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Table of Contents

Public Issues

  • Public Issues
    Prevention of Cancer in the Next Millennium
    Cancer Res October 1 1999 59 (19) 4743-4758;

Perspectives in Cancer Research

  • Perspectives in Cancer Research
    Application of Complementary DNA Microarray Technology to Carcinogen Identification, Toxicology, and Drug Safety Evaluation
    Cynthia A. Afshari, Emile F. Nuwaysir and J. Carl Barrett
    Cancer Res October 1 1999 59 (19) 4759-4760;

Advances in Brief

  • Advances in Brief
    Response of Prostate Cancer to Anti-Her-2/neu Antibody in Androgen-dependent and -independent Human Xenograft Models
    David B. Agus, Howard I. Scher, Brian Higgins, William D. Fox, Glenn Heller, Melissa Fazzari, Carlos Cordon-Cardo and David W. Golde
    Cancer Res October 1 1999 59 (19) 4761-4764;

  • Advances in Brief
    Dominant-Negative Mutations of the Tumor Suppressor p53 Relating to Early Onset of Glioblastoma Multiforme
    Masumi Marutani, Hidefumi Tonoki, Mitsuhiro Tada, Masato Takahashi, Haruhiko Kashiwazaki, Yasuhiro Hida, Jun-ich Hamada, Masahiro Asaka and Tetsuya Moriuchi
    Cancer Res October 1 1999 59 (19) 4765-4769;

  • Advances in Brief
    Tumor Development under Angiogenic Signaling
    Philip Hahnfeldt, Dipak Panigrahy, Judah Folkman and Lynn Hlatky
    Cancer Res October 1 1999 59 (19) 4770-4775;

  • Advances in Brief
    Addition of Peroxisome Proliferator-activated Receptor α to Guinea Pig Hepatocytes Confers Increased Responsiveness to Peroxisome Proliferators
    Neil Macdonald, Peter R. Holden and Ruth A. Roberts
    Cancer Res October 1 1999 59 (19) 4776-4780;

  • Advances in Brief
    Solid Tissues Removed from Atm Homozygous Deficient Mice Do Not Exhibit a Mutator Phenotype for Second-Step Autosomal Mutations
    Mitchell S. Turker, Blythe M. Gage, Jennifer A. Rose, Olga N. Ponomareva, Jay A. Tischfield, Peter J. Stambrook, Carrolee Barlow and Anthony Wynshaw-Boris
    Cancer Res October 1 1999 59 (19) 4781-4783;

  • Advances in Brief
    p53-Mutant Clones and Field Effects in Barrett’s Esophagus
    Laura J. Prevo, Carissa A. Sanchez, Patricia C. Galipeau and Brian J. Reid
    Cancer Res October 1 1999 59 (19) 4784-4787;

  • Advances in Brief
    Functional Activity of Ectopically Expressed Estrogen Receptor Is Not Sufficient for Estrogen-mediated Cyclin D1 Expression
    Maricarmen D. Planas-Silva, Joana Liu Donaher and Robert A. Weinberg
    Cancer Res October 1 1999 59 (19) 4788-4792;

  • Advances in Brief
    The Expression of a Truncated HMGI-C Gene Induces Gigantism Associated with Lipomatosis
    Sabrina Battista, Vincenzo Fidanza, Monica Fedele, Andres J. P. Klein-Szanto, Eric Outwater, Han Brunner, Massimo Santoro, Carlo M. Croce and Alfredo Fusco
    Cancer Res October 1 1999 59 (19) 4793-4797;

  • Advances in Brief
    Loss of Fhit Is Frequent in Stage I Non-Small Cell Lung Cancer and in the Lungs of Chronic Smokers
    Jennifer E. Tseng, Bonnie L. Kemp, Fadlo R. Khuri, Jonathan M. Kurie, Jin Soo Lee, Xiao Zhou, Diane Liu, Waun Ki Hong and Li Mao
    Cancer Res October 1 1999 59 (19) 4798-4803;

  • Advances in Brief
    Extracellular Signal-regulated Kinase Activation Is Required for Up-Regulation of Vascular Endothelial Growth Factor by Serum Starvation in Human Colon Carcinoma Cells
    Young D. Jung, Kayo Nakano, Wenbiao Liu, Gary E. Gallick and Lee M. Ellis
    Cancer Res October 1 1999 59 (19) 4804-4807;

