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Table of Contents

Proc Amer Assoc Cancer Res, Volume 45, 2004

Best Abstracts Plenary Session

Carcinogenesis 1: Hormonal Carcinogenesis

Carcinogenesis 2: Molecular Carcinogenesis

Carcinogenesis 3: Premalignant Lesions/Oxidative Stress

Carcinogenesis 4: DNA Damage and Repair

Carcinogenesis 5: Animal and In Vitro Models for Carcinogenesis I

Carcinogenesis 6: DNA Damage and Repair I

Carcinogenesis 7: Environmental Carcinogenesis and Tumor Progression

Carcinogenesis 8: Chemical Carcinogenesis

Carcinogenesis 9: Molecular and Viral Carcinogenesis

Carcinogenesis 10: Signal Transduction and Gene Expression

Carcinogenesis 11: Viral Carcinogenesis

Carcinogenesis 12: Mutagenesis

Carcinogenesis 13: Animal and In Vitro Models of Carcinogenesis II

Cellular, Molecular, and Tumor Biology 1: Angiogenesis Inhibitors I

Cellular, Molecular, and Tumor Biology 2: Angiogenesis Inhibitors II

Cellular, Molecular, and Tumor Biology 3: Cell Membrane and Cytoplasmic Signaling Pathways

Cellular, Molecular, and Tumor Biology 15: Cell and Animal Cancer Models

Cellular, Molecular, and Tumor Biology 16: Cell Cycle Control and Checkpoints

Cellular, Molecular, and Tumor Biology 17: Cell Cycle Targeted Therapeutic Agents

Cellular, Molecular, and Tumor Biology 18: Cytoplasmic Signaling

Cellular, Molecular, and Tumor Biology 19: DNA Methylation: Markers

Cellular, Molecular, and Tumor Biology 20: Genomic Instability

Cellular, Molecular, and Tumor Biology 21: Imaging/Tumor Markers

Cellular, Molecular, and Tumor Biology 22: Mechanisms of Transcriptional Regulation II

Cellular, Molecular, and Tumor Biology 23: Senescence, Telomeres, and Telomerase

Cellular, Molecular, and Tumor Biology 24: Transcriptional Control of Cell Survival

Cellular, Molecular, and Tumor Biology 25: Tumor Microenvironment

Cellular, Molecular, and Tumor Biology 26: Chromatin Structure and Transcriptional Regulation

Cellular, Molecular, and Tumor Biology 27: DNA Methylation Inhibition

Cellular, Molecular, and Tumor Biology 28: Functional Genomics

Cellular, Molecular, and Tumor Biology 29: Gene Expression Studies: Technology, Informatics, and Cancer Biology

Cellular, Molecular, and Tumor Biology 30: Genome-wide Analysis in Brain Tumors and Animal Models

Cellular, Molecular, and Tumor Biology 31: Genome-wide Screening for Cancer-related Genes I

Cellular, Molecular, and Tumor Biology 32: Genomics/Proteomics to Study Tumor Progression

Cellular, Molecular, and Tumor Biology 33: Inflammation and Metastasis

Cellular, Molecular, and Tumor Biology 34: Molecular Alterations in Genitourinary Tumors

Cellular, Molecular, and Tumor Biology 35: Proteases and Protease Inhibitors

Cellular, Molecular, and Tumor Biology 36: Therapies against Tumor Invasion and Metastasis

Cellular, Molecular, and Tumor Biology 37: Tobacco-related Malignancies: Tumors of the Head and Neck and Lung

Cellular, Molecular, and Tumor Biology 38: Cancer Genetics: Searching for New Genes and Molecular Markers

Cellular, Molecular, and Tumor Biology 39: DNA Repair and Genomic Instability

Cellular, Molecular, and Tumor Biology 40: Proteases and Tumor Invasion

Cellular, Molecular, and Tumor Biology 41: Angiogenesis II: Novel Agents, Mechanisms, and Targets

