Table of Contents

Advances in Brief

• Advances in Brief

  Duplication of the Mutant RET Allele in Trisomy 10 or Loss of the Wild-Type Allele in Multiple Endocrine Neoplasia Type 2-associated Pheochromocytomas

  Steve C. Huang, Christian A. Koch, Alexander O. Vortmeyer, Svetlana D. Pack, Urs D. Lichtenauer, Poonam Mannan, Irina A. Lubensky, George P. Chrousos, Robert F. Gagel, Karel Pacak and Zhengping Zhuang

  Cancer Res November 15 2000 60 (22) 6223-6226;

  
  
• Advances in Brief

  t(9;11)(p22;p15) in Acute Myeloid Leukemia Results in a Fusion between NUP98 and the Gene Encoding Transcriptional Coactivators p52 and p75-Lens Epithelium-derived Growth Factor (LEDGF)

  Harish G. Ahuja, Jianming Hong, Peter D. Aplan, Lucene Tcheurekdjian, Stephen J. Forman and Marilyn L. Slovak

  Cancer Res November 15 2000 60 (22) 6227-6229;

  
  
• Advances in Brief

  Frequent Amplification of the Telomerase Reverse Transcriptase Gene in Human Tumors

  Anju Zhang, Chengyun Zheng, Charlotta Lindvall, Mi Hou, Jessica Ekedahl, Rolf Lewensohn, Zhongqun Yan, Xiaoyan Yang, Marie Henriksson, Elisabeth Blennow, Magnus Nordenskjöld, Anders Zetterberg, Magnus Björkholm, Astrid Gruber and Dawei Xu

  Cancer Res November 15 2000 60 (22) 6230-6235;

  
  
• Advances in Brief

  TMS1, a Novel Proapoptotic Caspase Recruitment Domain Protein, Is a Target of Methylation-induced Gene Silencing in Human Breast Cancers

  Kerry E. Conway, Beth B. McConnell, Claire E. Bowring, Carlton D. Donald, Stephen T. Warren and Paula M. Vertino

  Cancer Res November 15 2000 60 (22) 6236-6242;

  
  
• Advances in Brief

  Activation of a Caspase-9-mediated Apoptotic Pathway by Subcellular Redistribution of the Novel Caspase Recruitment Domain Protein TMS1

  Beth B. McConnell and Paula M. Vertino

  Cancer Res November 15 2000 60 (22) 6243-6247;

  
  
• Advances in Brief

  Vascular Endothelial Growth Factor (VEGF) Modulation by Targeting Hypoxia-inducible Factor-1α → Hypoxia Response Element → VEGF Cascade Differentially Regulates Vascular Response and Growth Rate in Tumors

  Yoshikazu Tsuzuki, Dai Fukumura, Bert Oosthuyse, Chieko Koike, Peter Carmeliet and Rakesh K. Jain

  Cancer Res November 15 2000 60 (22) 6248-6252;

  
  
• Advances in Brief

  Complete Inhibition of Rhabdomyosarcoma Xenograft Growth and Neovascularization Requires Blockade of Both Tumor and Host Vascular Endothelial Growth Factor

  Hans-Peter Gerber, Joe Kowalski, Daniel Sherman, David A. Eberhard and Napoleone Ferrara

  Cancer Res November 15 2000 60 (22) 6253-6258;

  
  
• Advances in Brief

  The Caspase 9 Inhibitor Z-LEHD-FMK Protects Human Liver Cells while Permitting Death of Cancer Cells Exposed to Tumor Necrosis Factor-related Apoptosis-inducing Ligand

  Nesrin Özören, Kunhong Kim, Timothy F. Burns, David T. Dicker, A. David Moscioni and Wafik S. El-Deiry

  Cancer Res November 15 2000 60 (22) 6259-6265;

  
  
• Advances in Brief

  Altered Expression of Estrogen Receptor Coregulators during Human Breast Tumorigenesis

  Leigh C. Murphy, Sharon L. R. Simon, Alicia Parkes, Etienne Leygue, Helmut Dotzlaw, Linda Snell, Sandra Troup, Adewale Adeyinka and Peter H. Watson

  Cancer Res November 15 2000 60 (22) 6266-6271;

  
  
