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Table of Contents

Review

  • Review
    p53 Antibodies in the Sera of Patients with Various Types of Cancer: A Review
    Thierry Soussi
    Cancer Res April 1 2000 60 (7) 1777-1788;

Advances in Brief

  • Advances in Brief
    Acute Doxorubicin Cardiotoxicity Involves Cardiomyocyte Apoptosis
    Olli J. Arola, Antti Saraste, Kari Pulkki, Markku Kallajoki, Martti Parvinen and Liisa-Maria Voipio-Pulkki
    Cancer Res April 1 2000 60 (7) 1789-1792;

  • Advances in Brief
    Antitumor Activity of Endostatin against Carcinogen-induced Rat Primary Mammary Tumors
    Gianpaolo Perletti, Paola Concari, Roberto Giardini, Emanuela Marras, Francesco Piccinini, Judah Folkman and Longchuan Chen
    Cancer Res April 1 2000 60 (7) 1793-1796;

  • Advances in Brief
    Gene Transfer into Brain Parenchyma Elicits Antitumor Effects
    Hassan M. Fathallah-Shaykh, Abdallah I. Kafrouni, Li-Juan Zhao, George M. Smith and James Forman
    Cancer Res April 1 2000 60 (7) 1797-1799;

  • Advances in Brief
    Relative Reciprocity of NRAS and PTEN/MMAC1 Alterations in Cutaneous Melanoma Cell Lines
    Hensin Tsao, Xue Zhang, Kianna Fowlkes and Frank G. Haluska
    Cancer Res April 1 2000 60 (7) 1800-1804;

  • Advances in Brief
    Cyclooxygenase-2, a Colorectal Cancer Nonsteroidal Anti-inflammatory Drug Target, Is Regulated by c-MYB
    Robert G. Ramsay, Annabel Friend, Yotta Vizantios, Ruth Freeman, Catherine Sicurella, Fleur Hammett, Jane Armes and Deon Venter
    Cancer Res April 1 2000 60 (7) 1805-1809;

  • Advances in Brief
    Estrogen Receptor Protects p53 from Deactivation by Human Double Minute-2
    Guozhen Liu, Janice A. Schwartz and Sam C. Brooks
    Cancer Res April 1 2000 60 (7) 1810-1814;

  • Advances in Brief
    Antibody Response to the Tumor-associated Inhibitor of Apoptosis Protein Survivin in Cancer Patients
    Jacques Rohayem, Petra Diestelkoetter, Bernd Weigle, Antje Oehmichen, Marc Schmitz, Juergen Mehlhorn, Karsten Conrad and Ernst Peter Rieber
    Cancer Res April 1 2000 60 (7) 1815-1817;

  • Advances in Brief
    Inhibitor of Apoptosis Protein hILP Undergoes Caspase-mediated Cleavage during T Lymphocyte Apoptosis
    Daniel E. Johnson, Brian R. Gastman, Eva Wieckowski, Gui-Qiang Wang, Andrew Amoscato, Scott M. Delach and Hannah Rabinowich
    Cancer Res April 1 2000 60 (7) 1818-1823;

  • Advances in Brief
    Identification of B94 (TNFAIP2) as a Potential Retinoic Acid Target Gene in Acute Promyelocytic Leukemia
    Michael E. Rusiniak, Min Yu, Douglas T. Ross, Erin C. Tolhurst and James L. Slack
    Cancer Res April 1 2000 60 (7) 1824-1829;

  • Advances in Brief
    Oncogenic Base Substitution Mutations in Circulating Leukocytes of Normal Individuals
    Vincent L. Wilson, Xiuqin Yin, Barbara Thompson, Kerry R. Wade, Jeremy P. Watkins, Qi Wei and William R. Lee
    Cancer Res April 1 2000 60 (7) 1830-1834;

  • Advances in Brief
    Hypermethylation of Multiple Genes in Pancreatic Adenocarcinoma
    Takashi Ueki, Minoru Toyota, Taylor Sohn, Charles J. Yeo, Jean-Pierre J. Issa, Ralph H. Hruban and Michael Goggins
    Cancer Res April 1 2000 60 (7) 1835-1839;

  • Advances in Brief
    A Splice Variant of the Neuron-restrictive Silencer Factor Repressor Is Expressed in Small Cell Lung Cancer: A Potential Role in Derepression of Neuroendocrine Genes and a Useful Clinical Marker
    Judy M. Coulson, Jodie L. Edgson, Penella J. Woll and John P. Quinn
    Cancer Res April 1 2000 60 (7) 1840-1844;

