula M. Martikainen

  Cancer Res November 1 1993 53 (21) 5199-5207;

  
  
• Endocrinology

  CCK_A and CCK_B Receptors Are Expressed in Small Cell Lung Cancer Lines and Mediate Ca²⁺ Mobilization and Clonal Growth

  Tariq Sethi, Thomas Herget, S. Vincent Wu, John H. Walsh and Enrique Rozengurt

  Cancer Res November 1 1993 53 (21) 5208-5213;

  
  
• Endocrinology

  Thymosin α1 Down-regulates the Growth of Human Non-Small Cell Lung Cancer Cells in Vitro and in Vivo

  Terry W. Moody, Mirela Fagarasan, Farah Zia, Mirjana Cesnjaj and Allan L. Goldstein

  Cancer Res November 1 1993 53 (21) 5214-5218;

  
  
• Experimental Therapeutics

  Resistance to Fluorodeoxyuridine-induced DNA Damage and Cytotoxicity Correlates with an Elevation of Deoxyuridine Triphosphatase Activity and Failure to Accumulate Deoxyuridine Triphosphate

  Christine E. Canman, Theodore S. Lawrence, Donna S. Shewach, Hsin-Yi Tang and Jonathan Maybaum

  Cancer Res November 1 1993 53 (21) 5219-5224;

  
  
• Experimental Therapeutics

  Cross-Resistance to Diverse Drugs Is Associated with Primary Cisplatin Resistance in Ovarian Cancer Cell Lines

  Kinya Hamaguchi, Andrew K. Godwin, Michiaki Yakushiji, Peter J. O'Dwyer, Robert F. Ozols and Thomas C. Hamilton

  Cancer Res November 1 1993 53 (21) 5225-5232;

  
  
• Experimental Therapeutics

  Angiogenesis Inhibitor TNP-470 (AGM-1470) Potently Inhibits the Tumor Growth of Hormone-independent Human Breast and Prostate Carcinoma Cell Lines

  Masuo Yamaoka, Toshihiro Yamamoto, Shuichi Ikeyama, Katsuichi Sudo and Takeshi Fujita

  Cancer Res November 1 1993 53 (21) 5233-5236;

  
  
• Experimental Therapeutics

  Protection from Adriamycin Cytotoxicity in L1210 Cells by Brefeldin A

  Paul J. Vichi and Thomas R. Tritton

  Cancer Res November 1 1993 53 (21) 5237-5243;

  
  
• Immunology

  Molecular Cloning of a Human Monoclonal Antibody Reactive to Ganglioside G_M3 Antigen on Human Cancers

  Dave S. B. Hoon, Yuan Wang, Lan Sze, Hidetoshi Kanda, Takeshi Watanabe, Sherie L. Morrison, Donald L. Morton and Reiko F. Irie

  Cancer Res November 1 1993 53 (21) 5244-5250;

  
  
• Molecular Biology and Genetics

  Neu Differentiation Factor (Heregulin) Induces Expression of Intercellular Adhesion Molecule 1: Implications for Mammary Tumors

  Sarah S. Bacus, Andrei V. Gudkov, Carolyn R. Zelnick, Dot Chin, Randi Stern, Ilana Stancovski, Elior Peles, Noa Ben-Baruch, Hannan Farbstein, Ruth Lupu, Duanzhi Wen, Michael Sela and Yosef Yarden

  Cancer Res November 1 1993 53 (21) 5251-5261;

  
  
• Molecular Biology and Genetics

  Development of Resistance to Hydroxyurea during Treatment of Human Myelogenous Leukemia K562 Cells with α-Difluoromethylornithine as a Result of Coamplification of Genes for Ornithine Decarboxylase and Ribonucleotide Reductase R2 Subunit

  Anders Ask, Lo Persson, Astrid Rehnholm, Lennart Frostesjö, Ingvar Holm and Olle Heby

  Cancer Res November 1 1993 53 (21) 5262-5268;

  
  
• Molecular Biology and Genetics

  Absence of p53 Gene Mutations in Primary Neuroblastomas

  Kyle Vogan, Mark Bernstein, Jean-Marie Leclerc, Linda Brisson, Josee Brossard, Garrett M. Brodeur, Jerry Pelletier and Philippe Gros

