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Table of Contents

Advances in Brief

  • Advances in Brief
    Inhibition of Histone Deacetylase Activity by Trichostatin A Modulates Gene Expression during Mouse Embryogenesis without Apparent Toxicity
    Clara Nervi, Ugo Borello, Francesco Fazi, Viviana Buffa, Pier Giuseppe Pelicci and Giulio Cossu
    Cancer Res February 2 2001 61 (4) 1247-1249;

  • Advances in Brief
    The ZNF217 Gene Amplified in Breast Cancers Promotes Immortalization of Human Mammary Epithelial Cells
    Genevieve H. Nonet, Martha R. Stampfer, Koei Chin, Joe W. Gray, Colin C. Collins and Paul Yaswen
    Cancer Res February 2 2001 61 (4) 1250-1254;

  • Advances in Brief
    The Effects of Angiopoietin-1 and -2 on Tumor Growth and Angiogenesis in Human Colon Cancer
    Syed A. Ahmad, Wenbiao Liu, Young D. Jung, Fan Fan, Michael Wilson, Niels Reinmuth, Raymond M. Shaheen, Corazon D. Bucana and Lee M. Ellis
    Cancer Res February 2 2001 61 (4) 1255-1259;

  • Advances in Brief
    Apoptosis Induction by the Photosensitizer Verteporfin: Identification of Mitochondrial Adenine Nucleotide Translocator as a Critical Target
    Anne-Sophie Belzacq, Etienne Jacotot, Helena L. A. Vieira, Dominique Mistro, David J. Granville, Zhihua Xie, John C. Reed, Guido Kroemer and Catherine Brenner
    Cancer Res February 2 2001 61 (4) 1260-1264;

  • Advances in Brief
    The Fibroblast Growth Factor Receptor 3 (FGFR3) Mutation Is a Strong Indicator of Superficial Bladder Cancer with Low Recurrence Rate
    Bas W. G. van Rhijn, Irene Lurkin, François Radvanyi, Wim J. Kirkels, Theodorus H. van der Kwast and Ellen C. Zwarthoff
    Cancer Res February 2 2001 61 (4) 1265-1268;

  • Advances in Brief
    Age-associated Risk of Cancer among Individuals with N-Acetyltransferase 2 (NAT2) Mutations and Mutations in DNA Mismatch Repair Genes
    Marsha L. Frazier, Frederick T. O’Donnell, Shouming Kong, Xiangjun Gu, Imelda Campos, Rajyalakshmi Luthra, Patrick M. Lynch and Christopher I. Amos
    Cancer Res February 2 2001 61 (4) 1269-1271;

  • Advances in Brief
    Hydroxamate-Type Matrix Metalloproteinase Inhibitor Batimastat Promotes Liver Metastasis
    Achim Krüger, Rita Soeltl, Igor Sopov, Charlotte Kopitz, Matthias Arlt, Viktor Magdolen, Nadia Harbeck, Bernd Gänsbacher and Manfred Schmitt
    Cancer Res February 2 2001 61 (4) 1272-1275;

  • Advances in Brief
    Coexpression of the Partial Androgen Receptor Enhances the Efficacy of Prostate-specific Antigen Promoter-driven Suicide Gene Therapy for Prostate Cancer Cells at Low Testosterone Concentrations
    Satoshi Suzuki, Takushi Tadakuma, Tomohiko Asano and Masamichi Hayakawa
    Cancer Res February 2 2001 61 (4) 1276-1279;

  • Advances in Brief
    CEP1612, a Dipeptidyl Proteasome Inhibitor, Induces p21WAF1 and p27KIP1 Expression and Apoptosis and Inhibits the Growth of the Human Lung Adenocarcinoma A-549 in Nude Mice
    Jiazhi Sun, Sangkil Nam, Chang-Sun Lee, Benyi Li, Domenico Coppola, Andrew D. Hamilton, Q. Ping Dou and Saïd M. Sebti
    Cancer Res February 2 2001 61 (4) 1280-1284;

  • Advances in Brief
    Cytokine Gene Expression in Neoplastic B Cells from Human Mantle Cell, Follicular, and Marginal Zone Lymphomas and in Their Postulated Normal Counterparts
    Irma Airoldi, Roberta Guglielmino, Fabio Ghiotto, Anna Corcione, Paola Facchetti, Mauro Truini and Vito Pistoia
    Cancer Res February 2 2001 61 (4) 1285-1290;