Cellular, Molecular, and Tumor Biology 42: Genetic Regulation of Metastasis

Cellular, Molecular, and Tumor Biology 43: Oncogenic Transcription Factors

Cellular, Molecular, and Tumor Biology 44: Senescence and Immortalization

Cellular, Molecular, and Tumor Biology 45: Signaling and Therapeutics

Cellular, Molecular, and Tumor Biology 46: Signaling and Tumor Invasion

Cellular, Molecular, and Tumor Biology 47: Analysis of p53-MDM2-ARF Pathways

Cellular, Molecular, and Tumor Biology 48: Angiogenesis I: Inhibitors of VEGF and VEGF-Receptors

Cellular, Molecular, and Tumor Biology 49: Cyclins and Cyclin-dependent Kinases

Cellular, Molecular, and Tumor Biology 50: DNA Damage and Repair II

Cellular, Molecular, and Tumor Biology 51: DNA Damage and Repair III

Cellular, Molecular, and Tumor Biology 52: Molecular Alterations in Prostate Cancer

Cellular, Molecular, and Tumor Biology 53: Molecular Markers I

Cellular, Molecular, and Tumor Biology 54: Pediatric Oncology

Cellular, Molecular, and Tumor Biology 55: Receptor Signaling

Cellular, Molecular, and Tumor Biology 56: Regulatory Mechanisms in Skin Tumorigenesis

Cellular, Molecular, and Tumor Biology 57: Stem Cell Biology

Cellular, Molecular, and Tumor Biology 58: Transcriptional Control of Cellular Activities

Cellular, Molecular, and Tumor Biology 58: Transcriptional Control of Cellular Activities

Cellular, Molecular, and Tumor Biology 59: Tumor Classification and Genome and Transcriptome Scanning

Cellular, Molecular, and Tumor Biology 59: Tumor Classification and Genome and Transcriptome Scanning

Cellular, Molecular, and Tumor Biology 60: Angiogenic Gene Expression in Malignancy

Cellular, Molecular, and Tumor Biology 61: Bioinformatics: Genomics, Transcriptomics, and Systems Biology of Cancer

Cellular, Molecular, and Tumor Biology 62: Biomarkers for Metastasis

Cellular, Molecular, and Tumor Biology 63: Biomarkers for Tumor Progression

Cellular, Molecular, and Tumor Biology 64: Bone Metastasis

Cellular, Molecular, and Tumor Biology 65: Cell Surface Death Pathways I

Cellular, Molecular, and Tumor Biology 66: Cell Surface Death Pathways II

Cellular, Molecular, and Tumor Biology 67: Gene Regulation and Tumor Invasion

Cellular, Molecular, and Tumor Biology 68: Genome-wide Screening for Cancer-related Genes II

Cellular, Molecular, and Tumor Biology 69: MAP Kinase Cascade Signaling

Cellular, Molecular, and Tumor Biology 70: Molecular Alterations in Mammary Tumorigenesis

Cellular, Molecular, and Tumor Biology 71: PI3K/ AKT Signaling

Cellular, Molecular, and Tumor Biology 72: Proteomic Pattern Analysis for Cancer Diagnosis and Treatment

Cellular, Molecular, and Tumor Biology 73: Regulation of TRAIL-induced Apoptosis

Cellular, Molecular, and Tumor Biology 74: Regulators of Increased Angiogenesis

Cellular, Molecular, and Tumor Biology 75: siRNA and Gene Silencing

Cellular, Molecular, and Tumor Biology 76: Therapeutic and Diagnostic Marker Discovery Using Proteomics

Cellular, Molecular, and Tumor Biology 77: Cytoplasmic and Nuclear Signaling

Cellular, Molecular, and Tumor Biology 78: Host and Tumor Genomic Instability

Cellular, Molecular, and Tumor Biology 79: Ubiquitin Ligases and Associated Kinases at Key Cell Cycle Checkpoints

Cellular, Molecular, and Tumor Biology 80: Angiogenesis Inhibitors III

Cellular, Molecular, and Tumor Biology 81: Apoptosis-inducing Agents

Cellular, Molecular, and Tumor Biology 82: Cell and Tissue Radiation Biology

Cellular, Molecular, and Tumor Biology 83: DNA Methylation and Chromatin

Cellular, Molecular, and Tumor Biology 84: DNA Methylation: New Genes

Cellular, Molecular, and Tumor Biology 84: DNA Methylation: New Genes

Cellular, Molecular, and Tumor Biology 85: Functional Analyses of Nuclear Oncogenes and Tumor Suppressors