  Cancer Res November 1 1993 53 (21) 5269-5273;

  
  
• Molecular Biology and Genetics

  The “Bystander Effect”: Tumor Regression When a Fraction of the Tumor Mass Is Genetically Modified

  Scott M. Freeman, Camille N. Abboud, Katharine A. Whartenby, Charles H. Packman, David S. Koeplin, Frederick L. Moolten and George N. Abraham

  Cancer Res November 1 1993 53 (21) 5274-5283;

  
  
• Molecular Biology and Genetics

  Mutations of the p53 Gene Are Involved in Ewing's Sarcomas but not in Neuroblastomas

  Hiroaki Komuro, Yasuhide Hayashi, Machiko Kawamura, Kenshi Hayashi, Yasuhiko Kaneko, Shigehiko Kamoshita, Ryoji Hanada, Keiko Yamamoto, Teruaki Hongo, Masao Yamada and Yoshiaki Tsuchida

  Cancer Res November 1 1993 53 (21) 5284-5288;

  
  
• Tumor Biology

  Overexpression of Acidic and Basic Fibroblast Growth Factors in Human Pancreatic Cancer Correlates with Advanced Tumor Stage

  Yoichiro Yamanaka, Helmut Friess, Markus Buchler, Hans G. Beger, Eiji Uchida, Masahiko Onda, Michael S. Kobrin and Murray Korc

  Cancer Res November 1 1993 53 (21) 5289-5296;

  
  
• Tumor Biology

  Basic Fibroblast Growth Factor Secreted by an Animal Tumor Is Detectable in Urine

  Alexander D. Soutter, Mai Nguyen, Hiroyuki Watanabe and Judah Folkman

  Cancer Res November 1 1993 53 (21) 5297-5299;

  
  
• Tumor Biology

  Epidermal Growth Factor Receptor-mediated Autocrine and Paracrine Stimulation of Human Transitional Cell Carcinoma

  Martin E. Gleave, Jer-Tsong Hsieh, Hsi-Chin Wu, Sung-Joon Hong, Haiyen E. Zhau, Paul D. Guthrie and Leland W. K. Chung

  Cancer Res November 1 1993 53 (21) 5300-5307;

  
  
• Tumor Biology

  Tumor Cell Heme Uptake Induces Ferritin Synthesis Resulting in Altered Oxidant Sensitivity: Possible Role in Chemotherapy Efficacy

  Jaroslav Cermak, József Balla, Harry S. Jacob, György Balla, Helen Enright, Karl Nath and Gregory M. Vercellotti

  Cancer Res November 1 1993 53 (21) 5308-5313;

  
  
• Tumor Biology

  Apoptosis Induced in Burkitt's Lymphoma Cells via Gb3/CD77, a Glycolipid Antigen

  Marianne Mangeney, Clifford A. Lingwood, Samir Taga, Bernard Caillou, Thomas Tursz and Joëlle Wiels

  Cancer Res November 1 1993 53 (21) 5314-5319;

  
  
• Tumor Biology

  Coexistence of Aneuploid Subclones within a Myeloma Cell Line That Exhibits Clonal Immunoglobulin Gene Rearrangement: Clinical Implications

  Diane F. Jelinek, Gregory J. Ahmann, Philip R. Greipp, Syed M. Jalal, Jennifer J. Westendorf, Jerry A. Katzmann, Robert A. Kyle and John A. Lust

  Cancer Res November 1 1993 53 (21) 5320-5327;

  
  
• Virology

  Malignant Transformation of Cutaneous Lesions in Renal Allograft Patients: A Role for Human Papillomavirus?

  Karin J. Purdie, Connie J. Sexton, Charlotte M. Proby, Mary T. Glover, Anthony T. Williams, Jeremy N. Stables and Irene M. Leigh

  Cancer Res November 1 1993 53 (21) 5328-5333;

  
  
• Articles

  Announcements

  Cancer Res November 1 1993 53 (21) 5334-5336;