Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer

Piotr Przanowski; Song Lou; Rachisan Djiake Tihagam; Tanmoy Mondal; Caroline Conlan; Gururaj Shivange; Ilyas Saltani; Chandrajeet Singh; Kun Xing; Benjamin B. Morris; Marty W. Mayo; Luis Teixeira; Jacqueline Lehmann-Che; Jogender Tushir-Singh; Sanchita Bhatnagar

doi:10.1158/0008-5472.CAN-20-1459

Tumor Biology and Immunology

Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer

Piotr Przanowski, Song Lou, Rachisan Djiake Tihagam, Tanmoy Mondal, Caroline Conlan, Gururaj Shivange, Ilyas Saltani, Chandrajeet Singh, Kun Xing, Benjamin B. Morris, Marty W. Mayo, Luis Teixeira, Jacqueline Lehmann-Che, Jogender Tushir-Singh and Sanchita Bhatnagar

Piotr Przanowski

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Song Lou

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Rachisan Djiake Tihagam

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Tanmoy Mondal

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Caroline Conlan

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Gururaj Shivange

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Ilyas Saltani

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Chandrajeet Singh

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Kun Xing

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Benjamin B. Morris

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

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Marty W. Mayo

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

2UVA Cancer Center, University of Virginia School of Medicine, Charlottesville, Virginia.

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Luis Teixeira

3Breast Disease Unit, AP-HP, Hospital Saint Louis, Paris, France.

4University of Paris, INSERM U976, HIPI, IRSL-Saint Louis, Paris, France.

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Jacqueline Lehmann-Che

4University of Paris, INSERM U976, HIPI, IRSL-Saint Louis, Paris, France.

5Molecular Oncology Unit, AP-HP Hospital Saint Louis, Paris, France.

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Jogender Tushir-Singh

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

2UVA Cancer Center, University of Virginia School of Medicine, Charlottesville, Virginia.

6Laboratory of Novel Biologics, University of Virginia School of Medicine, Charlottesville, Virginia.

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For correspondence: sb5fk@virginia.edu jogi@virginia.edu

Sanchita Bhatnagar

1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

2UVA Cancer Center, University of Virginia School of Medicine, Charlottesville, Virginia.

7Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, Virginia.

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For correspondence: sb5fk@virginia.edu jogi@virginia.edu

DOI: 10.1158/0008-5472.CAN-20-1459 Published November 2020

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November 2020
Volume 80, Issue 21

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Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer