Cancer Research: 67 (7)

Commentary

Commentary

Genetic Variation at 8q24 as a Susceptibility Factor for Prostate Cancer: Definitive Results from Epidemiologic Studies?

Elizabeth A. Platz

Cancer Res April 1 2007 67 (7) 2905-2907; DOI:10.1158/0008-5472.CAN-07-0737

Reviews

Reviews

Targeting Multiple Arms of the Apoptotic Regulatory Machinery

Yun Dai and Steven Grant

Cancer Res April 1 2007 67 (7) 2908-2911; DOI:10.1158/0008-5472.CAN-07-0082
Reviews

Tumor-Released Microvesicles as Vehicles of Immunosuppression

Roberta Valenti, Veronica Huber, Manuela Iero, Paola Filipazzi, Giorgio Parmiani and Licia Rivoltini

Cancer Res April 1 2007 67 (7) 2912-2915; DOI:10.1158/0008-5472.CAN-07-0520

Priority Reports

Priority Reports

Dual Role of Inactivating Lef1 Mutations in Epidermis: Tumor Promotion and Specification of Tumor Type

Catherin Niemann, David M. Owens, Peter Schettina and Fiona M. Watt

Cancer Res April 1 2007 67 (7) 2916-2921; DOI:10.1158/0008-5472.CAN-06-3427
Priority Reports

PRL-3 Down-regulates PTEN Expression and Signals through PI3K to Promote Epithelial-Mesenchymal Transition

Haihe Wang, Samantha Yiling Quah, Jing Ming Dong, Edward Manser, Jing Ping Tang and Qi Zeng

Cancer Res April 1 2007 67 (7) 2922-2926; DOI:10.1158/0008-5472.CAN-06-3598
Priority Reports

Mammalian Tumor Xenografts Induce Neovascularization in Zebrafish Embryos

Stefania Nicoli, Domenico Ribatti, Franco Cotelli and Marco Presta

Cancer Res April 1 2007 67 (7) 2927-2931; DOI:10.1158/0008-5472.CAN-06-4268
Priority Reports

High HSP90 Expression Is Associated with Decreased Survival in Breast Cancer

Elah Pick, Yuval Kluger, Jennifer M. Giltnane, Christopher Moeder, Robert L. Camp, David L. Rimm and Harriet M. Kluger

Cancer Res April 1 2007 67 (7) 2932-2937; DOI:10.1158/0008-5472.CAN-06-4511
Priority Reports

Materializing the Potential of Small Interfering RNA via a Tumor-Targeting Nanodelivery System

Kathleen F. Pirollo, Antonina Rait, Qi Zhou, Sung Hee Hwang, John A. Dagata, Gerald Zon, Richard I. Hogrefe, Guillermo Palchik and Esther H. Chang

Cancer Res April 1 2007 67 (7) 2938-2943; DOI:10.1158/0008-5472.CAN-06-4535
Priority Reports

Two Common Chromosome 8q24 Variants Are Associated with Increased Risk for Prostate Cancer

Liang Wang, Shannon K. McDonnell, Joshua P. Slusser, Scott J. Hebbring, Julie M. Cunningham, Steven J. Jacobsen, James R. Cerhan, Michael L. Blute, Daniel J. Schaid and Stephen N. Thibodeau

Cancer Res April 1 2007 67 (7) 2944-2950; DOI:10.1158/0008-5472.CAN-06-3186
Priority Reports

A Common 8q24 Variant in Prostate and Breast Cancer from a Large Nested Case-Control Study

Fredrick R. Schumacher, Heather Spencer Feigelson, David G. Cox, Christopher A. Haiman, Demetrius Albanes, Julie Buring, Eugenia E. Calle, Stephen J. Chanock, Graham A. Colditz, W. Ryan Diver, Alison M. Dunning, Matthew L. Freedman, John M. Gaziano, Edward Giovannucci, Sue E. Hankinson, Richard B. Hayes, Brian E. Henderson, Robert N. Hoover, Rudolf Kaaks, Timothy Key, Laurence N. Kolonel, Peter Kraft, Loic Le Marchand, Jing Ma, Malcolm C. Pike, Elio Riboli, Meir J. Stampfer, Daniel O. Stram, Gilles Thomas, Michael J. Thun, Ruth Travis, Jarmo Virtamo, Gerald Andriole, Edward Gelmann, Walter C. Willett and David J. Hunter