Biochemistry

  • Biochemistry
    Decreased Sensitivity to 1-O-Octadecyl-2-O-methyl-glycerophosphocholine in MCF-7 Cells Adapted for Serum-free Growth Correlates with Constitutive Association of Raf-1 with Cellular Membranes
    Pranati Samadder and Gilbert Arthur
    Cancer Res October 1 1999 59 (19) 4808-4815;

  • Biochemistry
    Additivity of Dilantin and Vinblastine Inhibitory Effects on Microtubule Assembly
    Sharon Lobert, Jeffrey W. Ingram and John J. Correia
    Cancer Res October 1 1999 59 (19) 4816-4822;

Carcinogenesis

  • Carcinogenesis
    High-Salt Diet Induces Gastric Epithelial Hyperplasia and Parietal Cell Loss, and Enhances Helicobacter pylori Colonization in C57BL/6 Mice
    James G. Fox, Charles A. Dangler, Nancy S. Taylor, Amy King, Theodore J. Koh and Timothy C. Wang
    Cancer Res October 1 1999 59 (19) 4823-4828;

  • Carcinogenesis
    Tamoxifen-DNA Adduct Formation in Rat Liver Determined by Immunoassay and 32P-Postlabeling
    Rao L. Divi, Martin R. Osborne, Alan Hewer, David H. Phillips and Miriam C. Poirier
    Cancer Res October 1 1999 59 (19) 4829-4833;

  • Carcinogenesis
    Loss of Responsiveness to Transforming Growth Factor β Induces Malignant Transformation of Nontumorigenic Rat Prostate Epithelial Cells
    Binwu Tang, Katherine de Castro, Helen E. Barnes, W. Tony Parks, LaMonica Stewart, Erwin P. Böttinger, David Danielpour and Lalage M. Wakefield
    Cancer Res October 1 1999 59 (19) 4834-4842;

  • Carcinogenesis
    Extracellular Matrix and Radiation G1 Cell Cycle Arrest in Human Fibroblasts
    Mira Dimitrijevic-Bussod, Viviana S. Balzaretti-Maggi and Donna M. Gadbois
    Cancer Res October 1 1999 59 (19) 4843-4847;

Endocrinology

  • Endocrinology
    Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p53
    Ida Stenfeldt Mathiasen, Ulrikm Lademann and Marja Jäättelä
    Cancer Res October 1 1999 59 (19) 4848-4856;

  • Endocrinology
    Effect of Combined Treatment with the Pure Antiestrogen EM-800 and Radiotherapy on the Growth of Human ZR-75-1 Breast Cancer Xenografts in Nude Mice
    Steeve Couillard, Matthieu Gutman, Fernand Labrie, Bernard Candas and Claude Labrie
    Cancer Res October 1 1999 59 (19) 4857-4863;

  • Endocrinology
    Adrenal Androgens Stimulate the Proliferation of Breast Cancer Cells as Direct Activators of Estrogen Receptor α
    Marcello Maggiolini, Olivier Donzé, Elisabeth Jeannin, Sebastiano Andò and Didier Picard
    Cancer Res October 1 1999 59 (19) 4864-4869;

Epidemiology and Prevention

  • Epidemiology and Prevention
    Breast Cancer Risk Associated with Genotype Polymorphism of the Estrogen-metabolizing Genes CYP17, CYP1A1, and COMT
    Chiun-Sheng Huang, Herng-Der Chern, King-Jen Chang, Chun-Wen Cheng, Su-Ming Hsu and Chen-Yang Shen
    Cancer Res October 1 1999 59 (19) 4870-4875;

Experimental Therapeutics

  • Experimental Therapeutics
    Antisense Cyclin D1 Induces Apoptosis and Tumor Shrinkage in Human Squamous Carcinomas
    Edward R. Sauter, Mark Nesbit, Samuel Litwin, Andres J. P. Klein-Szanto, Susan Cheffetz and Meenhard Herlyn
    Cancer Res October 1 1999 59 (19) 4876-4881;

  • Experimental Therapeutics
    Hypoxia-mediated Apoptosis from Angiogenesis Inhibition Underlies Tumor Control by Recombinant Interleukin 12
    Michael S. Gee, Cameron J. Koch, Sydney M. Evans, W. Timothy Jenkins, Charles H. Pletcher Jr., Jonni S. Moore, Holly K. Koblish, Jungeun Lee, Edith M. Lord, Giorgio Trinchieri and William M. F. Lee
    Cancer Res October 1 1999 59 (19) 4882-4889;

  • Experimental Therapeutics
    Mouse Transporter Protein, a Membrane Protein That Regulates Cellular Multidrug Resistance, Is Localized to Lysosomes
    Miguel A. Cabrita, Tom C. Hobman, Douglas L. Hogue, Karen M. King and Carol E. Cass
    Cancer Res October 1 1999 59 (19) 4890-4897;

