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Table of Contents

Reviews

  • Reviews
    Human T-Cell Leukemia Virus Type I at Age 25: A Progress Report
    Masao Matsuoka and Kuan-Teh Jeang
    Cancer Res June 1 2005 65 (11) 4467-4470; DOI:10.1158/0008-5472.CAN-05-0559

  • Reviews
    Tumor Dormancy and MYC Inactivation: Pushing Cancer to the Brink of Normalcy
    Catherine M. Shachaf and Dean W. Felsher
    Cancer Res June 1 2005 65 (11) 4471-4474; DOI:10.1158/0008-5472.CAN-05-1172

Meeting Report

  • Meeting Report
    Meeting Report: The International Conference on Tumor Progression and Therapeutic Resistance
    Wafik S. El-Deiry
    Cancer Res June 1 2005 65 (11) 4475-4484; DOI:10.1158/0008-5472.CAN-05-0620

Priority Reports

  • Priority Reports
    Tumor Suppressor VDUP1 Increases p27kip1 Stability by Inhibiting JAB1
    Jun-Ho Jeon, Kee-Nyung Lee, Chae Young Hwang, Ki-Sun Kwon, Kwan-Hee You and Inpyo Choi
    Cancer Res June 1 2005 65 (11) 4485-4489; DOI:10.1158/0008-5472.CAN-04-2271

  • Priority Reports
    Genetic Modeling of Human Rhabdomyosarcoma
    Corinne M. Linardic, Diane L. Downie, Stephen Qualman, Rex C. Bentley and Christopher M. Counter
    Cancer Res June 1 2005 65 (11) 4490-4495; DOI:10.1158/0008-5472.CAN-04-3194

  • Priority Reports
    The Prostaglandin E2 Receptor EP2 Is Required for Cyclooxygenase 2–Mediated Mammary Hyperplasia
    Sung-Hee Chang, Youxi Ai, Richard M. Breyer, Timothy F. Lane and Timothy Hla
    Cancer Res June 1 2005 65 (11) 4496-4499; DOI:10.1158/0008-5472.CAN-05-0129

  • Priority Reports
    In vitro Activity of Bcr-Abl Inhibitors AMN107 and BMS-354825 against Clinically Relevant Imatinib-Resistant Abl Kinase Domain Mutants
    Thomas O'Hare, Denise K. Walters, Eric P. Stoffregen, Taiping Jia, Paul W. Manley, Jürgen Mestan, Sandra W. Cowan-Jacob, Francis Y. Lee, Michael C. Heinrich, Michael W.N. Deininger and Brian J. Druker
    Cancer Res June 1 2005 65 (11) 4500-4505; DOI:10.1158/0008-5472.CAN-05-0259

  • Priority Reports
    A Mouse Model for the Carney Complex Tumor Syndrome Develops Neoplasia in Cyclic AMP–Responsive Tissues
    Lawrence S. Kirschner, Donna F. Kusewitt, Ludmila Matyakhina, William H. Towns II, J. Aidan Carney, Heiner Westphal and Constantine A. Stratakis
    Cancer Res June 1 2005 65 (11) 4506-4514; DOI:10.1158/0008-5472.CAN-05-0580

  • Priority Reports
    Akt Phosphorylates Tal1 Oncoprotein and Inhibits Its Repressor Activity
    Alexey Palamarchuk, Alexey Efanov, Vadim Maximov, Rami I. Aqeilan, Carlo M. Croce and Yuri Pekarsky
    Cancer Res June 1 2005 65 (11) 4515-4519; DOI:10.1158/0008-5472.CAN-05-0751

  • Priority Reports
    The PKCα-D294G Mutant Found in Pituitary and Thyroid Tumors Fails to Transduce Extracellular Signals
    Yimin Zhu, Qihan Dong, Bee Jen Tan, Wee Guan Lim, Shufeng Zhou and Wei Duan
    Cancer Res June 1 2005 65 (11) 4520-4524; DOI:10.1158/0008-5472.CAN-04-4506

