Table of Contents

Articles

• Advances in Brief

  Nuclear Signaling Induced by Ionizing Radiation Involves Colocalization of the Activated p56/p53^lyn Tyrosine Kinase with p34^cdc2

  Surender Kharbanda, Ahamed Saleem, Zhi-Min Yuan, Stine Kraeft, Ralph Weichselbaum, Lan Bo Chen and Donald Kufe

  Cancer Res August 15 1996 56 (16) 3617-3621;

  
  
• Advances in Brief

  Somatic and Germline Mutations of the BRCA2 Gene in Sporadic Ovarian Cancer

  Karen A. Foster, Patricia Harrington, Judith Kerr, Paul Russell, Richard A. DiCioccio, Ian V. Scott, Ian Jacobs, Georgia Chenevix-Trench, Bruce A. J. Ponder and Simon A. Gayther

  Cancer Res August 15 1996 56 (16) 3622-3625;

  
  
• Advances in Brief

  Hypersensitizing Effect of Pluronic L61 on Cytotoxic Activity, Transport, and Subcellular Distribution of Doxorubicin in Multiple Drug-resistant Cells

  Annie Venne, Shengmin Li, Rosemonde Mandeville, Alexander Kabanov and Valery Alakhov

  Cancer Res August 15 1996 56 (16) 3626-3629;

  
  
• Advances in Brief

  High Frequency of p16 (CDKN2/MTS-1/INK4A) Inactivation in Head and Neck Squamous Cell Carcinoma

  Andre L. Reed, Joseph Califano, Paul Cairns, William H. Westra, Richard M. Jones, Wayne Koch, Steven Ahrendt, Yolanda Eby, Duane Sewell, Homaira Nawroz, Jiri Bartek and David Sidransky

  Cancer Res August 15 1996 56 (16) 3630-3633;

  
  
• Advances in Brief

  Two Differentially Expressed Genes in Normal Human Prostate Tissue and in Carcinoma

  Fei-Lan Wang, Youbin Wang, Wai-Keung Wong, Yuan Liu, Frank John Addivinola, Peng Liang, Lan Bo Chen, Philip W. Kantoff and Arthur B. Pardee

  Cancer Res August 15 1996 56 (16) 3634-3637;

  
  
• Advances in Brief

  In Vitro Induction of Benzo(a)pyrene Diol Epoxide-DNA Adducts in Peripheral Lymphocytes as a Susceptibility Marker for Human Lung Cancer

  Donghui Li, Mianying Wang, Lie Cheng, Margaret R. Spitz, Walter N. Hittelman and Qingyi Wei

  Cancer Res August 15 1996 56 (16) 3638-3641;

  
  
• Advances in Brief

  Frequent Coordinated Overexpression of the MRP/GS-X Pump and γ-Glutamylcysteine Synthetase Genes in Human Colorectal Cancers

  M. Tien Kuo, Jia-Ju Bao, Steven A. Curley, Masahida Ikeguchi, Dennis A. Johnston and Toshihisa Ishikawa

  Cancer Res August 15 1996 56 (16) 3642-3644;

  
  
• Advances in Brief

  Transforming Growth Factor β1 Suppresses Genomic Instability Independent of a G₁ Arrest, p53, and Rb

  Adam B. Glick, Wendy C. Weinberg, I-Hui Wu, Wing Quan and Stuart H. Yuspa

  Cancer Res August 15 1996 56 (16) 3645-3650;

  
  
• Advances in Brief

  Pregnancy-dependent Growth of Mammary Tumors Is Associated with Overexpression of Insulin-like Growth Factor II

  Hung Huynh, Lesley Alpert and Michael Pollak

  Cancer Res August 15 1996 56 (16) 3651-3654;

  
  
• Advances in Brief

  Methylation of the Estrogen Receptor CpG Island in Lung Tumors Is Related to the Specific Type of Carcinogen Exposure

  Jean-Pierre J. Issa, Stephen B. Baylin and Steven A. Belinsky

  Cancer Res August 15 1996 56 (16) 3655-3658;

  
  
• Advances in Brief

  Separate Pathways for p53 Induction by Ionizing Radiation and N-(Phosphonoacetyl)-l-aspartate

