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Table of Contents

Commentary

  • Commentary
    Genetic Variation at 8q24 as a Susceptibility Factor for Prostate Cancer: Definitive Results from Epidemiologic Studies?
    Elizabeth A. Platz
    Cancer Res April 1 2007 67 (7) 2905-2907; DOI:10.1158/0008-5472.CAN-07-0737

Reviews

  • Reviews
    Targeting Multiple Arms of the Apoptotic Regulatory Machinery
    Yun Dai and Steven Grant
    Cancer Res April 1 2007 67 (7) 2908-2911; DOI:10.1158/0008-5472.CAN-07-0082

  • Reviews
    Tumor-Released Microvesicles as Vehicles of Immunosuppression
    Roberta Valenti, Veronica Huber, Manuela Iero, Paola Filipazzi, Giorgio Parmiani and Licia Rivoltini
    Cancer Res April 1 2007 67 (7) 2912-2915; DOI:10.1158/0008-5472.CAN-07-0520

Priority Reports

  • Priority Reports
    Dual Role of Inactivating Lef1 Mutations in Epidermis: Tumor Promotion and Specification of Tumor Type
    Catherin Niemann, David M. Owens, Peter Schettina and Fiona M. Watt
    Cancer Res April 1 2007 67 (7) 2916-2921; DOI:10.1158/0008-5472.CAN-06-3427

  • Priority Reports
    PRL-3 Down-regulates PTEN Expression and Signals through PI3K to Promote Epithelial-Mesenchymal Transition
    Haihe Wang, Samantha Yiling Quah, Jing Ming Dong, Edward Manser, Jing Ping Tang and Qi Zeng
    Cancer Res April 1 2007 67 (7) 2922-2926; DOI:10.1158/0008-5472.CAN-06-3598

  • Priority Reports
    Mammalian Tumor Xenografts Induce Neovascularization in Zebrafish Embryos
    Stefania Nicoli, Domenico Ribatti, Franco Cotelli and Marco Presta
    Cancer Res April 1 2007 67 (7) 2927-2931; DOI:10.1158/0008-5472.CAN-06-4268

  • Priority Reports
    High HSP90 Expression Is Associated with Decreased Survival in Breast Cancer
    Elah Pick, Yuval Kluger, Jennifer M. Giltnane, Christopher Moeder, Robert L. Camp, David L. Rimm and Harriet M. Kluger
    Cancer Res April 1 2007 67 (7) 2932-2937; DOI:10.1158/0008-5472.CAN-06-4511

  • Priority Reports
    Materializing the Potential of Small Interfering RNA via a Tumor-Targeting Nanodelivery System
    Kathleen F. Pirollo, Antonina Rait, Qi Zhou, Sung Hee Hwang, John A. Dagata, Gerald Zon, Richard I. Hogrefe, Guillermo Palchik and Esther H. Chang
    Cancer Res April 1 2007 67 (7) 2938-2943; DOI:10.1158/0008-5472.CAN-06-4535

  • Priority Reports
    Two Common Chromosome 8q24 Variants Are Associated with Increased Risk for Prostate Cancer
    Liang Wang, Shannon K. McDonnell, Joshua P. Slusser, Scott J. Hebbring, Julie M. Cunningham, Steven J. Jacobsen, James R. Cerhan, Michael L. Blute, Daniel J. Schaid and Stephen N. Thibodeau
    Cancer Res April 1 2007 67 (7) 2944-2950; DOI:10.1158/0008-5472.CAN-06-3186

  • Priority Reports
    A Common 8q24 Variant in Prostate and Breast Cancer from a Large Nested Case-Control Study
    Fredrick R. Schumacher, Heather Spencer Feigelson, David G. Cox, Christopher A. Haiman, Demetrius Albanes, Julie Buring, Eugenia E. Calle, Stephen J. Chanock, Graham A. Colditz, W. Ryan Diver, Alison M. Dunning, Matthew L. Freedman, John M. Gaziano, Edward Giovannucci, Sue E. Hankinson, Richard B. Hayes, Brian E. Henderson, Robert N. Hoover, Rudolf Kaaks, Timothy Key, Laurence N. Kolonel, Peter Kraft, Loic Le Marchand, Jing Ma, Malcolm C. Pike, Elio Riboli, Meir J. Stampfer, Daniel O. Stram, Gilles Thomas, Michael J. Thun, Ruth Travis, Jarmo Virtamo, Gerald Andriole, Edward Gelmann, Walter C. Willett and David J. Hunter
    Cancer Res April 1 2007 67 (7) 2951-2956; DOI:10.1158/0008-5472.CAN-06-3591

Molecular Biology, Pathobiology, and Genetics

  • Molecular Biology, Pathobiology, and Genetics
    Aurora A and B Overexpression and Centrosome Amplification in Early Estrogen-Induced Tumor Foci in the Syrian Hamster Kidney: Implications for Chromosomal Instability, Aneuploidy, and Neoplasia
    Adrianne E. Hontz, Sara Antonia Li, Wilma L. Lingle, Vivian Negron, Amy Bruzek, Jeffrey L. Salisbury and Jonathan J. Li
    Cancer Res April 1 2007 67 (7) 2957-2963; DOI:10.1158/0008-5472.CAN-06-3296

  • Molecular Biology, Pathobiology, and Genetics
    Fatty Acid Synthase Inhibition Activates AMP-Activated Protein Kinase in SKOV3 Human Ovarian Cancer Cells
    Weibo Zhou, Wan Fang Han, Leslie E. Landree, Jagan N. Thupari, Michael L. Pinn, Tsion Bililign, Eun Kyoung Kim, Aravinda Vadlamudi, Susan M. Medghalchi, Rajaa El Meskini, Gabriele V. Ronnett, Craig A. Townsend and Francis P. Kuhajda
    Cancer Res April 1 2007 67 (7) 2964-2971; DOI:10.1158/0008-5472.CAN-06-3439

  • Molecular Biology, Pathobiology, and Genetics
    Tumor Suppression by IFN Regulatory Factor-1 Is Mediated by Transcriptional Down-regulation of Cyclin D1
    Andrea Kröger, Anja Stirnweiss, Julia Elisabeth Pulverer, Katjana Klages, Martina Grashoff, Jörg Reimann and Hansjörg Hauser
    Cancer Res April 1 2007 67 (7) 2972-2981; DOI:10.1158/0008-5472.CAN-06-3564

  • Molecular Biology, Pathobiology, and Genetics
    Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling
    Wee J. Chng, Shaji Kumar, Scott VanWier, Greg Ahmann, Tammy Price-Troska, Kim Henderson, Tae-Hoon Chung, Seungchan Kim, George Mulligan, Barbara Bryant, John Carpten, Morie Gertz, S. Vincent Rajkumar, Martha Lacy, Angela Dispenzieri, Robert Kyle, Philip Greipp, P. Leif Bergsagel and Rafael Fonseca
    Cancer Res April 1 2007 67 (7) 2982-2989; DOI:10.1158/0008-5472.CAN-06-4046

  • Molecular Biology, Pathobiology, and Genetics
    Isogenic Normal Basal and Luminal Mammary Epithelial Isolated by a Novel Method Show a Differential Response to Ionizing Radiation
    Gudrun Huper and Jeffrey R. Marks
    Cancer Res April 1 2007 67 (7) 2990-3001; DOI:10.1158/0008-5472.CAN-06-4065

  • Molecular Biology, Pathobiology, and Genetics
    Tumor-Specific Cooperation of Retinoblastoma Protein Family and Snf5 Inactivation
    Jingjing Chai, Xiangdong Lu, Virginia Godfrey, Christopher Fletcher, Charles W.M. Roberts, Terry Van Dyke and Bernard E. Weissman
    Cancer Res April 1 2007 67 (7) 3002-3009; DOI:10.1158/0008-5472.CAN-06-4207

  • Molecular Biology, Pathobiology, and Genetics
    Hyperthermia Activates a Subset of Ataxia-Telangiectasia Mutated Effectors Independent of DNA Strand Breaks and Heat Shock Protein 70 Status
    Clayton R. Hunt, Raj K. Pandita, Andrei Laszlo, Ryuji Higashikubo, Manjula Agarwal, Tetsuya Kitamura, Arun Gupta, Nicole Rief, Nobuo Horikoshi, Rajeskaran Baskaran, Ji-Hoon Lee, Markus Löbrich, Tanya T. Paull, Joseph L. Roti Roti and Tej K. Pandita
    Cancer Res April 1 2007 67 (7) 3010-3017; DOI:10.1158/0008-5472.CAN-06-4328

  • Molecular Biology, Pathobiology, and Genetics
    Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase η, DNA Polymerase ι Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations
    Yun Wang, Roger Woodgate, Terrence P. McManus, Samantha Mead, J. Justin McCormick and Veronica M. Maher
    Cancer Res April 1 2007 67 (7) 3018-3026; DOI:10.1158/0008-5472.CAN-06-3073

  • Molecular Biology, Pathobiology, and Genetics
    Tagging Single Nucleotide Polymorphisms in Cell Cycle Control Genes and Susceptibility to Invasive Epithelial Ovarian Cancer
    Simon A. Gayther, Honglin Song, Susan J. Ramus, Susan Krüger Kjaer, Alice S. Whittemore, Lydia Quaye, Jonathan Tyrer, Danielle Shadforth, Estrid Hogdall, Claus Hogdall, Jan Blaeker, Richard DiCioccio, Valerie McGuire, Penelope M. Webb, Jonathan Beesley, Adele C. Green, David C. Whiteman, The Australian Ovarian Cancer Study Group, The Australian Cancer Study (Ovarian Cancer), Marc T. Goodman, Galina Lurie, Michael E. Carney, Francesmary Modugno, Roberta B. Ness, Robert P. Edwards, Kirsten B. Moysich, Ellen L. Goode, Fergus J. Couch, Julie M. Cunningham, Thomas A. Sellers, Anna H. Wu, Malcolm C. Pike, Edwin S. Iversen, Jeffrey R. Marks, Montserrat Garcia-Closas, Louise Brinton, Jolanta Lissowska, Beata Peplonska, Douglas F. Easton, Ian Jacobs, Bruce A.J. Ponder, Joellen Schildkraut, C. Leigh Pearce, Georgia Chenevix-Trench, Andrew Berchuck, Paul D.P. Pharoah and ; on behalf of the Ovarian Cancer Association Consortium
    Cancer Res April 1 2007 67 (7) 3027-3035; DOI:10.1158/0008-5472.CAN-06-3261

  • Molecular Biology, Pathobiology, and Genetics
    Six1 Overexpression in Ovarian Carcinoma Causes Resistance to TRAIL-Mediated Apoptosis and Is Associated with Poor Survival
    Kian Behbakht, Lubna Qamar, Carrie S. Aldridge, Ricardo D. Coletta, Susan A. Davidson, Andrew Thorburn and Heide L. Ford
    Cancer Res April 1 2007 67 (7) 3036-3042; DOI:10.1158/0008-5472.CAN-06-3755

  • Molecular Biology, Pathobiology, and Genetics
    The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways
    Zhaohui Feng, Wenwei Hu, Elisa de Stanchina, Angelika K. Teresky, Shengkan Jin, Scott Lowe and Arnold J. Levine
    Cancer Res April 1 2007 67 (7) 3043-3053; DOI:10.1158/0008-5472.CAN-06-4149

Cell, Tumor, and Stem Cell Biology

  • Cell, Tumor, and Stem Cell Biology
    Effect of Human Skin-Derived Stem Cells on Vessel Architecture, Tumor Growth, and Tumor Invasion in Brain Tumor Animal Models
    Federica Pisati, Marzia Belicchi, Francesco Acerbi, Chiara Marchesi, Carlo Giussani, Manuela Gavina, Sophie Javerzat, Martin Hagedorn, Giorgio Carrabba, Valeria Lucini, Sergio Maria Gaini, Nereo Bresolin, Lorenzo Bello, Andreas Bikfalvi and Yvan Torrente
    Cancer Res April 1 2007 67 (7) 3054-3063; DOI:10.1158/0008-5472.CAN-06-1384

  • Cell, Tumor, and Stem Cell Biology
    RaLP, a New Member of the Src Homology and Collagen Family, Regulates Cell Migration and Tumor Growth of Metastatic Melanomas
    Ernesta Fagiani, Giuseppina Giardina, Lucilla Luzi, Matteo Cesaroni, Micaela Quarto, Maria Capra, Giovanni Germano, Maria Bono, Manuela Capillo, PierGiuseppe Pelicci and Luisa Lanfrancone
    Cancer Res April 1 2007 67 (7) 3064-3073; DOI:10.1158/0008-5472.CAN-06-2301

  • Cell, Tumor, and Stem Cell Biology
    Amplification of MDS1/EVI1 and EVI1, Located in the 3q26.2 Amplicon, Is Associated with Favorable Patient Prognosis in Ovarian Cancer
    Meera Nanjundan, Yasuhisa Nakayama, Kwai Wa Cheng, John Lahad, Jinsong Liu, Karen Lu, Wen-Lin Kuo, Karen Smith-McCune, David Fishman, Joe W. Gray and Gordon B. Mills
    Cancer Res April 1 2007 67 (7) 3074-3084; DOI:10.1158/0008-5472.CAN-06-2366

  • Cell, Tumor, and Stem Cell Biology
    Construction and Validation of Improved Triple Fusion Reporter Gene Vectors for Molecular Imaging of Living Subjects
    Pritha Ray, Roger Tsien and Sanjiv Sam Gambhir
    Cancer Res April 1 2007 67 (7) 3085-3093; DOI:10.1158/0008-5472.CAN-06-2402