  • Priority Reports
    Characterization of the Mismatch Repair Defect in the Human Lymphoblastoid MT1 Cells
    Marta Szadkowski, Ingram Iaccarino, Karl Heinimann, Giancarlo Marra and Josef Jiricny
    Cancer Res June 1 2005 65 (11) 4525-4529; DOI:10.1158/0008-5472.CAN-05-0080

Molecular Biology, Pathobiology, and Genetics

  • Molecular Biology, Pathobiology, and Genetics
    Transcriptional Programs following Genetic Alterations in p53, INK4A, and H-Ras Genes along Defined Stages of Malignant Transformation
    Michael Milyavsky, Yuval Tabach, Igor Shats, Neta Erez, Yehudit Cohen, Xiaohu Tang, Marina Kalis, Ira Kogan, Yosef Buganim, Naomi Goldfinger, Doron Ginsberg, Curtis C. Harris, Eytan Domany and Varda Rotter
    Cancer Res June 1 2005 65 (11) 4530-4543; DOI:10.1158/0008-5472.CAN-04-3880

  • Molecular Biology, Pathobiology, and Genetics
    Salivary Gland Tumors in Transgenic Mice with Targeted PLAG1 Proto-Oncogene Overexpression
    Jeroen Declercq, Frederik Van Dyck, Caroline V. Braem, Isabelle C. Van Valckenborgh, Marianne Voz, Michel Wassef, Luc Schoonjans, Boudewijn Van Damme, Laurence Fiette and Wim J.M. Van de Ven
    Cancer Res June 1 2005 65 (11) 4544-4553; DOI:10.1158/0008-5472.CAN-04-4041

  • Molecular Biology, Pathobiology, and Genetics
    Alteration of SMRT Tumor Suppressor Function in Transformed Non-Hodgkin Lymphomas
    Lynda Song, Andrei Zlobin, Pushpankur Ghoshal, Qing Zhang, Christiane Houde, Sanne Weijzen, Qun Jiang, Elizabeth Nacheva, Danny Yagan, Eric Davis, Sylvie Galiegue-Zouitina, Daniel Catovsky, Thomas Grogan, Richard I. Fisher, Lucio Miele and Lionel J. Coignet
    Cancer Res June 1 2005 65 (11) 4554-4561; DOI:10.1158/0008-5472.CAN-04-4108

  • Molecular Biology, Pathobiology, and Genetics
    Functional Analysis of PIK3CA Gene Mutations in Human Colorectal Cancer
    Tsuneo Ikenoue, Fumihiko Kanai, Yohko Hikiba, Toshiyuki Obata, Yasuo Tanaka, Jun Imamura, Miki Ohta, Amarsanaa Jazag, Bayasi Guleng, Keisuke Tateishi, Yoshinari Asaoka, Masayuki Matsumura, Takao Kawabe and Masao Omata
    Cancer Res June 1 2005 65 (11) 4562-4567; DOI:10.1158/0008-5472.CAN-04-4114

  • Molecular Biology, Pathobiology, and Genetics
    Liver-Specific pRB Loss Results in Ectopic Cell Cycle Entry and Aberrant Ploidy
    Christopher N. Mayhew, Emily E. Bosco, Sejal R. Fox, Tomohisa Okaya, Pheruza Tarapore, Sandy J. Schwemberger, George F. Babcock, Alex B. Lentsch, Kenji Fukasawa and Erik S. Knudsen
    Cancer Res June 1 2005 65 (11) 4568-4577; DOI:10.1158/0008-5472.CAN-04-4221

  • Molecular Biology, Pathobiology, and Genetics
    PCOTH, a Novel Gene Overexpressed in Prostate Cancers, Promotes Prostate Cancer Cell Growth through Phosphorylation of Oncoprotein TAF-Iβ/SET
    Yoshio Anazawa, Hidewaki Nakagawa, Mutsuo Furihara, Shingo Ashida, Kenji Tamura, Hiroki Yoshioka, Taro Shuin, Tomoaki Fujioka, Toyomasa Katagiri and Yusuke Nakamura
    Cancer Res June 1 2005 65 (11) 4578-4586; DOI:10.1158/0008-5472.CAN-04-4564