  • Advances in Brief
    Ovarian Epithelial Cell Lineage-specific Gene Expression Using the Promoter of a Retrovirus-like Element
    Muthu Selvakumaran, Rudi Bao, Anne P. G. Crijns, Denise C. Connolly, Jillian K. Weinstein and Thomas C. Hamilton
    Cancer Res February 2 2001 61 (4) 1291-1295;

  • Advances in Brief
    Invasiveness of Cutaneous Malignant Melanoma Is Influenced by Matrix Metalloproteinase 1 Gene Polymorphism
    Shu Ye, Sahar Dhillon, Steven J. Turner, Adrian C. Bateman, Jeffrey M. Theaker, Ruth M. Pickering, Ian Day and W. Martin Howell
    Cancer Res February 2 2001 61 (4) 1296-1298;

  • Advances in Brief
    Detection of Mitochondrial DNA Mutations in Pancreatic Cancer Offers a “Mass”-ive Advantage over Detection of Nuclear DNA Mutations
    Jessa B. Jones, Jason J. Song, Paula M. Hempen, Giovanni Parmigiani, Ralph H. Hruban and Scott E. Kern
    Cancer Res February 2 2001 61 (4) 1299-1304;

  • Advances in Brief
    Epistatic Interactions between Skin Tumor Modifier Loci in Interspecific (spretus/musculus) Backcross Mice
    Hiroki Nagase, Jian-Hua Mao, John P. de Koning, Tomoe Minami and Allan Balmain
    Cancer Res February 2 2001 61 (4) 1305-1308;

  • Advances in Brief
    Chromosomal Alterations in Lung Adenocarcinoma from Smokers and Nonsmokers
    Montserrat Sanchez-Cespedes, Steven A. Ahrendt, Steven Piantadosi, Rafael Rosell, Maria Monzo, Li Wu, William H. Westra, Steven C. Yang, Jin Jen and David Sidransky
    Cancer Res February 2 2001 61 (4) 1309-1313;

  • Advances in Brief
    Resistance to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in Neuroblastoma Cells Correlates with a Loss of Caspase-8 Expression
    Angelika Eggert, Michael A. Grotzer, Tycho J. Zuzak, Barbara R. Wiewrodt, Ruth Ho, Naohiko Ikegaki and Garrett M. Brodeur
    Cancer Res February 2 2001 61 (4) 1314-1319;

  • Advances in Brief
    Breast Stroma Plays a Dominant Regulatory Role in Breast Epithelial Growth and Differentiation: Implications for Tumor Development and Progression
    Malathy P. V. Shekhar, Jill Werdell, Steve J. Santner, Robert J. Pauley and Larry Tait
    Cancer Res February 2 2001 61 (4) 1320-1326;

  • Advances in Brief
    DNA Methyltransferase Inhibition Enhances Apoptosis Induced by Histone Deacetylase Inhibitors
    Wei-Guo Zhu, Romola R. Lakshmanan, Matthew D. Beal and Gregory A. Otterson
    Cancer Res February 2 2001 61 (4) 1327-1333;

  • Advances in Brief
    Global Effects of Anchorage on Gene Expression during Mammary Carcinoma Cell Growth Reveal Role of Tumor Necrosis Factor-related Apoptosis-inducing Ligand in Anoikis
    Gary S. Goldberg, Zhaoyu Jin, Hitoshi Ichikawa, Akihiro Naito, Misao Ohki, Wafik S. El-Deiry and Hiroyuki Tsuda
    Cancer Res February 2 2001 61 (4) 1334-1337;

  • Advances in Brief
    Down-Regulation of Promoter I.3 Activity of the Human Aromatase Gene in Breast Tissue by Zinc-finger Protein, Snail (SnaH)
    Tomoharu Okubo, Thong K. Truong, Bin Yu, Toru Itoh, Jin Zhao, Baiba Grube, Dujin Zhou and Shiuan Chen
    Cancer Res February 2 2001 61 (4) 1338-1346;

  • Advances in Brief
    Phosphorylation- and SKP1-independent in Vitro Ubiquitination of E2F1 by Multiple ROC-Cullin Ligases
    Tomohiko Ohta and Yue Xiong
    Cancer Res February 2 2001 61 (4) 1347-1353;

