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Table of Contents

Reviews

  • Reviews
    Cannabinoids for Cancer Treatment: Progress and Promise
    Sami Sarfaraz, Vaqar M. Adhami, Deeba N. Syed, Farrukh Afaq and Hasan Mukhtar
    Cancer Res January 15 2008 68 (2) 339-342; DOI:10.1158/0008-5472.CAN-07-2785

  • Reviews
    Acquired Lymphedema: An Urgent Need for Adequate Animal Models
    Catarina Hadamitzky and Reinhard Pabst
    Cancer Res January 15 2008 68 (2) 343-345; DOI:10.1158/0008-5472.CAN-07-2454

Priority Reports

  • Priority Reports
    Nerve Growth Factor Is a Potential Therapeutic Target in Breast Cancer
    Eric Adriaenssens, Elsa Vanhecke, Pasquine Saule, Alexandra Mougel, Adeline Page, Rodrigue Romon, Victor Nurcombe, Xuefen Le Bourhis and Hubert Hondermarck
    Cancer Res January 15 2008 68 (2) 346-351; DOI:10.1158/0008-5472.CAN-07-1183

  • Priority Reports
    p53-Dependent and p53-Independent Activation of Autophagy by ARF
    Wassim M. Abida and Wei Gu
    Cancer Res January 15 2008 68 (2) 352-357; DOI:10.1158/0008-5472.CAN-07-2069

  • Priority Reports
    Multiple Rare Nonsynonymous Variants in the Adenomatous Polyposis Coli Gene Predispose to Colorectal Adenomas
    Duncan Azzopardi, Anthony R. Dallosso, Kristilyn Eliason, Brant C. Hendrickson, Natalie Jones, Edward Rawstorne, James Colley, Valentina Moskvina, Cynthia Frye, Julian R. Sampson, Richard Wenstrup, Thomas Scholl and Jeremy P. Cheadle
    Cancer Res January 15 2008 68 (2) 358-363; DOI:10.1158/0008-5472.CAN-07-5733

  • Priority Reports
    Activating Transcription Factor 3 Is a Novel Repressor of the Nuclear Factor Erythroid-Derived 2–Related Factor 2 (Nrf2)–Regulated Stress Pathway
    Stephan L. Brown, Konjeti R. Sekhar, Girish Rachakonda, Soumya Sasi and Michael L. Freeman
    Cancer Res January 15 2008 68 (2) 364-368; DOI:10.1158/0008-5472.CAN-07-2170

Molecular Biology, Pathobiology, and Genetics

  • Molecular Biology, Pathobiology, and Genetics
    Revealing Targeted Therapy for Human Cancer by Gene Module Maps
    David J. Wong, Dimitry S.A. Nuyten, Aviv Regev, Meihong Lin, Adam S. Adler, Eran Segal, Marc J. van de Vijver and Howard Y. Chang
    Cancer Res January 15 2008 68 (2) 369-378; DOI:10.1158/0008-5472.CAN-07-0382

  • Molecular Biology, Pathobiology, and Genetics
    Regulation of Gastric Carcinogenesis by Helicobacter pylori Virulence Factors
    Aime T. Franco, Elizabeth Johnston, Uma Krishna, Yoshio Yamaoka, Dawn A. Israel, Toni A. Nagy, Lydia E. Wroblewski, Maria Blanca Piazuelo, Pelayo Correa and Richard M. Peek Jr.
    Cancer Res January 15 2008 68 (2) 379-387; DOI:10.1158/0008-5472.CAN-07-0824

  • Molecular Biology, Pathobiology, and Genetics
    α2-6–Linked Sialic Acids on N-Glycans Modulate Carcinoma Differentiation In vivo
    Maria Hedlund, Elisa Ng, Ajit Varki and Nissi M. Varki
    Cancer Res January 15 2008 68 (2) 388-394; DOI:10.1158/0008-5472.CAN-07-1340

  • Molecular Biology, Pathobiology, and Genetics
    t-Darpp Promotes Cancer Cell Survival by Up-regulation of Bcl2 through Akt-Dependent Mechanism
    Abbes Belkhiri, Altaf A. Dar, Alexander Zaika, Mark Kelley and Wael El-Rifai
    Cancer Res January 15 2008 68 (2) 395-403; DOI:10.1158/0008-5472.CAN-07-1580

  • Molecular Biology, Pathobiology, and Genetics
    The Kringle 1 Domain of Hepatocyte Growth Factor Has Antiangiogenic and Antitumor Cell Effects on Hepatocellular Carcinoma
    Zan Shen, Zhen Fan Yang, Yi Gao, Ji Cheng Li, Hai Xiao Chen, Ching Chiu Liu, Ronnie T.P. Poon, Sheung Tat Fan, John M. Luk, Kong Hung Sze, Tsai Ping Li, Ren Bao Gan, Ming Liang He, Hsiang Fu Kung and Marie C.M. Lin
    Cancer Res January 15 2008 68 (2) 404-414; DOI:10.1158/0008-5472.CAN-07-2081