  • Molecular Biology, Pathobiology, and Genetics
    LMO3 Interacts with Neuronal Transcription Factor, HEN2, and Acts as an Oncogene in Neuroblastoma
    Mineyoshi Aoyama, Toshinori Ozaki, Hiroyuki Inuzuka, Daihachiro Tomotsune, Junko Hirato, Yoshiaki Okamoto, Hisashi Tokita, Miki Ohira and Akira Nakagawara
    Cancer Res June 1 2005 65 (11) 4587-4597; DOI:10.1158/0008-5472.CAN-04-4630

  • Molecular Biology, Pathobiology, and Genetics
    Tumor Suppressor Activity and Epigenetic Inactivation of Hepatocyte Growth Factor Activator Inhibitor Type 2/SPINT2 in Papillary and Clear Cell Renal Cell Carcinoma
    Mark R. Morris, Dean Gentle, Mahera Abdulrahman, Esther N. Maina, Kunal Gupta, Rosamonde E. Banks, Michael S. Wiesener, Takeshi Kishida, Masahiro Yao, Bin Teh, Farida Latif and Eamonn R. Maher
    Cancer Res June 1 2005 65 (11) 4598-4606; DOI:10.1158/0008-5472.CAN-04-3371

  • Molecular Biology, Pathobiology, and Genetics
    Mutations in Two Short Noncoding Mononucleotide Repeats in Most Microsatellite-Unstable Colorectal Cancers
    Tuija Hienonen, Heli Sammalkorpi, Susa Enholm, Pia Alhopuro, Thomas D. Barber, Rainer Lehtonen, Nina N. Nupponen, Heli Lehtonen, Reijo Salovaara, Jukka-Pekka Mecklin, Heikki Järvinen, Riitta Koistinen, Diego Arango, Virpi Launonen, Bert Vogelstein, Auli Karhu and Lauri A. Aaltonen
    Cancer Res June 1 2005 65 (11) 4607-4613; DOI:10.1158/0008-5472.CAN-05-0165

Cell and Tumor Biology

  • Cell and Tumor Biology
    Tachyplesin Activates the Classic Complement Pathway to Kill Tumor Cells
    Jinguo Chen, Xue-Ming Xu, Charles B. Underhill, Shanmin Yang, Luping Wang, Yixin Chen, Shuigen Hong, Karen Creswell and Lurong Zhang
    Cancer Res June 1 2005 65 (11) 4614-4622; DOI:10.1158/0008-5472.CAN-04-2253

  • Cell and Tumor Biology
    EphB4 Expression and Biological Significance in Prostate Cancer
    Guangbin Xia, S. Ram Kumar, Rizwan Masood, Sutao Zhu, Ramchandra Reddy, Valery Krasnoperov, David I. Quinn, Susan M. Henshall, Robert L. Sutherland, Jacek K. Pinski, Siamak Daneshmand, Maurizio Buscarini, John P. Stein, Chen Zhong, Daniel Broek, Pradip Roy-Burman and Parkash S. Gill
    Cancer Res June 1 2005 65 (11) 4623-4632; DOI:10.1158/0008-5472.CAN-04-2667

  • Cell and Tumor Biology
    EWS-FLI1 Fusion Protein Up-regulates Critical Genes in Neural Crest Development and Is Responsible for the Observed Phenotype of Ewing's Family of Tumors
    Siwen Hu-Lieskovan, Jingsong Zhang, Lingtao Wu, Hiroyuki Shimada, Deborah E. Schofield and Timothy J. Triche
    Cancer Res June 1 2005 65 (11) 4633-4644; DOI:10.1158/0008-5472.CAN-04-2857

  • Cell and Tumor Biology
    Hypersialylation of β1 Integrins, Observed in Colon Adenocarcinoma, May Contribute to Cancer Progression by Up-regulating Cell Motility
    Eric C. Seales, Gustavo A. Jurado, Brian A. Brunson, John K. Wakefield, Andra R. Frost and Susan L. Bellis
    Cancer Res June 1 2005 65 (11) 4645-4652; DOI:10.1158/0008-5472.CAN-04-3117

  • Cell and Tumor Biology
    Tumor-Stromal Interaction through the Estrogen-Signaling Pathway in Human Breast Cancer
    Yuri Yamaguchi, Hiroyuki Takei, Kimito Suemasu, Yasuhito Kobayashi, Masafumi Kurosumi, Nobuhiro Harada and Shin-ichi Hayashi
    Cancer Res June 1 2005 65 (11) 4653-4662; DOI:10.1158/0008-5472.CAN-04-3236

  • Cell and Tumor Biology
    Kringle 5 of Human Plasminogen Induces Apoptosis of Endothelial and Tumor Cells through Surface-Expressed Glucose-Regulated Protein 78
    Don J. Davidson, Catherine Haskell, Sandy Majest, Abdullah Kherzai, David A. Egan, Karl A. Walter, Andrew Schneider, Earl F. Gubbins, Larry Solomon, Zhebo Chen, Rick Lesniewski and Jack Henkin
    Cancer Res June 1 2005 65 (11) 4663-4672; DOI:10.1158/0008-5472.CAN-04-3426

  • Cell and Tumor Biology
    Interleukin 6 Supports the Maintenance of p53 Tumor Suppressor Gene Promoter Methylation
    David R. Hodge, Benjamin Peng, James C. Cherry, Elaine M. Hurt, Stephen D. Fox, James A. Kelley, David J. Munroe and William L. Farrar
    Cancer Res June 1 2005 65 (11) 4673-4682; DOI:10.1158/0008-5472.CAN-04-3589

  • Cell and Tumor Biology
    Centromere Protein H Is Up-regulated in Primary Human Colorectal Cancer and Its Overexpression Induces Aneuploidy
    Takeshi Tomonaga, Kazuyuki Matsushita, Masumi Ishibashi, Masahiko Nezu, Hideaki Shimada, Takenori Ochiai, Kinya Yoda and Fumio Nomura
    Cancer Res June 1 2005 65 (11) 4683-4689; DOI:10.1158/0008-5472.CAN-04-3613

  • Cell and Tumor Biology
    The Proinflammatory Cytokine Interleukin 1β and Hypoxia Cooperatively Induce the Expression of Adrenomedullin in Ovarian Carcinoma Cells through Hypoxia Inducible Factor 1 Activation
    Stilla Frede, Patricia Freitag, Teresa Otto, Christina Heilmaier and Joachim Fandrey
    Cancer Res June 1 2005 65 (11) 4690-4697; DOI:10.1158/0008-5472.CAN-04-3877

  • Cell and Tumor Biology
    Requirement for Focal Adhesion Kinase in the Early Phase of Mammary Adenocarcinoma Lung Metastasis Formation
    Maroesja J. van Nimwegen, Saertje Verkoeijen, Liesbeth van Buren, Danny Burg and Bob van de Water
    Cancer Res June 1 2005 65 (11) 4698-4706; DOI:10.1158/0008-5472.CAN-04-4126

  • Cell and Tumor Biology
    Cytochrome P450 2J2 Promotes the Neoplastic Phenotype of Carcinoma Cells and Is Up-regulated in Human Tumors
    Jian-Gang Jiang, Chun-Lian Chen, Jeffrey W. Card, Shilin Yang, Ji-Xiong Chen, Xiang-Ning Fu, Yao-Gui Ning, Xiao Xiao, Darryl C. Zeldin and Dao Wen Wang
    Cancer Res June 1 2005 65 (11) 4707-4715; DOI:10.1158/0008-5472.CAN-04-4173

  • Cell and Tumor Biology
    Antivascular Therapy of Human Follicular Thyroid Cancer Experimental Bone Metastasis by Blockade of Epidermal Growth Factor Receptor and Vascular Growth Factor Receptor Phosphorylation
    Maher Nabil Younes, Orhan Gazi Yigitbasi, Young Wook Park, Sun-Jin Kim, Samar A. Jasser, Valerie Stone Hawthorne, Yasemin Dakak Yazici, Mahitosh Mandal, Benjamin Nebiyou Bekele, Corazon D. Bucana, Isaiah J. Fidler and Jeffrey N. Myers
    Cancer Res June 1 2005 65 (11) 4716-4727; DOI:10.1158/0008-5472.CAN-04-4196

  • Cell and Tumor Biology
    A Secreted Form of ADAM9 Promotes Carcinoma Invasion through Tumor-Stromal Interactions
    Antonio Mazzocca, Roberto Coppari, Raffaella De Franco, Je-Yoel Cho, Towia A. Libermann, Massimo Pinzani and Alex Toker
    Cancer Res June 1 2005 65 (11) 4728-4738; DOI:10.1158/0008-5472.CAN-04-4449

  • Cell and Tumor Biology
    Vascular Endothelial Cell Growth Factor Receptor 3–Mediated Activation of Lymphatic Endothelium Is Crucial for Tumor Cell Entry and Spread via Lymphatic Vessels
    Yulong He, Iiro Rajantie, Katri Pajusola, Michael Jeltsch, Tanja Holopainen, Seppo Yla-Herttuala, Thomas Harding, Karin Jooss, Takashi Takahashi and Kari Alitalo
    Cancer Res June 1 2005 65 (11) 4739-4746; DOI:10.1158/0008-5472.CAN-04-4576

  • Cell and Tumor Biology
    BRCA2 Suppresses Cell Proliferation via Stabilizing MAGE-D1
    Xin-xia Tian, Deepak Rai, Jun Li, Chaozhong Zou, Yujie Bai, David Wazer, Vimla Band and Qingshen Gao
    Cancer Res June 1 2005 65 (11) 4747-4753; DOI:10.1158/0008-5472.CAN-05-0018

  • Cell and Tumor Biology
    A Role for ADAM12 in Breast Tumor Progression and Stromal Cell Apoptosis
    Marie Kveiborg, Camilla Fröhlich, Reidar Albrechtsen, Verena Tischler, Nikolaj Dietrich, Peter Holck, Pauliina Kronqvist, Fritz Rank, Arthur M. Mercurio and Ulla M. Wewer
    Cancer Res June 1 2005 65 (11) 4754-4761; DOI:10.1158/0008-5472.CAN-05-0262

  • Cell and Tumor Biology
    CCAAT/Enhancer-Binding Protein δ: A Molecular Target of 1,25-Dihydroxyvitamin D3 in Androgen-Responsive Prostate Cancer LNCaP Cells
    Takayuki Ikezoe, Sigal Gery, Dong Yin, James O'Kelly, Lise Binderup, Nathan Lemp, Hirokuni Taguchi and H. Phillip Koeffler
    Cancer Res June 1 2005 65 (11) 4762-4768; DOI:10.1158/0008-5472.CAN-03-3619

  • Cell and Tumor Biology
    Chemopreventive Effect of Peroxisome Proliferator–Activated Receptor γ on Gastric Carcinogenesis in Mice
    Jie Lu, Kazuhiro Imamura, Sachiyo Nomura, Ken-ichi Mafune, Atsushi Nakajima, Takashi Kadowaki, Naoto Kubota, Yasuo Terauchi, Genichiro Ishii, Atsushi Ochiai, Hiroyasu Esumi and Michio Kaminishi
    Cancer Res June 1 2005 65 (11) 4769-4774; DOI:10.1158/0008-5472.CAN-04-2293

  • Cell and Tumor Biology
    Topotecan Blocks Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Expression Induced by Insulin-Like Growth Factor-I in Neuroblastoma Cells
    Kiichiro Beppu, Katsuya Nakamura, W. Marston Linehan, Annamaria Rapisarda and Carol J. Thiele
    Cancer Res June 1 2005 65 (11) 4775-4781; DOI:10.1158/0008-5472.CAN-04-3332

