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Cancer Research
Cancer Research
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About the Cover

Cover image

Cover image expansion

Model of docked structure of theaflavin-3' gallate (ball and sticks) into the BH3 binding pocket of Bcl-xL (surface representation). The docked structure and surface representation were generated with Sybyl-FlexX and MOLCAD, respectively. The surface was color coded according to cavity dept (blue, shallow; yellow, buried). The compound inhibits the binding of Bcl-xL to a BH3 peptide in the nanomolar range. For details, see the article by Leone et al. on p. 8118 of this issue.

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Cancer Research: 63 (23)
December 2003
Volume 63, Issue 23
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Issue Highlights

  • Cancer Prevention by Tea Polyphenols Is Linked to Their Direct Inhibition of Antiapoptotic Bcl-2-Family Proteins
  • Short Telomeres and Ataxia-Telangiectasia Mutated Deficiency Cooperatively Increase Telomere Dysfunction and Suppress Tumorigenesis
  • A Multimodal Nanoparticle for Preoperative Magnetic Resonance Imaging and Intraoperative Optical Brain Tumor Delineation
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Copyright © 2021 by the American Association for Cancer Research.

Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

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