• Advances in Brief

  A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4⁺ Cytolytic T Lymphocytes

  Erwin S. Schultz, Bernard Lethé, César L. Cambiaso, Jacques Van Snick, Pascal Chaux, Jurgen Corthals, Carlo Heirman, Kris Thielemans, Thierry Boon and Pierre van der Bruggen

  Cancer Res November 15 2000 60 (22) 6272-6275;

  
  
• Advances in Brief

  Activation of the Transcription Factor Oct-1 in Response to DNA Damage

  Hongcheng Zhao, Shunqian Jin, Feiyue Fan, Wenhong Fan, Tong Tong and Qimin Zhan

  Cancer Res November 15 2000 60 (22) 6276-6280;

  
  
• Advances in Brief

  Large-Scale Serial Analysis of Gene Expression Reveals Genes Differentially Expressed in Ovarian Cancer

  Colleen D. Hough, Cheryl A. Sherman-Baust, Ellen S. Pizer, F. J. Montz, Dwight D. Im, Neil B. Rosenshein, Kathleen R. Cho, Gregory J. Riggins and Patrice J. Morin

  Cancer Res November 15 2000 60 (22) 6281-6287;

  
  
• Advances in Brief

  Frequent Association of β-Catenin and WT1 Mutations in Wilms Tumors

  Sourindra Maiti, Rita Alam, Christopher I. Amos and Vicki Huff

  Cancer Res November 15 2000 60 (22) 6288-6292;

  
  
• Advances in Brief

  Loss of Annexin 1 Correlates with Early Onset of Tumorigenesis in Esophageal and Prostate Carcinoma

  Cloud P. Paweletz, David K. Ornstein, Mark J. Roth, Verena E. Bichsel, John W. Gillespie, Valerie S. Calvert, Cathy D. Vocke, Stephen M. Hewitt, Paul H. Duray, Judi Herring, Quan-Hong Wang, Nan Hu, W. Marston Linehan, Phillip R. Taylor, Lance A. Liotta, Michael R. Emmert-Buck and Emanuel F. Petricoin III

  Cancer Res November 15 2000 60 (22) 6293-6297;

  
  
• Advances in Brief

  Thymidine Phosphorylase Induces Carcinoma Cell Oxidative Stress and Promotes Secretion of Angiogenic Factors

  Nicholas S. Brown, Adam Jones, Chisato Fujiyama, Adrian L. Harris and Roy Bicknell

  Cancer Res November 15 2000 60 (22) 6298-6302;

  
  
• Advances in Brief

  The Oncogenic Potential of the High Mobility Group Box Protein Sox3

  Yu Xia, Nancy Papalopulu, Peter K. Vogt and Jian Li

  Cancer Res November 15 2000 60 (22) 6303-6306;

  
  
• Advances in Brief

  O⁶-Benzylguanine Potentiates the Antitumor Effect of Locally Delivered Carmustine against an Intracranial Rat Glioma

  Laurence D. Rhines, Prakash Sampath, M. Eileen Dolan, Betty M. Tyler, Henry Brem and Jon Weingart

  Cancer Res November 15 2000 60 (22) 6307-6310;

  
  
• Advances in Brief

  Somatic Mutations of LKB1 and β-Catenin Genes in Gastrointestinal Polyps from Patients with Peutz-Jeghers Syndrome

  Michiko Miyaki, Takeru Iijima, Keiko Hosono, Reiko Ishii, Masamichi Yasuno, Takeo Mori, Masakazu Toi, Tsunekazu Hishima, Nobuyuki Shitara, Kazuo Tamura, Joji Utsunomiya, Naoyuki Kobayashi, Toshio Kuroki and Takeo Iwama

  Cancer Res November 15 2000 60 (22) 6311-6313;

  
  
• Advances in Brief

  Functional Analysis of Human Ornithine Decarboxylase Alleles

  Yongjun Guo, Robin B. Harris, Dan Rosson, David Boorman and Thomas G. O’Brien

  Cancer Res November 15 2000 60 (22) 6314-6317;

  
  
• Advances in Brief

  Bax Is a Transcriptional Target and Mediator of c-Myc-induced Apoptosis

  Kyran O. Mitchell, M. Stacey Ricci, Toshiyuki Miyashita, David T. Dicker, Zhaoyu Jin, John C. Reed and Wafik S. El-Deiry

  Cancer Res November 15 2000 60 (22) 6318-6325;