  • Advances in Brief
    Modulation of Nucleotide Excision Repair Capacity by XPD Polymorphisms in Lung Cancer Patients
    Margaret R. Spitz, Xifeng Wu, Yunfei Wang, Li-E Wang, Sanjay Shete, Christopher I. Amos, Zhaozheng Guo, Lei Lei, Harvey Mohrenweiser and Qingyi Wei
    Cancer Res February 2 2001 61 (4) 1354-1357;

  • Advances in Brief
    Erythropoietin Restores the Anemia-induced Reduction in Cyclophosphamide Cytotoxicity in Rat Tumors
    Oliver Thews, Debra K. Kelleher and Peter Vaupel
    Cancer Res February 2 2001 61 (4) 1358-1361;

Biochemistry and Biophysics

  • Biochemistry and Biophysics
    Altered Profiles in Nuclear Matrix Proteins Associated with DNA in Situ during Progression of Breast Cancer Cells
    Virginia A. Spencer, Shanti K. Samuel and James R. Davie
    Cancer Res February 2 2001 61 (4) 1362-1366;

  • Biochemistry and Biophysics
    Up-Regulation of Urokinase-Type Plasminogen Activator by Insulin-like Growth Factor-I Depends upon Phosphatidylinositol-3 Kinase and Mitogen-activated Protein Kinase Kinase
    Sandra E. Dunn, Johann V. Torres, Jennifer S. Oh, David M. Cykert and J. Carl Barrett
    Cancer Res February 2 2001 61 (4) 1367-1374;

Carcinogenesis

  • Carcinogenesis
    Elevated Protein Kinase C βII Is an Early Promotive Event in Colon Carcinogenesis
    Yesim Gökmen-Polar, Nicole R. Murray, Marco A. Velasco, Zoran Gatalica and Alan P. Fields
    Cancer Res February 2 2001 61 (4) 1375-1381;

  • Carcinogenesis
    Frequent Mutations of Fas Gene in Thyroid Lymphoma
    Tetsuya Takakuwa, Zhiming Dong, Hitoshi Takayama, Fumio Matsuzuka, Shigekazu Nagata and Katsuyuki Aozasa
    Cancer Res February 2 2001 61 (4) 1382-1385;

  • Carcinogenesis
    Suppression of Tumor Cell Growth Both in Nude Mice and in Culture by n-3 Polyunsaturated Fatty Acids: Mediation through Cyclooxygenase-independent Pathways
    Mary D. Boudreau, Kyung Hee Sohn, Sang Hoon Rhee, Sam W. Lee, Jay D. Hunt and Daniel H. Hwang
    Cancer Res February 2 2001 61 (4) 1386-1391;

  • Carcinogenesis
    Involvement of Mammalian MLH1 in the Apoptotic Response to Peroxide-induced Oxidative Stress
    Rebecca A. Hardman, Cynthia A. Afshari and J. Carl Barrett
    Cancer Res February 2 2001 61 (4) 1392-1397;

  • Carcinogenesis
    Crkl Enhances Leukemogenesis in BCR/ABL P190 Transgenic Mice
    Bianca Hemmeryckx, Arnoud van Wijk, Anja Reichert, Vesa Kaartinen, Ron de Jong, Paul K. Pattengale, Ignacio Gonzalez-Gomez, John Groffen and Nora Heisterkamp
    Cancer Res February 2 2001 61 (4) 1398-1405;

Clinical Investigations

  • Clinical Investigations
    Increased Gastric Epithelial Cell Apoptosis Associated with Colonization with cagA+ Helicobacter pylori Strains
    Steven F. Moss, Emilia Mia Sordillo, Abdalrahman M. Abdalla, Vladimir Makarov, Zoltan Hanzely, Guillermo I. Perez-Perez, Martin J. Blaser and Peter R. Holt
    Cancer Res February 2 2001 61 (4) 1406-1411;

  • Clinical Investigations
    P-Glycoprotein and Multidrug Resistance-related Protein Expressions in Relation to Technetium-99m Methoxyisobutylisonitrile Scintimammography Findings
    Chia-Hung Kao, Shih-Chuan Tsai, Tse-Jia Liu, Yung-Jen Ho, Jhi-Joung Wang, Shung-Tai Ho and Sheng-Ping ChangLai
    Cancer Res February 2 2001 61 (4) 1412-1414;