Cellular, Molecular, and Tumor Biology 86: Gene Expression

Cellular, Molecular, and Tumor Biology 87: Genetic and Epigenetic Changes in Cancer

Cellular, Molecular, and Tumor Biology 88: Molecular Markers II

Cellular, Molecular, and Tumor Biology 89: Mouse Models of Prostate and Gastrointestinal Cancers

Cellular, Molecular, and Tumor Biology 89: Mouse Models of Prostate and Gastrointestinal Cancers

Cellular, Molecular, and Tumor Biology 90: Non-ionizing Radiation

Cellular, Molecular, and Tumor Biology 91: Receptor Tyrosine Kinase Signaling

Cellular, Molecular, and Tumor Biology 92: Regulation of Apoptosis I

Cellular, Molecular, and Tumor Biology 93: Signaling and Therapeutics II

Cellular, Molecular, and Tumor Biology 94: Advances in Proteomics Applied to Cancer Detection and Treatment

Cellular, Molecular, and Tumor Biology 95: Angiogenesis Mechanisms and Microenvironment

Cellular, Molecular, and Tumor Biology 95: Angiogenesis Mechanisms and Microenvironment

Cellular, Molecular, and Tumor Biology 96:: Bioinformatics and Cancer: Tools, Resources, and Biology

Cellular, Molecular, and Tumor Biology 97: Cell Surface Receptor Signaling

Cellular, Molecular, and Tumor Biology 98: Mechanisms of Apoptosis

Cellular, Molecular, and Tumor Biology 99: DNA Methylation Profiles

Cellular, Molecular, and Tumor Biology 100: Activation of Apoptosis by Novel Therapeutic Agents

Cellular, Molecular, and Tumor Biology 101: Adhesion and Signaling in Cancer Progression

Cellular, Molecular, and Tumor Biology 102: Angiogenesis III

Cellular, Molecular, and Tumor Biology 103: Apoptosis Detection and Regulation

Cellular, Molecular, and Tumor Biology 104: Kinase-mediated Cell Survival and Apoptosis

Cellular, Molecular, and Tumor Biology 105: Matrix and Adhesion in Cancer Metastasis I

Cellular, Molecular, and Tumor Biology 106: Matrix and Adhesion in Cancer Metastasis II

Cellular, Molecular, and Tumor Biology 107: Molecular Alterations in Gastrointestinal Tumor Formation

Cellular, Molecular, and Tumor Biology 108: Mouse Models of Human Cancer

Cellular, Molecular, and Tumor Biology 109: Preclinical Science and Imaging in Cancer Models

Cellular, Molecular, and Tumor Biology 110: Protein Kinase C Signaling

Cellular, Molecular, and Tumor Biology 111: Regulation of Apoptosis II

Cellular, Molecular, and Tumor Biology 112: Signaling and Therapeutics III

Cellular, Molecular, and Tumor Biology 113: Cytoplasmic Signaling by Oncogenes and Tumor Suppressors

Cellular, Molecular, and Tumor Biology 114: Molecular and Cellular Determinants of Radiation Response

Cellular, Molecular, and Tumor Biology 115: Nuclear Oncogenes and Tumor Suppressors

Cellular, Molecular, and Tumor Biology 116: Single and Multiple Gene Alterations in Murine Cancer Models

Cellular, Molecular, and Tumor Biology 117: Therapeutic Applications Based on Apoptotic Pathways

Chemistry 1: Chemical Topics in Drug Therapy, Radiation Therapy, Imaging, and Structure Biology

