Table of Contents

Articles

• Advances in Brief

  Expression of Cyclooxygenase-2 in Human Lung Carcinoma

  Henrik Wolff, Kirsi Saukkonen, Sisko Anttila, Antti Karjalainen, Harri Vainio and Ari Ristimäki

  Cancer Res November 15 1998 58 (22) 4997-5001;

  
  
• Advances in Brief

  The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G₁ Growth Arrest in Glioma Cells

  Frank B. Furnari, H-J. Su Huang and Webster K. Cavenee

  Cancer Res November 15 1998 58 (22) 5002-5008;

  
  
• Advances in Brief

  Gene Expression Profiling of Alveolar Rhabdomyosarcoma with cDNA Microarrays

  Javed Khan, Richard Simon, Michael Bittner, Yidong Chen, Stephen B. Leighton, Thomas Pohida, Paul D. Smith, Yuan Jiang, Gerald C. Gooden, Jeffrey M. Trent and Paul S. Meltzer

  Cancer Res November 15 1998 58 (22) 5009-5013;

  
  
• Advances in Brief

  Cloning of the Human Aflatoxin B₁-Aldehyde Reductase Gene at 1p35-1p36.1 in a Region Frequently Altered in Human Tumor Cells

  Christian Praml, Larissa Savelyeva, Patrizia Perri and Manfred Schwab

  Cancer Res November 15 1998 58 (22) 5014-5018;

  
  
• Advances in Brief

  Evidence of Cisplatin-induced Senescent-like Growth Arrest in Nasopharyngeal Carcinoma Cells

  Xianghong Wang, Stephen C. H. Wong, Jie Pan, S. W. Tsao, Kevin H. Y. Fung, Dora L. W. Kwong, Jonathan S. T. Sham and John M. Nicholls

  Cancer Res November 15 1998 58 (22) 5019-5022;

  
  
• Advances in Brief

  Refined Chromosomal Localization of the Mismatch Repair and Hereditary Nonpolyposis Colorectal Cancer Genes hMSH2 and hMSH6

  Christoph Schmutte, Rodica Catrinel Marinescu, Neal G. Copeland, Nancy A. Jenkins, Joan Overhauser and Richard Fishel

  Cancer Res November 15 1998 58 (22) 5023-5026;

  
  
• Advances in Brief

  Identification of a Human Gene Encoding a Homologue of Saccharomyces cerevisiae EXO1, an Exonuclease Implicated in Mismatch Repair and Recombination

  Daniel X. Tishkoff, Neelam S. Amin, Carrie S. Viars, Karen C. Arden and Richard D. Kolodner

  Cancer Res November 15 1998 58 (22) 5027-5031;

  
  
• Advances in Brief

  Loss of FHIT Function in Lung Cancer and Preinvasive Bronchial Lesions

  Gabriella Sozzi, Ugo Pastorino, Luisa Moiraghi, Elda Tagliabue, Francesco Pezzella, Cristina Ghirelli, Silvana Tornielli, Laura Sard, Kay Huebner, Marco A. Pierotti, Carlo M. Croce and Silvana Pilotti

  Cancer Res November 15 1998 58 (22) 5032-5037;

  
  
• Advances in Brief

  Association of Cytochrome P450 1B1 (CYP1B1) Polymorphism with Steroid Receptor Status in Breast Cancer

  L. Renee Bailey, Nady Roodi, William D. Dupont and Fritz F. Parl

  Cancer Res November 15 1998 58 (22) 5038-5041;

  
  
• Advances in Brief

  Comparative Genomic Hybridization Analysis of Chromosomal Alterations Induced by the Development of Resistance to Thymidylate Synthase Inhibitors

  Patrick H. Rooney, David A. J. Stevenson, Sharon Marsh, Patrick G. Johnston, Neva E. Haites, James Cassidy and Howard L. McLeod

  Cancer Res November 15 1998 58 (22) 5042-5045;

  
  
• Advances in Brief

  ETV6-NTRK3 Gene Fusions and Trisomy 11 Establish a Histogenetic Link between Mesoblastic Nephroma and Congenital Fibrosarcoma

  Stevan R. Knezevich, Mathew J. Garnett, Theodore J. Pysher, J. Bruce Beckwith, Paul E. Grundy and Poul H. B. Sorensen

  Cancer Res November 15 1998 58 (22) 5046-5048;

  
  
• Advances in Brief

  The COOH-terminal Region of pRb2/p130 Binds to Histone Deacetylase 1 (HDAC1), Enhancing Transcriptional Repression of the E2F-dependent Cyclin A Promoter

