Table of Contents

Advances in Brief

• Advances in Brief

  Frequent β-Catenin Gene Mutations and Accumulations of the Protein in the Putative Preneoplastic Lesions Lacking Macroscopic Aberrant Crypt Foci Appearance, in Rat Colon Carcinogenesis

  Yasuhiro Yamada, Naoki Yoshimi, Yoshinobu Hirose, Kunihiro Kawabata, Kengo Matsunaga, Masahito Shimizu, Akira Hara and Hideki Mori

  Cancer Res July 1 2000 60 (13) 3323-3327;

  
  
• Advances in Brief

  The Epidermal Growth Factor Receptor Is Required to Maintain the Proliferative Population in the Basal Compartment of Epidermal Tumors

  Laura A. Hansen, Roderick L. Woodson II, Sherry Holbus, Kathryn Strain, You-Chein Lo and Stuart H. Yuspa

  Cancer Res July 1 2000 60 (13) 3328-3332;

  
  
• Advances in Brief

  Increased p53 Mutation Load in Noncancerous Colon Tissue from Ulcerative Colitis: A Cancer-prone Chronic Inflammatory Disease

  S. Perwez Hussain, Paul Amstad, Kamran Raja, Stefan Ambs, Makoto Nagashima, William P. Bennett, Peter G. Shields, Amy-Joan Ham, James A. Swenberg, Aizen J. Marrogi and Curtis C. Harris

  Cancer Res July 1 2000 60 (13) 3333-3337;

  
  
• Advances in Brief

  Exisulind Induction of Apoptosis Involves Guanosine 3′,5′-Cyclic Monophosphate Phosphodiesterase Inhibition, Protein Kinase G Activation, and Attenuated β-Catenin

  W. Joseph Thompson, Gary A. Piazza, Han Li, Li Liu, John Fetter, Bing Zhu, Gerhard Sperl, Dennis Ahnen and Rifat Pamukcu

  Cancer Res July 1 2000 60 (13) 3338-3342;

  
  
• Advances in Brief

  Inhibition of Metastatic Tumor Growth in Nude Mice by Portal Vein Infusions of Matrix-targeted Retroviral Vectors Bearing a Cytocidal Cyclin G1 Construct

  Erlinda M. Gordon, Peng Xuan Liu, Zhen Hai Chen, Ling Liu, Michelle D. Whitley, Conway Gee, Susan Groshen, David R. Hinton, Robert W. Beart and Frederick L. Hall

  Cancer Res July 1 2000 60 (13) 3343-3347;

  
  
• Advances in Brief

  High Resolution Allelotype of Microdissected Primary Nasopharyngeal Carcinoma

  Kwok-Wai Lo, Peter M. L. Teo, Angela Bik-Yu Hui, Ka-Fai To, Yuen-Shan Tsang, Sylvia Yat-Yee Chan, Ko-Fung Mak, Joseph C. K. Lee and Dolly P. Huang

  Cancer Res July 1 2000 60 (13) 3348-3353;

  
  
• Advances in Brief

  Isolation and Characterization of a Novel Human Gene, DRCTNNB1A, the Expression of Which Is Down-Regulated by β-Catenin

  Teru Kawasoe, Yoichi Furukawa, Yataro Daigo, Tadashi Nishiwaki, Hideyuki Ishiguro, Manabu Fujita, Seiji Satoh, Nobutomo Miwa, Yutaka Nagasawa, Yasuo Miyoshi, Michio Ogawa and Yusuke Nakamura

  Cancer Res July 1 2000 60 (13) 3354-3358;

  
  
• Advances in Brief

  Down-Regulation of HP1^Hsα Expression Is Associated with the Metastatic Phenotype in Breast Cancer

  Dawn A. Kirschmann, Ruth A. Lininger, Lynn M. G. Gardner, Elisabeth A. Seftor, Valerie A. Odero, Alexandra M. Ainsztein, William C. Earnshaw, Lori L. Wallrath and Mary J. C. Hendrix

  Cancer Res July 1 2000 60 (13) 3359-3363;

  
  
• Advances in Brief

  Front-Cell-specific Expression of Membrane-Type 1 Matrix Metalloproteinase and Gelatinase A during Cohort Migration of Colon Carcinoma Cells Induced by Hepatocyte Growth Factor/Scatter Factor

  Kazuki Nabeshima, Teruhiko Inoue, Yoshiya Shimao, Yasunori Okada, Yoshifumi Itoh, Motoharu Seiki and Masashi Koono

  Cancer Res July 1 2000 60 (13) 3364-3369;

  
  
• Advances in Brief

  Frequent Alteration of p63 Expression in Human Primary Bladder Carcinomas

  Bum-Joon Park, Seung-Jae Lee, Jin Il Kim, Sun-Ju Lee, Choong-Hyun Lee, Sung-Goo Chang, Jae-Hoon Park and Sung-Gil Chi