  • Advances in Brief
    Nuclear Factor-κB Activation Is Involved in LMP1-mediated Transformation and Tumorigenesis of Rat-1 Fibroblasts
    Zhimin He, Baozhong Xin, Xinhai Yang, Ching-ping Chan and Liang Cao
    Cancer Res April 1 2000 60 (7) 1845-1848;

Biochemistry and Biophysics

  • Biochemistry and Biophysics
    Unrepaired Fjord Region Polycyclic Aromatic Hydrocarbon-DNA Adducts in ras Codon 61 Mutational Hot Spots
    Tonko Buterin, Martin T. Hess, Natalia Luneva, Nicholas E. Geacintov, Shantu Amin, Heiko Kroth, Albrecht Seidel and Hanspeter Naegeli
    Cancer Res April 1 2000 60 (7) 1849-1856;

Carcinogenesis

  • Carcinogenesis
    Spontaneous and Nitrosourea-induced Primary Tumors of the Central Nervous System in Fischer 344 Rats Exposed to Frequency-modulated Microwave Fields
    W. Ross Adey, Craig V. Byus, Christopher D. Cain, Robert J. Higgins, Robert A. Jones, Charles J. Kean, Niels Kuster, Anne MacMurray, Robert B. Stagg and Grenith Zimmerman
    Cancer Res April 1 2000 60 (7) 1857-1863;

  • Carcinogenesis
    Chemopreventive Efficacy of Combined Piroxicam and Difluoromethylornithine Treatment of Apc Mutant Min Mouse Adenomas, and Selective Toxicity against Apc Mutant Embryos
    Russell F. Jacoby, Carolyn E. Cole, Kendra Tutsch, Michael A. Newton, Gary Kelloff, Ernest T. Hawk and Ronald A. Lubet
    Cancer Res April 1 2000 60 (7) 1864-1870;

Clinical Investigations

  • Clinical Investigations
    A Phase I Trial of the Farnesyl Transferase Inhibitor SCH66336: Evidence for Biological and Clinical Activity
    Alex A. Adjei, Charles Erlichman, Jenny N. Davis, David L. Cutler, Jeff A. Sloan, Randolph S. Marks, Lorelei J. Hanson, Phyllis A. Svingen, Pamela Atherton, W. Robert Bishop, Paul Kirschmeier and Scott H. Kaufmann
    Cancer Res April 1 2000 60 (7) 1871-1877;

Experimental Therapeutics

  • Experimental Therapeutics
    Antiangiogenic Scheduling of Chemotherapy Improves Efficacy against Experimental Drug-resistant Cancer
    Timothy Browder, Catherine E. Butterfield, Birgit M. Kräling, Bin Shi, Blair Marshall, Michael S. O’Reilly and Judah Folkman
    Cancer Res April 1 2000 60 (7) 1878-1886;

  • Experimental Therapeutics
    Adenosine-mediated Killing of Cultured Epithelial Cancer Cells
    Catherine P. Barry and Stuart E. Lind
    Cancer Res April 1 2000 60 (7) 1887-1894;

  • Experimental Therapeutics
    Antileukemic Activity of Flt3 Ligand in Murine Leukemia
    Abing Wang, Stephen E. Braun, Guru Sonpavde and Kenneth Cornetta
    Cancer Res April 1 2000 60 (7) 1895-1900;

Immunology

  • Immunology
    Anthracyclines Trigger Apoptosis of Both G0-G1 and Cycling Peripheral Blood Lymphocytes and Induce Massive Deletion of Mature T and B Cells
    Carole Ferraro, Laurence Quemeneur, Annie-France Prigent, Catherine Taverne, Jean-Pierre Revillard and Nathalie Bonnefoy-Berard
    Cancer Res April 1 2000 60 (7) 1901-1907;

  • Immunology
    Lysis of MYCN-amplified Neuroblastoma Cells by MYCN Peptide-specific Cytotoxic T Lymphocytes
    Asis K. Sarkar and Jed G. Nuchtern
    Cancer Res April 1 2000 60 (7) 1908-1913;

  • Immunology
    Aberrant Expression of Photoreceptor-specific Calcium-binding Protein (Recoverin) in Cancer Cell Lines
    Akiko Maeda, Hiroshi Ohguro, Tadao Maeda, Ikuo Wada, Noriyuki Sato, Yoshio Kuroki and Takashi Nakagawa
    Cancer Res April 1 2000 60 (7) 1914-1920;