Cancer Res April 1 2007 67 (7) 2951-2956; DOI:10.1158/0008-5472.CAN-06-3591

Molecular Biology, Pathobiology, and Genetics

Molecular Biology, Pathobiology, and Genetics

Aurora A and B Overexpression and Centrosome Amplification in Early Estrogen-Induced Tumor Foci in the Syrian Hamster Kidney: Implications for Chromosomal Instability, Aneuploidy, and Neoplasia

Adrianne E. Hontz, Sara Antonia Li, Wilma L. Lingle, Vivian Negron, Amy Bruzek, Jeffrey L. Salisbury and Jonathan J. Li

Cancer Res April 1 2007 67 (7) 2957-2963; DOI:10.1158/0008-5472.CAN-06-3296
Molecular Biology, Pathobiology, and Genetics

Fatty Acid Synthase Inhibition Activates AMP-Activated Protein Kinase in SKOV3 Human Ovarian Cancer Cells

Weibo Zhou, Wan Fang Han, Leslie E. Landree, Jagan N. Thupari, Michael L. Pinn, Tsion Bililign, Eun Kyoung Kim, Aravinda Vadlamudi, Susan M. Medghalchi, Rajaa El Meskini, Gabriele V. Ronnett, Craig A. Townsend and Francis P. Kuhajda

Cancer Res April 1 2007 67 (7) 2964-2971; DOI:10.1158/0008-5472.CAN-06-3439
Molecular Biology, Pathobiology, and Genetics

Tumor Suppression by IFN Regulatory Factor-1 Is Mediated by Transcriptional Down-regulation of Cyclin D1

Andrea Kröger, Anja Stirnweiss, Julia Elisabeth Pulverer, Katjana Klages, Martina Grashoff, Jörg Reimann and Hansjörg Hauser

Cancer Res April 1 2007 67 (7) 2972-2981; DOI:10.1158/0008-5472.CAN-06-3564
Molecular Biology, Pathobiology, and Genetics

Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

Wee J. Chng, Shaji Kumar, Scott VanWier, Greg Ahmann, Tammy Price-Troska, Kim Henderson, Tae-Hoon Chung, Seungchan Kim, George Mulligan, Barbara Bryant, John Carpten, Morie Gertz, S. Vincent Rajkumar, Martha Lacy, Angela Dispenzieri, Robert Kyle, Philip Greipp, P. Leif Bergsagel and Rafael Fonseca

Cancer Res April 1 2007 67 (7) 2982-2989; DOI:10.1158/0008-5472.CAN-06-4046
Molecular Biology, Pathobiology, and Genetics

Isogenic Normal Basal and Luminal Mammary Epithelial Isolated by a Novel Method Show a Differential Response to Ionizing Radiation

Gudrun Huper and Jeffrey R. Marks

Cancer Res April 1 2007 67 (7) 2990-3001; DOI:10.1158/0008-5472.CAN-06-4065
Molecular Biology, Pathobiology, and Genetics

Tumor-Specific Cooperation of Retinoblastoma Protein Family and Snf5 Inactivation

Jingjing Chai, Xiangdong Lu, Virginia Godfrey, Christopher Fletcher, Charles W.M. Roberts, Terry Van Dyke and Bernard E. Weissman

Cancer Res April 1 2007 67 (7) 3002-3009; DOI:10.1158/0008-5472.CAN-06-4207
Molecular Biology, Pathobiology, and Genetics

Hyperthermia Activates a Subset of Ataxia-Telangiectasia Mutated Effectors Independent of DNA Strand Breaks and Heat Shock Protein 70 Status

Clayton R. Hunt, Raj K. Pandita, Andrei Laszlo, Ryuji Higashikubo, Manjula Agarwal, Tetsuya Kitamura, Arun Gupta, Nicole Rief, Nobuo Horikoshi, Rajeskaran Baskaran, Ji-Hoon Lee, Markus Löbrich, Tanya T. Paull, Joseph L. Roti Roti and Tej K. Pandita

Cancer Res April 1 2007 67 (7) 3010-3017; DOI:10.1158/0008-5472.CAN-06-4328
Molecular Biology, Pathobiology, and Genetics

Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase η, DNA Polymerase ι Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations

Yun Wang, Roger Woodgate, Terrence P. McManus, Samantha Mead, J. Justin McCormick and Veronica M. Maher

Cancer Res April 1 2007 67 (7) 3018-3026; DOI:10.1158/0008-5472.CAN-06-3073
Molecular Biology, Pathobiology, and Genetics

Tagging Single Nucleotide Polymorphisms in Cell Cycle Control Genes and Susceptibility to Invasive Epithelial Ovarian Cancer