  Peter Stiegler, Antonio De Luca, Luigi Bagella and Antonio Giordano

  Cancer Res November 15 1998 58 (22) 5049-5052;

  
  
• Advances in Brief

  p21^WAF1/CIP1 Mutants Deficient in Inhibiting Cyclin-dependent Kinases (CDKs) Can Promote Assembly of Active Cyclin D/CDK4(6) Complexes in Human Tumor Cells

  Markus Welcker, Jiri Lukas, Michael Strauss and Jiri Bartek

  Cancer Res November 15 1998 58 (22) 5053-5056;

  
  
• Advances in Brief

  Nuclear but not Cytoplasmic Phospholipase C β₁ Inhibits Differentiation of Erythroleukemia Cells

  Alessandro Matteucci, Irene Faenza, R. Stewart Gilmour, Lucia Manzoli, Anna Maria Billi, Daniela Peruzzi, Alberto Bavelloni, Sue-Goo Rhee and Lucio Cocco

  Cancer Res November 15 1998 58 (22) 5057-5060;

  
  
• Advances in Brief

  The Potential Tumor Suppressor p73 Differentially Regulates Cellular p53 Target Genes

  Jianhui Zhu, Jieyuan Jiang, Wenjing Zhou and Xinbin Chen

  Cancer Res November 15 1998 58 (22) 5061-5065;

  
  
• Advances in Brief

  Naturally Processed Class II Epitope from the Tumor Antigen MUC1 Primes Human CD4⁺ T Cells

  Elizabeth M. Hiltbold, Pawel Ciborowski and Olivera J. Finn

  Cancer Res November 15 1998 58 (22) 5066-5070;

  
  
• Advances in Brief

  Inhibition of Apoptosis by Survivin Predicts Shorter Survival Rates in Colorectal Cancer

  Hiroshi Kawasaki, Dario C. Altieri, Cai-De Lu, Masao Toyoda, Toshiyuki Tenjo and Nobuhiko Tanigawa

  Cancer Res November 15 1998 58 (22) 5071-5074;

  
  
• Advances in Brief

  Functional Interactions of p53 with Poly(ADP-ribose) Polymerase (PARP) during Apoptosis following DNA Damage: Covalent Poly(ADP-ribosyl)ation of p53 by Exogenous PARP and Noncovalent Binding of p53 to the M_r 85,000 Proteolytic Fragment

  Sunitha R. Kumari, Hilda Mendoza-Alvarez and Rafael Alvarez-Gonzalez

  Cancer Res November 15 1998 58 (22) 5075-5078;

  
  
• Advances in Brief

  Characterization of Alkaline Phosphatase Genes Expressed in Seminoma by cDNA Cloning

  Atsuko Shigenari, Asako Ando, Tamami Baba, Tateki Yamamoto, Yoji Katsuoka and Hidetoshi Inoko

  Cancer Res November 15 1998 58 (22) 5079-5082;

  
  
• Biochemistry and Biophysics

  Lactate Turnover in Rat Glioma Measured by in Vivo Nuclear Magnetic Resonance Spectroscopy

  Melissa Terpstra, Rolf Gruetter, Wanda B. High, Marlene Mescher, Lance DelaBarre, Hellmut Merkle and Michael Garwood

  Cancer Res November 15 1998 58 (22) 5083-5088;

  
  
• Carcinogenesis

  Reversion of the Neoplastic Phenotype of Human Glioblastoma Cells by Connexin 43 (cx43)

  Ruo-Pan Huang, Yan Fan, Mohammad Z. Hossain, Ao Peng, Zi-Li Zeng and Alton L. Boynton

  Cancer Res November 15 1998 58 (22) 5089-5096;

  
  
• Carcinogenesis

  Harvey ras Results in a Higher Frequency of Mammary Carcinomas than Kirsten ras after Direct Retroviral Transfer into the Rat Mammary Gland

  Todd A. Thompson, Kwanghee Kim and Michael N. Gould

  Cancer Res November 15 1998 58 (22) 5097-5104;

  
  
• Endocrinology

  Testing the Gonadal Regression-Cytoprotection Hypothesis

  Bronwyn A. L. Crawford, Jenny A. Spaliviero, Julie M. Simpson and David J. Handelsman

  Cancer Res November 15 1998 58 (22) 5105-5109;

  
  
• Endocrinology

  Estrogen Receptor Expression Activates the Transcriptional and Growth-inhibitory Response to Retinoids without Enhanced Retinoic Acid Receptor α Expression

  Angelika Rosenauer, Clara Nervi, Kelly Davison, William W. Lamph, Sylvie Mader and Wilson H. Miller Jr.

