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Experimental Therapeutics, Molecular Targets, and Chemical Biology

A Chemical Screen Identifies Anisomycin as an Anoikis Sensitizer That Functions by Decreasing FLIP Protein Synthesis

Imtiaz A. Mawji, Craig D. Simpson, Marcela Gronda, Moyo A. Williams, Rose Hurren, Clare J. Henderson, Alessandro Datti, Jeffrey L. Wrana and Aaron D. Schimmer
Imtiaz A. Mawji
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Craig D. Simpson
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Marcela Gronda
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Moyo A. Williams
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Rose Hurren
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Clare J. Henderson
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Alessandro Datti
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Jeffrey L. Wrana
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Aaron D. Schimmer
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DOI: 10.1158/0008-5472.CAN-07-1687 Published September 2007
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Article Information

Volume 67, Issue 17, pp. 8307-8315

DOI 
https://doi.org/10.1158/0008-5472.CAN-07-1687
PubMed 
17804746

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received May 8, 2007
  • Revision received June 4, 2007
  • Accepted June 26, 2007
  • Published first September 5, 2007.

Copyright & Usage 
©2007 American Association for Cancer Research.

Author Information

  1. Imtiaz A. Mawji1,
  2. Craig D. Simpson1,
  3. Marcela Gronda1,
  4. Moyo A. Williams1,
  5. Rose Hurren1,
  6. Clare J. Henderson1,
  7. Alessandro Datti2,
  8. Jeffrey L. Wrana2, and
  9. Aaron D. Schimmer1
  1. 1Ontario Cancer Institute, Princess Margaret Hospital and 2Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada
  1. Requests for reprints:
    Aaron D. Schimmer, Ontario Cancer Institute, Princess Margaret Hospital, 610 University Avenue Toronto, ON, Canada M5G 2M9. Phone: 416-946-2838; E-mail: aaron.schimmer{at}utoronto.ca.
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Cancer Research: 67 (17)
September 2007
Volume 67, Issue 17
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A Chemical Screen Identifies Anisomycin as an Anoikis Sensitizer That Functions by Decreasing FLIP Protein Synthesis
Imtiaz A. Mawji, Craig D. Simpson, Marcela Gronda, Moyo A. Williams, Rose Hurren, Clare J. Henderson, Alessandro Datti, Jeffrey L. Wrana and Aaron D. Schimmer
Cancer Res September 1 2007 (67) (17) 8307-8315; DOI: 10.1158/0008-5472.CAN-07-1687

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A Chemical Screen Identifies Anisomycin as an Anoikis Sensitizer That Functions by Decreasing FLIP Protein Synthesis
Imtiaz A. Mawji, Craig D. Simpson, Marcela Gronda, Moyo A. Williams, Rose Hurren, Clare J. Henderson, Alessandro Datti, Jeffrey L. Wrana and Aaron D. Schimmer
Cancer Res September 1 2007 (67) (17) 8307-8315; DOI: 10.1158/0008-5472.CAN-07-1687
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