  Chaw-Yuan M. Chen, Ingrid Hall, Timothy J. Lansing, Tona M. Gilmer, Thea D. Tlsty and Michael B. Kastan

  Cancer Res August 15 1996 56 (16) 3659-3662;

  
  
• Advances in Brief

  High Prevalence of the 999del5 Mutation in Icelandic Breast and Ovarian Cancer Patients

  Gudrun Johannesdottir, Julius Gudmundsson, Jon T. Bergthorsson, Adalgeir Arason, Bjarni A. Agnarsson, Gudny Eiriksdottir, Oskar T. Johannsson, Ake Borg, Sigurdur Ingvarsson, Douglas F. Easton, Valgardur Egilsson and Rosa Björk Barkardottir

  Cancer Res August 15 1996 56 (16) 3663-3665;

  
  
• Advances in Brief

  Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 225 Up-Regulates p27^KIP1 and Induces G₁ Arrest in Prostatic Cancer Cell Line DU145

  Ding Peng, Zhen Fan, Yang Lu, Tony DeBlasio, Howard Scher and John Mendelsohn

  Cancer Res August 15 1996 56 (16) 3666-3669;

  
  
• Biochemistry and Biophysics

  Vitamin B₆ and Cancer: Synthesis and Occurrence of Adenosine-N⁶-diethylthioether-N-pyridoximine-5′-phosphate, a Circulating Human Tumor Marker

  George P. Tryfiates, Peter M. Gannett, Ronald E. Bishop, Prem K. Shastri, Jason R. Ammons and James G. Arbogast

  Cancer Res August 15 1996 56 (16) 3670-3677;

  
  
• Biochemistry and Biophysics

  Busulfan-Glutathione Conjugation Catalyzed by Human Liver Cytosolic Glutathione S-Transferases

  John P. Gibbs, Maciej Czerwinski and John T. Slattery

  Cancer Res August 15 1996 56 (16) 3678-3681;

  
  
• Biochemistry and Biophysics

  Chaotic Oscillations in Cultured Cells: Rat Prostate Cancer

  Edwin M. Posadas, Stuart R. Criley and Donald S. Coffey

  Cancer Res August 15 1996 56 (16) 3682-3688;

  
  
• Biochemistry and Biophysics

  Identification and Properties of a Major Plasma Metabolite of Irinotecan (CPT-11) Isolated from the Plasma of Patients

  Laurent P. Rivory, Jean-François Riou, Marie-Christine Haaz, Serge Sable, Marc Vuilhorgne, Alain Commerçon, Susan M. Pond and Jacques Robert

  Cancer Res August 15 1996 56 (16) 3689-3694;

  
  
• Carcinogenesis

  Dose-dependent Differences in the Mutational Profiles of (-)-(1R,2S,3S,4R)-3,4-Dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene and Its Less Carcinogenic Enantiomer

  S-J. Caroline Wei, Richard L. Chang, Xiao X. Cui, Kathleen A. Merkler, Ching-Quo Wong, Haruhiko Yagi, Donald M. Jerina and Allan H. Conney

  Cancer Res August 15 1996 56 (16) 3695-3703;

  
  
• Carcinogenesis

  Phase II Enzyme Expression in Rat Liver in Response to the Antiestrogen Tamoxifen

  Emile F. Nuwaysir, Daniel A. Daggett, V. Craig Jordan and Henry C. Pitot

  Cancer Res August 15 1996 56 (16) 3704-3710;

  
  
• Carcinogenesis

  A New Process of Cancer Prevention Mediated through Inhibition of Tumor Necrosis Factor α Expression

  Masami Suganuma, Sachiko Okabe, Eisaburo Sueoka, Naoyuki Iida, Atsumasa Komori, Seong-Jin Kim and Hirota Fujiki

  Cancer Res August 15 1996 56 (16) 3711-3715;

  
  
• Carcinogenesis

  Two Dominant Host Resistance Genes to Pre-B Lymphoma in Wild-derived Inbred Mouse Strain MSM/Ms

  Abujiang Pataer, Toshiyuki Kamoto, Ling-Min Lu, Yoshihiro Yamada and Hiroshi Hiai

  Cancer Res August 15 1996 56 (16) 3716-3720;

  
  