  • Cell, Tumor, and Stem Cell Biology
    E-Cadherin Cell-Cell Adhesion in Ewing Tumor Cells Mediates Suppression of Anoikis through Activation of the ErbB4 Tyrosine Kinase
    Hyung-Gyoo Kang, Jasmine M. Jenabi, Jingsong Zhang, Nino Keshelava, Hiroyuki Shimada, William A. May, Tony Ng, C. Patrick Reynolds, Timothy J. Triche and Poul H.B. Sorensen
    Cancer Res April 1 2007 67 (7) 3094-3105; DOI:10.1158/0008-5472.CAN-06-3259

  • Cell, Tumor, and Stem Cell Biology
    N-Cadherin Signaling Potentiates Mammary Tumor Metastasis via Enhanced Extracellular Signal-Regulated Kinase Activation
    James Hulit, Kimita Suyama, Su Chung, Rinat Keren, Georgia Agiostratidou, Weisong Shan, Xinyuan Dong, Terence M. Williams, Michael P. Lisanti, Karen Knudsen and Rachel B. Hazan
    Cancer Res April 1 2007 67 (7) 3106-3116; DOI:10.1158/0008-5472.CAN-06-3401

  • Cell, Tumor, and Stem Cell Biology
    Senescent Human Fibroblasts Increase the Early Growth of Xenograft Tumors via Matrix Metalloproteinase Secretion
    Dan Liu and Peter J. Hornsby
    Cancer Res April 1 2007 67 (7) 3117-3126; DOI:10.1158/0008-5472.CAN-06-3452

  • Cell, Tumor, and Stem Cell Biology
    Systemic Targeting Inhibitor of κB Kinase Inhibits Melanoma Tumor Growth
    Jinming Yang, Wei-Hua Pan, Gary A. Clawson and Ann Richmond
    Cancer Res April 1 2007 67 (7) 3127-3134; DOI:10.1158/0008-5472.CAN-06-3547

  • Cell, Tumor, and Stem Cell Biology
    Tumors Initiated by Constitutive Cdk2 Activation Exhibit Transforming Growth Factor β Resistance and Acquire Paracrine Mitogenic Stimulation during Progression
    Patrick Corsino, Bradley Davis, Mary Law, Anna Chytil, Elizabeth Forrester, Peter Nørgaard, Nicole Teoh and Brian Law
    Cancer Res April 1 2007 67 (7) 3135-3144; DOI:10.1158/0008-5472.CAN-06-3815

  • Cell, Tumor, and Stem Cell Biology
    Histone Deacetylase 2 Modulates p53 Transcriptional Activities through Regulation of p53-DNA Binding Activity
    Kelly Lynn Harms and Xinbin Chen
    Cancer Res April 1 2007 67 (7) 3145-3152; DOI:10.1158/0008-5472.CAN-06-4397

  • Cell, Tumor, and Stem Cell Biology
    Identification of Putative Stem Cell Markers, CD133 and CXCR4, in hTERT–Immortalized Primary Nonmalignant and Malignant Tumor-Derived Human Prostate Epithelial Cell Lines and in Prostate Cancer Specimens
    Jun Miki, Bungo Furusato, Hongzhen Li, Yongpeng Gu, Hiroyuki Takahashi, Shin Egawa, Isabell A. Sesterhenn, David G. McLeod, Shiv Srivastava and Johng S. Rhim
    Cancer Res April 1 2007 67 (7) 3153-3161; DOI:10.1158/0008-5472.CAN-06-4429

  • Cell, Tumor, and Stem Cell Biology
    p18Ink4c Collaborates with Men1 to Constrain Lung Stem Cell Expansion and Suppress Non–Small-Cell Lung Cancers
    Xin-Hai Pei, Feng Bai, Matthew D. Smith and Yue Xiong
    Cancer Res April 1 2007 67 (7) 3162-3170; DOI:10.1158/0008-5472.CAN-06-4517

  • Cell, Tumor, and Stem Cell Biology
    Detection of DNA Copy Number Changes and Oncogenic Signaling Abnormalities from Gene Expression Data Reveals MYC Activation in High-Grade Papillary Renal Cell Carcinoma
    Kyle A. Furge, Jindong Chen, Julie Koeman, Pamela Swiatek, Karl Dykema, Kseniji Lucin, Richard Kahnoski, Ximing J. Yang and Bin Tean Teh
    Cancer Res April 1 2007 67 (7) 3171-3176; DOI:10.1158/0008-5472.CAN-06-4571