Simon A. Gayther, Honglin Song, Susan J. Ramus, Susan Krüger Kjaer, Alice S. Whittemore, Lydia Quaye, Jonathan Tyrer, Danielle Shadforth, Estrid Hogdall, Claus Hogdall, Jan Blaeker, Richard DiCioccio, Valerie McGuire, Penelope M. Webb, Jonathan Beesley, Adele C. Green, David C. Whiteman, The Australian Ovarian Cancer Study Group, The Australian Cancer Study (Ovarian Cancer), Marc T. Goodman, Galina Lurie, Michael E. Carney, Francesmary Modugno, Roberta B. Ness, Robert P. Edwards, Kirsten B. Moysich, Ellen L. Goode, Fergus J. Couch, Julie M. Cunningham, Thomas A. Sellers, Anna H. Wu, Malcolm C. Pike, Edwin S. Iversen, Jeffrey R. Marks, Montserrat Garcia-Closas, Louise Brinton, Jolanta Lissowska, Beata Peplonska, Douglas F. Easton, Ian Jacobs, Bruce A.J. Ponder, Joellen Schildkraut, C. Leigh Pearce, Georgia Chenevix-Trench, Andrew Berchuck, Paul D.P. Pharoah and ; on behalf of the Ovarian Cancer Association Consortium

Cancer Res April 1 2007 67 (7) 3027-3035; DOI:10.1158/0008-5472.CAN-06-3261
Molecular Biology, Pathobiology, and Genetics

Six1 Overexpression in Ovarian Carcinoma Causes Resistance to TRAIL-Mediated Apoptosis and Is Associated with Poor Survival

Kian Behbakht, Lubna Qamar, Carrie S. Aldridge, Ricardo D. Coletta, Susan A. Davidson, Andrew Thorburn and Heide L. Ford

Cancer Res April 1 2007 67 (7) 3036-3042; DOI:10.1158/0008-5472.CAN-06-3755
Molecular Biology, Pathobiology, and Genetics

The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways

Zhaohui Feng, Wenwei Hu, Elisa de Stanchina, Angelika K. Teresky, Shengkan Jin, Scott Lowe and Arnold J. Levine

Cancer Res April 1 2007 67 (7) 3043-3053; DOI:10.1158/0008-5472.CAN-06-4149

Cell, Tumor, and Stem Cell Biology

Cell, Tumor, and Stem Cell Biology

Effect of Human Skin-Derived Stem Cells on Vessel Architecture, Tumor Growth, and Tumor Invasion in Brain Tumor Animal Models

Federica Pisati, Marzia Belicchi, Francesco Acerbi, Chiara Marchesi, Carlo Giussani, Manuela Gavina, Sophie Javerzat, Martin Hagedorn, Giorgio Carrabba, Valeria Lucini, Sergio Maria Gaini, Nereo Bresolin, Lorenzo Bello, Andreas Bikfalvi and Yvan Torrente

Cancer Res April 1 2007 67 (7) 3054-3063; DOI:10.1158/0008-5472.CAN-06-1384
Cell, Tumor, and Stem Cell Biology

RaLP, a New Member of the Src Homology and Collagen Family, Regulates Cell Migration and Tumor Growth of Metastatic Melanomas

Ernesta Fagiani, Giuseppina Giardina, Lucilla Luzi, Matteo Cesaroni, Micaela Quarto, Maria Capra, Giovanni Germano, Maria Bono, Manuela Capillo, PierGiuseppe Pelicci and Luisa Lanfrancone

Cancer Res April 1 2007 67 (7) 3064-3073; DOI:10.1158/0008-5472.CAN-06-2301
Cell, Tumor, and Stem Cell Biology

Amplification of MDS1/EVI1 and EVI1, Located in the 3q26.2 Amplicon, Is Associated with Favorable Patient Prognosis in Ovarian Cancer

Meera Nanjundan, Yasuhisa Nakayama, Kwai Wa Cheng, John Lahad, Jinsong Liu, Karen Lu, Wen-Lin Kuo, Karen Smith-McCune, David Fishman, Joe W. Gray and Gordon B. Mills

Cancer Res April 1 2007 67 (7) 3074-3084; DOI:10.1158/0008-5472.CAN-06-2366
Cell, Tumor, and Stem Cell Biology

Construction and Validation of Improved Triple Fusion Reporter Gene Vectors for Molecular Imaging of Living Subjects

Pritha Ray, Roger Tsien and Sanjiv Sam Gambhir

Cancer Res April 1 2007 67 (7) 3085-3093; DOI:10.1158/0008-5472.CAN-06-2402
Cell, Tumor, and Stem Cell Biology