• Carcinogenesis

  Increased Resistance to N,N′,N″-Triethylenethiophosphoramide (Thiotepa) in Cells Expressing the Escherichia coli Formamidopyrimidine-DNA Glycosylase

  R. D. Gill, C. Cussac, R. L. Souhami and F. Laval

  Cancer Res August 15 1996 56 (16) 3721-3724;

  
  
• Clinical Investigations

  Prognostic Significance of Germ Line Polymorphisms of the CYP1A1 and Glutathione S-Transferase Genes in Patients with Non-Small Cell Lung Cancer

  Isao Goto, Shuichi Yoneda, Mitsunobu Yamamoto and Kaname Kawajiri

  Cancer Res August 15 1996 56 (16) 3725-3730;

  
  
• Experimental Therapeutics

  Augmentation of Antitumor Immunity with Bacterial Superantigen, Staphylococcal Enterotoxin B-bound Tumor Cells

  Motomu Shimizu, Akira Yamamoto, Hideki Nakano and Akio Matsuzawa

  Cancer Res August 15 1996 56 (16) 3731-3736;

  
  
• Experimental Therapeutics

  Brain-derived Neurotrophic Factor Protects Neuroblastoma Cells from Vinblastine Toxicity

  Stefania Scala, Katja Wosikowski, Paraskevi Giannakakou, Paola Valle, June L. Biedler, Barbara A. Spengler, Enrico Lucarelli, Susan E. Bates and Carol J. Thiele

  Cancer Res August 15 1996 56 (16) 3737-3742;

  
  
• Experimental Therapeutics

  Doxorubicin Encapsulated in Sterically Stabilized Liposomes Is Superior to Free Drug or Drug-containing Conventional Liposomes at Suppressing Growth and Metastases of Human Lung Tumor Xenografts

  Takashi Sakakibara, Fang-An Chen, Hisashi Kida, Katsuyuki Kunieda, Rosa E. Cuenca, F. J. Martin and Richard B. Bankert

  Cancer Res August 15 1996 56 (16) 3743-3746;

  
  
• Experimental Therapeutics

  Up-Regulation of Vascular Endothelial Growth Factor Production by Iron Chelators

  Laurens V. Beerepoot, David T. Shima, Masatoshi Kuroki, Kiang-Teck Yeo and Emile E. Voest

  Cancer Res August 15 1996 56 (16) 3747-3751;

  
  
• Experimental Therapeutics

  Involvement of β-Glucuronidase in Intestinal Microflora in the Intestinal Toxicity of the Antitumor Camptothecin Derivative Irinotecan Hydrochloride (CPT-11) in Rats

  Kiyoshi Takasuna, Takehiro Hagiwara, Masaaki Hirohashi, Michiyuki Kato, Mamoru Nomura, Eiichi Nagai, Tsuyoshi Yokoi and Tetsuya Kamataki

  Cancer Res August 15 1996 56 (16) 3752-3757;

  
  
• Experimental Therapeutics

  Combination Suicide and Cytokine Gene Therapy for Hepatic Metastases of Colon Carcinoma: Sustained Antitumor Immunity Prolongs Animal Survival

  Shu-Hsia Chen, Ken-ichiro Kosai, Bisong Xu, Khiem Pham-Nguyen, Charles Contant, Milton J. Finegold and Savio L. C. Woo

  Cancer Res August 15 1996 56 (16) 3758-3762;

  
  
• Immunology

  Human Dendritic Cells Genetically Engineered to Express High Levels of the Human Epithelial Tumor Antigen Mucin (MUC-1)

  Robert A. Henderson, Maya T. Nimgaonkar, Simon C. Watkins, Paul D. Robbins, Edward D. Ball and Olivera J. Finn

  Cancer Res August 15 1996 56 (16) 3763-3770;

  
  
• Immunology

  Physiologically Based Kinetic Model of Effector Cell Biodistribution in Mammals: Implications for Adoptive Immunotherapy

  Hui Zhu, Robert J. Melder, Laurence T. Baxter and Rakesh K. Jain

  Cancer Res August 15 1996 56 (16) 3771-3781;

  
  
• Immunology

  Protective Antitumor Immunity Induced by Immunization with Completely Allogeneic Tumor Cells