  • Cell, Tumor, and Stem Cell Biology
    Mutant V600E BRAF Increases Hypoxia Inducible Factor-1α Expression in Melanoma
    Suresh M. Kumar, Hong Yu, Robin Edwards, Lianjun Chen, Steven Kazianis, Patricia Brafford, Geza Acs, Meenhard Herlyn and Xiaowei Xu
    Cancer Res April 1 2007 67 (7) 3177-3184; DOI:10.1158/0008-5472.CAN-06-3312

  • Cell, Tumor, and Stem Cell Biology
    Nonsteroidal Anti-inflammatory Drugs Induce Colorectal Cancer Cell Apoptosis by Suppressing 14-3-3ε
    Jun-Yang Liou, Dipak Ghelani, Sam Yeh and Kenneth K. Wu
    Cancer Res April 1 2007 67 (7) 3185-3191; DOI:10.1158/0008-5472.CAN-06-3431

  • Cell, Tumor, and Stem Cell Biology
    Cellular Transformation and Activation of the Phosphoinositide-3-Kinase–Akt Cascade by the ETV6-NTRK3 Chimeric Tyrosine Kinase Requires c-Src
    Wook Jin, Chohee Yun, Amy Hobbie, Matthew J. Martin, Poul H.B. Sorensen and Seong-Jin Kim
    Cancer Res April 1 2007 67 (7) 3192-3200; DOI:10.1158/0008-5472.CAN-06-3526

Experimental Therapeutics, Molecular Targets, and Chemical Biology

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Salmonella typhimurium Lacking Ribose Chemoreceptors Localize in Tumor Quiescence and Induce Apoptosis
    Rachel W. Kasinskas and Neil S. Forbes
    Cancer Res April 1 2007 67 (7) 3201-3209; DOI:10.1158/0008-5472.CAN-06-2618

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Mitogen-Activated Protein Kinase Kinase Inhibition Enhances Nuclear Proapoptotic Function of p53 in Acute Myelogenous Leukemia Cells
    Kensuke Kojima, Marina Konopleva, Ismael J. Samudio, Vivian Ruvolo and Michael Andreeff
    Cancer Res April 1 2007 67 (7) 3210-3219; DOI:10.1158/0008-5472.CAN-06-2712

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Nuclear Factor-κB and Manganese Superoxide Dismutase Mediate Adaptive Radioresistance in Low-Dose Irradiated Mouse Skin Epithelial Cells
    Ming Fan, Kazi Mokim Ahmed, Mitchell C. Coleman, Douglas R. Spitz and Jian Jian Li
    Cancer Res April 1 2007 67 (7) 3220-3228; DOI:10.1158/0008-5472.CAN-06-2728

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Peroxisome Proliferator-Activated Receptor γ–Independent Suppression of Androgen Receptor Expression by Troglitazone Mechanism and Pharmacologic Exploitation
    Chih-Cheng Yang, Yu-Chieh Wang, Shuo Wei, Li-Fang Lin, Chang-Shi Chen, Cheng-Chun Lee, Cheng-Chieh Lin and Ching-Shih Chen
    Cancer Res April 1 2007 67 (7) 3229-3238; DOI:10.1158/0008-5472.CAN-06-2759

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin
    Alison Maloney, Paul A. Clarke, Soren Naaby-Hansen, Rob Stein, Jens-Oliver Koopman, Akunna Akpan, Alice Yang, Marketa Zvelebil, Rainer Cramer, Lindsay Stimson, Wynne Aherne, Udai Banerji, Ian Judson, Swee Sharp, Marissa Powers, Emmanuel deBilly, Joanne Salmons, Michael Walton, Al Burlingame, Michael Waterfield and Paul Workman
    Cancer Res April 1 2007 67 (7) 3239-3253; DOI:10.1158/0008-5472.CAN-06-2968

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    The Aryl Propionic Acid R-Flurbiprofen Selectively Induces p75NTR-Dependent Decreased Survival of Prostate Tumor Cells
    Emily J. Quann, Fatima Khwaja, Kenton H. Zavitz and Daniel Djakiew
    Cancer Res April 1 2007 67 (7) 3254-3262; DOI:10.1158/0008-5472.CAN-06-3657

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Isoleucine, an Essential Amino Acid, Prevents Liver Metastases of Colon Cancer by Antiangiogenesis
    Kazumoto Murata and Masami Moriyama
    Cancer Res April 1 2007 67 (7) 3263-3268; DOI:10.1158/0008-5472.CAN-06-3739

