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Table of Contents

Advances in Brief

  • Advances in Brief
    Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-2 Fusion cDNA for Cancer Gene Immunotherapy
    John Stagg, Jian Hui Wu, Nathaniel Bouganim and Jacques Galipeau
    Cancer Res December 15 2004 64 (24) 8795-8799; DOI:10.1158/0008-5472.CAN-04-1776

  • Advances in Brief
    NIMA-Related Protein Kinase 1 Is Involved Early in the Ionizing Radiation-Induced DNA Damage Response
    Rosaria Polci, Aimin Peng, Phang-Lang Chen, Daniel J. Riley and Yumay Chen
    Cancer Res December 15 2004 64 (24) 8800-8803; DOI:10.1158/0008-5472.CAN-04-2243

  • Advances in Brief
    Conditional Expression of K-ras in an Epithelial Compartment that Includes the Stem Cells Is Sufficient to Promote Squamous Cell Carcinogenesis
    Lynn Vitale-Cross, Panomwat Amornphimoltham, Galen Fisher, Alfredo A. Molinolo and J. Silvio Gutkind
    Cancer Res December 15 2004 64 (24) 8804-8807; DOI:10.1158/0008-5472.CAN-04-2623

  • Advances in Brief
    Crucial Role of Phospholipase Cε in Chemical Carcinogen-Induced Skin Tumor Development
    Yunfeng Bai, Hironori Edamatsu, Sakan Maeda, Hiromitsu Saito, Noboru Suzuki, Takaya Satoh and Tohru Kataoka
    Cancer Res December 15 2004 64 (24) 8808-8810; DOI:10.1158/0008-5472.CAN-04-3143

  • Advances in Brief
    Down-Regulation of Regulatory Subunit Type 1A of Protein Kinase A Leads to Endocrine and Other Tumors
    Kurt J. Griffin, Lawrence S. Kirschner, Ludmila Matyakhina, Sotirios Stergiopoulos, Audrey Robinson-White, Sara Lenherr, Frank D. Weinberg, Edward Claflin, Elise Meoli, Yoon S. Cho-Chung and Constantine A. Stratakis
    Cancer Res December 15 2004 64 (24) 8811-8815; DOI:10.1158/0008-5472.CAN-04-3620

  • Advances in Brief
    Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia
    Mohamed Bentires-Alj, J. Guillermo Paez, Frank S. David, Heike Keilhack, Balazs Halmos, Katsuhiko Naoki, John M. Maris, Andrea Richardson, Alberto Bardelli, David J. Sugarbaker, William G. Richards, Jinyan Du, Luc Girard, John D. Minna, Mignon L. Loh, David E. Fisher, Victor E. Velculescu, Bert Vogelstein, Matthew Meyerson, William R. Sellers and Benjamin G. Neel
    Cancer Res December 15 2004 64 (24) 8816-8820; DOI:10.1158/0008-5472.CAN-04-1923

  • Advances in Brief
    Recombinant Listeria Vaccines Containing PEST Sequences Are Potent Immune Adjuvants for the Tumor-Associated Antigen Human Papillomavirus-16 E7
    Duane A. Sewell, Vafa Shahabi, George R. Gunn III, Zhen-Kun Pan, Mary E. Dominiecki and Yvonne Paterson
    Cancer Res December 15 2004 64 (24) 8821-8825; DOI:10.1158/0008-5472.CAN-04-1958

  • Advances in Brief
    2-Arachidonoylglycerol
    Kasem Nithipatikom, Michael P. Endsley, Marilyn A. Isbell, John R. Falck, Yoshiki Iwamoto, Cecilia J. Hillard and William B. Campbell
    Cancer Res December 15 2004 64 (24) 8826-8830; DOI:10.1158/0008-5472.CAN-04-3136

Molecular Biology, Pathobiology and Genetics

  • Molecular Biology, Pathobiology and Genetics
    Cysteine Cathepsins Are Central Contributors of Invasion by Cultured Adenosylmethionine Decarboxylase-Transformed Rodent Fibroblasts
    Kirsi Ravanko, Kristiina Järvinen, Jari Helin, Nisse Kalkkinen and Erkki Hölttä
    Cancer Res December 15 2004 64 (24) 8831-8838; DOI:10.1158/0008-5472.CAN-03-2993