Chemistry 2: Chemical Aspects of Carcinogenesis

Chemistry 3: DNA as a Target for Drugs and Carcinogens

Chemistry 4: SAR and Structural Biology Studies of Drug Candidates

Chemistry 5: Proteomics and Chemistry

Clinical Research 1: Drug Resistance, Pharmacogenomics, and Pharmacokinetics

Clinical Research 2: Molecular Diagnosis and Prognosis I

Clinical Research 3: Molecular Classification of Tumors

Clinical Research 4: Molecular Diagnosis and Prognosis II

Clinical Research 5: Emerging Concepts and Targets in Immunotherapy

Clinical Research 6: Novel Prognostic and Predictive Factors

Clinical Research 7: Molecular Markers of Metastasis and Progression

Clinical Research 8: Laboratory Correlates/New Targeted Agents/Methodology for New Study Design

Clinical Research 9: Molecular Detection of Metastasis and Genetic Alteration in Cancer

Clinical Research 10: Early Detection: Strategies and Technologies

Clinical Research 10:: Early Detection: Strategies and Technologies

Clinical Research 11: Clinical Investigations II: Gastrointestinal Cancers/Head and Neck Cancers/Hormone-related Cancers/ Leukemia and Lymphoma

Clinical Research 12: Clinical Investigations III: Lung Cancer/Ovarian and Other Gynecologic Cancers

Clinical Research 13: Clinical Investigations IV: Prostate and Other Genitourinary Cancers

Clinical Research 14: Clinical Pharmacology/Pharmacogenomics

Clinical Research 15: Clinical Investigations V: Brain and Other CNS Tumors/Breast Cancer/Melanoma

Clinical Research 16: Molecular and Morphologic Tumor Staging/Imaging

Clinical Research 17: Global Molecular Classification and Diagnosis

Educational Session: Advances in High-Throughput Genotyping

Educational Session: Biologic Agents as Radiation Response Modifiers

Educational Session: Chemical Biology in Anticancer Drug Discovery

Educational Session: Chromatin Structure and Function in Cancer

Educational Session: Hypoxia: Impact on Cancer Biology

Educational Session: Molecular Imaging Strategies

Educational Session: RNA Interference: A Tool for Gene Silencing

Educational Session: Registration Strategies in Cancer Drug Development: Opportunities and Challenges

Educational Session: Research Paradigms in Anticancer Drug Discovery and Development

Educational Session: Stem Cells and Cancer

Educational Session: Structural Biology and Its Practical Aspects in Drug Discovery

Educational Session: Studying Genetic Modifiers in Experimental and Human Cancer

Educational Session: Targeting Signal Transduction Pathways

Educational Session: Zebrafish as an Animal Model in Cancer Research

Endocrinology 1: Endocrinology I

Endocrinology 2: Endocrinology II

Endocrinology 3: Endocrinology III

Endocrinology 4: Endocrinology IV

Endocrinology 5: Endocrinology V

Epidemiology 1: Viral, Bacterial, and Dietary Exposures

Epidemiology 2: Epidemiology of Breast and Prostate Cancer

Epidemiology 3: Immune Response and Exposure Modifying Genes in Diverse Neoplasms

Epidemiology 4: DNA Repair Genotype/Phenotype II

Epidemiology 5: Biomarkers of Human Exposure to Carcinogens

Epidemiology 6: Endogenous and Exogenous Factors in Breast and Prostate Cancer

Epidemiology 7: DNA Repair Genotype/Phenotype I

Epidemiology 8: Methods, Genotype/Phenotype and Carcinogen Metabolism Genes

Epidemiology 9: Risk Factors and Modeling

Epidemiology 10: Smoking and Cancer: Lung, Head and Neck, and Bladder Cancer

Epidemiology 11: Genetic Epidemiology of Breast, Prostate, and Gynecologic Cancers: Hormone and Carcinogen Metabolism

Epidemiology 12: Polymorphisms in Diverse Genes Associated with Gastrointestinal Lesions

Epidemiology 13: Genetic Susceptibility to Squamous and Transitional Cell Cancers

Experimental and Molecular Therapeutics 1: ABC Transporters in Drug Resistance

Experimental and Molecular Therapeutics 2: Drug Accumulation and Metabolism as Mechanisms of Drug Resistance

Experimental and Molecular Therapeutics 3: Investigational Combinations/Modulators I

Experimental and Molecular Therapeutics 4: Mechanisms of Action

Experimental and Molecular Therapeutics 5: Molecular Profiling of Drug Resistance