  • Cell and Tumor Biology
    Inability of Transforming Growth Factor-β to Cause SnoN Degradation Leads to Resistance to Transforming Growth Factor-β–Induced Growth Arrest in Esophageal Cancer Cells
    Jeffery S. Edmiston, W. Andrew Yeudall, Theodore D. Chung and Deborah A. Lebman
    Cancer Res June 1 2005 65 (11) 4782-4788; DOI:10.1158/0008-5472.CAN-04-4354

  • Cell and Tumor Biology
    The Synthetic Triterpenoids, CDDO and CDDO-Imidazolide, Are Potent Inducers of Heme Oxygenase-1 and Nrf2/ARE Signaling
    Karen Liby, Thomas Hock, Mark M. Yore, Nanjoo Suh, Andrew E. Place, Renee Risingsong, Charlotte R. Williams, Darlene B. Royce, Tadashi Honda, Yukiko Honda, Gordon W. Gribble, Nathalie Hill-Kapturczak, Anupam Agarwal and Michael B. Sporn
    Cancer Res June 1 2005 65 (11) 4789-4798; DOI:10.1158/0008-5472.CAN-04-4539

Experimental Therapeutics, Molecular Targets, and Chemical Biology

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Synthetic Triterpenoids Cooperate with Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand to Induce Apoptosis of Breast Cancer Cells
    Marc L. Hyer, Rhonda Croxton, Maryla Krajewska, Stanislaw Krajewski, Christina L. Kress, Meiling Lu, Nanjoo Suh, Michael B. Sporn, Vincent L. Cryns, Juan M. Zapata and John C. Reed
    Cancer Res June 1 2005 65 (11) 4799-4808; DOI:10.1158/0008-5472.CAN-04-3319

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Loss of RUNX3 Expression Significantly Affects the Clinical Outcome of Gastric Cancer Patients and Its Restoration Causes Drastic Suppression of Tumor Growth and Metastasis
    Daoyan Wei, Weida Gong, Sang C. Oh, Qiang Li, Won Dong Kim, Liwei Wang, Xiangdong Le, James Yao, Tsung T. Wu, Suyun Huang and Keping Xie
    Cancer Res June 1 2005 65 (11) 4809-4816; DOI:10.1158/0008-5472.CAN-04-3741

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Hypoxia-Inducible Protein 2 (HIG2), a Novel Diagnostic Marker for Renal Cell Carcinoma and Potential Target for Molecular Therapy
    Akira Togashi, Toyomasa Katagiri, Shingo Ashida, Tomoaki Fujioka, Osamu Maruyama, Yoshiaki Wakumoto, Yoshiro Sakamoto, Makoto Fujime, Yoshio Kawachi, Taro Shuin and Yusuke Nakamura
    Cancer Res June 1 2005 65 (11) 4817-4826; DOI:10.1158/0008-5472.CAN-05-0120

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    A Novel Peptide Specifically Binding to Interleukin-6 Receptor (gp80) Inhibits Angiogenesis and Tumor Growth
    Jen-Liang Su, Kuo-Pao Lai, Chi-An Chen, Ching-Yao Yang, Pei-Sheng Chen, Chiao-Chia Chang, Chia-Hung Chou, Chi-Lun Hu, Min-Liang Kuo, Chang-Yao Hsieh and Lin-Hung Wei
    Cancer Res June 1 2005 65 (11) 4827-4835; DOI:10.1158/0008-5472.CAN-05-0188

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Hyperthermia-Induced Proteasome Inhibition and Loss of Androgen Receptor Expression in Human Prostate Cancer Cells
    Frank Pajonk, Arndt van Ophoven and William H. McBride
    Cancer Res June 1 2005 65 (11) 4836-4843; DOI:10.1158/0008-5472.CAN-03-2749

