Table of Contents

Experimental Therapeutics

• Experimental Therapeutics

  Selective Inhibition of Vascular Endothelial Growth Factor (VEGF) Receptor 2 (KDR/Flk-1) Activity by a Monoclonal Anti-VEGF Antibody Blocks Tumor Growth in Mice

  Rolf A. Brekken, Jay P. Overholser, Victor A. Stastny, Johannes Waltenberger, John D. Minna and Philip E. Thorpe

  Cancer Res September 15 2000 60 (18) 5117-5124;

  
  
• Experimental Therapeutics

  Chemoprevention of Prostate Carcinogenesis by α-Difluoromethylornithine in TRAMP Mice

  Sanjay Gupta, Nihal Ahmad, Susan R. Marengo, Gregory T. MacLennan, Norman M. Greenberg and Hasan Mukhtar

  Cancer Res September 15 2000 60 (18) 5125-5133;

  
  
• Experimental Therapeutics

  CD99 Engagement: An Effective Therapeutic Strategy for Ewing Tumors

  Katia Scotlandi, Nicola Baldini, Vanessa Cerisano, Maria Cristina Manara, Stefania Benini, Massimo Serra, Pier-Luigi Lollini, Patrizia Nanni, Giordano Nicoletti, Ghislaine Bernard, Alain Bernard and Piero Picci

  Cancer Res September 15 2000 60 (18) 5134-5142;

  
  
• Experimental Therapeutics

  Intracranial Inhibition of Platelet-derived Growth Factor-mediated Glioblastoma Cell Growth by an Orally Active Kinase Inhibitor of the 2-Phenylaminopyrimidine Class

  Turker Kilic, John A. Alberta, Pawel R. Zdunek, Melih Acar, Palma Iannarelli, Terence O’Reilly, Elisabeth Buchdunger, Peter M. Black and Charles D. Stiles

  Cancer Res September 15 2000 60 (18) 5143-5150;

  
  
• Experimental Therapeutics

  Uroguanylin Treatment Suppresses Polyp Formation in the Apc^Min/+ Mouse and Induces Apoptosis in Human Colon Adenocarcinoma Cells via Cyclic GMP

  Kunwar Shailubhai, Helen H. Yu, Kanthasamy Karunanandaa, Joan Y. Wang, Sammy L. Eber, Yuan Wang, Nam Soo Joo, Hyun Dju Kim, Brent W. Miedema, S. Zaheer Abbas, Sekhar S. Boddupalli, Mark G. Currie and Leonard R. Forte

  Cancer Res September 15 2000 60 (18) 5151-5157;

  
  
• Experimental Therapeutics

  Human Carbonyl Reductase Overexpression in the Heart Advances the Development of Doxorubicin-induced Cardiotoxicity in Transgenic Mice

  Gerald L. Forrest, Basilio Gonzalez, William Tseng, XiuLi Li and Jeffrey Mann

  Cancer Res September 15 2000 60 (18) 5158-5164;

  
  
• Experimental Therapeutics

  Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Suppresses the Growth of Prostate Cancer Cells in Vitro and in Vivo

  Lisa M. Butler, David B. Agus, Howard I. Scher, Brian Higgins, Adam Rose, Carlos Cordon-Cardo, Howard T. Thaler, Richard A. Rifkind, Paul A. Marks and Victoria M. Richon

  Cancer Res September 15 2000 60 (18) 5165-5170;

  
  
• Experimental Therapeutics

  Taxol Mediates Serine Phosphorylation of the 66-kDa Shc Isoform

  Chia-Ping Huang Yang and Susan Band Horwitz

  Cancer Res September 15 2000 60 (18) 5171-5178;

  
  
• Experimental Therapeutics

  Noninvasive Real-Time Monitoring of Intracellular Cancer Cell Metabolism and Response to Lonidamine Treatment Using Diffusion Weighted Proton Magnetic Resonance Spectroscopy

  Yael Mardor, Ofer Kaplan, Marina Sterin, Jesus Ruiz-Cabello, Elissa Ash, Yiftach Roth, Israel Ringel and Jack S. Cohen

  Cancer Res September 15 2000 60 (18) 5179-5186;

  
  
• Experimental Therapeutics

  Direct Reversal of DNA Damage by Mutant Methyltransferase Protein Protects Mice against Dose-intensified Chemotherapy and Leads to in Vivo Selection of Hematopoietic Stem Cells

  Susanne Ragg, Meng Xu-Welliver, Jeff Bailey, Maria D’Souza, Ryan Cooper, Saurabh Chandra, Roopa Seshadri, Anthony E. Pegg and David A. Williams

  Cancer Res September 15 2000 60 (18) 5187-5195;

  
  
• Experimental Therapeutics

  Role of CYP1A1 in Modulation of Antitumor Properties of the Novel Agent 2-(4-Amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in Human Breast Cancer Cells

  Mei-Sze Chua, Eiji Kashiyama, Tracey D. Bradshaw, Sherman F. Stinson, Eileen Brantley, Edward A. Sausville and Malcolm F. G. Stevens

  Cancer Res September 15 2000 60 (18) 5196-5203;

  
  
• Experimental Therapeutics

  Pharmacological Inhibition of Phosphatidylcholine Biosynthesis Is Associated with Induction of Phosphatidylinositol Accumulation and Cytolysis of Neoplastic Cell Lines

  Robert E. Finney, Edward Nudelman, Thayer White, Stuart Bursten, Peter Klein, Laura L. Leer, Nu Wang, David Waggoner, Jack W. Singer and Robert A. Lewis

  Cancer Res September 15 2000 60 (18) 5204-5213;

  
  
• Experimental Therapeutics

  MT-21 Is a Synthetic Apoptosis Inducer That Directly Induces Cytochrome c Release from Mitochondria

  Masahiko Watabe, Kiyotaka Machida and Hiroyuki Osada

  Cancer Res September 15 2000 60 (18) 5214-5222;