E-Cadherin Cell-Cell Adhesion in Ewing Tumor Cells Mediates Suppression of Anoikis through Activation of the ErbB4 Tyrosine Kinase

Hyung-Gyoo Kang, Jasmine M. Jenabi, Jingsong Zhang, Nino Keshelava, Hiroyuki Shimada, William A. May, Tony Ng, C. Patrick Reynolds, Timothy J. Triche and Poul H.B. Sorensen

Cancer Res April 1 2007 67 (7) 3094-3105; DOI:10.1158/0008-5472.CAN-06-3259
Cell, Tumor, and Stem Cell Biology

N-Cadherin Signaling Potentiates Mammary Tumor Metastasis via Enhanced Extracellular Signal-Regulated Kinase Activation

James Hulit, Kimita Suyama, Su Chung, Rinat Keren, Georgia Agiostratidou, Weisong Shan, Xinyuan Dong, Terence M. Williams, Michael P. Lisanti, Karen Knudsen and Rachel B. Hazan

Cancer Res April 1 2007 67 (7) 3106-3116; DOI:10.1158/0008-5472.CAN-06-3401
Cell, Tumor, and Stem Cell Biology

Senescent Human Fibroblasts Increase the Early Growth of Xenograft Tumors via Matrix Metalloproteinase Secretion

Dan Liu and Peter J. Hornsby

Cancer Res April 1 2007 67 (7) 3117-3126; DOI:10.1158/0008-5472.CAN-06-3452
Cell, Tumor, and Stem Cell Biology

Systemic Targeting Inhibitor of κB Kinase Inhibits Melanoma Tumor Growth

Jinming Yang, Wei-Hua Pan, Gary A. Clawson and Ann Richmond

Cancer Res April 1 2007 67 (7) 3127-3134; DOI:10.1158/0008-5472.CAN-06-3547
Cell, Tumor, and Stem Cell Biology

Tumors Initiated by Constitutive Cdk2 Activation Exhibit Transforming Growth Factor β Resistance and Acquire Paracrine Mitogenic Stimulation during Progression

Patrick Corsino, Bradley Davis, Mary Law, Anna Chytil, Elizabeth Forrester, Peter Nørgaard, Nicole Teoh and Brian Law

Cancer Res April 1 2007 67 (7) 3135-3144; DOI:10.1158/0008-5472.CAN-06-3815
Cell, Tumor, and Stem Cell Biology

Histone Deacetylase 2 Modulates p53 Transcriptional Activities through Regulation of p53-DNA Binding Activity

Kelly Lynn Harms and Xinbin Chen

Cancer Res April 1 2007 67 (7) 3145-3152; DOI:10.1158/0008-5472.CAN-06-4397
Cell, Tumor, and Stem Cell Biology

Identification of Putative Stem Cell Markers, CD133 and CXCR4, in hTERT–Immortalized Primary Nonmalignant and Malignant Tumor-Derived Human Prostate Epithelial Cell Lines and in Prostate Cancer Specimens

Jun Miki, Bungo Furusato, Hongzhen Li, Yongpeng Gu, Hiroyuki Takahashi, Shin Egawa, Isabell A. Sesterhenn, David G. McLeod, Shiv Srivastava and Johng S. Rhim

Cancer Res April 1 2007 67 (7) 3153-3161; DOI:10.1158/0008-5472.CAN-06-4429
Cell, Tumor, and Stem Cell Biology

p18^Ink4c Collaborates with Men1 to Constrain Lung Stem Cell Expansion and Suppress Non–Small-Cell Lung Cancers

Xin-Hai Pei, Feng Bai, Matthew D. Smith and Yue Xiong

Cancer Res April 1 2007 67 (7) 3162-3170; DOI:10.1158/0008-5472.CAN-06-4517
Cell, Tumor, and Stem Cell Biology

Detection of DNA Copy Number Changes and Oncogenic Signaling Abnormalities from Gene Expression Data Reveals MYC Activation in High-Grade Papillary Renal Cell Carcinoma

Kyle A. Furge, Jindong Chen, Julie Koeman, Pamela Swiatek, Karl Dykema, Kseniji Lucin, Richard Kahnoski, Ximing J. Yang and Bin Tean Teh

Cancer Res April 1 2007 67 (7) 3171-3176; DOI:10.1158/0008-5472.CAN-06-4571
Cell, Tumor, and Stem Cell Biology