  • Molecular Biology, Pathobiology, and Genetics
    Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen
    Sally A. Amundson, Khanh T. Do, Lisa C. Vinikoor, R. Anthony Lee, Christine A. Koch-Paiz, Jaeyong Ahn, Mark Reimers, Yidong Chen, Dominic A. Scudiero, John N. Weinstein, Jeffrey M. Trent, Michael L. Bittner, Paul S. Meltzer and Albert J. Fornace Jr.
    Cancer Res January 15 2008 68 (2) 415-424; DOI:10.1158/0008-5472.CAN-07-2120

  • Molecular Biology, Pathobiology, and Genetics
    MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
    Hua Yang, William Kong, Lili He, Jian-Jun Zhao, Joshua D. O'Donnell, Jiawang Wang, Robert M. Wenham, Domenico Coppola, Patricia A. Kruk, Santo V. Nicosia and Jin Q. Cheng
    Cancer Res January 15 2008 68 (2) 425-433; DOI:10.1158/0008-5472.CAN-07-2488

  • Molecular Biology, Pathobiology, and Genetics
    Glioma Pathogenesis-Related Protein 1 Exerts Tumor Suppressor Activities through Proapoptotic Reactive Oxygen Species–c-Jun–NH2 Kinase Signaling
    Likun Li, ElMoataz Abdel Fattah, Guangwen Cao, Chengzhen Ren, Guang Yang, Alexei A. Goltsov, A. Craig Chinault, Wei-Wen Cai, Terry L. Timme and Timothy C. Thompson
    Cancer Res January 15 2008 68 (2) 434-443; DOI:10.1158/0008-5472.CAN-07-2931

  • Molecular Biology, Pathobiology, and Genetics
    Mammalian Target of Rapamycin Is the Key Effector of Phosphatidylinositol-3-OH–Initiated Proliferative Signals in the Thyroid Follicular Epithelium
    Nicole Yeager, Charlene Brewer, Kathy Qi Cai, Xiang-Xi Xu and Antonio Di Cristofano
    Cancer Res January 15 2008 68 (2) 444-449; DOI:10.1158/0008-5472.CAN-07-3030

  • Molecular Biology, Pathobiology, and Genetics
    Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling
    Philip J. Coates, Jana K. Rundle, Sally A. Lorimore and Eric G. Wright
    Cancer Res January 15 2008 68 (2) 450-456; DOI:10.1158/0008-5472.CAN-07-3050

  • Molecular Biology, Pathobiology, and Genetics
    Regulation of Vascular Endothelial Growth Factor D by Orphan Receptors Hepatocyte Nuclear Factor-4α and Chicken Ovalbumin Upstream Promoter Transcription Factors 1 and 2
    Georgia Schäfer, Christoph Wißmann, Johannes Hertel, Victoria Lunyak and Michael Höcker
    Cancer Res January 15 2008 68 (2) 457-466; DOI:10.1158/0008-5472.CAN-07-5136

Cell, Tumor, and Stem Cell Biology

  • Cell, Tumor, and Stem Cell Biology
    Cyclooxygenase-2 Expression during Immortalization and Breast Cancer Progression
    Xiangshan Zhao, Monica Goswami, Nidhi Pokhriyal, Hui Ma, Hongyan Du, Jun Yao, Thomas A. Victor, Kornelia Polyak, Charles D. Sturgis, Hamid Band and Vimla Band
    Cancer Res January 15 2008 68 (2) 467-475; DOI:10.1158/0008-5472.CAN-07-0782

  • Cell, Tumor, and Stem Cell Biology
    p19Arf Inhibits the Invasion of Hepatocellular Carcinoma Cells by Binding to C-terminal Binding Protein
    Ya-Wen Chen, Seema Paliwal, Kyle Draheim, Steven R. Grossman and Brian C. Lewis
    Cancer Res January 15 2008 68 (2) 476-482; DOI:10.1158/0008-5472.CAN-07-1960

  • Cell, Tumor, and Stem Cell Biology
    Hyaluronic Acid Synthase-1 Expression Regulates Bladder Cancer Growth, Invasion, and Angiogenesis through CD44
    Roozbeh Golshani, Luis Lopez, Veronica Estrella, Mario Kramer, Naoko Iida and Vinata B. Lokeshwar
    Cancer Res January 15 2008 68 (2) 483-491; DOI:10.1158/0008-5472.CAN-07-2140