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    A Novel Polypyrimidine Antitumor Agent FdUMP[10] Induces Thymineless Death with Topoisomerase I-DNA Complexes
    Zhi-Yong Liao, Olivier Sordet, Hong-Liang Zhang, Glenda Kohlhagen, Smitha Antony, William H. Gmeiner and Yves Pommier
    Cancer Res June 1 2005 65 (11) 4844-4851; DOI:10.1158/0008-5472.CAN-04-1302

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Flavonoid Structure-Activity Studies Identify 6-Prenylchrysin and Tectochrysin as Potent and Specific Inhibitors of Breast Cancer Resistance Protein ABCG2
    Abdelhakim Ahmed-Belkacem, Alexandre Pozza, Francisco Muñoz-Martínez, Susan E. Bates, Santiago Castanys, Francisco Gamarro, Attilio Di Pietro and José M. Pérez-Victoria
    Cancer Res June 1 2005 65 (11) 4852-4860; DOI:10.1158/0008-5472.CAN-04-1817

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Akt Activation Suppresses Chk2-Mediated, Methylating Agent–Induced G2 Arrest and Protects from Temozolomide-Induced Mitotic Catastrophe and Cellular Senescence
    Yuchi Hirose, Makoto Katayama, Olga K. Mirzoeva, Mitchel S. Berger and Russell O. Pieper
    Cancer Res June 1 2005 65 (11) 4861-4869; DOI:10.1158/0008-5472.CAN-04-2633

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Pharmacologic Inhibition of RAF→MEK→ERK Signaling Elicits Pancreatic Cancer Cell Cycle Arrest Through Induced Expression of p27Kip1
    Stephan Gysin, Sang-Hyun Lee, Nicholas M. Dean and Martin McMahon
    Cancer Res June 1 2005 65 (11) 4870-4880; DOI:10.1158/0008-5472.CAN-04-2848

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Survivin as a Radioresistance Factor, and Prognostic and Therapeutic Target for Radiotherapy in Rectal Cancer
    Franz Rödel, Jörg Hoffmann, Luitpold Distel, Martin Herrmann, Timmo Noisternig, Thomas Papadopoulos, Rolf Sauer and Claus Rödel
    Cancer Res June 1 2005 65 (11) 4881-4887; DOI:10.1158/0008-5472.CAN-04-3028

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Efforts to Control the Errant Products of a Targeted In vivo Generator
    Jaspreet Singh Jaggi, Barry J. Kappel, Michael R. McDevitt, George Sgouros, Carlos D. Flombaum, Catalina Cabassa and David A. Scheinberg
    Cancer Res June 1 2005 65 (11) 4888-4895; DOI:10.1158/0008-5472.CAN-04-3096

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    8-Chloro-Cyclic AMP–Induced Growth Inhibition and Apoptosis Is Mediated by p38 Mitogen-Activated Protein Kinase Activation in HL60 Cells
    Young-Ho Ahn, Joong Mok Jung and Seung Hwan Hong
    Cancer Res June 1 2005 65 (11) 4896-4901; DOI:10.1158/0008-5472.CAN-04-3122

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Bortezomib Abolishes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Resistance via a p21-Dependent Mechanism in Human Bladder and Prostate Cancer Cells
    Laura M. Lashinger, Keyi Zhu, Simon A. Williams, Marissa Shrader, Colin P.N. Dinney and David J. McConkey
    Cancer Res June 1 2005 65 (11) 4902-4908; DOI:10.1158/0008-5472.CAN-04-3701

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Apoptosis Induction by a Novel Retinoid-Related Molecule Requires Nuclear Factor-κB Activation
    Lulu Farhana, Marcia I. Dawson and Joseph A. Fontana
    Cancer Res June 1 2005 65 (11) 4909-4917; DOI:10.1158/0008-5472.CAN-04-4124

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Identification of Novel Small Molecule Inhibitors of Hypoxia-Inducible Factor-1 That Differentially Block Hypoxia-Inducible Factor-1 Activity and Hypoxia-Inducible Factor-1α Induction in Response to Hypoxic Stress and Growth Factors
    Noan-Minh Chau, Paul Rogers, Wynne Aherne, Veronica Carroll, Ian Collins, Edward McDonald, Paul Workman and Margaret Ashcroft
    Cancer Res June 1 2005 65 (11) 4918-4928; DOI:10.1158/0008-5472.CAN-04-4453