  • Clinical Investigations
    The COOH-Terminal Src Kinase Csk Is a Tumor Antigen in Human Carcinoma
    Christine Bénistant, Jean-François Bourgaux, Heliette Chapuis, Nicolas Mottet, Serge Roche and Jean-Pierre Bali
    Cancer Res February 2 2001 61 (4) 1415-1420;

  • Clinical Investigations
    Thymidine Kinase and Thymidylate Synthase in Advanced Breast Cancer: Response to Tamoxifen and Chemotherapy
    John A. Foekens, Sylvie Romain, Maxime P. Look, Pierre-Marie Martin and Jan G. M. Klijn
    Cancer Res February 2 2001 61 (4) 1421-1425;

Endocrinology

  • Endocrinology
    Increased in Vivo Phosphorylation of Ret Tyrosine 1062 Is a Potential Pathogenetic Mechanism of Multiple Endocrine Neoplasia Type 2B
    Domenico Salvatore, Rosa Marina Melillo, Carmen Monaco, Roberta Visconti, Gianfranco Fenzi, Giancarlo Vecchio, Alfredo Fusco and Massimo Santoro
    Cancer Res February 2 2001 61 (4) 1426-1431;

  • Endocrinology
    Role of the Central Melanocortin System in Cachexia
    Daniel L. Marks, Nicholas Ling and Roger D. Cone
    Cancer Res February 2 2001 61 (4) 1432-1438;

  • Endocrinology
    Vitamin D Is a Prooxidant in Breast Cancer Cells
    Ruth Koren, Irit Hadari-Naor, Efrat Zuck, Carmela Rotem, Uri A. Liberman and Amiram Ravid
    Cancer Res February 2 2001 61 (4) 1439-1444;

Epidemiology and Prevention

  • Epidemiology and Prevention
    Sensitivity to DNA Damage Induced by Benzo(a)pyrene Diol Epoxide and Risk of Lung Cancer: A Case-Control Analysis
    Donghui Li, Pervez F. Firozi, Li-E Wang, Carol H. Bosken, Margaret R. Spitz, Waun Ki Hong and Qingyi Wei
    Cancer Res February 2 2001 61 (4) 1445-1450;

  • Epidemiology and Prevention
    Increased Expression of Cyclooxygenase-2 Protein in 4-Nitroquinoline-1-oxide-induced Rat Tongue Carcinomas and Chemopreventive Efficacy of a Specific Inhibitor, Nimesulide
    Hiroshi Shiotani, Ayumi Denda, Kazuhiko Yamamoto, Wakashi Kitayama, Takehiro Endoh, Yasutaka Sasaki, Masahiro Tsutsumi, Masahito Sugimura and Yoichi Konishi
    Cancer Res February 2 2001 61 (4) 1451-1456;

  • Epidemiology and Prevention
    Randomized Trial of Supplemental β-Carotene to Prevent Second Head and Neck Cancer
    Susan T. Mayne, Brenda Cartmel, Marianna Baum, Gail Shor-Posner, Barbara G. Fallon, Kenneth Briskin, Judy Bean, Tongzhang Zheng, Dennis Cooper, Craig Friedman and W. Jarrard Goodwin Jr.
    Cancer Res February 2 2001 61 (4) 1457-1463;

Experimental Therapeutics

  • Experimental Therapeutics
    Tyrosine Kinase Inhibition of Multiple Angiogenic Growth Factor Receptors Improves Survival in Mice Bearing Colon Cancer Liver Metastases by Inhibition of Endothelial Cell Survival Mechanisms
    Raymond M. Shaheen, William W. Tseng, Darren W. Davis, Wenbiao Liu, Niels Reinmuth, Roberto Vellagas, Andrew A. Wieczorek, Yasuhiro Ogura, David J. McConkey, Kenneth E. Drazan, Corazon D. Bucana, Gerald McMahon and Lee M. Ellis
    Cancer Res February 2 2001 61 (4) 1464-1468;

  • Experimental Therapeutics
    The Pharmacological Phenotype of Combined Multidrug-Resistance mdr1a/1b- and mrp1-deficient Mice
    Dennis R. Johnson, Rick A. Finch, Z. Ping Lin, Caroline J. Zeiss and Alan C. Sartorelli
    Cancer Res February 2 2001 61 (4) 1469-1476;

  • Experimental Therapeutics
    Combination of Phenylbutyrate and 13-cis Retinoic Acid Inhibits Prostate Tumor Growth and Angiogenesis
    Roberto Pili, Mark P. Kruszewski, Brant W. Hager, Julie Lantz and Michael A. Carducci
    Cancer Res February 2 2001 61 (4) 1477-1485;