Mutant V600E BRAF Increases Hypoxia Inducible Factor-1α Expression in Melanoma

Suresh M. Kumar, Hong Yu, Robin Edwards, Lianjun Chen, Steven Kazianis, Patricia Brafford, Geza Acs, Meenhard Herlyn and Xiaowei Xu

Cancer Res April 1 2007 67 (7) 3177-3184; DOI:10.1158/0008-5472.CAN-06-3312
Cell, Tumor, and Stem Cell Biology

Nonsteroidal Anti-inflammatory Drugs Induce Colorectal Cancer Cell Apoptosis by Suppressing 14-3-3ε

Jun-Yang Liou, Dipak Ghelani, Sam Yeh and Kenneth K. Wu

Cancer Res April 1 2007 67 (7) 3185-3191; DOI:10.1158/0008-5472.CAN-06-3431
Cell, Tumor, and Stem Cell Biology

Cellular Transformation and Activation of the Phosphoinositide-3-Kinase–Akt Cascade by the ETV6-NTRK3 Chimeric Tyrosine Kinase Requires c-Src

Wook Jin, Chohee Yun, Amy Hobbie, Matthew J. Martin, Poul H.B. Sorensen and Seong-Jin Kim

Cancer Res April 1 2007 67 (7) 3192-3200; DOI:10.1158/0008-5472.CAN-06-3526

Experimental Therapeutics, Molecular Targets, and Chemical Biology

Experimental Therapeutics, Molecular Targets, and Chemical Biology

Salmonella typhimurium Lacking Ribose Chemoreceptors Localize in Tumor Quiescence and Induce Apoptosis

Rachel W. Kasinskas and Neil S. Forbes

Cancer Res April 1 2007 67 (7) 3201-3209; DOI:10.1158/0008-5472.CAN-06-2618
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Mitogen-Activated Protein Kinase Kinase Inhibition Enhances Nuclear Proapoptotic Function of p53 in Acute Myelogenous Leukemia Cells

Kensuke Kojima, Marina Konopleva, Ismael J. Samudio, Vivian Ruvolo and Michael Andreeff

Cancer Res April 1 2007 67 (7) 3210-3219; DOI:10.1158/0008-5472.CAN-06-2712
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Nuclear Factor-κB and Manganese Superoxide Dismutase Mediate Adaptive Radioresistance in Low-Dose Irradiated Mouse Skin Epithelial Cells

Ming Fan, Kazi Mokim Ahmed, Mitchell C. Coleman, Douglas R. Spitz and Jian Jian Li

Cancer Res April 1 2007 67 (7) 3220-3228; DOI:10.1158/0008-5472.CAN-06-2728
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Peroxisome Proliferator-Activated Receptor γ–Independent Suppression of Androgen Receptor Expression by Troglitazone Mechanism and Pharmacologic Exploitation

Chih-Cheng Yang, Yu-Chieh Wang, Shuo Wei, Li-Fang Lin, Chang-Shi Chen, Cheng-Chun Lee, Cheng-Chieh Lin and Ching-Shih Chen

Cancer Res April 1 2007 67 (7) 3229-3238; DOI:10.1158/0008-5472.CAN-06-2759
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

Alison Maloney, Paul A. Clarke, Soren Naaby-Hansen, Rob Stein, Jens-Oliver Koopman, Akunna Akpan, Alice Yang, Marketa Zvelebil, Rainer Cramer, Lindsay Stimson, Wynne Aherne, Udai Banerji, Ian Judson, Swee Sharp, Marissa Powers, Emmanuel deBilly, Joanne Salmons, Michael Walton, Al Burlingame, Michael Waterfield and Paul Workman

Cancer Res April 1 2007 67 (7) 3239-3253; DOI:10.1158/0008-5472.CAN-06-2968
Experimental Therapeutics, Molecular Targets, and Chemical Biology

The Aryl Propionic Acid R-Flurbiprofen Selectively Induces p75^NTR-Dependent Decreased Survival of Prostate Tumor Cells

Emily J. Quann, Fatima Khwaja, Kenton H. Zavitz and Daniel Djakiew

Cancer Res April 1 2007 67 (7) 3254-3262; DOI:10.1158/0008-5472.CAN-06-3657
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Isoleucine, an Essential Amino Acid, Prevents Liver Metastases of Colon Cancer by Antiangiogenesis

Kazumoto Murata and Masami Moriyama

Cancer Res April 1 2007 67 (7) 3263-3268; DOI:10.1158/0008-5472.CAN-06-3739
Experimental Therapeutics, Molecular Targets, and Chemical Biology