  • Experimental Therapeutics
    Potent Topoisomerase I Inhibition by Novel Silatecans Eliminates Glioma Proliferation in Vitro and in Vivo
    Ian F. Pollack, Melanie Erff, David Bom, Thomas G. Burke, J. Thompson Strode and Dennis P. Curran
    Cancer Res October 1 1999 59 (19) 4898-4905;

  • Experimental Therapeutics
    Application of the Cre Recombinase/loxP System Further Enhances Antitumor Effects in Cell Type-specific Gene Therapy against Carcinoembryonic Antigen-producing Cancer
    Takashi Kijima, Tadashi Osaki, Kazumi Nishino, Toru Kumagai, Toshiki Funakoshi, Hiroyuki Goto, Isao Tachibana, Yoshiro Tanio and Tadamitsu Kishimoto
    Cancer Res October 1 1999 59 (19) 4906-4911;

  • Experimental Therapeutics
    Electromotive versus Passive Diffusion of Mitomycin C into Human Bladder Wall
    Savino M. Di Stasi, Antonella Giannantoni, Renato Massoud, Susanna Dolci, Pierluigi Navarra, Giuseppe Vespasiani and Robert L. Stephen
    Cancer Res October 1 1999 59 (19) 4912-4918;

  • Experimental Therapeutics
    Antitumor Efficacy of a Novel Class of Non-thiol-containing Peptidomimetic Inhibitors of Farnesyltransferase and Geranylgeranyltransferase I
    Jiazhi Sun, Michelle A. Blaskovich, David Knowles, Yimin Qian, Junko Ohkanda, Ratna D. Bailey, Andrew D. Hamilton and Saïd M. Sebti
    Cancer Res October 1 1999 59 (19) 4919-4926;

  • Experimental Therapeutics
    Transfection of 9-Hydroxyellipticine-resistant Chinese Hamster Fibroblasts with Human Topoisomerase IIα cDNA
    Tayeb Khélifa, Brigitte René, Sandrine Le Mée, Bernard Lambert, Jean-Marie Saucier, Judith Markovits, Hélène Jacquemin-Sablon and Alain Jacquemin-Sablon
    Cancer Res October 1 1999 59 (19) 4927-4936;

  • Experimental Therapeutics
    Arabinosylguanine-induced Apoptosis of T-Lymphoblastic Cells
    Carlos O. Rodriguez Jr. and Varsha Gandhi
    Cancer Res October 1 1999 59 (19) 4937-4943;

  • Experimental Therapeutics
    The Polyamine Oxidase Inhibitor MDL-72,527 Selectively Induces Apoptosis of Transformed Hematopoietic Cells through Lysosomotropic Effects
    Haiqing Dai, Debora L. Kramer, Chunying Yang, K. Gopal Murti, Carl W. Porter and John L. Cleveland
    Cancer Res October 1 1999 59 (19) 4944-4954;

Immunology

  • Immunology
    Modified Vaccinia Virus Ankara for Delivery of Human Tyrosinase as Melanoma-associated Antigen
    Ingo Drexler, Edite Antunes, Marc Schmitz, Thomas Wölfel, Christoph Huber, Volker Erfle, Peter Rieber, Matthias Theobald and Gerd Sutter
    Cancer Res October 1 1999 59 (19) 4955-4963;

  • Immunology
    Potent Activity of Soluble B7-IgG Fusion Proteins in Therapy of Established Tumors and as Vaccine Adjuvant
    Knut Sturmhoefel, Kwang Lee, Gary S. Gray, Jenifer Thomas, Richard Zollner, Margot O’Toole, Holly Swiniarski, Andrew Dorner and Stanley F. Wolf
    Cancer Res October 1 1999 59 (19) 4964-4972;

Molecular Biology and Genetics

  • Molecular Biology and Genetics
    Expression of OVCA1, a Candidate Tumor Suppressor, Is Reduced in Tumors and Inhibits Growth of Ovarian Cancer Cells
    Wendy Bruening, Amanda H. Prowse, David C. Schultz, Marina Holgado-Madruga, Albert Wong and Andrew K. Godwin
    Cancer Res October 1 1999 59 (19) 4973-4983;