  • Molecular Biology, Pathobiology and Genetics
    Evidence for the Involvement of Double-Strand Breaks in Heat-Induced Cell Killing
    Akihisa Takahashi, Hideki Matsumoto, Kosuke Nagayama, Mutsuko Kitano, Sayako Hirose, Hidenori Tanaka, Eiichiro Mori, Nobuhiro Yamakawa, Jun-ichi Yasumoto, Kazue Yuki, Ken Ohnishi and Takeo Ohnishi
    Cancer Res December 15 2004 64 (24) 8839-8845; DOI:10.1158/0008-5472.CAN-04-1876

  • Molecular Biology, Pathobiology and Genetics
    A Differential Gene Expression Profile Reveals Overexpression of RUNX1/AML1 in Invasive Endometrioid Carcinoma
    Jesús Planagumà, María Díaz-Fuertes, Antonio Gil-Moreno, Miguel Abal, Marta Monge, Angel García, Teresa Baró, Timothy M. Thomson, Jordi Xercavins, Francesc Alameda and Jaume Reventós
    Cancer Res December 15 2004 64 (24) 8846-8853; DOI:10.1158/0008-5472.CAN-04-2066

  • Molecular Biology, Pathobiology and Genetics
    Polycyclic Aromatic Hydrocarbon-DNA Adducts in Prostate Cancer
    Benjamin A. Rybicki, Andrew Rundle, Adnan T. Savera, Steadman S. Sankey and Deliang Tang
    Cancer Res December 15 2004 64 (24) 8854-8859; DOI:10.1158/0008-5472.CAN-04-2323

  • Molecular Biology, Pathobiology and Genetics
    Wnt3a Growth Factor Induces Androgen Receptor-Mediated Transcription and Enhances Cell Growth in Human Prostate Cancer Cells
    Meletios Verras, Jeffrey Brown, Xiaomeng Li, Roel Nusse and Zijie Sun
    Cancer Res December 15 2004 64 (24) 8860-8866; DOI:10.1158/0008-5472.CAN-04-2370

  • Molecular Biology, Pathobiology and Genetics
    Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells
    Raanan Berger, Phillip G. Febbo, Pradip K. Majumder, Jean J. Zhao, Shayan Mukherjee, Sabina Signoretti, K. Thirza Campbell, William R. Sellers, Thomas M. Roberts, Massimo Loda, Todd R. Golub and William C. Hahn
    Cancer Res December 15 2004 64 (24) 8867-8875; DOI:10.1158/0008-5472.CAN-04-2938

  • Molecular Biology, Pathobiology and Genetics
    Myh Deficiency Enhances Intestinal Tumorigenesis in Multiple Intestinal Neoplasia (ApcMin/+) Mice
    Oliver M. Sieber, Kimberley M. Howarth, Christina Thirlwell, Andrew Rowan, Nikki Mandir, Robert A. Goodlad, Ashfaq Gilkar, Bradley Spencer-Dene, Gordon Stamp, Victoria Johnson, Andrew Silver, Hanjing Yang, Jeffrey H. Miller, Mohammad Ilyas and Ian P. M. Tomlinson
    Cancer Res December 15 2004 64 (24) 8876-8881; DOI:10.1158/0008-5472.CAN-04-2958

  • Molecular Biology, Pathobiology and Genetics
    Involvement of Illegitimate V(D)J Recombination or Microhomology-Mediated Nonhomologous End-Joining in the Formation of Intragenic Deletions of the Notch1 Gene in Mouse Thymic Lymphomas
    Hideo Tsuji, Hiroko Ishii-Ohba, Takanori Katsube, Hideki Ukai, Shiro Aizawa, Masahiro Doi, Kyoji Hioki and Toshiaki Ogiu
    Cancer Res December 15 2004 64 (24) 8882-8890; DOI:10.1158/0008-5472.CAN-03-1163