Experimental and Molecular Therapeutics 6: Novel Delivery Strategies

Experimental and Molecular Therapeutics 7: Cellular Responses to Alkylating Agents

Experimental and Molecular Therapeutics 8: Diagnostic Markers, Imaging, and Microarrays

Experimental and Molecular Therapeutics 9: Gene Therapy I

Experimental and Molecular Therapeutics 10: Novel Mechanisms of Drug Resistance

Experimental and Molecular Therapeutics 11: Specific Immune Mechanisms and Cancer Vaccines: Clinical Studies

Experimental and Molecular Therapeutics 12: New Targets, Agents, and Delivery Strategies

Experimental and Molecular Therapeutics 13: Novel Therapeutic Agents I

Experimental and Molecular Therapeutics 14: Investigational Combinations/Modulators II

Experimental and Molecular Therapeutics 15: Molecular Pharmacology, Pharmacokinetics and Pharmacogenomics

Experimental and Molecular Therapeutics 16: Novel Agents: Targets and Mechanisms

Experimental and Molecular Therapeutics 17: Novel Screens/Targets and Dosing Approaches

Experimental and Molecular Therapeutics 18: Pharmacogenomics, Preclinical Toxicology, Pharmacokinetics

Experimental and Molecular Therapeutics 19: Reversing or Overcoming Drug Resistance

Experimental and Molecular Therapeutics 20: Gene Expression Profiling of Drug Action

Experimental and Molecular Therapeutics 21: Cell Cycle Checkpoint and Kinase Inhibition

Experimental and Molecular Therapeutics 22: Novel Strategies for Gene Delivery

Experimental and Molecular Therapeutics 23: Histone Deacetylase Inhibitors

Experimental and Molecular Therapeutics 24: Novel Mechanisms of Drug Resistance and Functional Characterization

Experimental and Molecular Therapeutics 25: Apoptotic Pathways and the Immune System

Experimental and Molecular Therapeutics 26: Molecular Targets of Antimetabolites

Experimental and Molecular Therapeutics 27: Natural Products

Experimental and Molecular Therapeutics 28: Novel Targets and Approaches for Angiogenesis and Signaling Pathways

Experimental and Molecular Therapeutics 29: Novel Therapeutic Agents II

Experimental and Molecular Therapeutics 30: Target Identification

Experimental and Molecular Therapeutics 31: Topoisomerase, Telomerase, and Nucleosides/Nucleotides

Experimental and Molecular Therapeutics 32: Cellular Pharmacology and Pharmacogenomics

Experimental and Molecular Therapeutics 33: Gene Therapy II

Experimental and Molecular Therapeutics 34: Genes, Drugs, and Novel Agents

Experimental and Molecular Therapeutics 35: Preclinical Models/Pharmacology/Mechanisms

Experimental and Molecular Therapeutics 36: Signal Transduction Inhibitors

Experimental and Molecular Therapeutics 37: Signaling Targets

Experimental and Molecular Therapeutics 38: Novel Therapeutic Agents III: Signaling Inhibitors

Experimental and Molecular Therapeutics 39: Novel Therapeutic Agents IV: Small Molecule Inhibitors

Experimental and Molecular Therapeutics 40: Proteosome Inhibition and Histone Deacetylase Inhibitors

Experimental and Molecular Therapeutics 41: Antiangiogenesis

Experimental and Molecular Therapeutics 41: Antiangiogenesis

Experimental and Molecular Therapeutics 42: Cell and Stroma-directed New Agents

Experimental and Molecular Therapeutics 43: Gene Therapy III

Experimental and Molecular Therapeutics 44: Platinum Compounds/Antimetabolites/Taxanes

Experimental and Molecular Therapeutics 45: Small Molecules: Signaling and Apoptosis Targets

Experimental and Molecular Therapeutics 46: Cell Signaling Inhibitors

Experimental and Molecular Therapeutics 47: Cellular Responses to Anticancer Drugs

Experimental and Molecular Therapeutics 48: Growth Factor Receptors as Therapeutic Targets

