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Table of Contents

Perspectives in Cancer Research

  • Perspectives in Cancer Research
    On the Prevention and Therapy of Prostate Cancer by Androgen Administration
    Richmond T. Prehn
    Cancer Res September 1 1999 59 (17) 4161-4164;

Advances in Brief

  • Advances in Brief
    Mutational Analysis of the p63/p73L/p51/p40/CUSP/KET Gene in Human Cancer Cell Lines Using Intronic Primers
    Koichi Hagiwara, Mary G. McMenamin, Ko Miura and Curtis C. Harris
    Cancer Res September 1 1999 59 (17) 4165-4169;

  • Advances in Brief
    Alterations of the PPP1R3 Gene in Human Cancer
    Takashi Kohno, Satoshi Takakura, Tatsuya Yamada, Aikou Okamoto, Tadao Tanaka and Jun Yokota
    Cancer Res September 1 1999 59 (17) 4170-4174;

  • Advances in Brief
    Telomerase-negative Immortalized Human Cells Contain a Novel Type of Promyelocytic Leukemia (PML) Body
    Thomas R. Yeager, Axel A. Neumann, Anna Englezou, Lily I. Huschtscha, Jane R. Noble and Roger R. Reddel
    Cancer Res September 1 1999 59 (17) 4175-4179;

  • Advances in Brief
    Prostate-localized and Androgen-regulated Expression of the Membrane-bound Serine Protease TMPRSS2
    Biaoyang Lin, Camari Ferguson, James T. White, Shunyou Wang, Robert Vessella, Lawrence D. True, Leroy Hood and Peter S. Nelson
    Cancer Res September 1 1999 59 (17) 4180-4184;

  • Advances in Brief
    Ultraviolet Radiation Induces p16CDKN2A Expression in Human Skin
    Sandra Pavey, Sinead Conroy, Terry Russell and Brian Gabrielli
    Cancer Res September 1 1999 59 (17) 4185-4189;

  • Advances in Brief
    Expression of the Steroid Receptor RNA Activator in Human Breast Tumors
    Etienne Leygue, Helmut Dotzlaw, Peter H. Watson and Leigh C. Murphy
    Cancer Res September 1 1999 59 (17) 4190-4193;

  • Advances in Brief
    Metallothionein Is Overexpressed by Hamster Fibroblasts Selected for Growth in 15 pm Folinic Acid and Provides a Growth Advantage in Low Folate
    Wei-Yong Zhu and Peter W. Melera
    Cancer Res September 1 1999 59 (17) 4194-4199;

  • Advances in Brief
    The Addition of Adenovirus Type 5 Region E3 Enables Calydon Virus 787 to Eliminate Distant Prostate Tumor Xenografts
    De-Chao Yu, Yu Chen, Monica Seng, Jeanette Dilley and Daniel R. Henderson
    Cancer Res September 1 1999 59 (17) 4200-4203;

  • Advances in Brief
    Overexpression of Ribonucleotide Reductase as a Mechanism of Resistance to 2,2-Difluorodeoxycytidine in the Human KB Cancer Cell Line
    Yih-Gang Goan, Bingsen Zhou, Edward Hu, Shu Mi and Yun Yen
    Cancer Res September 1 1999 59 (17) 4204-4207;

  • Advances in Brief
    Activation of the PI3′K-AKT Pathway Masks the Proapoptotic Effects of Farnesyltransferase Inhibitors
    Wei Du, Aixue Liu and George C. Prendergast
    Cancer Res September 1 1999 59 (17) 4208-4212;

  • Advances in Brief
    Frequent Frameshift Mutations of the TCF-4 Gene in Colorectal Cancers with Microsatellite Instability
    Alex Duval, Jacqueline Gayet, Xiao-Ping Zhou, Barry Iacopetta, Gilles Thomas and Richard Hamelin
    Cancer Res September 1 1999 59 (17) 4213-4215;

  • Advances in Brief
    Four New Colon Cancer Susceptibility Loci, Scc6 to Scc9 in the Mouse
    Tom van Wezel, Claudia A. L. Ruivenkamp, Alphons P. M. Stassen, Corina J. A. Moen and Peter Demant
    Cancer Res September 1 1999 59 (17) 4216-4218;

  • Advances in Brief
    Heat Shock Cognate 70 Mutations in Sporadic Breast Carcinoma
    Christopher J. Bakkenist, John Koreth, Cory S. M. Williams, Nicholas C. A. Hunt and James O. McGee
    Cancer Res September 1 1999 59 (17) 4219-4221;