  Cancer Res July 1 2000 60 (13) 3370-3374;

  
  
• Advances in Brief

  Carcinogenic Metals Induce Hypoxia-inducible Factor-stimulated Transcription by Reactive Oxygen Species-independent Mechanism

  Konstantin Salnikow, Weicheng Su, Mikhail V. Blagosklonny and Max Costa

  Cancer Res July 1 2000 60 (13) 3375-3378;

  
  
• Advances in Brief

  Differential Formation of β-Catenin/Lymphoid Enhancer Factor-1 DNA Binding Complex Induced by Nitric Oxide in Mouse Colonic Epithelial Cells Differing in Adenomatous Polyposis Coli (Apc) Genotype

  Jay M. Mei, Norman G. Hord, Dolores F. Winterstein, Steven P. Donald and James M. Phang

  Cancer Res July 1 2000 60 (13) 3379-3383;

  
  
• Advances in Brief

  Tumor-inhibitory Antibodies to HER-2/ErbB-2 May Act by Recruiting c-Cbl and Enhancing Ubiquitination of HER-2

  Leah N. Klapper, Hadassa Waterman, Michael Sela and Yosef Yarden

  Cancer Res July 1 2000 60 (13) 3384-3388;

  
  
• Advances in Brief

  Liposomal Encapsulation of Topotecan Enhances Anticancer Efficacy in Murine and Human Xenograft Models

  Paul Tardi, Edward Choice, Dana Masin, Thomas Redelmeier, Marcel Bally and Thomas D. Madden

  Cancer Res July 1 2000 60 (13) 3389-3393;

  
  
• Advances in Brief

  In Vivo Inhibition of Estrone Sulfatase Activity and Growth of Nitrosomethylurea-induced Mammary Tumors by 667 COUMATE

  Atul Purohit, Lawrence W. L. Woo, Barry V. L. Potter and Michael J. Reed

  Cancer Res July 1 2000 60 (13) 3394-3396;

  
  
• Advances in Brief

  Identification of New Minimally Lost Regions on 18q in Head and Neck Squamous Cell Carcinoma

  Satoru Takebayashi, Tetsuya Ogawa, Kwang-Yoon Jung, Ariege Muallem, Hiroyuki Mineta, Susan G. Fisher, Reidar Grenman and Thomas E. Carey

  Cancer Res July 1 2000 60 (13) 3397-3403;

  
  
• Advances in Brief

  Biallelic Methylation and Silencing of Mouse Aprt in Normal Kidney Cells

  Jennifer A. Rose, Phillip A. Yates, James Simpson, Jay A. Tischfield, Peter J. Stambrook and Mitchell S. Turker

  Cancer Res July 1 2000 60 (13) 3404-3408;

  
  
• Advances in Brief

  BCR-ABL Mediates Arsenic Trioxide-induced Apoptosis Independently of Its Aberrant Kinase Activity

  Elena Puccetti, Saskia Güller, Anette Orleth, Nicole Brüggenolte, Dieter Hoelzer, Oliver Gerhard Ottmann and Martin Ruthardt

  Cancer Res July 1 2000 60 (13) 3409-3413;

  
  
• Advances in Brief

  Reproductive State of Rat Mammary Gland Stroma Modulates Human Breast Cancer Cell Migration and Invasion

  Lynne T. Bemis and Pepper Schedin

  Cancer Res July 1 2000 60 (13) 3414-3418;

  
  
• Advances in Brief

  Human Carcinoembryonic Antigen Functions as a General Inhibitor of Anoikis

  Cosme Ordoñez, Robert A. Screaton, Chris Ilantzis and Clifford P. Stanners

  Cancer Res July 1 2000 60 (13) 3419-3424;

  
  
• Advances in Brief

  Loss of Cell Cycle Control Allows Selective Microtubule-active Drug-induced Bcl-2 Phosphorylation and Cytotoxicity in Autonomous Cancer Cells

  Mikhail V. Blagosklonny, Philippe C. Bishop, Robert Robey, Tito Fojo and Susan E. Bates

  Cancer Res July 1 2000 60 (13) 3425-3428;

  
  
• Advances in Brief

  Differential Expression of Cell Surface Molecules in Prostate Cancer Cells

  Alvin Y. Liu

  Cancer Res July 1 2000 60 (13) 3429-3434;

  
  
• Advances in Brief

  Heat-induced Gene Expression as a Novel Targeted Cancer Gene Therapy Strategy

  Qian Huang, Jim K. Hu, Frank Lohr, Li Zhang, Rod Braun, Jennifer Lanzen, John B. Little, Mark W. Dewhirst and Chuan-Yuan Li

  Cancer Res July 1 2000 60 (13) 3435-3439;