IFN-γ Enhances the Antimyeloma Activity of the Fully Human Anti–Human Leukocyte Antigen-DR Monoclonal Antibody 1D09C3

Carmelo Carlo-Stella, Anna Guidetti, Massimo Di Nicola, Cristiana Lavazza, Loredana Cleris, Daniela Sia, Paolo Longoni, Marco Milanesi, Michele Magni, Zoltan Nagy, Paolo Corradini, Antonino Carbone, Franca Formelli and Alessandro M. Gianni

Cancer Res April 1 2007 67 (7) 3269-3275; DOI:10.1158/0008-5472.CAN-06-3744
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Oncogenic Role of MPHOSPH1, a Cancer-Testis Antigen Specific to Human Bladder Cancer

Mitsugu Kanehira, Toyomasa Katagiri, Arata Shimo, Ryo Takata, Taro Shuin, Tsuneharu Miki, Tomoaki Fujioka and Yusuke Nakamura

Cancer Res April 1 2007 67 (7) 3276-3285; DOI:10.1158/0008-5472.CAN-06-3748
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Regulation of Vascular Endothelial Growth Factor Receptor-1 Expression by Specificity Proteins 1, 3, and 4 in Pancreatic Cancer Cells

Maen Abdelrahim, Cheryl H. Baker, James L. Abbruzzese, David Sheikh-Hamad, Shengxi Liu, Sung Dae Cho, Kyungsil Yoon and Stephen Safe

Cancer Res April 1 2007 67 (7) 3286-3294; DOI:10.1158/0008-5472.CAN-06-3831
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Positron Emission Tomography of Herpes Simplex Virus 1 Oncolysis

Darshini Kuruppu, Anna-Liisa Brownell, Aijun Zhu, Meixiang Yu, Xukui Wang, Yakup Kulu, Bryan C. Fuchs, Hiroshi Kawasaki and Kenneth K. Tanabe

Cancer Res April 1 2007 67 (7) 3295-3300; DOI:10.1158/0008-5472.CAN-06-4062
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Repression of IFN Regulatory Factor 8 by DNA Methylation Is a Molecular Determinant of Apoptotic Resistance and Metastatic Phenotype in Metastatic Tumor Cells

Dafeng Yang, Muthusamy Thangaraju, Kristy Greeneltch, Darren D. Browning, Patricia V. Schoenlein, Tomohiko Tamura, Keiko Ozato, Vadivel Ganapathy, Scott I. Abrams and Kebin Liu

Cancer Res April 1 2007 67 (7) 3301-3309; DOI:10.1158/0008-5472.CAN-06-4068
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Inhibition of Angiogenesis and Invasion by 3,3′-Diindolylmethane Is Mediated by the Nuclear Factor–κB Downstream Target Genes MMP-9 and uPA that Regulated Bioavailability of Vascular Endothelial Growth Factor in Prostate Cancer

Dejuan Kong, Yiwei Li, Zhiwei Wang, Sanjeev Banerjee and Fazlul H. Sarkar

Cancer Res April 1 2007 67 (7) 3310-3319; DOI:10.1158/0008-5472.CAN-06-4277
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Gene Expression Signature of Human Cancer Cell Lines Treated with the Ras Inhibitor Salirasib (S-Farnesylthiosalicylic Acid)

Roy Blum, Ran Elkon, Shira Yaari, Adi Zundelevich, Jasmine Jacob-Hirsch, Gideon Rechavi, Ron Shamir and Yoel Kloog

Cancer Res April 1 2007 67 (7) 3320-3328; DOI:10.1158/0008-5472.CAN-06-4287
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Systematic Urokinase-Activated Anthrax Toxin Therapy Produces Regressions of Subcutaneous Human Non–Small Cell Lung Tumor in Athymic Nude Mice

Yunpeng Su, Janelle Ortiz, Shihui Liu, Thomas H. Bugge, Ravibhushan Singh, Stephen H. Leppla and Arthur E. Frankel

Cancer Res April 1 2007 67 (7) 3329-3336; DOI:10.1158/0008-5472.CAN-06-4642
Experimental Therapeutics, Molecular Targets, and Chemical Biology

A Peptide Conjugate of Vitamin E Succinate Targets Breast Cancer Cells with High ErbB2 Expression

Xiu-Fang Wang, Marc Birringer, Lan-Feng Dong, Pavel Veprek, Pauline Low, Emma Swettenham, Marina Stantic, Lin-Hong Yuan, Renata Zobalova, Kun Wu, Miroslav Ledvina, Stephen J. Ralph and Jiri Neuzil