  • Advances in Brief
    Absence of Genetic Alteration at Codon 531 of the Human c-src Gene in 479 Advanced Colorectal Cancers from Japanese and Caucasian Patients
    Yataro Daigo, Yoichi Furukawa, Teru Kawasoe, Hideyuki Ishiguro, Manabu Fujita, Sachiko Sugai, Shoji Nakamori, Gerrit-Jan Liefers, Rob A. E. M. Tollenaar, Cornelis J. H. van de Velde and Yusuke Nakamura
    Cancer Res September 1 1999 59 (17) 4222-4224;

  • Advances in Brief
    Correlation between Expression of the Matrix Metalloproteinase-1 Gene in Ovarian Cancers and an Insertion/Deletion Polymorphism in Its Promoter Region
    Yasunobu Kanamori, Mieko Matsushima, Takeo Minaguchi, Kanji Kobayashi, Satoru Sagae, Ryuichi Kudo, Naoki Terakawa and Yusuke Nakamura
    Cancer Res September 1 1999 59 (17) 4225-4227;

  • Advances in Brief
    Reactivation of Insulin-like Growth Factor Binding Protein 2 Expression in Glioblastoma Multiforme
    Gregory N. Fuller, Chang Hun Rhee, Kenneth R. Hess, Laura S. Caskey, Ruoping Wang, Janet M. Bruner, W. K. Alfred Yung and Wei Zhang
    Cancer Res September 1 1999 59 (17) 4228-4232;

  • Advances in Brief
    Distinct Expression Patterns of the p53-Homologue p73 in Malignant and Normal Hematopoiesis Assessed by a Novel Real-Time Reverse Transcription-Polymerase Chain Reaction Assay and Protein Analysis
    Uwe R. Peters, Mario P. Tschan, Karl A. Kreuzer, Gökben Baskaynak, Ulrich Lass, Andreas Tobler, Martin F. Fey and Christian A. Schmidt
    Cancer Res September 1 1999 59 (17) 4233-4236;

  • Advances in Brief
    The Mouse Bcrp1/Mxr/Abcp Gene
    John D. Allen, Remco F. Brinkhuis, Jan Wijnholds and Alfred H. Schinkel
    Cancer Res September 1 1999 59 (17) 4237-4241;

  • Advances in Brief
    A Single Targeted Ets2 Allele Restricts Development of Mammary Tumors in Transgenic Mice
    Nickolay Neznanov, Albert K. Man, Hideyuki Yamamoto, Craig A. Hauser, Robert D. Cardiff and Robert G. Oshima
    Cancer Res September 1 1999 59 (17) 4242-4246;

  • Advances in Brief
    Wild-Type p53 Induction Mediated by Replication-deficient Adenoviral Vectors
    Christina R. McPake, Sheetal Shetty, Geoffrey R. Kitchingman and Linda C. Harris
    Cancer Res September 1 1999 59 (17) 4247-4251;

  • Advances in Brief
    Prostase/KLK-L1 Is a New Member of the Human Kallikrein Gene Family, Is Expressed in Prostate and Breast Tissues, and Is Hormonally Regulated
    George M. Yousef, Christina V. Obiezu, Liu-Ying Luo, Margot H. Black and Eleftherios P. Diamandis
    Cancer Res September 1 1999 59 (17) 4252-4256;

  • Advances in Brief
    Frequent Somatic Mutations of the β-Catenin Gene in Intestinal-Type Gastric Cancer
    Won Sang Park, Ro Ra Oh, Jik Young Park, Sug Hyung Lee, Min Sun Shin, Young Sil Kim, Su Young Kim, Hyun Kyung Lee, Pum Joon Kim, Seong Taek Oh, Nam Jin Yoo and Jung Young Lee
    Cancer Res September 1 1999 59 (17) 4257-4260;

  • Advances in Brief
    AF17q25, a Putative Septin Family Gene, Fuses the MLL Gene in Acute Myeloid Leukemia with t(11;17)(q23;q25)
    Tomohiko Taki, Hiroaki Ohnishi, Kenji Shinohara, Masahiro Sako, Fumio Bessho, Masayoshi Yanagisawa and Yasuhide Hayashi
    Cancer Res September 1 1999 59 (17) 4261-4265;