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    IFN-γ Enhances the Antimyeloma Activity of the Fully Human Anti–Human Leukocyte Antigen-DR Monoclonal Antibody 1D09C3
    Carmelo Carlo-Stella, Anna Guidetti, Massimo Di Nicola, Cristiana Lavazza, Loredana Cleris, Daniela Sia, Paolo Longoni, Marco Milanesi, Michele Magni, Zoltan Nagy, Paolo Corradini, Antonino Carbone, Franca Formelli and Alessandro M. Gianni
    Cancer Res April 1 2007 67 (7) 3269-3275; DOI:10.1158/0008-5472.CAN-06-3744

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Oncogenic Role of MPHOSPH1, a Cancer-Testis Antigen Specific to Human Bladder Cancer
    Mitsugu Kanehira, Toyomasa Katagiri, Arata Shimo, Ryo Takata, Taro Shuin, Tsuneharu Miki, Tomoaki Fujioka and Yusuke Nakamura
    Cancer Res April 1 2007 67 (7) 3276-3285; DOI:10.1158/0008-5472.CAN-06-3748

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Regulation of Vascular Endothelial Growth Factor Receptor-1 Expression by Specificity Proteins 1, 3, and 4 in Pancreatic Cancer Cells
    Maen Abdelrahim, Cheryl H. Baker, James L. Abbruzzese, David Sheikh-Hamad, Shengxi Liu, Sung Dae Cho, Kyungsil Yoon and Stephen Safe
    Cancer Res April 1 2007 67 (7) 3286-3294; DOI:10.1158/0008-5472.CAN-06-3831

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Positron Emission Tomography of Herpes Simplex Virus 1 Oncolysis
    Darshini Kuruppu, Anna-Liisa Brownell, Aijun Zhu, Meixiang Yu, Xukui Wang, Yakup Kulu, Bryan C. Fuchs, Hiroshi Kawasaki and Kenneth K. Tanabe
    Cancer Res April 1 2007 67 (7) 3295-3300; DOI:10.1158/0008-5472.CAN-06-4062

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Repression of IFN Regulatory Factor 8 by DNA Methylation Is a Molecular Determinant of Apoptotic Resistance and Metastatic Phenotype in Metastatic Tumor Cells
    Dafeng Yang, Muthusamy Thangaraju, Kristy Greeneltch, Darren D. Browning, Patricia V. Schoenlein, Tomohiko Tamura, Keiko Ozato, Vadivel Ganapathy, Scott I. Abrams and Kebin Liu
    Cancer Res April 1 2007 67 (7) 3301-3309; DOI:10.1158/0008-5472.CAN-06-4068

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Inhibition of Angiogenesis and Invasion by 3,3′-Diindolylmethane Is Mediated by the Nuclear Factor–κB Downstream Target Genes MMP-9 and uPA that Regulated Bioavailability of Vascular Endothelial Growth Factor in Prostate Cancer
    Dejuan Kong, Yiwei Li, Zhiwei Wang, Sanjeev Banerjee and Fazlul H. Sarkar
    Cancer Res April 1 2007 67 (7) 3310-3319; DOI:10.1158/0008-5472.CAN-06-4277

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Gene Expression Signature of Human Cancer Cell Lines Treated with the Ras Inhibitor Salirasib (S-Farnesylthiosalicylic Acid)
    Roy Blum, Ran Elkon, Shira Yaari, Adi Zundelevich, Jasmine Jacob-Hirsch, Gideon Rechavi, Ron Shamir and Yoel Kloog
    Cancer Res April 1 2007 67 (7) 3320-3328; DOI:10.1158/0008-5472.CAN-06-4287

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Systematic Urokinase-Activated Anthrax Toxin Therapy Produces Regressions of Subcutaneous Human Non–Small Cell Lung Tumor in Athymic Nude Mice
    Yunpeng Su, Janelle Ortiz, Shihui Liu, Thomas H. Bugge, Ravibhushan Singh, Stephen H. Leppla and Arthur E. Frankel
    Cancer Res April 1 2007 67 (7) 3329-3336; DOI:10.1158/0008-5472.CAN-06-4642

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    A Peptide Conjugate of Vitamin E Succinate Targets Breast Cancer Cells with High ErbB2 Expression
    Xiu-Fang Wang, Marc Birringer, Lan-Feng Dong, Pavel Veprek, Pauline Low, Emma Swettenham, Marina Stantic, Lin-Hong Yuan, Renata Zobalova, Kun Wu, Miroslav Ledvina, Stephen J. Ralph and Jiri Neuzil
    Cancer Res April 1 2007 67 (7) 3337-3344; DOI:10.1158/0008-5472.CAN-06-2480

