Table of Contents

Advances in Brief

• Advances in Brief

  Selection for Androgen Receptor Mutations in Prostate Cancers Treated with Androgen Antagonist

  Mary-Ellen Taplin, Glenn J. Bubley, Yoo-Joung Ko, Eric J. Small, Melissa Upton, Barur Rajeshkumar and Steven P. Balk

  Cancer Res June 1 1999 59 (11) 2511-2515;

  
  
• Advances in Brief

  Role of the Alternative INK4A Proteins in Human Keratinocyte Senescence: Evidence for the Specific Inactivation of p16^INK4A upon Immortalization

  June Munro, Francesca J. Stott, Karen H. Vousden, Gordon Peters and E. Kenneth Parkinson

  Cancer Res June 1 1999 59 (11) 2516-2521;

  
  
• Advances in Brief

  Endogenous Apurinic/Apyrimidinic Sites in Genomic DNA of Mammalian Tissues

  Jun Nakamura and James A. Swenberg

  Cancer Res June 1 1999 59 (11) 2522-2526;

  
  
• Advances in Brief

  A New cis Element Is Involved in the HER2 Gene Overexpression in Human Breast Cancer Cells

  Madeleine Grooteclaes, Douglas Vernimmen, Serge Plaza, Françoise Pasleau, Didier Hodzic and Rosita Winkler-Gol

  Cancer Res June 1 1999 59 (11) 2527-2531;

  
  
• Advances in Brief

  Antifolate Resistance Mediated by the Multidrug Resistance Proteins MRP1 and MRP2

  Jan Hendrik Hooijberg, Henk J. Broxterman, Marcel Kool, Yehuda G. Assaraf, Godefridus J. Peters, Paul Noordhuis, Rik J. Scheper, Piet Borst, Herbert M. Pinedo and Gerrit Jansen

  Cancer Res June 1 1999 59 (11) 2532-2535;

  
  
• Advances in Brief

  Recombinant Virus Vaccination against “Self” Antigens UsingAnchor-fixed Immunogens

  Kari R. Irvine, Maria R. Parkhurst, Eliza P. Shulman, Janis P. Tupesis, Mary Custer, Christopher E. Touloukian, Paul F. Robbins, Alicia Gómez Yafal, Patricia Greenhalgh, Roger P. M. Sutmuller, Rienk Offringa, Steven A. Rosenberg and Nicholas P. Restifo

  Cancer Res June 1 1999 59 (11) 2536-2540;

  
  
• Advances in Brief

  Gain of Bcl-2 Is More Potent Than Bax Loss in Regulating Mammary Epithelial Cell Survival in Vivo

  Kristel Schorr, Minglin Li, Ud Bar-Peled, Albert Lewis, Alonso Heredia, Bernadette Lewis, C. Michael Knudson, Stanley J. Korsmeyer, Richard Jäger, Hans Weiher and Priscilla A. Furth

  Cancer Res June 1 1999 59 (11) 2541-2545;

  
  
• Advances in Brief

  Increased Level of Exon 12 Alternatively Spliced BRCA2 Transcripts in Tumor Breast Tissue Compared with Normal Tissue

  Ivan Bièche and Rosette Lidereau

  Cancer Res June 1 1999 59 (11) 2546-2550;

  
  
• Advances in Brief

  Regulation of Akt/PKB Activity, Cellular Growth, and Apoptosis in Prostate Carcinoma Cells by MMAC/PTEN

  Michael A. Davies, Dimpy Koul, Haninder Dhesi, Russell Berman, Timothy J. McDonnell, David McConkey, W. K. Alfred Yung and Peter A. Steck

  Cancer Res June 1 1999 59 (11) 2551-2556;

  
  
• Advances in Brief

  XRCC1 Polymorphisms: Effects on Aflatoxin B₁-DNA Adducts and Glycophorin A Variant Frequency

  Ruth M. Lunn, Ronald G. Langlois, Ling Ling Hsieh, Claudia L. Thompson and Douglas A. Bell

  Cancer Res June 1 1999 59 (11) 2557-2561;

  
  
• Advances in Brief

  p53 Directly Enhances Rejoining of DNA Double-Strand Breaks with Cohesive Ends in γ-Irradiated Mouse Fibroblasts

  Wei Tang, Henning Willers and Simon N. Powell

  Cancer Res June 1 1999 59 (11) 2562-2565;

  
  
• Advances in Brief

  Discovery and Initial Characterization of the Paullones, a Novel Class of Small-Molecule Inhibitors of Cyclin-dependent Kinases

  Daniel W. Zaharevitz, Rick Gussio, Maryse Leost, Adrian M. Senderowicz, Tyler Lahusen, Conrad Kunick, Laurent Meijer and Edward A. Sausville

  Cancer Res June 1 1999 59 (11) 2566-2569;

  
  
• Advances in Brief

  Identification and Characterization of Human MT5-MMP, a New Membrane-bound Activator of Progelatinase A Overexpressed in Brain Tumors

  Elena Llano, Alberto M. Pendás, José P. Freije, Atsuhisa Nakano, Vera Knäuper, Gillian Murphy and Carlos López-Otin

  Cancer Res June 1 1999 59 (11) 2570-2576;

  
  
• Advances in Brief

  Transduced p16^INK4a Peptides Inhibit Hypophosphorylation of the Retinoblastoma Protein and Cell Cycle Progression Prior to Activation of Cdk2 Complexes in Late G₁

  David R. Gius, Sergei A. Ezhevsky, Michelle Becker-Hapak, Hikaru Nagahara, Michael C. Wei and Steven F. Dowdy

  Cancer Res June 1 1999 59 (11) 2577-2580;