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Experimental Therapeutics, Molecular Targets and Chemical Biology

Gefitinib (“Iressa”, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2–Mediated Drug Resistance

Yoichi Nakamura, Mikio Oka, Hiroshi Soda, Ken Shiozawa, Megumi Yoshikawa, Akiko Itoh, Yoji Ikegami, Junji Tsurutani, Katsumi Nakatomi, Takeshi Kitazaki, Seiji Doi, Hisahiro Yoshida and Shigeru Kohno
Yoichi Nakamura
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Mikio Oka
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Hiroshi Soda
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Ken Shiozawa
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Megumi Yoshikawa
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Akiko Itoh
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Katsumi Nakatomi
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Takeshi Kitazaki
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Seiji Doi
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Hisahiro Yoshida
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DOI: 10.1158/0008-5472.CAN-03-2417 Published February 2005
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Article Information

Volume 65, Issue 4, pp. 1541-1546

DOI 
https://doi.org/10.1158/0008-5472.CAN-03-2417
PubMed 
15735043

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received August 5, 2003
  • Revision received June 7, 2004
  • Accepted December 1, 2004
  • Published first February 25, 2005.

Copyright & Usage 
©2005 American Association for Cancer Research.

Author Information

  1. Yoichi Nakamura1,
  2. Mikio Oka2,
  3. Hiroshi Soda1,
  4. Ken Shiozawa1,
  5. Megumi Yoshikawa3,
  6. Akiko Itoh3,
  7. Yoji Ikegami3,
  8. Junji Tsurutani1,
  9. Katsumi Nakatomi1,
  10. Takeshi Kitazaki1,
  11. Seiji Doi1,
  12. Hisahiro Yoshida3, and
  13. Shigeru Kohno1
  1. 1Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan; 2Division of Respiratory Medicine, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan; and 3Department of Drug Metabolism and Disposition, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan
  1. Requests for reprints:
    Mikio Oka, Division of Respiratory Medicine, Department of Internal Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701-0192, Japan. Phone: 81-86-462-1111; Fax: 81-86-464-1041; E-mail: moom{at}med.kawasaki-m.ac.jp.
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Cancer Research: 65 (4)
February 2005
Volume 65, Issue 4
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Gefitinib (“Iressa”, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2–Mediated Drug Resistance
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Gefitinib (“Iressa”, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2–Mediated Drug Resistance
Yoichi Nakamura, Mikio Oka, Hiroshi Soda, Ken Shiozawa, Megumi Yoshikawa, Akiko Itoh, Yoji Ikegami, Junji Tsurutani, Katsumi Nakatomi, Takeshi Kitazaki, Seiji Doi, Hisahiro Yoshida and Shigeru Kohno
Cancer Res February 15 2005 (65) (4) 1541-1546; DOI: 10.1158/0008-5472.CAN-03-2417

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Gefitinib (“Iressa”, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses Breast Cancer Resistance Protein/ABCG2–Mediated Drug Resistance
Yoichi Nakamura, Mikio Oka, Hiroshi Soda, Ken Shiozawa, Megumi Yoshikawa, Akiko Itoh, Yoji Ikegami, Junji Tsurutani, Katsumi Nakatomi, Takeshi Kitazaki, Seiji Doi, Hisahiro Yoshida and Shigeru Kohno
Cancer Res February 15 2005 (65) (4) 1541-1546; DOI: 10.1158/0008-5472.CAN-03-2417
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Cancer Research Online ISSN: 1538-7445
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