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Enhanced Expression of Asparagine Synthetase under Glucose-Deprived Conditions Protects Pancreatic Cancer Cells from Apoptosis Induced by Glucose Deprivation and Cisplatin
    Hongyan Cui, Stephanie Darmanin, Mitsuteru Natsuisaka, Takeshi Kondo, Masahiro Asaka, Masanobu Shindoh, Fumihiro Higashino, Junji Hamuro, Futoshi Okada, Masataka Kobayashi, Koji Nakagawa, Hideyuki Koide and Masanobu Kobayashi
    Cancer Res April 1 2007 67 (7) 3345-3355; DOI:10.1158/0008-5472.CAN-06-2519

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Induction of Cdc25B Regulates Cell Cycle Resumption after Genotoxic Stress
    Pallavi Bansal and John S. Lazo
    Cancer Res April 1 2007 67 (7) 3356-3363; DOI:10.1158/0008-5472.CAN-06-3685

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    2-Deoxy-d-Glucose Combined with Cisplatin Enhances Cytotoxicity via Metabolic Oxidative Stress in Human Head and Neck Cancer Cells
    Andrean L. Simons, Iman M. Ahmad, David M. Mattson, Kenneth J. Dornfeld and Douglas R. Spitz
    Cancer Res April 1 2007 67 (7) 3364-3370; DOI:10.1158/0008-5472.CAN-06-3717

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Parthenolide Inhibits Tubulin Carboxypeptidase Activity
    Xavier Fonrose, Frédéric Ausseil, Emmanuelle Soleilhac, Véronique Masson, Bruno David, Isabelle Pouny, Jean-Christophe Cintrat, Bernard Rousseau, Caroline Barette, Georges Massiot and Laurence Lafanechère
    Cancer Res April 1 2007 67 (7) 3371-3378; DOI:10.1158/0008-5472.CAN-06-3732

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Cholesterol Starvation Induces Differentiation of Human Leukemia HL-60 Cells
    Carolina C. Sánchez-Martín, Alberto Dávalos, Covadonga Martín-Sánchez, Gema de la Peña, Carlos Fernández-Hernando and Miguel A. Lasunción
    Cancer Res April 1 2007 67 (7) 3379-3386; DOI:10.1158/0008-5472.CAN-06-4093

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Improvement of Antitumor Activity by Gene Amplification with a Replicating but Nondisseminating Adenovirus
    Denis Bourbeau, Cara Jean Lau, Jairo Jaime, Zafiro Koty, Simone P. Zehntner, Geneviève Lavoie, Anne-Marie Mes-Masson, Josephine Nalbantoglu and Bernard Massie
    Cancer Res April 1 2007 67 (7) 3387-3395; DOI:10.1158/0008-5472.CAN-06-4317

Immunology

  • Immunology
    CXCL10 Promotes Invasion-Related Properties in Human Colorectal Carcinoma Cells
    Adi Zipin-Roitman, Tsipi Meshel, Orit Sagi-Assif, Bruria Shalmon, Camila Avivi, Raphael M. Pfeffer, Isaac P. Witz and Adit Ben-Baruch
    Cancer Res April 1 2007 67 (7) 3396-3405; DOI:10.1158/0008-5472.CAN-06-3087

  • Immunology
    Active Induction of Tumor-Specific IgE Antibodies by Oral Mimotope Vaccination
    Angelika B. Riemer, Eva Untersmayr, Regina Knittelfelder, Albert Duschl, Hubert Pehamberger, Christoph C. Zielinski, Otto Scheiner and Erika Jensen-Jarolim
    Cancer Res April 1 2007 67 (7) 3406-3411; DOI:10.1158/0008-5472.CAN-06-3758

Endocrinology

  • Endocrinology
    Evidences that Leptin Up-regulates E-Cadherin Expression in Breast Cancer: Effects on Tumor Growth and Progression
    Loredana Mauro, Stefania Catalano, Gianluca Bossi, Michele Pellegrino, Ines Barone, Sara Morales, Cinzia Giordano, Viviana Bartella, Ivan Casaburi and Sebastiano Andò
    Cancer Res April 1 2007 67 (7) 3412-3421; DOI:10.1158/0008-5472.CAN-06-2890

  • Endocrinology
    Androgen Deprivation Increases p300 Expression in Prostate Cancer Cells
    Hannelore V. Heemers, Thomas J. Sebo, Jose D. Debes, Kevin M. Regan, Kristin A. Raclaw, Linda M. Murphy, Alfred Hobisch, Zoran Culig and Donald J. Tindall
    Cancer Res April 1 2007 67 (7) 3422-3430; DOI:10.1158/0008-5472.CAN-06-2836