  • Molecular Biology, Pathobiology and Genetics
    Estrogen Receptor Genotypes and Haplotypes Associated with Breast Cancer Risk
    Bert Gold, Francis Kalush, Julie Bergeron, Kevin Scott, Nandita Mitra, Kelly Wilson, Nathan Ellis, Helen Huang, Michael Chen, Ross Lippert, Bjarni V. Halldorsson, Beth Woodworth, Thomas White, Andrew G. Clark, Fritz F. Parl, Samuel Broder, Michael Dean and Kenneth Offit
    Cancer Res December 15 2004 64 (24) 8891-8900; DOI:10.1158/0008-5472.CAN-04-1256

  • Molecular Biology, Pathobiology and Genetics
    Enhancer-Dependent Splicing of FGFR1 α-Exon Is Repressed by RNA Interference-Mediated Down-Regulation of SRp55
    Wei Jin and Gilbert J. Cote
    Cancer Res December 15 2004 64 (24) 8901-8905; DOI:10.1158/0008-5472.CAN-04-0716

  • Molecular Biology, Pathobiology and Genetics
    Large-Scale Association Study Identifies ICAM Gene Region as Breast and Prostate Cancer Susceptibility Locus
    Stefan Kammerer, Richard B. Roth, Richard Reneland, George Marnellos, Carolyn R. Hoyal, Nathan J. Markward, Florian Ebner, Marion Kiechle, Ulrike Schwarz-Boeger, Lyn R. Griffiths, Christian Ulbrich, Korbinian Chrobok, Gerhard Forster, Georg M. Praetorius, Peter Meyer, Joachim Rehbock, Charles R. Cantor, Matthew R. Nelson and Andreas Braun
    Cancer Res December 15 2004 64 (24) 8906-8910; DOI:10.1158/0008-5472.CAN-04-1788

  • Molecular Biology, Pathobiology and Genetics
    A Novel RARβ Isoform Directed by a Distinct Promoter P3 and Mediated by Retinoic Acid in Breast Cancer Cells
    Xinjian Peng, Takeshi Maruo, Yanxia Cao, Vasu Punj, Rajeshwari Mehta, Tapas K. Das Gupta and Konstantin Christov
    Cancer Res December 15 2004 64 (24) 8911-8918; DOI:10.1158/0008-5472.CAN-04-1810

  • Molecular Biology, Pathobiology and Genetics
    Mutations of the Epidermal Growth Factor Receptor Gene in Lung Cancer
    Takayuki Kosaka, Yasushi Yatabe, Hideki Endoh, Hiroyuki Kuwano, Takashi Takahashi and Tetsuya Mitsudomi
    Cancer Res December 15 2004 64 (24) 8919-8923; DOI:10.1158/0008-5472.CAN-04-2818

Cell and Tumor Biology

  • Cell and Tumor Biology
    Microtubule-Dependent Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Exocytosis
    Eva-Maria Schnaeker, Rainer Ossig, Thomas Ludwig, Rita Dreier, Hans Oberleithner, M. Wilhelmi and Stefan W. Schneider
    Cancer Res December 15 2004 64 (24) 8924-8931; DOI:10.1158/0008-5472.CAN-04-0324

  • Cell and Tumor Biology
    Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in Angiogenesis and Invasion of Human Urinary Bladder Cancer
    Leticia Oliveira-Ferrer, Derya Tilki, Gudrun Ziegeler, Jessica Hauschild, Sonja Loges, Ster Irmak, Ergin Kilic, Hartwig Huland, Martin Friedrich and Süleyman Ergün
    Cancer Res December 15 2004 64 (24) 8932-8938; DOI:10.1158/0008-5472.CAN-04-0505

  • Cell and Tumor Biology
    Protein Kinase D2 Mediates Activation of Nuclear Factor κB by Bcr-Abl in Bcr-Abl+ Human Myeloid Leukemia Cells
    Tamara Mihailovic, Martin Marx, Alexandra Auer, Johan Van Lint, Mathias Schmid, Christoph Weber and Thomas Seufferlein
    Cancer Res December 15 2004 64 (24) 8939-8944; DOI:10.1158/0008-5472.CAN-04-0981

