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Cancer Research
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About the Cover

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Immunohistological staining of mitotic cells in the ileum of GPX-DKO mice with disrupted both Gpx1 and Gpx2 genes. Mice were injected with bromodeoxyuridine (BrdU) 2 h before euthanasia. Extended from the crypt epithelium, the mitotic cells, which incorporated BrdU for DNA synthesis, were detected with an anti-BrdU antibody. The dark brown staining was produced by streptavidin-peroxidase, which binds to the biotin-conjugated 2nd antibody. The cells were counterstained with hematoxylin. For details, see the article by Chu et al. on p. 962 of this issue.

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Cancer Research: 64 (3)
February 2004
Volume 64, Issue 3
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Issue Highlights

  • Bacteria-Induced Intestinal Cancer in Mice with Disrupted Gpx1 and Gpx2 Genes
  • c-Kit-Targeting Immunotherapy for Hereditary Melanoma in a Mouse Model
  • TIMP-1 Alters Susceptibility to Carcinogenesis
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Copyright © 2021 by the American Association for Cancer Research.

Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

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