  • Experimental Therapeutics
    Identification and Characterization of A-105972, an Antineoplastic Agent
    Jinshyun R. Wu-Wong, Jeffery D. Alder, Lisa Alder, David J. Burns, Edward K-H. Han, Bruce Credo, Stephen K. Tahir, Brian D. Dayton, Patricia J. Ewing and William J. Chiou
    Cancer Res February 2 2001 61 (4) 1486-1492;

  • Experimental Therapeutics
    Pharmacological Inhibition of Fatty Acid Synthase Activity Produces Both Cytostatic and Cytotoxic Effects Modulated by p53
    Ji-Nong Li, Myriam Gorospe, Francis J. Chrest, Tirukalikundram S. Kumaravel, Michele K. Evans, Wan Fang Han and Ellen S. Pizer
    Cancer Res February 2 2001 61 (4) 1493-1499;

  • Experimental Therapeutics
    The Level of MHC Class I Expression on Murine Adenocarcinoma Can Change the Antitumor Effector Mechanism of Immunocytokine Therapy
    Michael Imboden, Kristopher R. Murphy, Alexander L. Rakhmilevich, Zane C. Neal, Rong Xiang, Ralph A. Reisfeld, Stephen D. Gillies and Paul M. Sondel
    Cancer Res February 2 2001 61 (4) 1500-1507;

  • Experimental Therapeutics
    p53 Modulates the Effect of Loss of DNA Mismatch Repair on the Sensitivity of Human Colon Cancer Cells to the Cytotoxic and Mutagenic Effects of Cisplatin
    Xinjian Lin, Krishnan Ramamurthi, Misako Mishima, Akira Kondo, Randolph D. Christen and Stephen B. Howell
    Cancer Res February 2 2001 61 (4) 1508-1516;

  • Experimental Therapeutics
    Interferon-inducible Protein 10 Induction and Inhibition of Angiogenesis in Vivo by the Antitumor Agent 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA)
    Zhihui Cao, Bruce C Baguley and Lai-Ming Ching
    Cancer Res February 2 2001 61 (4) 1517-1521;

  • Experimental Therapeutics
    Methotrexate Accumulates to Similar Levels in Animals Transplanted with Normal versus Drug-resistant Transgenic Marrow
    Lalitha R. Belur, Debra Boelk-Galvan, Miechaleen D. Diers, R. Scott McIvor and Cheryl L. Zimmerman
    Cancer Res February 2 2001 61 (4) 1522-1526;

  • Experimental Therapeutics
    Antitumor Activity of the Rapamycin Analog CCI-779 in Human Primitive Neuroectodermal Tumor/Medulloblastoma Models as Single Agent and in Combination Chemotherapy
    Birgit Geoerger, Karol Kerr, Cheng-Bi Tang, Kar-Ming Fung, Bruce Powell, Leslie N. Sutton, Peter C. Phillips and Anna J. Janss
    Cancer Res February 2 2001 61 (4) 1527-1532;

  • Experimental Therapeutics
    Inhibition of Extracellular Signal-regulated Kinase (ERK) Mediates Cell Cycle Phase Independent Apoptosis in Vinblastine-treated ML-1 Cells
    Terrance A. Stadheim, Helen Xiao and Alan Eastman
    Cancer Res February 2 2001 61 (4) 1533-1540;

  • Experimental Therapeutics
    Inhibition of Extracellular Signal-regulated Kinase 1/2 Phosphorylation and Induction of Apoptosis by Sulindac Metabolites
    Pamela L. Rice, Ryan J. Goldberg, Evan C. Ray, Linda J. Driggers and Dennis J. Ahnen
    Cancer Res February 2 2001 61 (4) 1541-1547;

  • Experimental Therapeutics
    Targeting a Genetically Engineered Elastin-like Polypeptide to Solid Tumors by Local Hyperthermia
    Dan E. Meyer, Garheng A. Kong, Mark W. Dewhirst, Michael R. Zalutsky and Ashutosh Chilkoti
    Cancer Res February 2 2001 61 (4) 1548-1554;