  • Cell and Tumor Biology
    Endothelin Receptor B Inhibition Triggers Apoptosis and Enhances Angiogenesis in Melanomas
    Ronit Lahav, Mario-Luca Suvà, Donata Rimoldi, Paul H. Patterson and Ivan Stamenkovic
    Cancer Res December 15 2004 64 (24) 8945-8953; DOI:10.1158/0008-5472.CAN-04-1510

  • Cell and Tumor Biology
    A Major Role for Mitotic cdc2 Kinase Inactivation in the Establishment of the Mitotic DNA Damage Checkpoint
    Emilie Bayart, Olga Grigorieva, Serge Leibovitch, Rosine Onclercq-Delic and Mounira Amor-Guéret
    Cancer Res December 15 2004 64 (24) 8954-8959; DOI:10.1158/0008-5472.CAN-04-1613

  • Cell and Tumor Biology
    Caspase-Independent Cell Death by Arsenic Trioxide in Human Cervical Cancer Cells
    Young-Hee Kang, Min-Jung Yi, Min-Jung Kim, Moon-Taek Park, Sangwoo Bae, Chang-Mo Kang, Chul-Koo Cho, In-Chul Park, Myung-Jin Park, Chang Hun Rhee, Seok-Il Hong, Hee Yong Chung, Yun-Sil Lee and Su-Jae Lee
    Cancer Res December 15 2004 64 (24) 8960-8967; DOI:10.1158/0008-5472.CAN-04-1830

  • Cell and Tumor Biology
    Soluble Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Overexpression in HEK293 Cells Promotes Tumor Growth and Angiogenesis in Athymic Nude Mice
    David H. Ho, Hong Vu, Sharron A. N. Brown, Patrick J. Donohue, Heather N. Hanscom and Jeffrey A. Winkles
    Cancer Res December 15 2004 64 (24) 8968-8972; DOI:10.1158/0008-5472.CAN-04-1879

  • Cell and Tumor Biology
    Role of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand in Interferon-Induced Apoptosis in Human Bladder Cancer Cells
    Angela Papageorgiou, Laura Lashinger, Randall Millikan, H. Barton Grossman, William Benedict, Colin P. N. Dinney and David J. McConkey
    Cancer Res December 15 2004 64 (24) 8973-8979; DOI:10.1158/0008-5472.CAN-04-1909

  • Cell and Tumor Biology
    Cyclin G2 Dysregulation in Human Oral Cancer
    Yong Kim, Satoru Shintani, Yohko Kohno, Rong Zhang and David T. Wong
    Cancer Res December 15 2004 64 (24) 8980-8986; DOI:10.1158/0008-5472.CAN-04-1926

  • Cell and Tumor Biology
    Microarray-based Detection of Multidrug Resistance in Human Tumor Cells by Expression Profiling of ATP-binding Cassette Transporter Genes
    Jean-Pierre Gillet, Thomas Efferth, Daniel Steinbach, Jacques Hamels, Françoise de Longueville, Vincent Bertholet and José Remacle
    Cancer Res December 15 2004 64 (24) 8987-8993; DOI:10.1158/0008-5472.CAN-04-1978

  • Cell and Tumor Biology
    Conditional ROCK Activation In vivo Induces Tumor Cell Dissemination and Angiogenesis
    Daniel R. Croft, Erik Sahai, Georgia Mavria, Shuixing Li, Jeff Tsai, William M. F. Lee, Christopher J. Marshall and Michael F. Olson
    Cancer Res December 15 2004 64 (24) 8994-9001; DOI:10.1158/0008-5472.CAN-04-2052

  • Cell and Tumor Biology
    Conditional Overexpression of Active Transforming Growth Factor β1 In vivo Accelerates Metastases of Transgenic Mammary Tumors
    Rebecca S. Muraoka-Cook, Hirokazu Kurokawa, Yasuhiro Koh, James T. Forbes, L. Renee Roebuck, Mary Helen Barcellos-Hoff, Susan E. Moody, Lewis A. Chodosh and Carlos L. Arteaga
    Cancer Res December 15 2004 64 (24) 9002-9011; DOI:10.1158/0008-5472.CAN-04-2111

