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Table of Contents

Advances in Brief

  • Advances in Brief
    Hydrogen Peroxide Mediates Activation of Nuclear Factor of Activated T Cells (NFAT) by Nickel Subsulfide
    Chuanshu Huang, Jingxia Li, Max Costa, Zhuo Zhang, Stephen S. Leonard, Vincent Castranova, Val Vallyathan, Gong Ju and Xianglin Shi
    Cancer Res November 15 2001 61 (22) 8051-8057;

  • Advances in Brief
    In Situ Expression of Interleukin-4 (IL-4) Receptors in Human Brain Tumors and Cytotoxicity of a Recombinant IL-4 Cytotoxin in Primary Glioblastoma Cell Cultures
    Bharat H. Joshi, Pamela Leland, Anthony Asher, Richard A. Prayson, Frederick Varricchio and Raj K. Puri
    Cancer Res November 15 2001 61 (22) 8058-8061;

  • Advances in Brief
    Destabilization of CHK2 by a Missense Mutation Associated with Li-Fraumeni Syndrome
    Sean Bong Lee, Sang Hyon Kim, Daphne W. Bell, Doke C. R. Wahrer, Taryn A. Schiripo, Melissa M. Jorczak, Dennis C. Sgroi, Judy E. Garber, Frederick P. Li, Kim E. Nichols, Jenny M. Varley, Andrew K. Godwin, Kristen M. Shannon, Ed Harlow and Daniel A. Haber
    Cancer Res November 15 2001 61 (22) 8062-8067;

  • Advances in Brief
    WWOX, the FRA16D Gene, Behaves as a Suppressor of Tumor Growth
    Andrzej K. Bednarek, Catherine L. Keck-Waggoner, Rachael L. Daniel, Kendra J. Laflin, P. Leif Bergsagel, Kaoru Kiguchi, Andrew J. Brenner and C. Marcelo Aldaz
    Cancer Res November 15 2001 61 (22) 8068-8073;

  • Advances in Brief
    Cytoplasmic Localization of the Oncogenic Protein Ski in Human Cutaneous Melanomas in Vivo
    Jon A. Reed, Elise Bales, Weidong Xu, Nihal A. Okan, Debdutta Bandyopadhyay and Estela E. Medrano
    Cancer Res November 15 2001 61 (22) 8074-8078;

  • Advances in Brief
    LYVE-1 Is Not Restricted to the Lymph Vessels
    Carla Mouta Carreira, Selim M. Nasser, Emmanuelle di Tomaso, Timothy P. Padera, Yves Boucher, Stanislav I. Tomarev and Rakesh K. Jain
    Cancer Res November 15 2001 61 (22) 8079-8084;

  • Advances in Brief
    β-Catenin Expression Is Altered in Human Colonic Aberrant Crypt Foci
    Xing Pei Hao, Thomas G. Pretlow, J. Sunil Rao and Theresa P. Pretlow
    Cancer Res November 15 2001 61 (22) 8085-8088;

  • Advances in Brief
    Expression of the Invasion Factor Laminin γ2 in Colorectal Carcinomas Is Regulated by β-Catenin
    Falk Hlubek, Andreas Jung, Nicole Kotzor, Thomas Kirchner and Thomas Brabletz
    Cancer Res November 15 2001 61 (22) 8089-8093;

  • Advances in Brief
    Hypermethylation in Human Cancers of the RIZ1 Tumor Suppressor Gene, a Member of a Histone/Protein Methyltransferase Superfamily
    Yong Du, Tobias Carling, Wei Fang, Zhe Piao, Jin-Chuan Sheu and Shi Huang
    Cancer Res November 15 2001 61 (22) 8094-8099;

  • Advances in Brief
    Mining the Melanosome for Tumor Vaccine Targets
    Christopher E. Touloukian, Wolfgang W. Leitner, Paul F. Robbins, Steven A. Rosenberg and Nicholas P. Restifo
    Cancer Res November 15 2001 61 (22) 8100-8104;

  • Advances in Brief
    Comparative Analysis of Necrotic and Apoptotic Tumor Cells As a Source of Antigen(s) in Dendritic Cell-based Immunization
    Yoshihito Kotera, Koichi Shimizu and James J. Mulé
    Cancer Res November 15 2001 61 (22) 8105-8109;

  • Advances in Brief
    Modulation of the Immune Response by Systemic Targeting of Antigens to Lymph Nodes
    Martin Trepel, Wadih Arap and Renata Pasqualini
    Cancer Res November 15 2001 61 (22) 8110-8112;

  • Advances in Brief
    O6-Methylguanine-DNA Methyltransferase Promoter Hypermethylation Shifts the p53 Mutational Spectrum in Non-Small Cell Lung Cancer
    Patrick Wolf, Ying Chuan Hu, Kara Doffek, David Sidransky and Steven A. Ahrendt
    Cancer Res November 15 2001 61 (22) 8113-8117;

