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Volume 69, Issue 4, pp. 1259-1262
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History
- Received September 29, 2008
- Accepted November 21, 2008
- Published first February 10, 2009.
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- Previous version (February 10, 2009 - 10:47).
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©2009 American Association for Cancer Research.
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February 2009
Volume 69, Issue 4
Volume 69, Issue 4
Is Anticancer Drug Development Heading in the Right Direction?
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- Article
- Abstract
- Background
- Molecular Targeting
- Alternative Strategies
- Conclusions
- Disclosure of Potential Conflicts of Interest
- Acknowledgments
- Footnotes
- References
- The Pace of New Drug Approvals Is Too Slow
- Human Cancers Are Characterized by Numerous Genetic Mutations
- Solid Tumors Are More Difficult to Treat than Liquid Tumors
- Monotherapy Will Be Less Effective than Combinations
- Cells Grown on Plastic Are Not Ideal Models for Complex Human Cancers
- Drug Selectivity Is a Relative Term
- Both the Targeted and Unsupervised Approaches Should Be Pursued
- Drug Distribution, Metabolism, and Uptake Are Critically Important
- Figures & Data
- Info & Metrics
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