  • Cell and Tumor Biology
    The Minimal Active Domain of Endostatin Is a Heparin-Binding Motif that Mediates Inhibition of Tumor Vascularization
    Anna-Karin Olsson, Irja Johansson, Helena Åkerud, Barbro Einarsson, Rolf Christofferson, Takako Sasaki, Rupert Timpl and Lena Claesson-Welsh
    Cancer Res December 15 2004 64 (24) 9012-9017; DOI:10.1158/0008-5472.CAN-04-2172

  • Cell and Tumor Biology
    Protein Expression Profiles in Pancreatic Adenocarcinoma Compared with Normal Pancreatic Tissue and Tissue Affected by Pancreatitis as Detected by Two-Dimensional Gel Electrophoresis and Mass Spectrometry
    Jianjun Shen, Maria D. Person, Jijiang Zhu, James L. Abbruzzese and Donghui Li
    Cancer Res December 15 2004 64 (24) 9018-9026; DOI:10.1158/0008-5472.CAN-04-3262

  • Cell and Tumor Biology
    Immortalization of Human Bronchial Epithelial Cells in the Absence of Viral Oncoproteins
    Ruben D. Ramirez, Shelley Sheridan, Luc Girard, Mitsuo Sato, Young Kim, Jon Pollack, Michael Peyton, Ying Zou, Jonathan M. Kurie, J. Michael DiMaio, Sara Milchgrub, Alice L. Smith, Rhonda F. Souza, Laura Gilbey, Xi Zhang, Kenia Gandia, Melville B. Vaughan, Woodring E. Wright, Adi F. Gazdar, Jerry W. Shay and John D. Minna
    Cancer Res December 15 2004 64 (24) 9027-9034; DOI:10.1158/0008-5472.CAN-04-3703

  • Cell and Tumor Biology
    Inhibition of Chk1 by CEP-3891 Accelerates Mitotic Nuclear Fragmentation in Response to Ionizing Radiation
    Randi G. Syljuåsen, Claus Storgaard Sørensen, Jesper Nylandsted, Claudia Lukas, Jiri Lukas and Jiri Bartek
    Cancer Res December 15 2004 64 (24) 9035-9040; DOI:10.1158/0008-5472.CAN-04-2434

  • Cell and Tumor Biology
    Functional Integrity of Nuclear Factor κB, Phosphatidylinositol 3′-Kinase, and Mitogen-Activated Protein Kinase Signaling Allows Tumor Necrosis Factor α-Evoked Bcl-2 Expression to Provoke Internal Ribosome Entry Site-Dependent Translation of Hypoxia-Inducible Factor 1α
    Jie Zhou, Melvin Callapina, Gregory J. Goodall and Bernhard Brüne
    Cancer Res December 15 2004 64 (24) 9041-9048; DOI:10.1158/0008-5472.CAN-04-1437

  • Cell and Tumor Biology
    Differentiation of Human Prostate Cancer PC-3 Cells Induced by Inhibitors of Inosine 5′-Monophosphate Dehydrogenase
    Daniel Floryk, Sandra L. Tollaksen, Carol S. Giometti and Eliezer Huberman
    Cancer Res December 15 2004 64 (24) 9049-9056; DOI:10.1158/0008-5472.CAN-04-1553

  • Cell and Tumor Biology
    c-Jun NH2-Terminal Kinase Activation Contributes to Hypoxia-Inducible Factor 1α–Dependent P-Glycoprotein Expression in Hypoxia
    Katrina M. Comerford, Eoin P. Cummins and Cormac T. Taylor
    Cancer Res December 15 2004 64 (24) 9057-9061; DOI:10.1158/0008-5472.CAN-04-1919