  • Advances in Brief
    KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors
    Brian P. Rubin, Samuel Singer, Connie Tsao, Anette Duensing, Marcia L. Lux, Robert Ruiz, Michele K. Hibbard, Chang-Jie Chen, Sheng Xiao, David A. Tuveson, George D. Demetri, Christopher D. M. Fletcher and Jonathan A. Fletcher
    Cancer Res November 15 2001 61 (22) 8118-8121;

  • Advances in Brief
    T-Cell Receptor γ Chain Alternate Reading Frame Protein (TARP) Expression in Prostate Cancer Cells Leads to an Increased Growth Rate and Induction of Caveolins and Amphiregulin
    Curt D. Wolfgang, Magnus Essand, Byungkook Lee and Ira Pastan
    Cancer Res November 15 2001 61 (22) 8122-8126;

Carcinogenesis

  • Carcinogenesis
    Induction of Antitumor Immunity via Intratumoral Tetra-Costimulator Protein Transfer
    Guoxing Zheng, Aoshuang Chen, Raymond E. Sterner, Paul J. Zhang, Tao Pan, Nadya Kiyatkin and Mark L. Tykocinski
    Cancer Res November 15 2001 61 (22) 8127-8134;

  • Carcinogenesis
    Malignant Transformation in a Nontumorigenic Human Prostatic Epithelial Cell Line
    Simon W. Hayward, Yuzhuo Wang, Mei Cao, Yun Kit Hom, Baohui Zhang, Gary D. Grossfeld, Daniel Sudilovsky and Gerald R. Cunha
    Cancer Res November 15 2001 61 (22) 8135-8142;

  • Carcinogenesis
    The Consequences of Chromosomal Aneuploidy on Gene Expression Profiles in a Cell Line Model for Prostate Carcinogenesis
    John L. Phillips, Simon W. Hayward, Yuzhuo Wang, James Vasselli, Christian Pavlovich, Hesed Padilla-Nash, John R. Pezullo, B. Michael Ghadimi, Gary D. Grossfeld, Alexandra Rivera, W. Marston Linehan, Gerald R. Cunha and Thomas Ried
    Cancer Res November 15 2001 61 (22) 8143-8149;

  • Carcinogenesis
    Induction of Melanoma in Murine Macrophage Inflammatory Protein 2 Transgenic Mice Heterozygous for Inhibitor of Kinase/Alternate Reading Frame
    Jinming Yang, Jing Luan, Yingchun Yu, Cunxi Li, Ronald A. DePinho, Lynda Chin and Ann Richmond
    Cancer Res November 15 2001 61 (22) 8150-8157;

  • Carcinogenesis
    UV-induced DNA Damage and Mutations in Hupki (Human p53 Knock-in) Mice Recapitulate p53 Hotspot Alterations in Sun-exposed Human Skin
    Jun-Li Luo, Wei-Min Tong, Jung-Hoon Yoon, Manfred Hergenhahn, Riita Koomagi, Qin Yang, Dominique Galendo, Gerd P. Pfeifer, Zhao-Qi Wang and Monica Hollstein
    Cancer Res November 15 2001 61 (22) 8158-8163;

  • Carcinogenesis
    A New Selective and Potent Inhibitor of Human Cytochrome P450 1B1 and Its Application to Antimutagenesis
    Young-Jin Chun, Sanghee Kim, Donghak Kim, Sang-Kwang Lee and F. Peter Guengerich
    Cancer Res November 15 2001 61 (22) 8164-8170;

Experimental Therapeutics

  • Experimental Therapeutics
    Inhibition of Angiogenesis-driven Kaposi’s Sarcoma Tumor Growth in Nude Mice by Oral N-Acetylcysteine
    Adriana Albini, Monica Morini, Francesco D’Agostini, Nicoletta Ferrari, Francesco Campelli, Giuseppe Arena, Douglas M. Noonan, Carlo Pesce and Silvio De Flora
    Cancer Res November 15 2001 61 (22) 8171-8178;

  • Experimental Therapeutics
    Quantitative Imaging and Microlocalization of Boron-10 in Brain Tumors and Infiltrating Tumor Cells by SIMS Ion Microscopy
    Duane R. Smith, Subhash Chandra, Rolf F. Barth, Weilian Yang, Darrel D. Joel and Jeffrey A. Coderre
    Cancer Res November 15 2001 61 (22) 8179-8187;

  • Experimental Therapeutics
    A Genetically Engineered Influenza A Virus with ras-Dependent Oncolytic Properties
    Michael Bergmann, Ingrid Romirer, Monika Sachet, Reinhard Fleischhacker, Adolfo García-Sastre, Peter Palese, Klaus Wolff, Hubert Pehamberger, Raimund Jakesz and Thomas Muster
    Cancer Res November 15 2001 61 (22) 8188-8193;