  • Immunology
    The Human Antimouse Immunoglobulin Response and the Anti-idiotypic Network Have No Influence on Clinical Outcome in Patients with Minimal Residual Colorectal Cancer Treated with Monoclonal Antibody CO17–1A
    Rudolf Gruber, Leonardus J. M. van Haarlem, Sven O. Warnaar, Elena Holz and Gert Riethmüller
    Cancer Res April 1 2000 60 (7) 1921-1926;

  • Immunology
    Resistance to Lysis by Cytotoxic T Cells: A Dominant Effect in Metastatic Mouse Prostate Cancer Cells
    Hon-Man Lee, Terry L. Timme and Timothy C. Thompson
    Cancer Res April 1 2000 60 (7) 1927-1933;

  • Immunology
    Granulocyte Macrophage Colony-stimulating Factor and Interleukin 4 Enhance the Number and Antigen-presenting Activity of Circulating CD14+ and CD83+ Cells in Cancer Patients
    Michael D. Roth, Barbara J. Gitlitz, Sylvia M. Kiertscher, Alice N. Park, Marcy Mendenhall, Nancy Moldawer and Robert A. Figlin
    Cancer Res April 1 2000 60 (7) 1934-1941;

Molecular Biology and Genetics

  • Molecular Biology and Genetics
    VHL Alterations in Human Clear Cell Renal Cell Carcinoma: Association with Advanced Tumor Stage and a Novel Hot Spot Mutation
    Hiltrud Brauch, Gregor Weirich, Jürgen Brieger, Damjan Glavač, Heinz Rödl, Mariola Eichinger, Matthias Feurer, Eberhardt Weidt, Chutintorn Puranakanitstha, Christine Neuhaus, Sigmund Pomer, Walburgis Brenner, Peter Schirmacher, Stephan Störkel, Michael Rotter, Andrej Mašera, Nadja Gugeler and Hans-Joachim Decker
    Cancer Res April 1 2000 60 (7) 1942-1948;

  • Molecular Biology and Genetics
    High Resolution Chromosome 3p Allelotyping of Human Lung Cancer and Preneoplastic/Preinvasive Bronchial Epithelium Reveals Multiple, Discontinuous Sites of 3p Allele Loss and Three Regions of Frequent Breakpoints
    Ignacio I. Wistuba, Carmen Behrens, Arvind K. Virmani, Gina Mele, Sara Milchgrub, Luc Girard, John W. Fondon III, Harold R. Garner, Bruce McKay, Farida Latif, Michael I. Lerman, Stephen Lam, Adi F. Gazdar and John D. Minna
    Cancer Res April 1 2000 60 (7) 1949-1960;

  • Molecular Biology and Genetics
    LRP-DIT, a Putative Endocytic Receptor Gene, Is Frequently Inactivated in Non-Small Cell Lung Cancer Cell Lines
    Chun-Xiang Liu, Simone Musco, Natalia M. Lisitsina, Eva Forgacs, John D. Minna and Nikolai A. Lisitsyn
    Cancer Res April 1 2000 60 (7) 1961-1967;

  • Molecular Biology and Genetics
    Gene Amplifications Characterize Acral Melanoma and Permit the Detection of Occult Tumor Cells in the Surrounding Skin
    Boris C. Bastian, Mohammed Kashani-Sabet, Henning Hamm, Tony Godfrey, Dan H. Moore II, Eva-B. Bröcker, Philip E. LeBoit and Dan Pinkel
    Cancer Res April 1 2000 60 (7) 1968-1973;

  • Molecular Biology and Genetics
    Mutations in the XPC Gene in Families with Xeroderma Pigmentosum and Consequences at the Cell, Protein, and Transcript Levels
    Franz Chavanne, Bernard C. Broughton, Daniela Pietra, Tiziana Nardo, Alison Browitt, Alan R. Lehmann and Miria Stefanini
    Cancer Res April 1 2000 60 (7) 1974-1982;

  • Molecular Biology and Genetics
    Molecular Determinants of Apoptosis Induced by the Cytotoxic Ribonuclease Onconase: Evidence for Cytotoxic Mechanisms Different from Inhibition of Protein Synthesis
    Mihail S. Iordanov, Olga P. Ryabinina, John Wong, Thanh-Hoai Dinh, Dianne L. Newton, Susanna M. Rybak and Bruce E. Magun
    Cancer Res April 1 2000 60 (7) 1983-1994;