  • Advances in Brief
    Sp3, but not Sp1, Mediates the Transcriptional Activation of the p21/WAF1/Cip1 Gene Promoter by Histone Deacetylase Inhibitor
    Yoshihiro Sowa, Tetsuro Orita, Sachie Minamikawa-Hiranabe, Takakazu Mizuno, Hitoshi Nomura and Toshiyuki Sakai
    Cancer Res September 1 1999 59 (17) 4266-4270;

Biochemistry

  • Biochemistry
    Mode of Action of a New Indolocarbazole Anticancer Agent, J-107088, Targeting Topoisomerase I
    Tomoko Yoshinari, Mitsuru Ohkubo, Kazuhiro Fukasawa, Shin-ichirou Egashira, Yoshikazu Hara, Mami Matsumoto, Kiyoshi Nakai, Hiroharu Arakawa, Hajime Morishima and Susumu Nishimura
    Cancer Res September 1 1999 59 (17) 4271-4275;

Carcinogenesis

  • Carcinogenesis
    Murine Mammary Gland Carcinogenesis Is Critically Dependent on Progesterone Receptor Function
    John P. Lydon, Gouqing Ge, Francis S. Kittrell, Daniel Medina and Bert W. O’Malley
    Cancer Res September 1 1999 59 (17) 4276-4284;

  • Carcinogenesis
    Patterns of DNA Adduct Formation in Liver and Mammary Epithelial Cells of Rats Treated with 7,12-Dimethylbenz(a)anthracene, and Selective Effects of Chemopreventive Agents
    Alberto Izzotti, Anna Camoirano, Cristina Cartiglia, Clinton J. Grubbs, Ronald A. Lubet, Gary J. Kelloff and Silvio De Flora
    Cancer Res September 1 1999 59 (17) 4285-4290;

Clinical Investigations

  • Clinical Investigations
    Loss of PTEN Expression in Paraffin-embedded Primary Prostate Cancer Correlates with High Gleason Score and Advanced Stage
    Máirín E. McMenamin, Peggy Soung, Sauni Perera, Irving Kaplan, Massimo Loda and William R. Sellers
    Cancer Res September 1 1999 59 (17) 4291-4296;

  • Clinical Investigations
    Effect of c-kit Mutation on Prognosis of Gastrointestinal Stromal Tumors
    Masahiko Taniguchi, Toshirou Nishida, Seiichi Hirota, Koji Isozaki, Toshinori Ito, Taisei Nomura, Hikaru Matsuda and Yukihiko Kitamura
    Cancer Res September 1 1999 59 (17) 4297-4300;

  • Clinical Investigations
    High Telomerase Reverse Transcriptase (hTERT) Messenger RNA Level Correlates with Tumor Recurrence in Patients with Favorable Histology Wilms’ Tumor
    Jeffrey S. Dome, Seung Chung, Tracy Bergemann, Christopher B. Umbricht, Motoyasu Saji, Lisa A. Carey, Paul E. Grundy, Elizabeth J. Perlman, Norman E. Breslow and Saraswati Sukumar
    Cancer Res September 1 1999 59 (17) 4301-4307;

Endocrinology

  • Endocrinology
    The Interaction of Raloxifene and the Active Metabolite of the Antiestrogen EM-800 (SC 5705) with the Human Estrogen Receptor
    Jennifer I. MacGregor Schafer, Hong Liu, Debra A. Tonetti and V. Craig Jordan
    Cancer Res September 1 1999 59 (17) 4308-4313;

  • Endocrinology
    Altered Ligand Binding by Insulin-like Growth Factor II/Mannose 6-Phosphate Receptors Bearing Missense Mutations in Human Cancers
    Gayathri R. Devi, Angus T. De Souza, James C. Byrd, Randy L. Jirtle and Richard G. MacDonald
    Cancer Res September 1 1999 59 (17) 4314-4319;

Epidemiology and Prevention

  • Epidemiology and Prevention
    Well-done, Grilled Red Meat Increases the Risk of Colorectal Adenomas
    Rashmi Sinha, Wong Ho Chow, Martin Kulldorff, John Denobile, James Butler, Montserrat Garcia-Closas, Rusty Weil, Robert N. Hoover and Nathaniel Rothman
    Cancer Res September 1 1999 59 (17) 4320-4324;