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    The Heat Shock Protein 90 Inhibitor, 17-Allylamino-17-demethoxygeldanamycin, Enhances Osteoclast Formation and Potentiates Bone Metastasis of a Human Breast Cancer Cell Line
    John T. Price, Julian M.W. Quinn, Natalie A. Sims, Jessica Vieusseux, Kelly Waldeck, Susan E. Docherty, Damian Myers, Akira Nakamura, Mark C. Waltham, Matthew T. Gillespie and Erik W. Thompson
    Cancer Res June 1 2005 65 (11) 4929-4938; DOI:10.1158/0008-5472.CAN-04-4458

Immunology

  • Immunology
    Rationale for Antiangiogenic Cancer Therapy with Vaccination Using Epitope Peptides Derived from Human Vascular Endothelial Growth Factor Receptor 2
    Satoshi Wada, Takuya Tsunoda, Toshiyuki Baba, F. James Primus, Hiroyuki Kuwano, Masabumi Shibuya and Hideaki Tahara
    Cancer Res June 1 2005 65 (11) 4939-4946; DOI:10.1158/0008-5472.CAN-04-3759

  • Immunology
    Hsp70-Like Protein 1 Fusion Protein Enhances Induction of Carcinoembryonic Antigen–Specific CD8+ CTL Response by Dendritic Cell Vaccine
    Yanfeng Wu, Tao Wan, Xiangyang Zhou, Baomei Wang, Feng Yang, Nan Li, Guoyou Chen, Shengming Dai, Shuxun Liu, Minghui Zhang and Xuetao Cao
    Cancer Res June 1 2005 65 (11) 4947-4954; DOI:10.1158/0008-5472.CAN-04-3912

  • Immunology
    Tumor-Infiltrating Dendritic Cell Subsets of Progressive or Regressive Tumors Induce Suppressive or Protective Immune Responses
    Yongqing Liu, Xuguang Bi, Shulin Xu and Jim Xiang
    Cancer Res June 1 2005 65 (11) 4955-4962; DOI:10.1158/0008-5472.CAN-04-3957

  • Immunology
    PGP9.5 Promoter Methylation Is an Independent Prognostic Factor for Esophageal Squamous Cell Carcinoma
    Diana L. Mandelker, Keishi Yamashita, Yutaka Tokumaru, Koshi Mimori, David L. Howard, Yoichi Tanaka, Andre Lopes Carvalho, Wei-Wen Jiang, Hannah Lui Park, Myoung Sook Kim, Motonobu Osada, Masaki Mori and David Sidransky
    Cancer Res June 1 2005 65 (11) 4963-4968; DOI:10.1158/0008-5472.CAN-04-3923

Corrections

  • Corrections
    Spontaneous Human Adult Stem Cell Transformation
    Cancer Res June 1 2005 65 (11) 4969-4969; DOI:10.1158/0008-5472.CAN-65-11-CORA

  • Corrections
    Structure of the shRNA for Human STAT3 and the 3-Base Mismatch with Mouse STAT3 Sequences
    Cancer Res June 1 2005 65 (11) 4969-4969; DOI:10.1158/0008-5472.CAN-65-11-COR

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Cancer Research: 65 (11)
June 2005
Volume 65, Issue 11
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Issue Highlights

  • In vitro Activity of Bcr-Abl Inhibitors AMN107 and BMS-354825 against Clinically Relevant Imatinib-Resistant Abl Kinase Domain Mutants
  • EWS-FLI1 Fusion Protein Up-regulates Critical Genes in Neural Crest Development and Is Responsible for the Observed Phenotype of Ewing's Family of Tumors
  • The Prostaglandin E2 Receptor EP2 Is Required for Cyclooxygenase 2–Mediated Mammary Hyperplasia

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Cancer Research Online ISSN: 1538-7445
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