Cancer Res April 1 2007 67 (7) 3337-3344; DOI:10.1158/0008-5472.CAN-06-2480
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Enhanced Expression of Asparagine Synthetase under Glucose-Deprived Conditions Protects Pancreatic Cancer Cells from Apoptosis Induced by Glucose Deprivation and Cisplatin

Hongyan Cui, Stephanie Darmanin, Mitsuteru Natsuisaka, Takeshi Kondo, Masahiro Asaka, Masanobu Shindoh, Fumihiro Higashino, Junji Hamuro, Futoshi Okada, Masataka Kobayashi, Koji Nakagawa, Hideyuki Koide and Masanobu Kobayashi

Cancer Res April 1 2007 67 (7) 3345-3355; DOI:10.1158/0008-5472.CAN-06-2519
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Induction of Cdc25B Regulates Cell Cycle Resumption after Genotoxic Stress

Pallavi Bansal and John S. Lazo

Cancer Res April 1 2007 67 (7) 3356-3363; DOI:10.1158/0008-5472.CAN-06-3685
Experimental Therapeutics, Molecular Targets, and Chemical Biology

2-Deoxy-d-Glucose Combined with Cisplatin Enhances Cytotoxicity via Metabolic Oxidative Stress in Human Head and Neck Cancer Cells

Andrean L. Simons, Iman M. Ahmad, David M. Mattson, Kenneth J. Dornfeld and Douglas R. Spitz

Cancer Res April 1 2007 67 (7) 3364-3370; DOI:10.1158/0008-5472.CAN-06-3717
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Parthenolide Inhibits Tubulin Carboxypeptidase Activity

Xavier Fonrose, Frédéric Ausseil, Emmanuelle Soleilhac, Véronique Masson, Bruno David, Isabelle Pouny, Jean-Christophe Cintrat, Bernard Rousseau, Caroline Barette, Georges Massiot and Laurence Lafanechère

Cancer Res April 1 2007 67 (7) 3371-3378; DOI:10.1158/0008-5472.CAN-06-3732
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Cholesterol Starvation Induces Differentiation of Human Leukemia HL-60 Cells

Carolina C. Sánchez-Martín, Alberto Dávalos, Covadonga Martín-Sánchez, Gema de la Peña, Carlos Fernández-Hernando and Miguel A. Lasunción

Cancer Res April 1 2007 67 (7) 3379-3386; DOI:10.1158/0008-5472.CAN-06-4093
Experimental Therapeutics, Molecular Targets, and Chemical Biology

Improvement of Antitumor Activity by Gene Amplification with a Replicating but Nondisseminating Adenovirus

Denis Bourbeau, Cara Jean Lau, Jairo Jaime, Zafiro Koty, Simone P. Zehntner, Geneviève Lavoie, Anne-Marie Mes-Masson, Josephine Nalbantoglu and Bernard Massie

Cancer Res April 1 2007 67 (7) 3387-3395; DOI:10.1158/0008-5472.CAN-06-4317

Immunology

Immunology

CXCL10 Promotes Invasion-Related Properties in Human Colorectal Carcinoma Cells

Adi Zipin-Roitman, Tsipi Meshel, Orit Sagi-Assif, Bruria Shalmon, Camila Avivi, Raphael M. Pfeffer, Isaac P. Witz and Adit Ben-Baruch

Cancer Res April 1 2007 67 (7) 3396-3405; DOI:10.1158/0008-5472.CAN-06-3087
Immunology

Active Induction of Tumor-Specific IgE Antibodies by Oral Mimotope Vaccination

Angelika B. Riemer, Eva Untersmayr, Regina Knittelfelder, Albert Duschl, Hubert Pehamberger, Christoph C. Zielinski, Otto Scheiner and Erika Jensen-Jarolim

Cancer Res April 1 2007 67 (7) 3406-3411; DOI:10.1158/0008-5472.CAN-06-3758

Endocrinology

Endocrinology

Evidences that Leptin Up-regulates E-Cadherin Expression in Breast Cancer: Effects on Tumor Growth and Progression

Loredana Mauro, Stefania Catalano, Gianluca Bossi, Michele Pellegrino, Ines Barone, Sara Morales, Cinzia Giordano, Viviana Bartella, Ivan Casaburi and Sebastiano Andò

Cancer Res April 1 2007 67 (7) 3412-3421; DOI:10.1158/0008-5472.CAN-06-2890
Endocrinology