  • Experimental Therapeutics
    Molecular Basis for the Synergistic Interaction of Adriamycin with the Formaldehyde-releasing Prodrug Pivaloyloxymethyl Butyrate (AN-9)
    Suzanne M. Cutts, Ada Rephaeli, Abraham Nudelman, Inesa Hmelnitsky and Don R. Phillips
    Cancer Res November 15 2001 61 (22) 8194-8202;

  • Experimental Therapeutics
    The Phosphatidylinositide 3′-Kinase/Akt Survival Pathway Is a Target for the Anticancer and Radiosensitizing Agent PKC412, an Inhibitor of Protein Kinase C
    Angela Tenzer, Daniel Zingg, Sonia Rocha, Brian Hemmings, Doriano Fabbro, Christoph Glanzmann, P. August Schubiger, Stephan Bodis and Martin Pruschy
    Cancer Res November 15 2001 61 (22) 8203-8210;

  • Experimental Therapeutics
    Radiosensitization of p53 Mutant Cells by PD0166285, a Novel G2 Checkpoint Abrogator
    Yuli Wang, Jun Li, Robert N. Booher, Alan Kraker, Theodore Lawrence, Wilbur R. Leopold and Yi Sun
    Cancer Res November 15 2001 61 (22) 8211-8217;

Immunology

  • Immunology
    Phases of Apoptosis of Melanoma Cells, but not of Normal Melanocytes, Differently Affect Maturation of Myeloid Dendritic Cells
    Gabriella Pietra, Roberta Mortarini, Giorgio Parmiani and Andrea Anichini
    Cancer Res November 15 2001 61 (22) 8218-8226;

  • Immunology
    Immunization with Wild-Type p53 Gene Sequences Coadministered with Flt3 Ligand Induces an Antigen-specific Type 1 T-Cell Response
    Prahlad Parajuli, Vladimir Pisarev, Jennifer Sublet, Amy Steffel, Michelle Varney, Rakesh Singh, Drake LaFace and James E. Talmadge
    Cancer Res November 15 2001 61 (22) 8227-8234;

Molecular Biology and Genetics

  • Molecular Biology and Genetics
    New Amplified and Highly Expressed Genes Discovered in the ERBB2 Amplicon in Breast Cancer by cDNA Microarrays
    Päivikki Kauraniemi, Maarit Bärlund, Outi Monni and Anne Kallioniemi
    Cancer Res November 15 2001 61 (22) 8235-8240;

  • Molecular Biology and Genetics
    Identification of Cytogenetic Subgroups and Karyotypic Pathways in Transitional Cell Carcinoma
    Mattias Höglund, Torbjörn Säll, Sverre Heim, Felix Mitelman, Nils Mandahl and Imad Fadl-Elmula
    Cancer Res November 15 2001 61 (22) 8241-8246;

  • Molecular Biology and Genetics
    Diverse Mechanisms of β-Catenin Deregulation in Ovarian Endometrioid Adenocarcinomas
    Rong Wu, Yali Zhai, Eric R. Fearon and Kathleen R. Cho
    Cancer Res November 15 2001 61 (22) 8247-8255;

  • Molecular Biology and Genetics
    p53R2-dependent Pathway for DNA Synthesis in a p53-regulated Cell Cycle Checkpoint
    Tatsuya Yamaguchi, Koichi Matsuda, Yoji Sagiya, Manabu Iwadate, Masayuki A. Fujino, Yusuke Nakamura and Hirofumi Arakawa
    Cancer Res November 15 2001 61 (22) 8256-8262;

  • Molecular Biology and Genetics
    Independent Amplification of Two Gene Clusters on Chromosome 4 in Rat Endometrial Cancer
    Anna Walentinsson, Khalil Helou, Ville Wallenius, Hans J. Hedrich, Claude Szpirer and Göran Levan
    Cancer Res November 15 2001 61 (22) 8263-8273;

  • Molecular Biology and Genetics
    Intrachromosomal Genomic Instability in Human Sporadic Colorectal Cancer Measured by Genome-Wide Allelotyping and Inter-(Simple Sequence Repeat) PCR
    Garth R. Anderson, Bruce M. Brenner, Helen Swede, Neng Chen, W. Michael Henry, Jeffrey M. Conroy, Matthew J. Karpenko, Jean-Pierre Issa, Jeremy D. Bartos, Joslyn K. Brunelle, Gerald P. Jahreis, Morton S. Kahlenberg, Mark Basik, Sheila Sait, Miguel A. Rodriguez-Bigas, Norma J. Nowak, Nicholas J. Petrelli, Thomas B. Shows and Daniel L. Stoler
    Cancer Res November 15 2001 61 (22) 8274-8283;