Experimental Therapeutics

  • Experimental Therapeutics
    Inhibition of Cancer Cell Growth by Polyinosinic-Polycytidylic Acid/Cationic Liposome Complex: A New Biological Activity
    Kazuko Hirabayashi, Junichi Yano, Toshihiko Inoue, Tohru Yamaguchi, Kazuaki Tanigawara, Gerald E. Smyth, Kouichi Ishiyama, Tadaaki Ohgi, Kiyoshi Kimura and Tatsuro Irimura
    Cancer Res September 1 1999 59 (17) 4325-4333;

  • Experimental Therapeutics
    Photofrin-mediated Photodynamic Therapy Induces Vascular Occlusion and Apoptosis in a Human Sarcoma Xenograft Model
    Brett W. Engbrecht, Chandrakala Menon, Alexander V. Kachur, Stephen M. Hahn and Douglas L. Fraker
    Cancer Res September 1 1999 59 (17) 4334-4342;

  • Experimental Therapeutics
    Apoptosis Induction by a Novel Anti-Prostate Cancer Compound, BMD188 (a Fatty Acid-containing Hydroxamic Acid), Requires the Mitochondrial Respiratory Chain
    Bindu Joshi, Li Li, Bonita G. Taffe, Zhenyu Zhu, Sharon Wahl, Hongsheng Tian, Edgar Ben-Josef, John D. Taylor, Arthur T. Porter and Dean G. Tang
    Cancer Res September 1 1999 59 (17) 4343-4355;

  • Experimental Therapeutics
    Increased Cyclooxygenase-2 Expression in Human Pancreatic Carcinomas and Cell Lines
    Miguel A. Molina, Marta Sitja-Arnau, Michael G. Lemoine, Marsha L. Frazier and Frank A. Sinicrope
    Cancer Res September 1 1999 59 (17) 4356-4362;

  • Experimental Therapeutics
    Direct Demonstration in Synthetic Oligonucleotides that N,N′-Bis(2-chloroethyl)-nitrosourea Cross-Links N1 of Deoxyguanosine to N3 of Deoxycytidine on Opposite Strands of Duplex DNA
    Paula L. Fischhaber, Anna S. Gall, James A. Duncan and Paul B. Hopkins
    Cancer Res September 1 1999 59 (17) 4363-4368;

  • Experimental Therapeutics
    p53 Selective and Nonselective Replication of an E1B-deleted Adenovirus in Hepatocellular Carcinoma
    Charles M. Vollmer, Antoni Ribas, Lisa H. Butterfield, Vivian B. Dissette, Kahlil J. Andrews, Fritz C. Eilber, Lara D. Montejo, Angela Y. Chen, Billy Hu, John A. Glaspy, William H. McBride and James S. Economou
    Cancer Res September 1 1999 59 (17) 4369-4374;

  • Experimental Therapeutics
    Inhibition of ATM and ATR Kinase Activities by the Radiosensitizing Agent, Caffeine
    Jann N. Sarkaria, Ericka C. Busby, Randal S. Tibbetts, Pia Roos, Yoichi Taya, Larry M. Karnitz and Robert T. Abraham
    Cancer Res September 1 1999 59 (17) 4375-4382;

  • Experimental Therapeutics
    Glioma Cells Release Excitotoxic Concentrations of Glutamate
    Zu-Cheng Ye and Harald Sontheimer
    Cancer Res September 1 1999 59 (17) 4383-4391;

  • Experimental Therapeutics
    Hybrid Polar Histone Deacetylase Inhibitor Induces Apoptosis and CD95/CD95 Ligand Expression in Human Neuroblastoma
    Richard D. Glick, Steven L. Swendeman, Dennis C. Coffey, Richard A. Rifkind, Paul A. Marks, Victoria M. Richon and Michael P. La Quaglia
    Cancer Res September 1 1999 59 (17) 4392-4399;

  • Experimental Therapeutics
    Pretargeting of Renal Cell Carcinoma: Improved Tumor Targeting with a Bivalent Chelate
    Otto C. Boerman, Marion H. G. C. Kranenborg, Egbert Oosterwijk, Gary L. Griffiths, William J. McBride, Wim J. G. Oyen, Mirjam de Weijert, Jeannette Oosterwijk-Wakka, Hans J. Hansen and Frans H. M. Corstens
    Cancer Res September 1 1999 59 (17) 4400-4405;

  • Experimental Therapeutics
    Decrease in Susceptibility Toward Induction of Apoptosis and Alteration in G1 Checkpoint Function as Determinants of Resistance of Human Lung Cancer Cells against the Antisignaling Drug UCN-01 (7-Hydroxystaurosporine)
    Kazuyo Sugiyama, Tadakazu Akiyama, Makiko Shimizu, Tatsuya Tamaoki, Carol Courage, Andreas Gescher and Shiro Akinaga
    Cancer Res September 1 1999 59 (17) 4406-4412;