  • Cell and Tumor Biology
    Tissue Inhibitors of Metalloproteinase 2 Inhibits Endothelial Cell Migration through Increased Expression of RECK
    Junseo Oh, Dong-Wan Seo, Tere Diaz, Beiyang Wei, Yvona Ward, Jill M. Ray, Yoko Morioka, Shuliang Shi, Hitoshi Kitayama, Chiaki Takahashi, Makoto Noda and William G. Stetler-Stevenson
    Cancer Res December 15 2004 64 (24) 9062-9069; DOI:10.1158/0008-5472.CAN-04-1981

  • Cell and Tumor Biology
    Insulin Regulates Cleavage of Procaspase-9 via Binding of X Chromosome-Linked Inhibitor of Apoptosis Protein in HT-29 Cells
    Ji-Eun Kim and Steven R. Tannenbaum
    Cancer Res December 15 2004 64 (24) 9070-9075; DOI:10.1158/0008-5472.CAN-04-2344

  • Cell and Tumor Biology
    Mitogen- and Stress-Activated Protein Kinase 1 Activity and Histone H3 Phosphorylation in Oncogene-Transformed Mouse Fibroblasts
    Bojan Drobic, Paula S. Espino and James R. Davie
    Cancer Res December 15 2004 64 (24) 9076-9079; DOI:10.1158/0008-5472.CAN-04-2369

  • Cell and Tumor Biology
    Adenoviral E1A Targets Mdm4 to Stabilize Tumor Suppressor p53
    Zheng Li, Chi-Ping Day, Jer-Yen Yang, Wen-Bin Tsai, Guillermina Lozano, Hsiu-Ming Shih and Mien-Chie Hung
    Cancer Res December 15 2004 64 (24) 9080-9085; DOI:10.1158/0008-5472.CAN-04-2419

Experimental Therapeutics, Molecular Targets, and Chemical Biology

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Tetrandrine Induces Early G1 Arrest in Human Colon Carcinoma Cells by Down-Regulating the Activity and Inducing the Degradation of G1-S–Specific Cyclin-Dependent Kinases and by Inducing p53 and p21Cip1
    Ling-hua Meng, Hongliang Zhang, Larry Hayward, Haruyuki Takemura, Rong-Guang Shao and Yves Pommier
    Cancer Res December 15 2004 64 (24) 9086-9092; DOI:10.1158/0008-5472.CAN-04-0313

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Early Changes in Protein Expression Detected by Mass Spectrometry Predict Tumor Response to Molecular Therapeutics
    Michelle L. Reyzer, Robert L. Caldwell, Teresa C. Dugger, James T. Forbes, Christoph A. Ritter, Marta Guix, Carlos L. Arteaga and Richard M. Caprioli
    Cancer Res December 15 2004 64 (24) 9093-9100; DOI:10.1158/0008-5472.CAN-04-2231

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Small In-Frame Deletion in the Epidermal Growth Factor Receptor as a Target for ZD6474
    Tokuzo Arao, Hisao Fukumoto, Masayuki Takeda, Tomohide Tamura, Nagahiro Saijo and Kazuto Nishio
    Cancer Res December 15 2004 64 (24) 9101-9104; DOI:10.1158/0008-5472.CAN-04-2360

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL
    Rajani Ravi, Ajay J. Jain, Richard D. Schulick, Vui Pham, Traci S. Prouser, Heather Allen, Elizabeth Garrett Mayer, Hua Yu, Drew M. Pardoll, Avi Ashkenazi and Atul Bedi
    Cancer Res December 15 2004 64 (24) 9105-9114; DOI:10.1158/0008-5472.CAN-04-2488

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Agents with Selective Estrogen Receptor (ER) Modulator Activity Induce Apoptosis In vitro and In vivo in ER-Negative Glioma Cells
    Ai-Min Hui, Wei Zhang, Wei Chen, Dan Xi, Benjamin Purow, Glenn C. Friedman and Howard A. Fine
    Cancer Res December 15 2004 64 (24) 9115-9123; DOI:10.1158/0008-5472.CAN-04-2740