  • Cell, Tumor, and Stem Cell Biology
    The Adenocarcinoma-Associated Antigen, AGR2, Promotes Tumor Growth, Cell Migration, and Cellular Transformation
    Zheng Wang, Ying Hao and Anson W. Lowe
    Cancer Res January 15 2008 68 (2) 492-497; DOI:10.1158/0008-5472.CAN-07-2930

  • Cell, Tumor, and Stem Cell Biology
    Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development
    Dezheng Dong, Min Ni, Jianze Li, Shigang Xiong, Wei Ye, Jenilyn J. Virrey, Changhui Mao, Risheng Ye, Miao Wang, Ligaya Pen, Louis Dubeau, Susan Groshen, Florence M. Hofman and Amy S. Lee
    Cancer Res January 15 2008 68 (2) 498-505; DOI:10.1158/0008-5472.CAN-07-2950

  • Cell, Tumor, and Stem Cell Biology
    CSN5 Isopeptidase Activity Links COP9 Signalosome Activation to Breast Cancer Progression
    Adam S. Adler, Laurie E. Littlepage, Meihong Lin, Tiara L.A. Kawahara, David J. Wong, Zena Werb and Howard Y. Chang
    Cancer Res January 15 2008 68 (2) 506-515; DOI:10.1158/0008-5472.CAN-07-3060

  • Cell, Tumor, and Stem Cell Biology
    Induction of Cancer Metastasis by Cyclophosphamide Pretreatment of Host Mice: An Opposite Effect of Chemotherapy
    Kensuke Yamauchi, Meng Yang, Katsuhiro Hayashi, Ping Jiang, Norio Yamamoto, Hiroyuki Tsuchiya, Katsuro Tomita, Abdool R. Moossa, Michael Bouvet and Robert M. Hoffman
    Cancer Res January 15 2008 68 (2) 516-520; DOI:10.1158/0008-5472.CAN-07-3063

  • Cell, Tumor, and Stem Cell Biology
    Vascular Endothelial Growth Factor–Mediated Decrease in Plasma Soluble Vascular Endothelial Growth Factor Receptor-2 Levels as a Surrogate Biomarker for Tumor Growth
    John M.L. Ebos, Christina R. Lee, Elena Bogdanovic, Jennifer Alami, Paul Van Slyke, Giulio Francia, Ping Xu, Anthony J. Mutsaers, Daniel J. Dumont and Robert S. Kerbel
    Cancer Res January 15 2008 68 (2) 521-529; DOI:10.1158/0008-5472.CAN-07-3217

  • Cell, Tumor, and Stem Cell Biology
    Development of a New Tracking Tool for the Human Monomeric Laminin-γ2 Chain In vitro and In vivo
    Naohiko Koshikawa, Tomoko Minegishi, Kazuki Nabeshima and Motoharu Seiki
    Cancer Res January 15 2008 68 (2) 530-536; DOI:10.1158/0008-5472.CAN-07-5269

  • Cell, Tumor, and Stem Cell Biology
    The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer
    Simone Spaderna, Otto Schmalhofer, Mandy Wahlbuhl, Arno Dimmler, Katja Bauer, Aneesa Sultan, Falk Hlubek, Andreas Jung, Dennis Strand, Andreas Eger, Thomas Kirchner, Jürgen Behrens and Thomas Brabletz
    Cancer Res January 15 2008 68 (2) 537-544; DOI:10.1158/0008-5472.CAN-07-5682

  • Cell, Tumor, and Stem Cell Biology
    Regulation of Angiogenic Factors by HDM2 in Renal Cell Carcinoma
    Veronica A. Carroll and Margaret Ashcroft
    Cancer Res January 15 2008 68 (2) 545-552; DOI:10.1158/0008-5472.CAN-06-4738

Experimental Therapeutics, Molecular Targets, and Chemical Biology

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Cyclooxygenase-2–Derived Prostaglandin E2 Activates β-Catenin in Human Cholangiocarcinoma Cells: Evidence for Inhibition of These Signaling Pathways by ω3 Polyunsaturated Fatty Acids
    Kyu Lim, Chang Han, Lihong Xu, Kumiko Isse, Anthony J. Demetris and Tong Wu
    Cancer Res January 15 2008 68 (2) 553-560; DOI:10.1158/0008-5472.CAN-07-2295

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Antibody-Mediated Blockade of Integrin αvβ6 Inhibits Tumor Progression In vivo by a Transforming Growth Factor-β–Regulated Mechanism
    Louise A. Koopman Van Aarsen, Diane R. Leone, Steffan Ho, Brian M. Dolinski, Patricia E. McCoon, Doreen J. LePage, Rebecca Kelly, Glenna Heaney, Paul Rayhorn, Carl Reid, Kenneth J. Simon, Gerald S. Horan, Nianjun Tao, Humphrey A. Gardner, Marilyn M. Skelly, Allen M. Gown, Gareth J. Thomas, Paul H. Weinreb, Stephen E. Fawell and Shelia M. Violette
    Cancer Res January 15 2008 68 (2) 561-570; DOI:10.1158/0008-5472.CAN-07-2307