Tumor Biology

  • Tumor Biology
    Protein Kinase C Lies on the Signaling Pathway for Vascular Endothelial Growth Factor-mediated Tumor Development and Angiogenesis
    Hitoshi Yoshiji, Shigeki Kuriyama, D. Kirk Ways, Junichi Yoshii, Yoji Miyamoto, Mitsuhiro Kawata, Yasuhide Ikenaka, Hirohisa Tsujinoue, Toshiya Nakatani, Masabumi Shibuya and Hiroshi Fukui
    Cancer Res September 1 1999 59 (17) 4413-4418;

  • Tumor Biology
    The Role of Hyaluronan and Interleukin 8 in the Migration of Chronic Lymphocytic Leukemia Cells within Lymphoreticular Tissues
    Kathleen J. Till, Mirko Zuzel and John C. Cawley
    Cancer Res September 1 1999 59 (17) 4419-4426;

  • Tumor Biology
    CD44 Stimulation Induces Integrin-mediated Adhesion of Colon Cancer Cell Lines to Endothelial Cells by Up-Regulation of Integrins and c-Met and Activation of Integrins
    Takeshi Fujisaki, Yoshiya Tanaka, Koichi Fujii, Shinichiro Mine, Kazuyoshi Saito, Shinwa Yamada, Uki Yamashita, Tatsuro Irimura and Sumiya Eto
    Cancer Res September 1 1999 59 (17) 4427-4434;

  • Tumor Biology
    Cloning of Tumor-associated Differentially Expressed Gene-14, a Novel Serine Protease Overexpressed by Ovarian Carcinoma
    Lowell J. Underwood, Hirotoshi Tanimoto, Yinxiang Wang, Kazushi Shigemasa, Tim H. Parmley and Timothy J. O’Brien
    Cancer Res September 1 1999 59 (17) 4435-4439;

  • Tumor Biology
    Regulation of the Urokinase-type Plasminogen Activator System by the von Hippel-Lindau Tumor Suppressor Gene
    Maartje Los, Saida Zeamari, John A. Foekens, Martijn F. B. G. Gebbink and Emile E. Voest
    Cancer Res September 1 1999 59 (17) 4440-4445;

  • Tumor Biology
    Inhibition of Nuclear Factor-κB Activation Confers Sensitivity to Tumor Necrosis Factor-α by Impairment of Cell Cycle Progression in Human Glioma Cells
    Goro Otsuka, Takashi Nagaya, Kiyoshi Saito, Masaaki Mizuno, Jun Yoshida and Hisao Seo
    Cancer Res September 1 1999 59 (17) 4446-4452;

  • Tumor Biology
    Osteonectin Promotes Prostate Cancer Cell Migration and Invasion
    Karin Jacob, Mukta Webber, Dafna Benayahu and Hynda K. Kleinman
    Cancer Res September 1 1999 59 (17) 4453-4457;

  • Tumor Biology
    Cellular Membrane Permeability of Anthracyclines Does Not Correlate with Their Delivery in a Tissue-isolated Tumor
    Marc Heijn, Sylvie Roberge and Rakesh K. Jain
    Cancer Res September 1 1999 59 (17) 4458-4463;

  • Tumor Biology
    Identification of Bladder Tumor-derived Hyaluronidase: Its Similarity to HYAL1
    Vinata B. Lokeshwar, Marvin J. Young, Gulten Goudarzi, Naoko Iida, Ashley I. Yudin, Gary N. Cherr and Marie G. Selzer
    Cancer Res September 1 1999 59 (17) 4464-4470;

Letters to the Editor

  • Letters to the Editor
    Correspondence re: Y. Chen et al., DNA Vaccines Encoding Full-Length or Truncated Neu Induce Protective Immunity against Neu-expressing Mammary Tumors. Cancer Res., 58: 1965–1971, 1998.
    Roberta De Vecchi, Serenella M. Pupa, Sylvie Ménard and Pier-Luigi Lollini
    Cancer Res September 1 1999 59 (17) 4471-4472;

Errata

  • Errata
    July 1, 1999 Cancer Research cover legend
    Cancer Res September 1 1999 59 (17) 4473-4476;

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September 1999
Volume 59, Issue 17
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Cancer Research Online ISSN: 1538-7445
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