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More articles from Poster Presentations - DNA Double-Strand Break Repair Defects in Cancer: Therapeutic Strategies and Molecular Basis

Abstract 2748: Targeting DNA repair deficient cancers with the cell-penetrating autoantibody 3E10
Audrey L. Turchick, Peter M. Glazer

Cancer Research Jul 2016, 76 (14 Supplement) 2748; DOI: 10.1158/1538-7445.AM2016-2748
Abstract 2745: A genetic screen to identify tumor suppressive DDR genes in breast cancer
Katerina D. Fagan-Solis, Gaorav P. Gupta

Cancer Research Jul 2016, 76 (14 Supplement) 2745; DOI: 10.1158/1538-7445.AM2016-2745
Abstract 2750: Mutations on the homologous recombination pathway in 13 cancer types
Joanne Xiu, Ryan Bender, Brian Abbott, Zoran Gatalica, Sandeep Reddy, Mohamed Salem, Shelly Seward

Cancer Research Jul 2016, 76 (14 Supplement) 2750; DOI: 10.1158/1538-7445.AM2016-2750
Abstract 2746: Combined inhibition of Wee1 and Poly(ADP Ribose)Polymerase 1/2 synergistically inhibits acute leukemia cells by enhancing DNA damage and inducing apoptosis in vitro and in vivo
Tamara B. Garcia, Jonathan C. Snedeker, Christopher C. Porter

Cancer Research Jul 2016, 76 (14 Supplement) 2746; DOI: 10.1158/1538-7445.AM2016-2746
Abstract 2758: FANCF, a Fanconi anemia core complex protein involved in monoubiquitination of FANCD2, also has a role with nuclear alpha spectrin in DNA interstrand crosslink repair
Muriel W. Lambert, Deepa Sridharan, Pan Zhang

Cancer Research Jul 2016, 76 (14 Supplement) 2758; DOI: 10.1158/1538-7445.AM2016-2758
Abstract 2753: Landscape of somatic mutations in DNA repair genes in prostate cancer
Santosh Yadav, Muralidharan Anbalagan, Melody Baddoo, Erik Flemington, Krzysztof Moroz, Kathleen Hering-Smith, Nick Makridakis

Cancer Research Jul 2016, 76 (14 Supplement) 2753; DOI: 10.1158/1538-7445.AM2016-2753
Abstract 2752: Characterization of the ATM-SPOP pathway in prostate cancer tumorigenesis
Joshua Fried, Rebecca Boohaker, Qinghua Zeng, Wei Zhang, Bo Xu

Cancer Research Jul 2016, 76 (14 Supplement) 2752; DOI: 10.1158/1538-7445.AM2016-2752
Abstract 2754: Antibody-based tools for in vitro and live cell analysis of endogenous PARP1, an essential human DNA repair enzyme
Andrea Buchfellner, Larisa Yurlova, Stephanie Dennison, Benjamin Ruf, Ulrich Rothbauer, Tina Romer

Cancer Research Jul 2016, 76 (14 Supplement) 2754; DOI: 10.1158/1538-7445.AM2016-2754
Abstract 2756: SMARCAD1 depletion enhances hyperthermia-mediated radiosensitization by decreasing resection and enhancing stalled replication forks
Sharmistha Chakraborty, Clayton R. Hunt, Shashank Hambarde, Kalpana Mujoo, Nobuo Horikoshi, Raj K. Pandita, Abid Mattoo, Bin Teh, Tej K. Pandita

Cancer Research Jul 2016, 76 (14 Supplement) 2756; DOI: 10.1158/1538-7445.AM2016-2756
Abstract 2749: A novel small molecule inhibitor targets the DNA double strand break repair protein Ku70/80
Daruka Mahadevan, Alfred C. Gallegos, Lauren N. Dominick, Laurence S. Cooke, Trace N. Bartels, Josef Vagner, Terry O. Matsunaga, Eric Weterings

Cancer Research Jul 2016, 76 (14 Supplement) 2749; DOI: 10.1158/1538-7445.AM2016-2749

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