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Clinical Research

A New Model for Prediction of Drug Distribution in Tumor and Normal Tissues: Pharmacokinetics of Temozolomide in Glioma Patients

Lula Rosso, Cathryn S. Brock, James M. Gallo, Azeem Saleem, Patricia M. Price, Federico E. Turkheimer and Eric O. Aboagye
Lula Rosso
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Cathryn S. Brock
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James M. Gallo
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Azeem Saleem
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Patricia M. Price
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Federico E. Turkheimer
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Eric O. Aboagye
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DOI: 10.1158/0008-5472.CAN-08-2356 Published January 2009
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Volume 69, Issue 1, pp. 120-127

DOI 
https://doi.org/10.1158/0008-5472.CAN-08-2356
PubMed 
19117994

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received June 23, 2008
  • Revision received September 16, 2008
  • Accepted October 16, 2008
  • Published first December 31, 2008.

Copyright & Usage 
©2009 American Association for Cancer Research.

Author Information

  1. Lula Rosso1,
  2. Cathryn S. Brock1,2,
  3. James M. Gallo4,
  4. Azeem Saleem1,3,
  5. Patricia M. Price1,3,
  6. Federico E. Turkheimer1, and
  7. Eric O. Aboagye1
  1. 1Clinical Sciences Centre, Imperial College, Faculty of Medicine, Hammersmith Hospital Campus; 2Imperial College Healthcare NHS Trust, London, United Kingdom; 3Academic Department of Radiation Oncology, Christie Hospital NHS Trust, Manchester, United Kingdom; and 4Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, Pennsylvania
  1. Requests for reprints:
    Eric O. Aboagye, Molecular Therapy and PET Oncology Research Group, Imperial College London, Faculty of Medicine, Hammersmith Hospital, Room 240 MRC Cyclotron Building, Du Cane Road, London W12 ONN, United Kingdom. Phone: 44-208-383-3759; Fax: 44-208-383-1783; E-mail: eric.aboagye{at}imperial.ac.uk.
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Cancer Research: 69 (1)
January 2009
Volume 69, Issue 1
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A New Model for Prediction of Drug Distribution in Tumor and Normal Tissues: Pharmacokinetics of Temozolomide in Glioma Patients
Lula Rosso, Cathryn S. Brock, James M. Gallo, Azeem Saleem, Patricia M. Price, Federico E. Turkheimer and Eric O. Aboagye
Cancer Res January 1 2009 (69) (1) 120-127; DOI: 10.1158/0008-5472.CAN-08-2356

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A New Model for Prediction of Drug Distribution in Tumor and Normal Tissues: Pharmacokinetics of Temozolomide in Glioma Patients
Lula Rosso, Cathryn S. Brock, James M. Gallo, Azeem Saleem, Patricia M. Price, Federico E. Turkheimer and Eric O. Aboagye
Cancer Res January 1 2009 (69) (1) 120-127; DOI: 10.1158/0008-5472.CAN-08-2356
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Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
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