  Cancer Res November 15 1998 58 (22) 5110-5116;

  
  
• Epidemiology and Prevention

  A Prospective Study of Physical Activity and Prostate Cancer in Male Health Professionals

  Edward Giovannucci, Michael Leitzmann, Donna Spiegelman, Eric B. Rimm, Graham A. Colditz, Meir J. Stampfer and Walter C. Willett

  Cancer Res November 15 1998 58 (22) 5117-5122;

  
  
• Epidemiology and Prevention

  NH₂-terminally Truncated HER-2/neu Protein: Relationship with Shedding of the Extracellular Domain and with Prognostic Factors in Breast Cancer

  Tracy A. Christianson, Joni K. Doherty, Yuzhong J. Lin, Elizabeth E. Ramsey, Ron Holmes, Edward J. Keenan and Gail M. Clinton

  Cancer Res November 15 1998 58 (22) 5123-5129;

  
  
• Epidemiology and Prevention

  Characterization of Vincristine Transport by the M_r 190,000 Multidrug Resistance Protein (MRP): Evidence for Cotransport with Reduced Glutathione

  Douglas W. Loe, Roger G. Deeley and Susan P. C. Cole

  Cancer Res November 15 1998 58 (22) 5130-5136;

  
  
• Epidemiology and Prevention

  Biliary Excretion Mechanism of CPT-11 and Its Metabolites in Humans: Involvement of Primary Active Transporters

  Xiao-Yan Chu, Yukio Kato, Kaoru Ueda, Hiroshi Suzuki, Kayoko Niinuma, Charles A. Tyson, Valorie Weizer, Jack E. Dabbs, Ritchie Froehlich, Carol E. Green and Yuichi Sugiyama

  Cancer Res November 15 1998 58 (22) 5137-5143;

  
  
• Immunology

  The Peptide Recognized by HLA-A68.2-restricted, Squamous Cell Carcinoma of the Lung-specific Cytotoxic T Lymphocytes Is Derived from a Mutated Elongation Factor 2 Gene

  Kevin T. Hogan, Dominic P. Eisinger, Samuel B. Cupp III, Kristen J. Lekstrom, Donna D. Deacon, Jeffrey Shabanowitz, Donald F. Hunt, Victor H. Engelhard, Craig L. Slingluff Jr. and Mark M. Ross

  Cancer Res November 15 1998 58 (22) 5144-5150;

  
  
• Immunology

  The Anti-MUC1 Monoclonal Antibody BCP8 Can Be Used to Isolate and Identify Putative Major Histocompatibility Complex Class I Associated Amino Acid Sequences

  Babita Agrawal, Mark A. Reddish, Brenda Christian, Anneke VanHeele, Leon Tang, R. Rao Koganty and B. Michael Longenecker

  Cancer Res November 15 1998 58 (22) 5151-5156;

  
  
• Molecular Biology and Genetics

  c-Met Autocrine Activation Induces Development of Malignant Melanoma and Acquisition of the Metastatic Phenotype

  Toshiyuki Otsuka, Hisashi Takayama, Richard Sharp, Giulia Celli, William J. LaRochelle, Donald P. Bottaro, Nelson Ellmore, Wilfred Vieira, Jennie W. Owens, Miriam Anver and Glenn Merlino

  Cancer Res November 15 1998 58 (22) 5157-5167;

  
  
• Molecular Biology and Genetics

  c-Myb Down-Regulation Is Associated with Human Colon Cell Differentiation, Apoptosis, and Decreased Bcl-2 Expression

  M. Anne Thompson, Mark A. Rosenthal, Sarah L. Ellis, Annabel J. Friend, Michelle I. Zorbas, Robert H. Whitehead and Robert G. Ramsay

  Cancer Res November 15 1998 58 (22) 5168-5175;

  
  
• Molecular Biology and Genetics

  Identification of a Brain-specific APC Homologue, APCL, and Its Interaction with β-Catenin

  Hidewaki Nakagawa, Yoji Murata, Kumiko Koyama, Asao Fujiyama, Yasuo Miyoshi, Morito Monden, Tetsu Akiyama and Yusuke Nakamura

  Cancer Res November 15 1998 58 (22) 5176-5181;

  
  