  • Molecular Biology and Genetics
    p16INK4a Lesions Are Common, Early Abnormalities that Undergo Clonal Expansion in Barrett’s Metaplastic Epithelium
    David J. Wong, Thomas G. Paulson, Laura J. Prevo, Patricia C. Galipeau, Gary Longton, Patricia L. Blount and Brian J. Reid
    Cancer Res November 15 2001 61 (22) 8284-8289;

  • Molecular Biology and Genetics
    Loss of DNA Mismatch Repair Imparts Defective cdc2 Signaling and G2 Arrest Responses without Altering Survival after Ionizing Radiation
    Tao Yan, Jane E. Schupp, Hwa-shin Hwang, Mark W. Wagner, Suzanne E. Berry, Sue Strickfaden, Martina L. Veigl, W. David Sedwick, David A. Boothman and Timothy J. Kinsella
    Cancer Res November 15 2001 61 (22) 8290-8297;

Tumor Biology

  • Tumor Biology
    Transgenic Polyoma Middle-T Mice Model Premalignant Mammary Disease
    Jeannie E. Maglione, Drew Moghanaki, Lawrence J. T. Young, Cathyryne K. Manner, Lesley G. Ellies, Sasha O. Joseph, Benjamin Nicholson, Robert D. Cardiff and Carol L. MacLeod
    Cancer Res November 15 2001 61 (22) 8298-8305;

  • Tumor Biology
    Transforming Growth Factor-β1 Increases Survival of Human Melanoma through Stroma Remodeling
    Carola Berking, Richelle Takemoto, Helmut Schaider, Louise Showe, Kapaettu Satyamoorthy, Paul Robbins and Meenhard Herlyn
    Cancer Res November 15 2001 61 (22) 8306-8316;

  • Tumor Biology
    Increased p53 Mutation Frequency during Tumor Progression—Results from a Breast Cancer Cohort
    Torbjörn Norberg, Sigrid Klaar, Gunilla Kärf, Hans Nordgren, Lars Holmberg and Jonas Bergh
    Cancer Res November 15 2001 61 (22) 8317-8321;

  • Tumor Biology
    Induction of Glucose-regulated Protein 78 by Chronic Hypoxia in Human Gastric Tumor Cells through a Protein Kinase C-ε/ERK/AP-1 Signaling Cascade
    Min Sup Song, Yong Keun Park, Je-Ho Lee and Kyoungsook Park
    Cancer Res November 15 2001 61 (22) 8322-8330;

  • Tumor Biology
    Heterogeneous Transforming Growth Factor (TGF)-β Unresponsiveness and Loss of TGF-β Receptor Type II Expression Caused by Histone Deacetylation in Lung Cancer Cell Lines
    Hirotaka Osada, Yoshio Tatematsu, Akira Masuda, Toshiko Saito, Miyabi Sugiyama, Kiyoshi Yanagisawa and Takashi Takahashi
    Cancer Res November 15 2001 61 (22) 8331-8339;

  • Tumor Biology
    Endothelin-1 Induces Tumor Proteinase Activation and Invasiveness of Ovarian Carcinoma Cells
    Laura Rosanò, Marco Varmi, Debora Salani, Valeriana Di Castro, Francesca Spinella, Pier Giorgio Natali and Anna Bagnato
    Cancer Res November 15 2001 61 (22) 8340-8346;

Letters to the Editor

  • Letters to the Editor
    Correspondence re: J. W. Baish and R. K. Jain, Fractals and Cancer. Cancer Res., 60: 3683–3688, 2000.
    Hsiao-Wen Chung and Hsiao-Jen Chung
    Cancer Res November 15 2001 61 (22) 8347-8348;

  • Letters to the Editor
    TβR-I(6A) Polymorphism Is not a Tumor Susceptibility Allele in Macedonian Colorectal Cancer Patients Correspondence re: B. Pasche et al. Type I TβR-I(6A) Is a Candidate Tumor Susceptibility Allele. Cancer Res., 58: 2727–2732, 1998.
    Ana-Marija Stefanovska, Georgi D. Efremov, Aleksandar J. Dimovski, Djingis Jasar, Gjorgi Zografski, Toni Josifovski, Milco Panovski, Renata Jankova and Mirko Spiroski
    Cancer Res November 15 2001 61 (22) 8351-8351;

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Cancer Research: 61 (22)
November 2001
Volume 61, Issue 22
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Issue Highlights

  • Destabilization of CHK2 by a Missense Mutation Associated with Li-Fraumeni Syndrome
  • KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors
  • Transgenic Polyoma Middle-T Mice Model Premalignant Mammary Disease

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  • SHP2 in Macrophages and Tumor Immunosuppression
  • LDtrait: Identify Phenotype Associations in LD
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Cancer Research Online ISSN: 1538-7445
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