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Therapeutics, Targets, and Chemical Biology

Venetoclax Synergizes with Radiotherapy for Treatment of B-cell Lymphomas

Shyril O'Steen, Damian J. Green, Ajay K. Gopal, Johnnie J. Orozco, Aimee L. Kenoyer, Yukang Lin, D. Scott Wilbur, Donald K. Hamlin, Darrell R. Fisher, Mark D. Hylarides, Theodore A. Gooley, Amelia Waltman, Brian G. Till and Oliver W. Press
Shyril O'Steen
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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  • For correspondence: sosteen@fredhutch.org
Damian J. Green
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
2Department of Medicine, University of Washington, Seattle, Washington.
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Ajay K. Gopal
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
2Department of Medicine, University of Washington, Seattle, Washington.
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Johnnie J. Orozco
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
2Department of Medicine, University of Washington, Seattle, Washington.
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Aimee L. Kenoyer
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Yukang Lin
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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D. Scott Wilbur
3Department of Radiation Oncology, University of Washington, Seattle, Washington.
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Donald K. Hamlin
3Department of Radiation Oncology, University of Washington, Seattle, Washington.
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Darrell R. Fisher
5Versant Physics, Richland, Washington.
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Mark D. Hylarides
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Theodore A. Gooley
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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Amelia Waltman
6University of Chicago, Chicago, Illinois.
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Brian G. Till
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
2Department of Medicine, University of Washington, Seattle, Washington.
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Oliver W. Press
1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
2Department of Medicine, University of Washington, Seattle, Washington.
4Department of Bioengineering, University of Washington, Seattle, Washington.
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DOI: 10.1158/0008-5472.CAN-17-0082 Published July 2017
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Article Information

Volume 77, Issue 14, pp. 3885-3893

DOI 
https://doi.org/10.1158/0008-5472.CAN-17-0082
PubMed 
28566329

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received January 10, 2017
  • Revision received March 30, 2017
  • Accepted May 23, 2017
  • Published first May 31, 2017.

Article Versions

  • Previous version (May 31, 2017 - 07:08).
  • Previous version (June 14, 2017 - 06:34).
  • Previous version (June 30, 2017 - 09:36).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2017 American Association for Cancer Research.

Author Information

  1. Shyril O'Steen1,*,
  2. Damian J. Green1,2,
  3. Ajay K. Gopal1,2,
  4. Johnnie J. Orozco1,2,
  5. Aimee L. Kenoyer1,
  6. Yukang Lin1,
  7. D. Scott Wilbur3,
  8. Donald K. Hamlin3,
  9. Darrell R. Fisher5,
  10. Mark D. Hylarides1,
  11. Theodore A. Gooley1,
  12. Amelia Waltman6,
  13. Brian G. Till1,2, and
  14. Oliver W. Press1,2,4
  1. 1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  2. 2Department of Medicine, University of Washington, Seattle, Washington.
  3. 3Department of Radiation Oncology, University of Washington, Seattle, Washington.
  4. 4Department of Bioengineering, University of Washington, Seattle, Washington.
  5. 5Versant Physics, Richland, Washington.
  6. 6University of Chicago, Chicago, Illinois.
  1. ↵*Corresponding Author:
    Shyril O'Steen, Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., MS: D3-190, Seattle, WA 98109. Phone: 206-667-7035; Fax: 206-667-1874; E-mail: sosteen{at}fredhutch.org
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Cancer Research: 77 (14)
July 2017
Volume 77, Issue 14
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Venetoclax Synergizes with Radiotherapy for Treatment of B-cell Lymphomas
Shyril O'Steen, Damian J. Green, Ajay K. Gopal, Johnnie J. Orozco, Aimee L. Kenoyer, Yukang Lin, D. Scott Wilbur, Donald K. Hamlin, Darrell R. Fisher, Mark D. Hylarides, Theodore A. Gooley, Amelia Waltman, Brian G. Till and Oliver W. Press
Cancer Res July 15 2017 (77) (14) 3885-3893; DOI: 10.1158/0008-5472.CAN-17-0082

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Venetoclax Synergizes with Radiotherapy for Treatment of B-cell Lymphomas
Shyril O'Steen, Damian J. Green, Ajay K. Gopal, Johnnie J. Orozco, Aimee L. Kenoyer, Yukang Lin, D. Scott Wilbur, Donald K. Hamlin, Darrell R. Fisher, Mark D. Hylarides, Theodore A. Gooley, Amelia Waltman, Brian G. Till and Oliver W. Press
Cancer Res July 15 2017 (77) (14) 3885-3893; DOI: 10.1158/0008-5472.CAN-17-0082
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Cancer Research Online ISSN: 1538-7445
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