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Prolonged Culture of Vaccine-Primed Lymphocytes Results in Decreased Antitumor Killing and Change in Cytokine Secretion
    Jeffrey J. Sussman, Robin Parihar, Karen Winstead and Fred D. Finkelman
    Cancer Res December 15 2004 64 (24) 9124-9130; DOI:10.1158/0008-5472.CAN-03-0376

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    The Human Glutathione S-Transferase P1 Protein Is Phosphorylated and Its Metabolic Function Enhanced by the Ser/Thr Protein Kinases, cAMP-Dependent Protein Kinase and Protein Kinase C, in Glioblastoma Cells
    Hui-Wen Lo, Gamil R. Antoun and Francis Ali-Osman
    Cancer Res December 15 2004 64 (24) 9131-9138; DOI:10.1158/0008-5472.CAN-04-0283

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    An Epidermal Growth Factor Receptor Intron 1 Polymorphism Mediates Response to Epidermal Growth Factor Receptor Inhibitors
    Maria L. Amador, Darin Oppenheimer, Sofia Perea, Anirban Maitra, George Cusati, Christi Iacobuzio-Donahue, Sharyn D. Baker, Raheela Ashfaq, Chris Takimoto, Arlene Forastiere and Manuel Hidalgo
    Cancer Res December 15 2004 64 (24) 9139-9143; DOI:10.1158/0008-5472.CAN-04-1036

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    HPC1/RNASEL Mediates Apoptosis of Prostate Cancer Cells Treated with 2′,5′-Oligoadenylates, Topoisomerase I Inhibitors, and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand
    Krishnamurthy Malathi, Jayashree M. Paranjape, Ram Ganapathi and Robert H. Silverman
    Cancer Res December 15 2004 64 (24) 9144-9151; DOI:10.1158/0008-5472.CAN-04-2226

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
    Ian Hickson, Yan Zhao, Caroline J. Richardson, Sharon J. Green, Niall M. B. Martin, Alisdair I. Orr, Philip M. Reaper, Stephen P. Jackson, Nicola J. Curtin and Graeme C. M. Smith
    Cancer Res December 15 2004 64 (24) 9152-9159; DOI:10.1158/0008-5472.CAN-04-2727

Immunology

  • Immunology
    Specific Recognition and Killing of Glioblastoma Multiforme by Interleukin 13-Zetakine Redirected Cytolytic T Cells
    Kanwarpal S. Kahlon, Christine Brown, Laurence J. N. Cooper, Andrew Raubitschek, Stephen J. Forman and Michael C. Jensen
    Cancer Res December 15 2004 64 (24) 9160-9166; DOI:10.1158/0008-5472.CAN-04-0454

  • Immunology
    Intratumor Heterogeneity of Cancer/Testis Antigens Expression in Human Cutaneous Melanoma Is Methylation-Regulated and Functionally Reverted by 5-Aza-2′-deoxycytidine
    Luca Sigalotti, Elisabetta Fratta, Sandra Coral, Silvia Tanzarella, Riccardo Danielli, Francesca Colizzi, Ester Fonsatti, Catia Traversari, Maresa Altomonte and Michele Maio
    Cancer Res December 15 2004 64 (24) 9167-9171; DOI:10.1158/0008-5472.CAN-04-1442

  • Immunology
    Vδ1 T Lymphocytes from B-CLL Patients Recognize ULBP3 Expressed on Leukemic B Cells and Up-Regulated by Trans-Retinoic Acid
    Alessandro Poggi, Claudia Venturino, Silvia Catellani, Marino Clavio, Maurizio Miglino, Marco Gobbi, Alexander Steinle, Paolo Ghia, Stefania Stella, Federico Caligaris-Cappio and Maria Raffaella Zocchi
    Cancer Res December 15 2004 64 (24) 9172-9179; DOI:10.1158/0008-5472.CAN-04-2417

  • Immunology
    Natural Killer Cell-Mediated Killing of Freshly Isolated Neuroblastoma Cells
    Roberta Castriconi, Alessandra Dondero, Maria Valeria Corrias, Edoardo Lanino, Daniela Pende, Lorenzo Moretta, Cristina Bottino and Alessandro Moretta
    Cancer Res December 15 2004 64 (24) 9180-9184; DOI:10.1158/0008-5472.CAN-04-2682