Clinical Research

  • Clinical Research
    Phosphoprotein Pathway Mapping: Akt/Mammalian Target of Rapamycin Activation Is Negatively Associated with Childhood Rhabdomyosarcoma Survival
    Emanuel F. Petricoin III, Virginia Espina, Robyn P. Araujo, Brieanne Midura, Choh Yeung, Xiaolin Wan, Gabriel S. Eichler, Donald J. Johann Jr., Stephen Qualman, Maria Tsokos, Kartik Krishnan, Lee J. Helman and Lance A. Liotta
    Cancer Res April 1 2007 67 (7) 3431-3440; DOI:10.1158/0008-5472.CAN-06-1344

  • Clinical Research
    Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers
    Stuart C. Winter, Francesca M. Buffa, Priyamal Silva, Crispin Miller, Helen R. Valentine, Helen Turley, Ketan A. Shah, Graham J. Cox, Rogan J. Corbridge, Jarrod J. Homer, Brian Musgrove, Nick Slevin, Philip Sloan, Pat Price, Catharine M.L. West and Adrian L. Harris
    Cancer Res April 1 2007 67 (7) 3441-3449; DOI:10.1158/0008-5472.CAN-06-3322

  • Clinical Research
    A High-Throughput Study in Melanoma Identifies Epithelial-Mesenchymal Transition as a Major Determinant of Metastasis
    Soledad R. Alonso, Lorraine Tracey, Pablo Ortiz, Beatriz Pérez-Gómez, José Palacios, Marina Pollán, Juan Linares, Salvio Serrano, Ana I. Sáez-Castillo, Lydia Sánchez, Raquel Pajares, Abel Sánchez-Aguilera, Maria J. Artiga, Miguel A. Piris and José L. Rodríguez-Peralto
    Cancer Res April 1 2007 67 (7) 3450-3460; DOI:10.1158/0008-5472.CAN-06-3481

  • Clinical Research
    Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma
    Guoan Chen, Xiaoju Wang, Jianjun Yu, Sooryanarayana Varambally, Jindan Yu, Dafydd G. Thomas, Mu-Yen Lin, Prakash Vishnu, Zhuwen Wang, Rui Wang, Jeff Fielhauer, Debashis Ghosh, Thomas J. Giordano, Donald Giacherio, Andrew C. Chang, Mark B. Orringer, Talal El-Hefnawy, William L. Bigbee, David G. Beer and Arul M. Chinnaiyan
    Cancer Res April 1 2007 67 (7) 3461-3467; DOI:10.1158/0008-5472.CAN-06-4475

Epidemiology and Prevention

  • Epidemiology and Prevention
    Gender Differences in UVB-Induced Skin Carcinogenesis, Inflammation, and DNA Damage
    Jennifer M. Thomas-Ahner, Brian C. Wulff, Kathleen L. Tober, Donna F. Kusewitt, Judy A. Riggenbach and Tatiana M. Oberyszyn
    Cancer Res April 1 2007 67 (7) 3468-3474; DOI:10.1158/0008-5472.CAN-06-3798

  • Epidemiology and Prevention
    Oral Consumption of Pomegranate Fruit Extract Inhibits Growth and Progression of Primary Lung Tumors in Mice
    Naghma Khan, Farrukh Afaq, Mee-Hyang Kweon, KyungMann Kim and Hasan Mukhtar
    Cancer Res April 1 2007 67 (7) 3475-3482; DOI:10.1158/0008-5472.CAN-06-3941

  • Epidemiology and Prevention
    Silibinin Inhibits Inflammatory and Angiogenic Attributes in Photocarcinogenesis in SKH-1 Hairless Mice
    Mallikarjuna Gu, Rana P. Singh, Sivanandhan Dhanalakshmi, Chapla Agarwal and Rajesh Agarwal
    Cancer Res April 1 2007 67 (7) 3483-3491; DOI:10.1158/0008-5472.CAN-06-3955

Corrections

  • Corrections
    Multiple Properties of E6 Contribute to Cervical Cancer
    Cancer Res April 1 2007 67 (7) 3492-3492; DOI:10.1158/0008-5472.CAN-67-7-COR1

  • Corrections
    miRNA Hypermethylation in Cancer
    Cancer Res April 1 2007 67 (7) 3492-3492; DOI:10.1158/0008-5472.CAN-67-7-COR2

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Cancer Research: 67 (7)
April 2007
Volume 67, Issue 7
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Issue Highlights

  • Two Common Chromosome 8q24 Variants Are Associated with Increased Risk for Prostate Cancer
  • A Common 8q24 Variant in Prostate and Breast Cancer from a Large Nested Case-Control Study
  • Mammalian Tumor Xenografts Induce Neovascularization in Zebrafish Embryos
  • p18Ink4c Collaborates with Men1 to Constrain Lung Stem Cell Expansion and Suppress Non–Small-Cell Lung Cancers

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Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
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