Androgen Deprivation Increases p300 Expression in Prostate Cancer Cells

Hannelore V. Heemers, Thomas J. Sebo, Jose D. Debes, Kevin M. Regan, Kristin A. Raclaw, Linda M. Murphy, Alfred Hobisch, Zoran Culig and Donald J. Tindall

Cancer Res April 1 2007 67 (7) 3422-3430; DOI:10.1158/0008-5472.CAN-06-2836

Clinical Research

Clinical Research

Phosphoprotein Pathway Mapping: Akt/Mammalian Target of Rapamycin Activation Is Negatively Associated with Childhood Rhabdomyosarcoma Survival

Emanuel F. Petricoin III, Virginia Espina, Robyn P. Araujo, Brieanne Midura, Choh Yeung, Xiaolin Wan, Gabriel S. Eichler, Donald J. Johann Jr., Stephen Qualman, Maria Tsokos, Kartik Krishnan, Lee J. Helman and Lance A. Liotta

Cancer Res April 1 2007 67 (7) 3431-3440; DOI:10.1158/0008-5472.CAN-06-1344
Clinical Research

Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers

Stuart C. Winter, Francesca M. Buffa, Priyamal Silva, Crispin Miller, Helen R. Valentine, Helen Turley, Ketan A. Shah, Graham J. Cox, Rogan J. Corbridge, Jarrod J. Homer, Brian Musgrove, Nick Slevin, Philip Sloan, Pat Price, Catharine M.L. West and Adrian L. Harris

Cancer Res April 1 2007 67 (7) 3441-3449; DOI:10.1158/0008-5472.CAN-06-3322
Clinical Research

A High-Throughput Study in Melanoma Identifies Epithelial-Mesenchymal Transition as a Major Determinant of Metastasis

Soledad R. Alonso, Lorraine Tracey, Pablo Ortiz, Beatriz Pérez-Gómez, José Palacios, Marina Pollán, Juan Linares, Salvio Serrano, Ana I. Sáez-Castillo, Lydia Sánchez, Raquel Pajares, Abel Sánchez-Aguilera, Maria J. Artiga, Miguel A. Piris and José L. Rodríguez-Peralto

Cancer Res April 1 2007 67 (7) 3450-3460; DOI:10.1158/0008-5472.CAN-06-3481
Clinical Research

Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma

Guoan Chen, Xiaoju Wang, Jianjun Yu, Sooryanarayana Varambally, Jindan Yu, Dafydd G. Thomas, Mu-Yen Lin, Prakash Vishnu, Zhuwen Wang, Rui Wang, Jeff Fielhauer, Debashis Ghosh, Thomas J. Giordano, Donald Giacherio, Andrew C. Chang, Mark B. Orringer, Talal El-Hefnawy, William L. Bigbee, David G. Beer and Arul M. Chinnaiyan

Cancer Res April 1 2007 67 (7) 3461-3467; DOI:10.1158/0008-5472.CAN-06-4475

Epidemiology and Prevention

Epidemiology and Prevention

Gender Differences in UVB-Induced Skin Carcinogenesis, Inflammation, and DNA Damage

Jennifer M. Thomas-Ahner, Brian C. Wulff, Kathleen L. Tober, Donna F. Kusewitt, Judy A. Riggenbach and Tatiana M. Oberyszyn

Cancer Res April 1 2007 67 (7) 3468-3474; DOI:10.1158/0008-5472.CAN-06-3798
Epidemiology and Prevention

Oral Consumption of Pomegranate Fruit Extract Inhibits Growth and Progression of Primary Lung Tumors in Mice

Naghma Khan, Farrukh Afaq, Mee-Hyang Kweon, KyungMann Kim and Hasan Mukhtar

Cancer Res April 1 2007 67 (7) 3475-3482; DOI:10.1158/0008-5472.CAN-06-3941
Epidemiology and Prevention

Silibinin Inhibits Inflammatory and Angiogenic Attributes in Photocarcinogenesis in SKH-1 Hairless Mice

Mallikarjuna Gu, Rana P. Singh, Sivanandhan Dhanalakshmi, Chapla Agarwal and Rajesh Agarwal

Cancer Res April 1 2007 67 (7) 3483-3491; DOI:10.1158/0008-5472.CAN-06-3955

Corrections

Corrections

Multiple Properties of E6 Contribute to Cervical Cancer

Cancer Res April 1 2007 67 (7) 3492-3492; DOI:10.1158/0008-5472.CAN-67-7-COR1
Corrections

miRNA Hypermethylation in Cancer

Cancer Res April 1 2007 67 (7) 3492-3492; DOI:10.1158/0008-5472.CAN-67-7-COR2

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