Tumor Biology

  • Tumor Biology
    Expression of Metallothionein II in Intestinal Metaplasia, Dysplasia, and Gastric Cancer
    Matthias P. A. Ebert, Thomas Günther, Juliane Hoffmann, Jun Yu, Stephan Miehlke, Hans U. Schulz, Albert Roessner, Murray Korc and Peter Malfertheiner
    Cancer Res April 1 2000 60 (7) 1995-2001;

  • Tumor Biology
    Loss of Expression of Dpc4 in Pancreatic Intraepithelial Neoplasia: Evidence That DPC4 Inactivation Occurs Late in Neoplastic Progression
    Robb E. Wilentz, Christine A. Iacobuzio-Donahue, Pedram Argani, Denis M. McCarthy, Jennifer L. Parsons, Charles J. Yeo, Scott E. Kern and Ralph H. Hruban
    Cancer Res April 1 2000 60 (7) 2002-2006;

  • Tumor Biology
    Insulin-like Growth Factor-I Protects Colon Cancer Cells from Death Factor-induced Apoptosis by Potentiating Tumor Necrosis Factor α-induced Mitogen-activated Protein Kinase and Nuclear Factor κB Signaling Pathways
    Maryse M. Remacle-Bonnet, Françoise L. Garrouste, Sara Heller, Frédéric André, Jacques L. Marvaldi and Gilbert J. Pommier
    Cancer Res April 1 2000 60 (7) 2007-2017;

  • Tumor Biology
    Detection of Hypoxia in Human Squamous Cell Carcinoma by EF5 Binding
    Sydney M. Evans, Stephen Hahn, Deirdre R. Pook, W. Timothy Jenkins, Ara A. Chalian, Paul Zhang, Craig Stevens, Randall Weber, Gregory Weinstein, Ivor Benjamin, Natasha Mirza, Mark Morgan, Steven Rubin, W. Gillies McKenna, Edith M. Lord and Cameron J. Koch
    Cancer Res April 1 2000 60 (7) 2018-2024;

  • Tumor Biology
    S-phase Arrest and Apoptosis Induced in Normal Mammary Epithelial Cells by a Novel Retinoid
    Yuxiang Zhang, Arun K. Rishi, Marcia I. Dawson, Rainbow Tschang, Lulu Farhana, Madanamohan Boyanapalli, Uwe Reichert, Braham Shroot, Eric C. Van Buren and Joseph A. Fontana
    Cancer Res April 1 2000 60 (7) 2025-2032;

  • Tumor Biology
    Fibrinogen Assembly, Secretion, and Deposition into Extracellular Matrix by MCF-7 Human Breast Carcinoma Cells
    Brian J. Rybarczyk and Patricia J. Simpson-Haidaris
    Cancer Res April 1 2000 60 (7) 2033-2039;

  • Tumor Biology
    1,25-Dihydroxyvitamin D3 and All-trans-Retinoic Acid Sensitize Breast Cancer Cells to Chemotherapy-induced Cell Death
    Qin Wang, Wen Yang, Myrna S. Uytingco, Sylvia Christakos and Robert Wieder
    Cancer Res April 1 2000 60 (7) 2040-2048;

  • Tumor Biology
    BCR-ABL Tyrosine Kinase Activity Regulates the Expression of Multiple Genes Implicated in the Pathogenesis of Chronic Myeloid Leukemia
    Michael W. N. Deininger, Sara Vieira, Rezzeline Mendiola, Beate Schultheis, John M. Goldman and Junia V. Melo
    Cancer Res April 1 2000 60 (7) 2049-2055;

  • Tumor Biology
    Glucocorticoid Receptor Gene Mutations in Leukemic Cells Acquired in Vitro and in Vivo
    Andrew G. Hillmann, Jyoti Ramdas, Kirsi Multanen, Michael R. Norman and Jeffrey M. Harmon
    Cancer Res April 1 2000 60 (7) 2056-2062;

Erratum

  • Erratum
    J. Jongsma et al., Cancer Res., 60: 741–748, 2000
    Cancer Res April 1 2000 60 (7) 2064-2064;

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April 2000
Volume 60, Issue 7
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Cancer Research Online ISSN: 1538-7445
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