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More articles from Poster Presentations - Chemical Biology and Structure-Function Studies of Cancer Mechanisms

Abstract 2457: Mechanisms of membrane binding of K-Ras4B farnesylated hypervariable region
Hyunbum Jang, Sherwin J. Abraham, Tanmay S. Chavan, Ben Hitchinson, Lyuba Khavrutskii, Nadya I. Tarasova, Ruth Nussinov, Vadim Gaponenko

Cancer Research Aug 2015, 75 (15 Supplement) 2457; DOI: 10.1158/1538-7445.AM2015-2457
Abstract 2456: The transmembrane domain of prostate specific membrane antigen: Deciphering the role of the Small-XXX-Small motif in oligomerization
Brianna S. Berg, Brandan M. Cook, Jack R. Hyder, James I. Godfroy, Hubert Yin, Jonel P. Saludes

Cancer Research Aug 2015, 75 (15 Supplement) 2456; DOI: 10.1158/1538-7445.AM2015-2456
Abstract 2447: Development of Hsp90 paralog specific inhibitors with mitochondrial drug delivery system
Byoung Heon Kang

Cancer Research Aug 2015, 75 (15 Supplement) 2447; DOI: 10.1158/1538-7445.AM2015-2447
Abstract 2442: XPO1 is selinexor prime target: validation by mutating cysteine 528 on both XPO1 alleles using CRISPR/Cas9 genome editing
Jasper E. Neggers, Thomas Vercruysse, Maarten Jacquemyn, Els Vanstreels, Erkan Baloglu, Sharon Shacham, Marsha Crochiere, William Senapedis, Yosef Landesman, Dirk Daelemans

Cancer Research Aug 2015, 75 (15 Supplement) 2442; DOI: 10.1158/1538-7445.AM2015-2442
Abstract 2454: Targeting the translational enhancer complex MCT-1:DenR to disrupt NHL survival
Sean D. Stowe, Michael C. Cavalier, Raquel Godoy-Ruiz, Kristen J. Varney, Paul T. Wilder, Ronald B. Gartenhaus, David J. Weber

Cancer Research Aug 2015, 75 (15 Supplement) 2454; DOI: 10.1158/1538-7445.AM2015-2454
Abstract 2444: Directed evolution strategy for generating of novel zinc finger peptides with affinity for gapped DNA
Dylan Plaskon, Rachel M. Guerra, Connor P. McGuckin, Vania Lopez Ruiz, Colin T. Sheehan, Ryan A. Weeks, Dylan Cincotta, Kevin P. Rice

Cancer Research Aug 2015, 75 (15 Supplement) 2444; DOI: 10.1158/1538-7445.AM2015-2444
Abstract 2449: Targeting an “undruggable” RNA-binding protein: Discovery of small molecule inhibitors of HuR for novel breast cancer therapy
Xiaoqing Wu, Lan Lan, Amber Smith, Rebecca Marquez, David Wilson, Steven Rogers, Philip Gao, Scott Lovell, John Karanicolas, Dan Dixon, Jeffrey Aubé, Liang Xu

Cancer Research Aug 2015, 75 (15 Supplement) 2449; DOI: 10.1158/1538-7445.AM2015-2449
Abstract 2443: Optides (optimized peptides), a new knottin-based cancer drug discovery platform
James M. Olson, Roland Strong, Christopher Mehlin, Colin Correnti

Cancer Research Aug 2015, 75 (15 Supplement) 2443; DOI: 10.1158/1538-7445.AM2015-2443
Abstract 2448: Towards structure-based drug design of 3-phosphoglycerate dehydrogenase inhibitors
Judith E. Unterlass, Nabila Aljufri, Sophie Bex, Celine Cano, Martin E M Noble, Nicola J. Curtin

Cancer Research Aug 2015, 75 (15 Supplement) 2448; DOI: 10.1158/1538-7445.AM2015-2448
Abstract 2446: Decoding phenotypic drug screening targets using a novel chloroalkane capture tag
Rachel Friedman Ohana, Thomas Kirkland, Carolyn Woodroofe, Sergiy Levin, Robin Hurst, Paul Otto, Tetsuo Uyeda, Michael Ford, Richard Jones, Danette Daniels, Marjeta Urh, Keith Wood

Cancer Research Aug 2015, 75 (15 Supplement) 2446; DOI: 10.1158/1538-7445.AM2015-2446

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