Abstract 6406: FAK and MEK co-targeting: A new multimodal precision therapy for GNAQ-driven uveal melanoma

Justine S. Paradis; Monica Acosta; Nadia Arang; Robert Saddawi-Konefka; Ayush Kishore; Takahito Sugase; Xiaodong Feng; Kris C. Wood; Silvia Coma; Mizue Terai; Takami Sato; Jonathan A. Pachter; J. Silvio Gutkind

doi:10.1158/1538-7445.AM2020-6406

Experimental and Molecular Therapeutics

Abstract 6406: FAK and MEK co-targeting: A new multimodal precision therapy for GNAQ-driven uveal melanoma

Justine S. Paradis, Monica Acosta, Nadia Arang, Robert Saddawi-Konefka, Ayush Kishore, Takahito Sugase, Xiaodong Feng, Kris C. Wood, Silvia Coma, Mizue Terai, Takami Sato, Jonathan A. Pachter and J. Silvio Gutkind

Justine S. Paradis

1UCSD, La Jolla, CA;

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Monica Acosta

1UCSD, La Jolla, CA;

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Nadia Arang

1UCSD, La Jolla, CA;

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Robert Saddawi-Konefka

1UCSD, La Jolla, CA;

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Ayush Kishore

1UCSD, La Jolla, CA;

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Takahito Sugase

2Jefferson University, Philadelphia, PA;

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Xiaodong Feng

1UCSD, La Jolla, CA;

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Kris C. Wood

3Duke University, Durham, NC;

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Silvia Coma

4Verastem, Needham, MA;

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Mizue Terai

5Jefferson University, Philadephia, PA.

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Takami Sato

5Jefferson University, Philadephia, PA.

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Jonathan A. Pachter

4Verastem, Needham, MA;

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J. Silvio Gutkind

1UCSD, La Jolla, CA;

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DOI: 10.1158/1538-7445.AM2020-6406 Published August 2020

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Volume 80, Issue 16 Supplement, pp. 6406

DOI

https://doi.org/10.1158/1538-7445.AM2020-6406

Published By

American Association for Cancer Research

Print ISSN

0008-5472

Online ISSN

1538-7445

Author Information

Justine S. Paradis1,
Monica Acosta1,
Nadia Arang1,
Robert Saddawi-Konefka1,
Ayush Kishore1,
Takahito Sugase2,
Xiaodong Feng1,
Kris C. Wood3,
Silvia Coma4,
Mizue Terai5,
Takami Sato5,
Jonathan A. Pachter4, and
J. Silvio Gutkind1

¹UCSD, La Jolla, CA;
²Jefferson University, Philadelphia, PA;
³Duke University, Durham, NC;
⁴Verastem, Needham, MA;
⁵Jefferson University, Philadephia, PA.

August 2020
Volume 80, Issue 16 Supplement

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Abstract 6406: FAK and MEK co-targeting: A new multimodal precision therapy for GNAQ-driven uveal melanoma

Cancer Res August 15 2020 (80) (16 Supplement) 6406; DOI: 10.1158/1538-7445.AM2020-6406

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Abstract 6406: FAK and MEK co-targeting: A new multimodal precision therapy for GNAQ-driven uveal melanoma

Cancer Res August 15 2020 (80) (16 Supplement) 6406; DOI: 10.1158/1538-7445.AM2020-6406

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