• Molecular Biology and Genetics

  Frequent Aberration of FHIT Gene Expression in Acute Leukemias

  Toshiki Iwai, Shouhei Yokota, Makoto Nakao, Naozo Nakazawa, Masafumi Taniwaki, Takayuki Kimura, Yoshiaki Sonoda, Hiroto Kaneko, Tsukasa Okuda, Hiroshi Azuma, Toshiaki Oka, Takeo Takeda, Arata Watanabe, Atsushi Kikuta, Keiko Asami, Isao Sekine, Takeji Matsushita, Takayoshi Tsuchiya, Junichi Mimaya, Shoichi Koizumi, Shigeru Ohta, Munenori Miyake, Yoichi Takaue, Asayuki Iwai, Kenichi Nishikawa, Kazuhiro Matsumoto, Kiyoshi Kawakami, Nobuyuki Hyakuna and Takeo Fujimoto

  Cancer Res November 15 1998 58 (22) 5182-5187;

  
  
• Molecular Biology and Genetics

  Failure to Complement Abnormal Phenotypes of Simian Virus 40-transformed Werner Syndrome Cells by Introduction of a Normal Human Chromosome 8

  Seiji Kodama, Genro Kashino, Keiji Suzuki, Toshihiro Takatsuji, Yutaka Okumura, Mitsuo Oshimura, Masami Watanabe and J. Carl Barrett

  Cancer Res November 15 1998 58 (22) 5188-5195;

  
  
• Molecular Biology and Genetics

  Nucleotide Excision Repair of Melphalan Monoadducts

  David F. Grant, Tadayoshi Bessho and Joyce T. Reardon

  Cancer Res November 15 1998 58 (22) 5196-5200;

  
  
• Molecular Biology and Genetics

  Identification and Characterization of Murine Caspase-14, a New Member of the Caspase Family

  Manzoor Ahmad, Srinivasa M. Srinivasula, Ramesh Hegde, Rula Mukattash, Teresa Fernandes-Alnemri and Emad S. Alnemri

  Cancer Res November 15 1998 58 (22) 5201-5205;

  
  
• Tumor Biology

  Distinct Roles of Osteopontin in Host Defense Activity and Tumor Survival during Squamous Cell Carcinoma Progression in Vivo

  Howard C. Crawford, Lynn M. Matrisian and Lucy Liaw

  Cancer Res November 15 1998 58 (22) 5206-5215;

  
  
• Tumor Biology

  X-Ray-induced P-selectin Localization to the Lumen of Tumor Blood Vessels

  Dennis E. Hallahan, Mary Jane Staba-Hogan, Subbu Virudachalam and Alexander Kolchinsky

  Cancer Res November 15 1998 58 (22) 5216-5220;

  
  
• Tumor Biology

  Role of the Plasminogen Activator and Matrix Metalloproteinase Systems in Epidermal Growth Factor- and Scatter Factor-stimulated Invasion of Carcinoma Cells

  Eben L. Rosenthal, Timothy M. Johnson, Edward D. Allen, Ingrid J. Apel, Antonello Punturieri and Stephen J. Weiss

  Cancer Res November 15 1998 58 (22) 5221-5230;

  
  
• Tumor Biology

  Inhibition of Murine Bladder Tumorigenesis by Soy Isoflavones via Alterations in the Cell Cycle, Apoptosis, and Angiogenesis

  Jin-Rong Zhou, Purna Mukherjee, Eric T. Gugger, Toshihide Tanaka, George L. Blackburn and Steven K. Clinton

  Cancer Res November 15 1998 58 (22) 5231-5238;

  
  
• Tumor Biology

  The Presence of a Constitutively Active Phosphoinositide 3-Kinase in Small Cell Lung Cancer Cells Mediates Anchorage-independent Proliferation via a Protein Kinase B and p70^s6k-dependent Pathway

  Sarah M. Moore, Robert C. Rintoul, Trevor R. Walker, Edwin R. Chilvers, Christopher Haslett and Tariq Sethi

  Cancer Res November 15 1998 58 (22) 5239-5247;

  
  
• Meeting Report

  A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer

  C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton, David Sidransky, James R. Eshleman, Randall W. Burt, Stephen J. Meltzer, Miguel A. Rodriguez-Bigas, Riccardo Fodde, G. Nadia Ranzani and Sudhir Srivastava

  Cancer Res November 15 1998 58 (22) 5248-5257;

  
  
• Articles

  Announcements

  Cancer Res November 15 1998 58 (22) 5258-5260;

  
  
• Articles

  Erratum

  Cancer Res November 15 1998 58 (22) 5260-5260;