  • Experimental Therapeutics
    Antibodies Elicited by Naked DNA Vaccination against the Complementary-determining Region 3 Hypervariable Region of Immunoglobulin Heavy Chain Idiotypic Determinants of B-lymphoproliferative Disorders Specifically React with Patients’ Tumor Cells
    Monica Rinaldi, Francesco Ria, Paola Parrella, Emanuela Signori, Anna Serra, Silvia A. Ciafrè, Isabella Vespignani, Marzia Lazzari, Maria Giulia Farace, Giuseppe Saglio and Vito M. Fazio
    Cancer Res February 2 2001 61 (4) 1555-1562;

Molecular Biology and Genetics

  • Molecular Biology and Genetics
    Identification and Characterization of Prostein, a Novel Prostate-specific Protein
    Jiangchun Xu, Michael Kalos, John A. Stolk, Eden J. Zasloff, Xinqun Zhang, Raymond L. Houghton, Aristides Maltez Filho, Marcos Nolasco, Roberto Badaró and Steven G. Reed
    Cancer Res February 2 2001 61 (4) 1563-1568;

  • Molecular Biology and Genetics
    Gene Expression Patterns Associated with the Metastatic Phenotype in Rodent and Human Tumors
    Andrea Nestl, Oliver D. Von Stein, Kurt Zatloukal, Wolf-Gerolf Thies, Peter Herrlich, Martin Hofmann and Jonathan P. Sleeman
    Cancer Res February 2 2001 61 (4) 1569-1577;

  • Molecular Biology and Genetics
    Effect of Adenoviral Transduction of the Fragile Histidine Triad Gene into Esophageal Cancer Cells
    Hideshi Ishii, Kristoffel R. Dumon, Andrea Vecchione, Francesco Trapasso, Koshi Mimori, Hansjuerg Alder, Masaki Mori, Gabriella Sozzi, Raffaele Baffa, Kay Huebner and Carlo M. Croce
    Cancer Res February 2 2001 61 (4) 1578-1584;

  • Molecular Biology and Genetics
    End-joining Deficiency and Radiosensitization Induced by Gemcitabine
    John W. G. van Putten, Harry J. M. Groen, Kees Smid, Godefridus J. Peters and Harm H. Kampinga
    Cancer Res February 2 2001 61 (4) 1585-1591;

  • Molecular Biology and Genetics
    Transcriptional Activation of the Human HMG1 Gene in Cisplatin-resistant Human Cancer Cells
    Gunji Nagatani, Minoru Nomoto, Hiroshi Takano, Tomoko Ise, Ken Kato, Toshihiro Imamura, Hiroto Izumi, Kazumi Makishima and Kimitoshi Kohno
    Cancer Res February 2 2001 61 (4) 1592-1597;

  • Molecular Biology and Genetics
    A Possible Role of p73 on the Modulation of p53 Level through MDM2
    Xiao Qi Wang, Weg M. Ongkeko, Anita W. S. Lau, Ka Man Leung and Randy Y. C. Poon
    Cancer Res February 2 2001 61 (4) 1598-1603;

  • Molecular Biology and Genetics
    Resveratrol-induced Activation of p53 and Apoptosis Is Mediated by Extracellular- Signal-regulated Protein Kinases and p38 Kinase
    Qing-Bai She, Ann M. Bode, Wei-Ya Ma, Nan-Yue Chen and Zigang Dong
    Cancer Res February 2 2001 61 (4) 1604-1610;

  • Molecular Biology and Genetics
    Prostate Short-Chain Dehydrogenase Reductase 1 (PSDR1): A New Member of the Short-Chain Steroid Dehydrogenase/Reductase Family Highly Expressed in Normal and Neoplastic Prostate Epithelium
    Biaoyang Lin, James T. White, Camari Ferguson, Shunyou Wang, Robert Vessella, Roger Bumgarner, Lawrence D. True, Leroy Hood and Peter S. Nelson
    Cancer Res February 2 2001 61 (4) 1611-1618;

  • Molecular Biology and Genetics
    MSH6 and MSH3 Are Rarely Involved in Genetic Predisposition to Nonpolypotic Colon Cancer
    Jiaqi Huang, Shannon A. Kuismanen, Tao Liu, Robert B. Chadwick, Cheryl K. Johnson, Michael W. Stevens, Samuel K. Richards, Julie E. Meek, Xin Gao, Fred A. Wright, Jukka-Pekka Mecklin, Heikki J. Järvinen, Henrik Grönberg, Marie Luise Bisgaard, Annika Lindblom and Päivi Peltomäki
    Cancer Res February 2 2001 61 (4) 1619-1623;