  René E. M. Toes, Ria J. J. Blom, Ellen van der Voort, Rienk Offringa, Cornelis J. M. Melief and W. M. Kast

  Cancer Res August 15 1996 56 (16) 3782-3787;

  
  
• Immunology

  L-Lysine Effectively Blocks Renal Uptake of ¹²⁵I- or ^99mTc-labeled Anti-Tac Disulfide-stabilized Fv Fragment

  Hisataka Kobayashi, Tae M. Yoo, In S. Kim, Meyoung-Kon Kim, Nhat Le, Keith O. Webber, Ira Pastan, Chang H. Paik, William C. Eckelman and Jorge A. Carrasquillo

  Cancer Res August 15 1996 56 (16) 3788-3795;

  
  
• Immunology

  Selective Inhibition of Telomerase Activity during Terminal Differentiation of Immortal Cell Lines

  Leslie J. Bestilny, Christopher B. Brown, Yutaka Miura, Laurie D. Robertson and Karl T. Riabowol

  Cancer Res August 15 1996 56 (16) 3796-3802;

  
  
• Immunology

  Mapping of Chromosomal Imbalances in Pancreatic Carcinoma by Comparative Genomic Hybridization

  Sabina Solinas-Toldo, Christine Wallrapp, Friedericke Müller-Pillasch, Martin Bentz, Thomas Gress and Peter Lichter

  Cancer Res August 15 1996 56 (16) 3803-3807;

  
  
• Immunology

  Chromosome 7q Allelic Losses in Pancreatic Carcinoma

  Alberto Achille, Maria O. Biasi, Giuseppe Zamboni, Giuseppe Bogina, Alba R. Magalini, Paolo Pederzoli, Manuel Perucho and Aldo Scarpa

  Cancer Res August 15 1996 56 (16) 3808-3813;

  
  
• Immunology

  An Uncertain Role for p53 Gene Alterations in Human Prostate Cancers

  James D. Brooks, G. Steven Bova, Charles M. Ewing, Steven Piantadosi, Bob S. Carter, John C. Robinson, Jonathan I. Epstein and William B. Isaacs

  Cancer Res August 15 1996 56 (16) 3814-3822;

  
  
• Tumor Biology

  Quantitative Estimation of Epidermal Growth Factor Receptor and c-erbB-2 in Human Breast Cancer

  Kevin W. Robertson, Jonathan R. Reeves, Gerard Smith, W. Nicol Keith, Bradford W. Ozanne, Timothy G. Cooke and Peter D. Stanton

  Cancer Res August 15 1996 56 (16) 3823-3830;

  
  
• Tumor Biology

  Increased Expression of the Insulin-like Growth Factor I (IGF-I) Receptor Gene in Hepatocellular Carcinoma Cell Lines: Implications of IGF-I Receptor Gene Activation by Hepatitis B Virus X Gene Product

  Sun-Ok Kim, Jae-Gahb Park and Young Ik Lee

  Cancer Res August 15 1996 56 (16) 3831-3836;

  
  
• Tumor Biology

  Identification of Novel Regions of Deletion in Familial Wilms' Tumor by Comparative Genomic Hybridization

  Rachel A. Altura, Marcus Valentine, Hao Li, James M. Boyett, Patricia Shearer, Paul Grundy, David N. Shapiro and A. Thomas Look

  Cancer Res August 15 1996 56 (16) 3837-3841;

  
  
• Tumor Biology

  Spontaneous Intestinal Carcinomas and Skin Neoplasms in Msh2-deficient Mice

  Armin H. Reitmair, Mark Redston, Jian Chun Cai, Tony C.Y. Chuang, Matthew Bjerknes, Hazel Cheng, Kazy Hay, Steven Gallinger, Bharati Bapat and Tak W. Mak

  Cancer Res August 15 1996 56 (16) 3842-3849;

  
  
• Articles

  Announcements

  Cancer Res August 15 1996 56 (16) 3850-3853;

  
  
• Articles

  Correction

  Alphonse Taghian, Wilfried Budach, Anthony Zietman, Jill Freeman, Danielle Gioioso, Wlodzimierz Ruka and Herman D. Suit

  Cancer Res August 15 1996 56 (16) 3853-3853;