Experimental and Molecular Therapeutics 49: Molecular Targeted Agents

Experimental and Molecular Therapeutics 50: New Approaches to Classic Targets

Experimental and Molecular Therapeutics 51: Pharmacokinetics and Pharmacodynamics

Experimental and Molecular Therapeutics 52: Tubulin-targeted Agents

Experimental and Molecular Therapeutics 53: Microtubule Inhibitors

Experimental and Molecular Therapeutics 54: Small Molecules: Cell Cycle and Signaling Inhibitors

Immunology/Tumor Immunobiology 1: Lymphokines, Cytokines, and Growth Factors in Tumor Immunity I

Immunology/Tumor Immunobiology 2: Tumors and the Immune System: Immunotherapy and Immunomodulation I

Immunology/Tumor Immunobiology 3: Specific Immunomechanisms and Cancer Vaccines: Basic Studies I

Immunology/Tumor Immunobiology 4: Specific Immunomechanisms and Cancer Vaccines: Basic Studies II

Immunology/Tumor Immunobiology 5: Tumors and the Immune System: Immunotherapy and Immunomodulation II

Immunology/Tumor Immunobiology 6: Molecular and Cellular Mechanisms of Antitumor Immunity

Immunology/Tumor Immunobiology 7: Innovative Approaches to Immunotherapy of Tumors

Immunology/Tumor Immunobiology 8: Lymphokines, Cytokines, and Growth Factors in Tumor Immunity II

Immunology/Tumor Immunobiology 9: Specific Immunomechanisms and Cancer Vaccines: Basic Studies III

Immunology/Tumor Immunobiology 10: Cancer Vaccines: Preclinical Studies

Immunology/Tumor Immunobiology 11: Tumor Antigens and Animal Models for Immunotherapy I

Immunology/Tumor Immunobiology 12: Tumor Antigens and Animal Models for Immunotherapy II

Integrated Session 1: Growth Factors and Antibodies in Tumor Immunotherapy

Integrated Session 2: Cell Signaling and Apoptosis after Radiation

Integrated Session 3: Clinical Cancer Genetics

Integrated Session 4: Clinical Prevention Studies

Integrated Session 5: Modification of Radiation Sensitivity

Integrated Session 6: Immunotherapy and Combined Modality Approaches

Integrated Session 7: Pediatric Oncology

Integrated Session 8: Radiation: Normal Tissue Damage, Protectors, and Predictive Assays

Integrated Session 9: Racial and Ethnic Minorities and the Medically Underserved: Multidisciplinary Research into Biology, Outcomes, and Disparities

Integrated Session 10: Human Prevention/Screening Studies

Integrated Session 11: Proteomics

Opening Plenary Session: Targeting the Conquest of Cancer through Conceptual Integration and Innovation

Prevention Research 1: Chemoprevention Studies I

Prevention Research 2: Biological and Biochemical Mechanisms in Prevention

Prevention Research 3: Molecular Targets for Cancer Prevention: Development of New Agents

Prevention Research 5: Chemoprevention Studies II

Prevention Research 6: Molecular Markers in Prevention Research

Prevention Research 7: Diet and Cancer

Prevention Research 8: Mechanistic Pathways Modulated by Natural Products

Prevention Research 9: New Agents and Mechanisms in Chemoprevention of Prostate and Breast Cancer

Prevention Research 10: Biomarkers and Intervention Studies

Supportive Care and Survivorship Research 1: Psychosocial Research in Cancer

Symposium: Cellular and Molecular Determinants of Metastasis

Symposium: Challenges for Integrating Targeted Therapies

Symposium: DNA Damage Signaling

Symposium: Genetic Model Systems to Dissect Cancer

Symposium: Genetic Modifiers of Cancer Risk

Symposium: Genomic and Chromosomal Instability

Symposium: Nuclear Receptors and Cancer Prevention

Symposium: Obesity, Metabolism and Cancer

Symposium: Outside-In Signaling in Cancer

Symposium: Pharmacogenomics and Response Prediction

Symposium: Role of DNA Repair Genotype and Phenotype in Cancer Susceptibility

Symposium: Systems Biology of Cancer: The Tumor as an Organ

Symposium: The Ubiquitin-Proteasome System and Cancer