  • Molecular Biology and Genetics
    Cancer-specific Genomic Instability in Bronchial Lavage: A Molecular Tool for Lung Cancer Detection
    Triantafillos Liloglou, Paul Maloney, George Xinarianos, Melanie Hulbert, Martin J. Walshaw, John R. Gosney, Lesley Turnbull and John K. Field
    Cancer Res February 2 2001 61 (4) 1624-1628;

  • Molecular Biology and Genetics
    Templated Nucleotide Addition and Immunoglobulin JH-Gene Utilization in t(11;14) Junctions: Implications for the Mechanism of Translocation and the Origin of Mantle Cell Lymphoma
    Natascha Welzel, Trang Le, Rodrig Marculescu, Gerlinde Mitterbauer, Andreas Chott, Christiane Pott, Michael Kneba, Ming-Qing Du, Rajko Kusec, Johannes Drach, Markus Raderer, Christine Mannhalter, Klaus Lechner, Bertrand Nadel and Ulrich Jaeger
    Cancer Res February 2 2001 61 (4) 1629-1636;

Tumor Biology

  • Tumor Biology
    Receptor Activator of Nuclear Factor κB Ligand (RANKL) Is a Key Molecule of Osteoclast Formation for Bone Metastasis in a Newly Developed Model of Human Neuroblastoma
    Toshimi Michigami, Miyuki Ihara-Watanabe, Miwa Yamazaki and Keiichi Ozono
    Cancer Res February 2 2001 61 (4) 1637-1644;

  • Tumor Biology
    Anticancer Agents Sensitize Tumor Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Caspase-8 Activation and Apoptosis
    Sandrine Lacour, Arlette Hammann, Anne Wotawa, Laurent Corcos, Eric Solary and Marie-Thérèse Dimanche-Boitrel
    Cancer Res February 2 2001 61 (4) 1645-1651;

  • Tumor Biology
    Identification of CGA as a Novel Estrogen Receptor-responsive Gene in Breast Cancer: An Outstanding Candidate Marker to Predict the Response to Endocrine Therapy
    Ivan Bièche, Béatrice Parfait, Vivianne Le Doussal, Martine Olivi, Marie-Christine Rio, Rosette Lidereau and Michel Vidaud
    Cancer Res February 2 2001 61 (4) 1652-1658;

  • Tumor Biology
    DNA Fragments in the Blood Plasma of Cancer Patients: Quantitations and Evidence for Their Origin from Apoptotic and Necrotic Cells
    Sabine Jahr, Hannes Hentze, Sabine Englisch, Dieter Hardt, Frank O. Fackelmayer, Rolf-Dieter Hesch and Rolf Knippers
    Cancer Res February 2 2001 61 (4) 1659-1665;

  • Tumor Biology
    Prognostic Significance of Polysialic Acid Expression in Resected Non-Small Cell Lung Cancer
    Fumihiro Tanaka, Yosuke Otake, Tatsuo Nakagawa, Yozo Kawano, Ryo Miyahara, Mio Li, Kazuhiro Yanagihara, Kenji Inui, Hiroki Oyanagi, Tomoko Yamada, Jun Nakayama, Ichiro Fujimoto, Kazuhiro Ikenaka and Hiromi Wada
    Cancer Res February 2 2001 61 (4) 1666-1670;

  • Tumor Biology
    Geldanamycin Abrogates ErbB2 Association with Proteasome-resistant β-Catenin in Melanoma Cells, Increases β-Catenin-E-Cadherin Association, and Decreases β-Catenin-sensitive Transcription
    Paolo Bonvini, Won G. An, Angelo Rosolen, Phongmai Nguyen, Jane Trepel, Antonio Garcia de Herreros, Mireia Dunach and Leonard M. Neckers
    Cancer Res February 2 2001 61 (4) 1671-1677;

  • Tumor Biology
    Identification of Genes Involved in Human Urothelial Cell-Matrix Interactions: Implications for the Progression Pathways of Malignant Urothelium
    Barbara A. Smith, Wendy J. Kennedy, Patricia Harnden, Peter J. Selby, Ludwik K. Trejdosiewicz and Jennifer Southgate
    Cancer Res February 2 2001 61 (4) 1678-1685;