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Impact of Common Epidermal Growth Factor Receptor and HER2 Variants on Receptor Activity and Inhibition by Lapatinib
    Tona M. Gilmer, Louann Cable, Krystal Alligood, David Rusnak, Glenn Spehar, Kathleen T. Gallagher, Ermias Woldu, H. Luke Carter, Anne T. Truesdale, Lisa Shewchuk and Edgar R. Wood
    Cancer Res January 15 2008 68 (2) 571-579; DOI:10.1158/0008-5472.CAN-07-2404

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Phosphatidylinositol Ether Lipid Analogues Induce AMP-Activated Protein Kinase–Dependent Death in LKB1-Mutant Non–Small Cell Lung Cancer Cells
    Regan M. Memmott, Joell J. Gills, Melinda Hollingshead, Margaret C. Powers, Zhiping Chen, Bruce Kemp, Alan Kozikowski and Phillip A. Dennis
    Cancer Res January 15 2008 68 (2) 580-588; DOI:10.1158/0008-5472.CAN-07-3091

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel
    Ayana Sawai, Sarat Chandarlapaty, Heidi Greulich, Mithat Gonen, Qing Ye, Carlos L. Arteaga, William Sellers, Neal Rosen and David B. Solit
    Cancer Res January 15 2008 68 (2) 589-596; DOI:10.1158/0008-5472.CAN-07-1570

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Superior Activity of Fusion Protein scFvRit:sFasL over Cotreatment with Rituximab and Fas Agonists
    Edwin Bremer, Bram ten Cate, Douwe F. Samplonius, Nicole Mueller, Harald Wajant, Alja J. Stel, Martine Chamuleau, Arjan A. van de Loosdrecht, Julia Stieglmaier, Georg H. Fey and Wijnand Helfrich
    Cancer Res January 15 2008 68 (2) 597-604; DOI:10.1158/0008-5472.CAN-07-5171

  • Experimental Therapeutics, Molecular Targets, and Chemical Biology
    Chronic Hypoxia Decreases Synthesis of Homologous Recombination Proteins to Offset Chemoresistance and Radioresistance
    Norman Chan, Marianne Koritzinsky, Helen Zhao, Ranjit Bindra, Peter M. Glazer, Simon Powell, Abdellah Belmaaza, Brad Wouters and Robert G. Bristow
    Cancer Res January 15 2008 68 (2) 605-614; DOI:10.1158/0008-5472.CAN-07-5472

Immunology

  • Immunology
    Protective Role of Toll-like Receptor 4 during the Initiation Stage of Cutaneous Chemical Carcinogenesis
    Nabiha Yusuf, Tahseen H. Nasti, J. Alan Long, Mohammed Naseemuddin, Alan P. Lucas, Hui Xu and Craig A. Elmets
    Cancer Res January 15 2008 68 (2) 615-622; DOI:10.1158/0008-5472.CAN-07-5219

Letters to the Editor

  • Letters to the Editor
    Is Mitochondrial DNA Variation Associated with Sporadic Breast Cancer Risk?
    Ana Mosquera-Miguel, Vanesa Álvarez-Iglesias, Ángel Carracedo, Antonio Salas, Ana Vega, Ángel Carracedo, Roger Milne, Antonio Cabrera de León, Javier Benitez, Ángel Carracedo and Antonio Salas
    Cancer Res January 15 2008 68 (2) 623-625; DOI:10.1158/0008-5472.CAN-07-2385

  • Letters to the Editor
    Ren-Kui Bai, Suzanne M. Leal, Daniel Covarrubias, Lee-Jun C. Wong, Daniel Covarrubias and Aiyi Liu
    Cancer Res January 15 2008 68 (2) 624-624; DOI:10.1158/0008-5472.CAN-07-5706

Correction

  • Correction
    Correction: MDSC and ATRA
    Cancer Res January 15 2008 68 (2) 626-626; DOI:10.1158/0008-5472.CAN-68-2-COR

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Cancer Research: 68 (2)
January 2008
Volume 68, Issue 2
  • Table of Contents
  • Table of Contents (PDF)
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  • January 15 Cancer Research Highlights

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Issue Highlights

  • Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen
  • Revealing Targeted Therapy for Human Cancer by Gene Module Maps
  • Vascular Endothelial Growth Factor–Mediated Decrease in Plasma Soluble Vascular Endothelial Growth Factor Receptor-2 Levels as a Surrogate Biomarker for Tumor Growth

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Cancer Research Online ISSN: 1538-7445
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