  • Molecular Biology and Genetics
    Kaposi’s Sarcoma-associated Herpesvirus-encoded v-Cyclin Triggers Apoptosis in Cells with High Levels of Cyclin-dependent Kinase 6
    Päivi M. Ojala, Marianne Tiainen, Petri Salven, Tanja Veikkola, Esmeralda Castaños-Vélez, Ronit Sarid, Peter Biberfeld and Tomi P. Mäkelä
    Cancer Res October 1 1999 59 (19) 4984-4989;

  • Molecular Biology and Genetics
    Identification and Characterization of Genes Associated with Human Hepatocellular Carcinogenesis
    Nobuo Kondoh, Toru Wakatsuki, Akihide Ryo, Akiyuki Hada, Tsukasa Aihara, Sankichi Horiuchi, Narihide Goseki, Osamu Matsubara, Kenji Takenaka, Mizue Shichita, Kenji Tanaka, Masahiro Shuda and Mikio Yamamoto
    Cancer Res October 1 1999 59 (19) 4990-4996;

  • Molecular Biology and Genetics
    Genomic Structure, Chromosomal Mapping, and Promoter Region Analysis of Murine Uridine Phosphorylase Gene
    Deliang Cao, Manjunath A. Nimmakayalu, Feiya Wang, Dekai Zhang, Robert E. Handschumacher, Patricia Bray-Ward and Giuseppe Pizzorno
    Cancer Res October 1 1999 59 (19) 4997-5001;

Tumor Biology

  • Tumor Biology
    Carcinoma-associated Fibroblasts Direct Tumor Progression of Initiated Human Prostatic Epithelium
    Aria F. Olumi, Gary D. Grossfeld, Simon W. Hayward, Peter R. Carroll, Thea D. Tlsty and Gerald R. Cunha
    Cancer Res October 1 1999 59 (19) 5002-5011;

  • Tumor Biology
    In Vivo Prediction of Vascular Susceptibility to Vascular Endothelial Growth Factor Withdrawal
    Rinat Abramovitch, Hagit Dafni, Eitzik Smouha, Laura E. Benjamin and Michal Neeman
    Cancer Res October 1 1999 59 (19) 5012-5016;

  • Tumor Biology
    Paradoxical Inhibition of c-myc-induced Carcinogenesis by Bcl-2 in Transgenic Mice
    Alix de La Coste, Alexandre Mignon, Monique Fabre, Emmanuelle Gilbert, Arlette Porteu, Terry Van Dyke, Axel Kahn and Christine Perret
    Cancer Res October 1 1999 59 (19) 5017-5022;

  • Tumor Biology
    Overexpression of Fibroblast Growth Factor 1 in MCF-7 Breast Cancer Cells Facilitates Tumor Cell Dissemination but Does Not Support the Development of Macrometastases in the Lungs or Lymph Nodes
    Lurong Zhang, Samir Kharbanda, Sandra W. McLeskey and Francis G. Kern
    Cancer Res October 1 1999 59 (19) 5023-5029;

  • Tumor Biology
    Evidence for Clonal Outgrowth of Androgen-independent Prostate Cancer Cells from Androgen-dependent Tumors through a Two-Step Process
    Noah Craft, Chloe Chhor, Chris Tran, Arie Belldegrun, Jean DeKernion, Owen N. Witte, Jonathan Said, Robert E. Reiter and Charles L. Sawyers
    Cancer Res October 1 1999 59 (19) 5030-5036;

  • Tumor Biology
    Thymidine Phosphorylase Expression Is Associated with Both Increase of Intratumoral Microvessels and Decrease of Apoptosis in Human Colorectal Carcinomas
    Takahiko Matsuura, Itaru Kuratate, Kazuki Teramachi, Mitsuhiko Osaki, Yasuhiko Fukuda and Hisao Ito
    Cancer Res October 1 1999 59 (19) 5037-5040;

  • Tumor Biology
    A Soluble Transforming Growth Factor β Type III Receptor Suppresses Tumorigenicity and Metastasis of Human Breast Cancer MDA-MB-231 Cells
    Abhik Bandyopadhyay, Yong Zhu, Michael L. Cibull, LiWei Bao, Changguo Chen and LuZhe Sun
    Cancer Res October 1 1999 59 (19) 5041-5046;

  • Tumor Biology
    Induction of Apoptosis by Arachidonic Acid in Chronic Myeloid Leukemia Cells
    Maria Teresa Rizzo, Ester Regazzi, Daniela Garau, Luke Akard, Michael Dugan, H. Scott Boswell, Vittorio Rizzoli and Carmelo Carlo-Stella
    Cancer Res October 1 1999 59 (19) 5047-5053;

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October 1999
Volume 59, Issue 19
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