  • Tumor Biology
    Catalytic Cleavage of the Androgen-regulated TMPRSS2 Protease Results in Its Secretion by Prostate and Prostate Cancer Epithelia
    Daniel E. H. Afar, Igor Vivanco, Rene S. Hubert, James Kuo, Emily Chen, Douglas C. Saffran, Arthur B. Raitano and Aya Jakobovits
    Cancer Res February 2 2001 61 (4) 1686-1692;

  • Tumor Biology
    Drug Resistance Induced by Ouabain via the Stimulation of MDR1 Gene Expression in Human Carcinomatous Pulmonary Cells
    Franck Brouillard, Danielle Tondelier, Aleksander Edelman and Maryvonne Baudouin-Legros
    Cancer Res February 2 2001 61 (4) 1693-1698;

  • Tumor Biology
    Overexpression of BCL-XL Underlies the Molecular Basis for Resistance to Staurosporine-induced Apoptosis in PC-3 Cells
    XiaoYing Li, Michela Marani, Roberta Mannucci, Berma Kinsey, Francesca Andriani, Ildo Nicoletti, Larry Denner and Marco Marcelli
    Cancer Res February 2 2001 61 (4) 1699-1706;

  • Tumor Biology
    Anoikis and Metastatic Potential of Cloudman S91 Melanoma Cells
    Zhenyu Zhu, Otto Sanchez-Sweatman, Xiaojun Huang, Robert Wiltrout, Rama Khokha, Qun Zhao and Elieser Gorelik
    Cancer Res February 2 2001 61 (4) 1707-1716;

  • Tumor Biology
    Inhibition of Fibroblast Growth Factor/Fibroblast Growth Factor Receptor Activity in Glioma Cells Impedes Tumor Growth by Both Angiogenesis-dependent and -independent Mechanisms
    Patrick Auguste, Demirkan B. Gürsel, Sylvie Lemière, Diana Reimers, Pedro Cuevas, Fernando Carceller, James P. Di Santo and Andreas Bikfalvi
    Cancer Res February 2 2001 61 (4) 1717-1726;

  • Tumor Biology
    Up-Regulation of Vascular Endothelial Growth Factor in Breast Cancer Cells by the Heregulin-β1-activated p38 Signaling Pathway Enhances Endothelial Cell Migration
    Shunbin Xiong, Rebecca Grijalva, Lianglin Zhang, Nina T. Nguyen, Peter W. Pisters, Raphael E. Pollock and Dihua Yu
    Cancer Res February 2 2001 61 (4) 1727-1732;

  • Tumor Biology
    Chemoprevention of Intestinal Polyposis in the ApcΔ716 Mouse by Rofecoxib, a Specific Cyclooxygenase-2 Inhibitor
    Masanobu Oshima, Naomi Murai(Hata), Stacia Kargman, Meztli Arguello, Pauline Luk, Elizabeth Kwong, Makoto M. Taketo and Jilly F. Evans
    Cancer Res February 2 2001 61 (4) 1733-1740;

  • Tumor Biology
    Mechanism of Functional Inactivation of a Li-Fraumeni Syndrome p53 That Has a Mutation Outside of the DNA-binding Domain
    Jijie Gu, Hidehiko Kawai, Dmitri Wiederschain and Zhi-Min Yuan
    Cancer Res February 2 2001 61 (4) 1741-1746;

  • Tumor Biology
    A Novel Serine-dependent Proteolytic Activity Is Responsible for Truncated Signal Transducer and Activator of Transcription Proteins in Acute Myeloid Leukemia Blasts
    Zheng Xia, Robert R. Salzler, Daniel P. Kunz, Maria R. Baer, Latif Kazim, Heinz Baumann and Meir Wetzler
    Cancer Res February 2 2001 61 (4) 1747-1753;

Virology

  • Virology
    Identification of a Proviral Structure in Human Breast Cancer
    Bingren Liu, Yue Wang, Stella M. Melana, Isabelle Pelisson, Vesna Najfeld, James F. Holland and Beatriz G-T. Pogo
    Cancer Res February 2 2001 61 (4) 1754-1759;

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Cancer Research: 61 (4)
February 2001
Volume 61, Issue 4
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  • Towards Multidrug Adaptive Therapy
  • MEK Inhibition Synergizes with Statins for Cancer Treatment
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  • Multiple Primary Cancer Penetrance for TP53
  • Metabolomic Gradients in Glioblastoma Models
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Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

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