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Cell and Tumor Biology

Adenoviral-Mediated Expression of a Kinase-Dead Mutant of Akt Induces Apoptosis Selectively in Tumor Cells and Suppresses Tumor Growth in Mice

Amanda Jetzt, John A. Howe, Mark T. Horn, Eugene Maxwell, Zhizhang Yin, Duane Johnson and C. Chandra Kumar
Amanda Jetzt
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John A. Howe
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Mark T. Horn
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Eugene Maxwell
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Zhizhang Yin
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Duane Johnson
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C. Chandra Kumar
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DOI:  Published October 2003
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Article Information

Volume 63, Issue 20, pp. 6697-6706

PubMed 
14583464

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received March 18, 2003
  • Revision received June 30, 2003
  • Accepted July 25, 2003
  • Published first October 28, 2003.

Copyright & Usage 
©2003 American Association for Cancer Research.

Author Information

  1. Amanda Jetzt,
  2. John A. Howe,
  3. Mark T. Horn,
  4. Eugene Maxwell,
  5. Zhizhang Yin,
  6. Duane Johnson, and
  7. C. Chandra Kumar1
  1. Department of Tumor Biology, Schering-Plough Research Institute, Kenilworth, New Jersey 07033 [A. J., E. M., Z. H., C. C. K.], and Canji, Inc., La Jolla, California 92121 [J. A. H., M. T. H., D. J.]
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Cancer Research: 63 (20)
October 2003
Volume 63, Issue 20
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Adenoviral-Mediated Expression of a Kinase-Dead Mutant of Akt Induces Apoptosis Selectively in Tumor Cells and Suppresses Tumor Growth in Mice
Amanda Jetzt, John A. Howe, Mark T. Horn, Eugene Maxwell, Zhizhang Yin, Duane Johnson and C. Chandra Kumar
Cancer Res October 15 2003 (63) (20) 6697-6706;

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Adenoviral-Mediated Expression of a Kinase-Dead Mutant of Akt Induces Apoptosis Selectively in Tumor Cells and Suppresses Tumor Growth in Mice
Amanda Jetzt, John A. Howe, Mark T. Horn, Eugene Maxwell, Zhizhang Yin, Duane Johnson and C. Chandra Kumar
Cancer Res October 15 2003 (63) (20) 6697-6706;
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  • Development of Ewing's Sarcoma from Primary Bone Marrow–Derived Mesenchymal Progenitor Cells
  • Gold(III) Porphyrin 1a Induced Apoptosis by Mitochondrial Death Pathways Related to Reactive Oxygen Species
  • Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction
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Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

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