Endocrinology

  • Endocrinology
    HOXB13 Induces Growth Suppression of Prostate Cancer Cells as a Repressor of Hormone-Activated Androgen Receptor Signaling
    Chaeyong Jung, Ran-Sook Kim, Hong-Ji Zhang, Sang-Jin Lee and Meei-Huey Jeng
    Cancer Res December 15 2004 64 (24) 9185-9192; DOI:10.1158/0008-5472.CAN-04-1330

  • Endocrinology
    Proliferation of Transformed Somatotroph Cells Related to Low or Absent Expression of Protein Kinase A Regulatory Subunit 1A Protein
    Andrea G. Lania, Giovanna Mantovani, Stefano Ferrero, Caterina Pellegrini, Sara Bondioni, Erika Peverelli, Paola Braidotti, Marco Locatelli, Mario L. Zavanone, Emanuela Ferrante, Silvano Bosari, Paolo Beck-Peccoz and Anna Spada
    Cancer Res December 15 2004 64 (24) 9193-9198; DOI:10.1158/0008-5472.CAN-04-1847

  • Endocrinology
    Phosphorylation of Estrogen Receptor α Blocks Its Acetylation and Regulates Estrogen Sensitivity
    Yukun Cui, Mao Zhang, Richard Pestell, Edward M. Curran, Wade V. Welshons and Suzanne A. W. Fuqua
    Cancer Res December 15 2004 64 (24) 9199-9208; DOI:10.1158/0008-5472.CAN-04-2126

Clinical Research

  • Clinical Research
    Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases
    Rajal B. Shah, Rohit Mehra, Arul M. Chinnaiyan, Ronglai Shen, Debashis Ghosh, Ming Zhou, Gary R. MacVicar, Soorynarayana Varambally, Jason Harwood, Tarek A. Bismar, Robert Kim, Mark A. Rubin and Kenneth J. Pienta
    Cancer Res December 15 2004 64 (24) 9209-9216; DOI:10.1158/0008-5472.CAN-04-2442

Epidemiology and Prevention

  • Epidemiology and Prevention
    Caspase Inhibitors, but not c-Jun NH2-Terminal Kinase Inhibitor Treatment, Prevent Cisplatin-Induced Hearing Loss
    Jing Wang, Sabine Ladrech, Remy Pujol, Philippe Brabet, Thomas R. Van De Water and Jean-Luc Puel
    Cancer Res December 15 2004 64 (24) 9217-9224; DOI:10.1158/0008-5472.CAN-04-1581

Meeting Report

  • Meeting Report
    Lymphangiogenesis and Cancer
    Kari Alitalo, Suresh Mohla and Erkki Ruoslahti
    Cancer Res December 15 2004 64 (24) 9225-9229; DOI:10.1158/0008-5472.CAN-04-2475

Corrections

  • Corrections
    Corrections
    Cancer Res December 15 2004 64 (24) 9230-9230; DOI:10.1158/0008-CAN-64-24-CORA

  • Corrections
    Corrections
    Cancer Res December 15 2004 64 (24) 9230-9230; DOI:10.1158/0008-CAN-64-24-CORB

  • Corrections
    Corrections
    Cancer Res December 15 2004 64 (24) 9230-9230; DOI:10.1158/0008-CAN-64-24-CORC

  • Corrections
    Corrections
    Cancer Res December 15 2004 64 (24) 9230-9230; DOI:10.1158/0008-CAN-64-24-CORD

  • Corrections
    Corrections
    Cancer Res December 15 2004 64 (24) 9230-9230; DOI:10.1158/0008-CAN-64-24-CORE

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Cancer Research: 64 (24)
December 2004
Volume 64, Issue 24
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Issue Highlights

  • Early Changes in Protein Expression Detected by Mass Spectrometry Predict Tumor Response to Molecular Therapeutics
  • Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
  • Specific Recognition and Killing of Glioblastoma Multiforme by Interleukin 13-Zetakine Redirected Cytolytic T Cells

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Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
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